Environmental noise management is a critical aspect of public health policy, particularly within the European Union, which established Directive 2002/49/EC to standardize noise assessment and mitigation efforts across member states. Serbia has integrated the Directive's provisions through its Law on Environmental Noise Protection and accompanying by-laws. This paper presents the strategic noise mapping process for Belgrade Nikola Tesla Airport, Serbia's largest international airport, marking a significant milestone as it is the first time a strategic noise map is being developed for a major airport in Serbia. The legal framework, methodology, and results of this mapping process are discussed in detail. Utilizing the CNOSSOS-EU:2015 method and the Aviation Environmental Design Tool (AEDT) for acoustic calculations, the study defines the affected areas, noise indicators, and population exposure based on 2023 air traffic data. The results indicate that the Lden noise levels exceeding 55 dB impacted 24,223 residents, while the Lnight noise levels exceeding 50 dB affected 7,493 residents. The analysis also includes the estimated number of dwellings, schools, hospitals, and people affected by different noise levels, providing necessary data for developing action plans aimed at mitigating noise pollution. Additionally, the study examines the potential health impacts, including population annoyance and sleep disturbance, using dose-effect relationships as defined by the European Commission. The results underline the importance of ongoing noise monitoring and the need for timely revisions of strategic noise maps and action plans to ensure compliance with both national and EU regulations. This research contributes to the broader effort of environmental noise management, offering insights into the methodologies and challenges of strategic noise mapping for airports in Serbia.
In the face of pressing socio-economic and environmental challenges, such as climate change, resource depletion, and social inequality, entrepreneurs are increasingly compelled to embrace innovative strategies that harmonize profitability with social and environmental stewardship. Artificial Intelligence (AI) holds promise in facilitating such solutions but requires careful examination to ensure its effective and ethical deployment in pursuit of sustainability objectives. The primary goal of this study was to ascertain whether AI significantly influences the sustainable entrepreneurial process. This comprehensive research framework integrates concepts from entrepreneurship, stakeholder theory, and digital technology, offering a multifaceted perspective. We employed the multiple regression analysis to examine data gathered from 40 entrepreneurs operating within the Bosnia and Herzegovina settings. The study's outcomes revealed that AI positively and significantly impacts the sustainable entrepreneurial process and its five sub-dimensions: “idea generation, opportunity recognition, opportunity development, venture launch, and positive impact”. This study enriches the literature on AI and sustainable entrepreneurship by offering empirical support for the impact of AI on the sustainable entrepreneurial process while also introducing and validating measurement tools for the sustainable entrepreneurial process. Additionally, entrepreneurs can utilize the findings of this research to strategically incorporate AI into their business processes and product/service innovation, improve operational efficiency, reduce costs, mitigate risks, enhance decision-making, foster collaboration across stakeholders, and capitalize on opportunities effectively.
The aim of this paper is to present a case of infective endocarditis (IE) caused by Staphylococcus aureus (S. aureus), focusing on diagnostic and therapeutic approaches. The paper highlights the importance of 2D transesophageal echocardiography (TOE) and discusses the capabilities and advances of appliance of the 3D TOE in patient evaluation, better understanding of the diagnosis, and timely treatment. The use of this advance echocardiographic modality allows clear visualization of complex and destructive tissue lesions, such as the perforation observed and presented in this case.
The study was conducted on the Obedska Bara Ramsar site at two localities, Krstonošića okno and canal Vok, to provide insight into fish community status by analysing fish biomass, biodiversity, and changes after restoration measures. A total of 685 fish samples were examined across four periods, from 2011 to 2023. Biodiversity index, relative biomass, and non-native species were analysed to evaluate the restoration measures’ influence. All parameters showed a negative trend until the restoration works were implemented, after which they increased. This study also provides recommendations to improve the site considering the Mission Restore our Ocean and Waters by 2030.
