This thesis addresses the challenge of supporting novice programmers in the GenAI era without undermining fundamental skill acquisition. Using digital activity logs, self-reported characteristics, and GenAI usage patterns from an introductory programming course, it develops models that capture student learning behaviors. These models are then used to create personalized AI-based intervention strategies that guide students toward independent problem-solving.
Multimodal emotion and sentiment recognition is commonly addressed by early fusion, which concatenates modalities before classification, or late fusion, which combines independently trained unimodal predictors. Early fusion can be accurate but monolithic, while late fusion is modular but may lose cross-modal interactions. This paper revisits XAI-guided adaptive fusion (\xgaf), a tree-based mixture of unimodal and cross-modal experts whose sample-level weights are derived from TreeSHAP attribution magnitudes. We focus on the effect of SHAP attribution reduction when experts have unequal feature dimensionalities. In this setting, mean-abs and median-abs reductions can suppress high-dimensional cross-modal experts, whereas sum-abs reduction preserves total attribution mass. On MELD 7-class emotion recognition, sum-abs \xgaf{} nearly matches early fusion across three face-sequence aggregators; the Transformer variant reaches 0.5983 \wf{}, compared with 0.6018 for early fusion and 0.4598 for probability-average late fusion. McNemar testing shows no significant difference between sum-abs \xgaf{} and early fusion on MELD ($p=1.000$), while \xgaf{} remains significantly better than late fusion ($p<0.0001$). On CMU-MOSEI 3-class sentiment recognition, sum-abs \xgaf{} reaches 0.6519 \wf{}, slightly exceeding early fusion (0.6485) and late fusion (0.5696). Ablation studies show that the main gain comes from adding cross-modal experts, especially the trimodal expert, rather than from complex per-sample routing. Diagnostics further show that mean-abs and median-abs weights are nearly uniform, while sum-abs weights concentrate on the trimodal expert. Thus, the main contribution is a transparent empirical analysis of how SHAP reduction, expert dimensionality, and cross-modal expert design affect modular multimodal fusion.
The Carpathian water buffalo represents a locally adapted but under-characterized genetic group found in Central and Eastern Europe. Genome-wide information on its genetic diversity, population structure and potential adaptive variation remains limited, particularly for Hungarian and Romanian populations. In this study, we genotyped 263 water buffalo individuals from Hungary and Romania using the GeneSeek Genomic Profiler Bovine 100K SNP array to evaluate genetic diversity, the population structure, runs of homozygosity (ROH) and candidate genomic regions showing signatures of selection. After quality control, 214 Hungarian and 33 Romanian individuals and 6605 SNPs were retained for downstream analyses. Both populations showed moderate genetic diversity, with the Romanian population displaying higher minor allele frequency, observed heterozygosity and nucleotide diversity than the Hungarian population. In contrast, the Hungarian buffalo showed a higher burden of runs of homozygosity, including a larger proportion of long ROH segments, suggesting stronger recent autozygosity or a more restricted breeding structure. Principal component analysis and neighbor-joining phylogeny separated the two populations, whereas ADMIXTURE indicated shared ancestry and a within-population substructure rather than complete population-specific differentiation. The integration of standardized FST, absolute allele-frequency differences and ROH islands identified six candidate regions under a positive signature of selection in each population. These regions harbored genes previously associated with immune response, reproduction, growth, milk production and thermotolerance in bovids. Functional enrichment was limited, with significant Gene Ontology terms detected only in the Hungarian candidate regions. Our results provide a regional genomic baseline for the future conservation and breeding management of Carpathian water buffalo. Given the use of a cross-species SNP array and unequal sample sizes, the candidate selection signals should be interpreted as hypothesis-generating and warrant validation using higher-density buffalo-specific genomic data.
