We investigate models that can induce significant modifications to the couplings of first- and second-generation quarks with Higgs bosons. Specifically, we identify all simplified models featuring two vector-like quark states which can lead to substantial enhancements in these couplings. In addition, these models generate operators in Standard Model Effective Field Theory, both at tree-level and one-loop, that are constrained by electroweak precision and Higgs data. We show how to evade constraints from flavour physics and consider direct searches for vector-like quarks. Ultimately, we demonstrate that viable ultraviolet models can be found with first-generation quark Yukawa couplings enhanced by several hundred times their Standard Model value, while the Higgs couplings to charm (strange) quarks can be increased by factors of a few (few tens). Given the importance of electroweak precision data in constraining these models, we also discuss projections for future measurements at the Tera-$Z$ FCC-ee machine.

Beyond Standard Model scenarios addressing the flavor puzzle and the hierarchy problem generally predict dominant new physics couplings with fermions of the third generation. In this Letter, we explore the collider and astrophysical signatures of new light scalar and pseudoscalar particles dominantly coupled to the $\tau$-lepton. The best experimental prospects are expected at Belle II through the $e^+e^-\to\tau^+\tau^-\gamma\gamma$, $\tau^+\tau^-\gamma$, $3\gamma$, mono-$\gamma$ processes, and the $\tau$ anomalous magnetic moment. The correlated effects in these searches can unambiguously point toward the underlying new physics dynamics. Moreover, we study astrophysics bounds - especially from core-collapse supernovae and neutron star mergers - finding them particularly effective and complementary to collider bounds. We carry out this program in the well-motivated context of axion-like particles as well as generic CP-even and CP-odd particles, highlighting possible ways to discriminate among them.

We propose a unique topological portal between quantum chromodynamics (QCD) and a dark sector characterized by a global symmetry breaking, which connects three QCD to two dark pions. When gauged, it serves as the leading portal between the two sectors, providing an elegant, self-consistent scenario of light thermal inelastic dark matter. The inherent antisymmetrization leads to diminished annihilations at later times and suppressed direct detection. However, novel collider signatures offer tremendous prospects for discovery at Belle II.