<p lang="hr-HR" align="JUSTIFY"><strong>Aim</strong> Moderate to severe asthma patients with sufficient and insufficient vitamin D serum level, respectively, were assessed with quality of life questionnaires before and after treatment with vitamin D added to their standard asthma treatment.<br /><strong>Methods</strong> Patients with moderate to severe asthma have been divided into two groups based on a serum level of vitamin D as sufficient or insufficient level of vitamin D, respectively. During 12 months, a total of 120 patients with sufficient level of vitamin D as well as 120 patients with insufficient level were given treatment with 2000 IU vitamin D for a three-month period. Quality of life of all patients was assessed by Asthma Control Test (ACT), Asthma Quality of Life (AQOL) and the physician's assessment expressed through the Global Evaluation of Treatment Effectiveness (GETE), which were performed before and after the treatment with Vitamin D.<br /><strong>Results</strong> Values of ACT and AQOL were higher after the treatment with vitamin D in both groups of patients. Values of GETE were lower after the treatment with vitamin D in both groups. All assessed components, psychological, physical, as well as the subjective feeling of control of the disease assessed by treating physicians, showed improvement after treatment.<br /><strong>Conclusion</strong> Adding vitamin D in the treatment regimen of moderate to severe asthma patients improves quality of life and general asthma treatment effectiveness.</p>
<p><strong>Aim</strong> To analyse the impact of age and body mass index (BMI) on dual-energy X-ray absorptiometry (DXA) scan results in postmenopausal women. <br /><strong>Methods</strong> The study included 100 postmenopausal women who underwent the DXA procedure, out of which 50 had a normal BMI and 50 were overweight/obese. Data that were examined included age, BMI, T-score of the lumbar region and the femoral neck, as well as bone mineral density (BMD). Correlation results were presented as Pearson’s correlation coefficient (r). <br /><strong>Results</strong> The T2-score and BMD2 were significantly lower in older patients compared to younger ones (p=0.008 and p=0.007, respectively). Post hoc test results showed that the T2-score and BMD2 were significantly lower in patients ≥71 years of age compared to patients ≤59 years of age (p=0.006 and p=0.005, respectively). Also, T1- and T2-scores, as well as BMD1 and BMD2, were significantly higher in overweight/obese patients (p<0.001 and p=0.003; p<0.001 and p=0.002, respectively). The correlation between BMI and the T1-score was moderate (r=0.429), between BMI and the T2-score weak (r=0.348), between BMI and BMD1 moderate (r=0.431), and between BMI and BMD2 weak (r=0.344). <br /><strong>Conclusion</strong> Our study showed that both age and BMI are important factors affecting DXA procedures and should be taken into account with each postmenopausal woman individually in everyday practice.</p>
This study introduces a translation perspective to analyze the policy harmonization process, highlighting imitation, brokering, and editing in shaping policy dynamics at EU and national levels. The translation perspective emphasizes that while policy development is ongoing, the protracted process signals a shift in EU‐wide coordination of skilled labor migration. We show how ongoing translation efforts have transformed the coordination of skilled labor migration across the EU, as labor migration policies have translated into each other, resulting in mutual transformation. The study provides insights into the complex processes of policy harmonization via the Blue Card, enhancing understanding of EU labor migration policy. The findings demonstrate the continuous nature of policy translation between multiple contexts. The article traces developments surrounding the EU Blue Card Directive, including a parallel scheme in Austria, offering insights into skilled migration policy dynamics beyond linear diffusion models.
<p><strong>Aim</strong> To determine the effects of high peri- and postoperative doses of vitamin C administration on severity of pain in postoperative period and functional outcome of the patients with trochanteric fracture treated with intramedullary nailing during a three-month follow-up.<br /><strong>Methods</strong> A prospective, randomized, pilot study included 56 patients who were randomly divided into vitamin C (intervention) and control groups. In the intervention group, patients received vitamin C perioperatively by an intravenous route for 2 days, and oral vitamin C for 38 days postoperatively. Baseline characteristics, postoperative metamizole consumption, Visual Analogue Scale (VAS) score, Harris Hip Score (HHS) value, and the prevalence of complications were evaluated in both groups. <br /><strong>Results</strong> No significant differences were noted between the groups regarding age, gender, length of hospitalization, and distribution in fracture type. Postoperative metamizole consumption was notably higher in the control group compared to the vitamin C group (p=0.006). Postoperative VAS score was higher in the control group (p<0.05). No significant differences in HHS values were detected between the groups at 6 and 12 weeks postoperatively (p=0.655 and p=0.755, respectively). The group variable significantly contributed to VAS score, and age and gender variables significantly contributed to HHS value.<br /><strong>Conclusion</strong> A significant reduction of subjective pain levels and lower analgesic consumption was found in patients who received vitamin C, suggesting that it should be considered as an adjuvant agent for analgesia in patients with hip fracture.</p>
<p><strong>Aim</strong> To investigate immigrant women's experiences of childbirth in Swedish maternity care.<br /><strong>Methods</strong> A systematic search was conducted in PubMed, Embase, CINAHL, and Web of Science for qualitative and quantitative literature on immigrant women's experiences with Swedish maternity care. An inductive thematic analysis generated themes and subthemes.<br /><strong>Results</strong> Sixteen studies were included in this research. The three main themes were access to healthcare, professional treatment, and feeling significant in care. Key findings revealed that immigrant women struggled with trauma, difficult interactions with midwives, communication issues, interpreter problems, lack of detailed information, the role of doulas, and future concerns.<br /><strong>Conclusion</strong> Immigrant women's experiences of Swedish maternity care were marked by information gaps, ignorance, and disrespect, leading to mistrust and delayed help-seeking. Language barriers with midwives caused misunderstandings. A sense of belonging to Swedish society was crucial for a positive experience. More qualitative research, education in transcultural care, and training in interpreter use are needed to improve maternity care for foreign women.</p>
Microneedles (MNs) are emerging as versatile tools for both therapeutic drug delivery and diagnostic monitoring. Unlike hypodermic needles, MNs achieve these applications with minimal or no pain and customizable designs, making them suitable for personalized medicine. Understanding the key design parameters and the challenges during contact with biofluids is crucial to optimizing their use across applications. This review summarizes the current fabrication techniques and design considerations tailored to meet the distinct requirements for drug delivery and biosensing applications. We further underscore the current state of theranostic MNs that integrate drug delivery and biosensing and propose future directions for advancing MNs toward clinical use.