Background/Objectives: Hypertrophic cardiomyopathy (HCM) is a complex myocardial disease in which structural remodeling extends beyond conventional parameters such as maximal wall thickness (MWT). This study aimed to evaluate isoperimetric analysis as a geometry-based approach for characterizing left ventricular (LV) morphology and to compare its performance with fractal analysis in distinguishing HCM from non-HCM subjects. Methods: This retrospective study included 120 subjects (60 HCM and 60 controls) who underwent clinically indicated CMR. Endocardial contours were delineated on short-axis cine images at end-diastole. The isoperimetric index (IPI), cavity-corrected IPI (CC-IPI), and fractal dimension (FD) were calculated. Group comparisons, correlations, and receiver operating characteristic analyses were performed. Results: Patients with HCM showed significantly higher IPI and CC-IPI values than controls (p < 0.001), including in sex-stratified analyses. IPI and CC-IPI correlated strongly with MWT (r = 0.867) and LV mass index (r = 0.807 and 0.803, respectively), moderately with native T1 (r = 0.567), and weakly with end-diastolic volume index (r = 0.256 and 0.253, respectively) and stroke volume (r = 0.237 and 0.229, respectively). No association was observed with late gadolinium enhancement. IPI and CC-IPI showed a strong linear correlation (R2 = 0.997), with both indices demonstrating high discriminatory performance (AUC = 1.00). Conclusions: HCM is associated with notable alterations in LV endocardial geometry beyond myocardial hypertrophy alone. IPI and CC-IPI provide simple, size-normalized, and physiologically interpretable morphologic descriptors that complement conventional CMR parameters and FD-based contour complexity analysis.
Agroecological conditions, the biological characteristics of grapevine varieties, and the application of viticultural practices significantly influence the physico-chemical properties of grapes. This study assessed the impact of agroecological conditions at two cultivation sites, Sarajevo and Trebinje, on the physico-chemical properties of Chardonnay and Cabernet Sauvignon (Vitis vinifera L.) grape varieties. The results showed that location had a statistically significant effect on several physical parameters of grape bunches and berries. Significant differences were observed in bunch and berry mass (in ‚Chardonnay‘), bunch length (in both varieties), bunch width (in ‚Cabernet Sauvignon‘), berry length (in ‚Chardonnay‘), berry width (both varieties), as well as in the mass of 100 berries, pulp and skin mass of 100 berries, and the number of seeds per 100 berries. Furthermore, the cultivation site significantly influenced the sugar and total acid content in both varieties, as well as the phenolic content in ‚Chardonnay‘ berries, and the flavonoid content and total antioxidant activity in ‚Cabernet Sauvignon‘.
Rad analizira usklađenost Zakona o zaštiti ličnih podataka iz 2025. (ZZLP) s Općom uredbom o zaštiti podataka (GDPR), kao i njegov odnos prema općim pravilima odštetnog prava sadržanim u Zakonu o obligacionim odnosima (ZOO). Iako ZZLP kao lex specialis i lex posterior ima prednost u primjeni, ispitano je da li određene nedorečenosti ili kolizije između ova dva zakona podrivaju temeljni cilj GDPR-a – osiguranje djelotvornih, odvraćajućih i razmjernih pravnih sredstava. Utvrđen je visok stepen normativne usklađenosti ZZLP-a s GDPR-om, naročito u pogledu administrativnih i krivičnih sankcija. Međutim, značajna odstupanja uočena su u oblasti naknade štete. Sudska praksa Suda Evropske unije potvrđuje da ne postoji pravilo de minimis, da šteta mora biti stvarna i dokaziva, te da naknada ima isključivo kompenzacijski karakter. Budući da je BiH kandidat za članstvo u EU, ovi standardi su relevantni i za domaće sudove. Ključni problem identificiran je u pitanju uzročnosti i štete, koju ZZLP ne uređuje detaljno, pa se primjenjuju pravila ZOO. Dokazivanje uzročnosti može otežati ostvarivanje zaštite, zbog čega se razmatra mogućnost kvalifikacije obrade podataka kao opasne djelatnosti, čime bi se teret dokazivanja prebacio na obrađivača. Posebno su analizirana pitanja materijalne i nematerijalne štete. Kod materijalne štete, mali iznosi mogu obeshrabriti oštećene, pa se razmatra potencijalna uloga nominalne ili kaznene štete, uprkos restriktivnom stavu Suda EU. Najveći nesklad između ZZLP/GDPR i ZOO odnosi se na nematerijalnu štetu. Dok GDPR i ZZLP dopuštaju naknadu neovisno o intenzitetu i trajanju povrede, ZOO polazi od subjektivnog koncepta koji zahtijeva određeni prag bola ili straha. Stoga se predlaže de lege ferenda prelazak na objektivnu koncepciju nematerijalne štete, prema kojoj sama povreda ličnih prava predstavlja štetu, dok bi intenzitet bola i straha služio samo za određivanje visine naknade. Također su kritizirane procesne manjkavosti, uključujući izostanak alternativne mjesne nadležnosti i nedostatak odredbi o kolektivnoj zaštiti prava. Ključne riječi: zaštita osobnih podataka, GDPR, naknada štete za povredu osobnih podataka, nematerijalna šteta, kolektivna zaštita.
In the last few decades, bark beetle outbreaks have increased in European forests, triggered by extreme weather events, such as drought and windstorms. A core element of integrated pest management to control outbreaks are salvage logging and sanitation felling, i.e., the timely removal or treatment of potential brood material and already infested trees after disturbance events. Associated with these management operations as well as with regular, planned thinning and cutting, felling residues, such as treetops, branches and stumps that remain in the forest provide potentially suitable breeding material for bark beetles and may trigger further outbreak events. Although felling residue management is part of regular forest management in most of Europe, no overview exists on its use throughout the continent. To fill this gap, we gathered forest health experts from 20 European countries and used a questionnaire to provide information on felling residue management in the context of forest protection in managed forests. Relevant legislation in these countries was reviewed for regulations concerning this topic. We found that most countries have felling residue management in their legislation and/or perform it in practice. In 12 of the 20 countries, felling residue management is being applied to manage bark beetles, particularly in areas that have experienced large-scale outbreaks in the last few decades. Felling residues are mainly managed in forests dominated by Norway spruce (Picea abies L. Karst) and pines (Pinus spp.) (in 19 and 17 of the countries, respectively). The most frequently used management methods on a European level were piling or mulching of felling residues. These methods were used in 14 and 16 of the countries, respectively. Besides bark beetle management, use of residues for bioenergy (4 countries) and biodiversity conservation (6 countries) was reported. The diversity of felling residue management practices across Europe may reflect differences in forest policies and climatic gradients that are affecting bark beetle outbreak risks. This overview presents the variety of felling residue management applied across 20 European countries, highlighting the reasons for and implications of its use, as well as further research needs.
Background: The Renal Registry of Bosnia and Herzegovina systematically collects national data on kidney replacement therapy for patients with end-stage kidney disease (ESKD). This report summarizes 2 decades of registry data (2002-2022), showing trends in incidence, prevalence, modality distribution, and patient outcomes. Methods: Data were obtained annually from 30 dialysis centers across the country. Incidence, prevalence, and survival rates for hemodialysis (HD), peritoneal dialysis (PD), and kidney transplantation were calculated per million population (pmp). Descriptive statistics and Kaplan–Meier survival analyses were performed using SPSS 25. Results: Between 2002 and 2022, the number of dialysis centers increased from 18 to 30, and the total treated population rose by 43.5% (from 1687 to 2421 patients). Hemodialysis remained the predominant modality (80.4%), while PD accounted for only 3.0% of all dialysis patients. The incidence rate in 2022 was 118.9 pmp, and the prevalence reached 685.6 pmp. The leading causes of ESKD were diabetic nephropathy (29.5%) and hypertensive nephropathy (13.1%). The crude mortality rate among dialysis patients in 2022 was 13.2%, primarily due to cardiovascular disease. By the end of 2022, a total of 402 patients lived with a functioning kidney graft. Conclusion: Over the past 2 decades, Bosnia and Herzegovina has experienced steady growth in its dialysis population and gradual improvements in registry coverage. However, the country continues to face challenges, including low utilization of PD and limited transplantation activity. Strengthening early chronic kidney disease detection and expanding organ donation programs remain key national priorities. Cite this article as: Resić H, Rebić D, Turković AM. The renal registry of Bosnia and Herzegovina. Turk J Nephrol. Published online May 11, 2026. doi: 10.10.5152/turkjnephrol.2026.25988.