Healthy plantar pressure distribution beneath the feet plays a crucial role in children’s development from the very beginning, with any deviations potentially leading to various pathologic conditions. This review aims to examine recent applications of pedobarographic analysis in pediatrics applications, providing a clearer picture of current research practices and the topics being addressed. The authors conducted a comprehensive search across several scientific databases, including PubMed, Web of Science, Scopus, and Google Scholar, ultimately selecting 17 studies after applying specific criteria for inclusion. The findings demonstrate that pedobarographic analysis can effectively differentiate between age and sex differences in plantar pressure and detect the influence of various risk factors in healthy children. It was found that a child’s foot health is closely linked to their physical activity level, with body fat percentage playing a significant role in pressure distribution. Furthermore, external factors like school bags and internal factors such as obesity were identified as major contributors to abnormal plantar pressure, and pedobarography proved successful in detecting these effects. The analysis also showed that pedobarography is an effective tool for assessing foot health, tracking changes, and monitoring longterm recovery or trends in children. However, the review also highlights a limitation in the scarcity of research, particularly in the areas of gait and plantar pressure in children. Only a few studies have focused on young healthy athletes, suggesting that future research could delve deeper into this population.
Background: COVID-19 is a respiratory disease caused by a novel coronavirus, with a high mortality, especially in patients with underlying diseases. Patients with COVID-19 pneumonia may express an immune response such as cytokine storm or macrophage activation syndrome, which can lead to organ failure and death.Some studies suggest that corticosteroid and tocilizumab can improve the respiratory status and clinical outcome of patients with COVID-19 pneumonia. Aim: The aim of the study was to determine the potential effect of the use of tocilizumab and corticosteroids in patients with concomitant cardiovascular diseases on the clinical course and outcome during COVID-19 infection. Methods: We performed an observational retrospective study of adult patients admitted to “Travnik” and “Jajce” Hospital, Bosnia and Herzegovina, between 01.03.2020 and 01.12.2022 with confirmed COVID-19 and underlying cardiovascular disease (CVD). Results: The majority of patients (110 or 60.4%) had previously reported cardiomyopathy, and other cardiovascular disease included earlier myocardial infarction, stroke, cardiac arrhythmias, cardiac surgery, compensated cardial disease, and acute myocardial infarction. Total of 159 (87.4%) patients received corticosteroids during treatment. Tocilizumab has been used in 16 patients; nine survived and seven died. Conclusion: Even some studies proved that it might improve clinical presentation and prevent lethal outcomes; in our study there were no significant results to confirm this thesis. Peer Review History: Received 28 September 2024; Reviewed 15 November; Accepted 21 December; Available online 15 January 2025 Academic Editor: Dr. DANIYAN Oluwatoyin Michael, Obafemi Awolowo University, ILE-IFE, Nigeria, toyinpharm@gmail.com Average Peer review marks at initial stage: 6.0/10 Average Peer review marks at publication stage: 7.5/10
The occurrence of spinal deformities during periods of rapid growth in children has been increasingly recognized as a significant issue within the broader community. This study aimed to evaluate the spinal posture during one of the most critical phases of physiological development in a specific group of preschool children. The research involved 153 preschool aged 4 to 6 years (mean age ± standard deviation: 4.6 ± 1.1 years) residing in Sarajevo. Postural assessment was conducted using the method proposed by Napoleon Wolanski (1975), which evaluates segmental relationships through the following parameters: head posture assessment (HPA), shoulder posture assessment (SPA), scapular posture assessment (SBPA), chest posture assessment (CPA), scoliotic posture evaluation (SCP), abdominal posture assessment (APA), leg posture assessment (LPA), and foot posture assessment (FPA). Deviations were categorized based on severity, assigned negative points as follows: 0 points for no deviation, 1 point for mild deviation, and 2 points for significant deviation. The associations between the eight parameters were analyzed using Spearman’s correlation coefficient (rho). The highest degree of correlation was observed between the variables of abdominal posture assessment and head posture assessment (0.536). Poor abdominal posture, often linked to weakened core muscles or imbalances in the lumbar region, can result in compensatory shifts in the head and neck to preserve balance and visual orientation.
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