Novi regulatorni okvir za industrijski dizajn u EU, utemeljen na Uredbi (EU) 2024/2822 i Direktivi (EU) 2024/2823, donosi značajnu modernizaciju sustava zaštite koji nije mijenjan više od 20 godina. Glavne novosti uključuju proširenje definicije proizvoda, klauzula o popravku, suzbijanje 3D ispisa, promjenu terminologije, kao i moderne prikaze dizajna. Veći dio pravila počeo se primjenjivati od svibnja 2025., dok države članice imaju rok do kraja 2027. za potpuno usklađivanje nacionalnih zakona s novom Direktivom (EU) 2024/2823, kako bi se modernizirao sustav i prilagodio izazovima digitalnog doba. U radu će se analizirati razlozi zbog koji su usvojena nova pravila, te sudska praksa koja je oblikovala nova rješenja odnosno kako Sud EU-a kroz svoju praksu stvara pravni okvir koji paketu reformi dizajna daje snagu i koherentnost. Ključne riječi: industrijski dizajn, Uredba (EU) 2024/2822, Direktiva (EU) 2024/2823, klauzula o popravku, suzbijanje 3D ispisa.
Real-time prediction of complex physical systems requires surrogate models that learn from data while representing strong multiphysics coupling. Deep Operator Networks have shown success in single-physics problems, yet their effectiveness in capturing nonlinear interactions in coupled systems (such as thermo-mechanical or electro-thermal coupling) remains underexplored. Here we pose a practical question: should the architecture of a neural operator reflect the strength of physical coupling it aims to model? We compare single-branch and multi-branch designs, in both feedforward and sequential recurrent forms, across three representative systems: a reaction-diffusion problem with heterogeneous sources, a nonlinear thermo-electrical problem with temperature-dependent conductivity and Joule heating, and a viscoplastic thermo-mechanical model of steel solidification. Single-branch networks consistently outperform multi-branch variants in tightly coupled regimes by encouraging shared latent representations, whereas multi-branch designs remain favorable for decoupled or single-physics tasks. Once trained, these surrogates deliver full-field predictions up to 1.8 × 104 times faster than physics-based solvers.
Background/Objectives: Pharmacists play a key role in managing urinary tract infection (UTI) symptoms by providing medications, self-care advice, and over-the-counter treatments, while referring patients to a doctor when necessary. This study aimed to examine the practices of community pharmacists in managing UTI symptoms and to gain insight into their attitudes toward antibiotic use for this condition. Methods: A cross-sectional study was conducted among community pharmacists in Serbia using a previously validated online questionnaire, assessed for content and face validity and pilot-tested among pharmacists. Results: A total of 430 community pharmacists participated in the study. Patients more often consulted pharmacists before visiting a doctor than after (median 5 vs. 3 per week; p < 0.001). For uncomplicated UTIs, pharmacists primarily recommended increased fluid intake (92.8%), herbal teas (94.7%), and food supplements (85.6%), whereas for complicated UTIs, most referred patients to a doctor (95.4%). Attitudes, perceived competence, and support for over-the-counter antibiotic availability were significantly associated with gender, years of experience, and specialization. Pharmacists who agreed that antibiotics are the most effective treatment for uncomplicated urinary tract infections were more likely to refer patients to a doctor (p < 0.01). Conclusions: Pharmacists are frequently consulted for UTI management and emphasize non-antibiotic approaches for uncomplicated cases. Their attitudes influence counseling practices, highlighting the need for standardized UTI counseling services, antimicrobial stewardship education, and structured communication training to support appropriate antibiotic use.
The aim of this study was to examine the impact of perceived stress levels on anxiety and depression among parents of children with disabilities. The study included a sample of 104 parents of children with different types of disabilities, of whom 85.6% were mothers and 14.4% were fathers. The Perceived Stress Scale (PSS-10) was used to assess the level of perceived stress, the Generalized Anxiety Disorder Scale (GAD-7) was used to assess anxiety, and the Patient Health Questionnaire (PHQ-9) was used to assess depression. Data were analyzed using descriptive statistics and linear regression analysis. The results indicated the presence of a moderate level of anxiety (M = 11.17; SD = 4.53), a moderately severe level of depression (M = 15.92; SD = 6.60), and a high level of perceived stress (M = 28.73; SD = 5.11) among parents of children with disabilities. Linear regression analysis showed that the level of perceived stress was a statistically significant predictor of anxiety (R² =0.25; p < 0.001) and depression (R² = 0.27; p < 0.001). The obtained findings indicate that higher levels of perceived stress contribute to higher levels of anxiety and depression among parents of children with disabilities. The study results highlight the need for the development of systematic psychological and social support for parents of children with disabilities in order to preserve their mental health. Keywords:perceived stress, anxiety, depression, parents of children with disabilities, mental health, psychological burden
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