Simple Summary The virus responsible for COVID-19 can affect multiple animal species, including wildlife. In this study, we tested, by commercial ELISA, blood samples from red foxes and golden jackals in Serbia for IgG anti-SARS-CoV-2 antibodies. Antibodies were detected in both species, with a seroprevalence of 13.3% in red foxes and 7.3% in golden jackals (overall seroprevalence: 10.3%). All the samples were tested in parallel by an in-house adapted ELISA. These results provide the first evidence of SARS-CoV-2 exposure in wild canids in Serbia. Monitoring pathogens in wildlife improves our understanding of disease ecology and supports early recognition of potential zoonotic risks.
Abstract Congenital intrinsic obstruction at or near the duodenojejunal junction is exceptionally rare and most commonly results from incomplete embryonic recanalization, leading to the formation of a mucosal web. We report a 7-day-old term male neonate (birth weight 3350 g) who presented with persistent feeding intolerance and intermittent bilious vomiting since birth. Abdominal radiography showed marked dilation of the stomach and duodenum with distal bowel gas. An upper gastrointestinal contrast study revealed a conical narrowing at the duodenojejunal junction. Surgical exploration revealed a mucosal web located immediately distal to the duodenojejunal junction. Given the marked luminal disparity, simple web excision was deemed inadequate, and segmental resection with primary end-to-end jejunojejunal anastomosis was performed. Postoperative recovery was uneventful. Proximal jejunal webs near the duodenojejunal junction are rare but surgically correctable causes of neonatal bilious vomiting and should be considered in the differential diagnosis.
In this paper, the dynamic analysis of a vibro-impact system with ideal excitation and various friction models is performed. A physical model of an oscillating mechanical system with possible impact occurrence is presented and the corresponding mathematical model is derived by using Lagrange’s equations of motion. To describe interaction between impact element and environment, three different friction models are considered: Coulomb, viscous and Coulomb-Stribeck model. Newton’s impact law with a coefficient of restitution is employed to describe relationship between pre-impact and post-impact velocities. The dynamic behavior of the vibro-impact system under the ideal excitation, where the system does not influence the excitation source, is investigated for each friction model by numerically solving the governing equations. The results of numerical analysis are presented through amplitude-frequency diagrams, displacement-time responses and phase portraits. The main objective is to determine the influence of different friction models on amplitude-frequency diagrams, particularly on the regions exhibiting impact and non-impact behavior. For parameter regions with multiple coexisting solutions, basins of attraction are constructed to illustrate the dependence of the system regime on initial conditions.
ABSTRACT Indoor spaces contain diverse microbial communities that shape human health. These microorganisms are particularly relevant to respiratory diseases, including asthma and allergies. Despite growing recognition of the importance of indoor microbial exposures, research in this field is slowed by differences in methods. These inconsistencies make it difficult to compare results and draw conclusions. This systematic review analyses 106 studies published between 2000 and 2025 that investigated indoor microbiomes in dust, air, and other matrices across homes, schools, and other built environments. We assessed sampling strategies, DNA extraction protocols, sequencing technologies, and bioinformatic pipelines, identifying trends, inconsistencies, and areas requiring harmonisation. Passive sampling, particularly dust collection, was the most common approach, while Illumina‐based 16S rRNA and ITS amplicon sequencing dominated molecular analyses. However, variations in targeted gene regions, extraction kits, and analytical tools limited cross‐study comparability. Ecological findings revealed consistent detection of bacterial taxa such as Staphylococcus, Streptococcus, and Corynebacterium, and fungal taxa including Cladosporium, Aspergillus, and Penicillium, with diversity shaped by building characteristics, ventilation, humidity, occupancy, and presence of pets. This review highlights the need for standardised protocols in indoor microbiome research to facilitate reproducibility, enable meta‐analyses, and inform health‐related guidelines for indoor environments.
Introduction: Cognitive impairment is the most common neurological disorder associated with brain tumors, which leads to linguistic communication damage. Anxiety and depression are among the most prevalent psychiatric comorbidities in this population. Objectives: To determine the level of cognitive functioning, anxiety, and depression in patients with intracranial tumors with and without aphasia. Subjects and methods: A prospective study was conducted on 91 patients with verified brain tumors which were hospitalized at the Clinic for Neurosurgery for one year period. The patients were assessed with Mini Mental State Examination, Beck’s depression inventory, and Beck’s anxiety inventory. The type and severity of aphasia were determined by the Boston Aphasia Test. Results: The highest number of patients, a total of 31 (37.3%), had moderate anxiety disorder. 30 patients (36.1%) had shown symptoms of moderate depression, and 33 (39.7%) had shown mild and moderate cognitive dysfunction. Conclusion: Anxiety, depression, and cognitive dysfunction were significantly more pronounced in subjects with aphasia.
To evaluate clinical characteristics and outcomes of urgent bronchoscopies due to foreign body aspiration (FBA), we analyzed cases from January 1954 to December 2021. The study included children up to 14 years of age who underwent emergency bronchoscopy on suspicion of a foreign body in the lower respiratory tract. Each patient was assessed for age, sex, nature and location of the foreign body, bronchoscopy findings, complications, and airway involvement. A total of 889 children underwent urgent bronchoscopy over 67 years. Most cases (66.7%) occurred within the first three years of life, and 10.6% involved children under one year of age. Recently, a marked decrease in positive findings in infants has been observed. Boys represented 62.5% of cases. Organic foreign bodies, predominantly pumpkin seeds, were most common. The right bronchus was the predominant location (51%). In the most recent period, multiple-location foreign bodies became more frequent. Both the annual number of bronchoscopies and the proportion of positive findings have declined. During the COVID-19 pandemic, suspicion of FBA and the number of bronchoscopies significantly decreased.
Hydrophobic eutectic solvent systems (ESSs) were prepared and characterized using temperature-dependent thermophysical and transport property measurements, supported by thermal analysis. The investigated systems comprise terpene-based mixtures, menthol:octanoic acid (1:2) and menthol:decanoic acid (1:1), and thymol-based mixtures, thymol:butanol (1:1), thymol:hexanol (1:1), thymol:octanoic acid (1:1), and thymol:oleic acid (1:1), as well as salt-containing ESSs based on tetrabutylphosphonium bromide (TBPBr), TBPBr:octanoic acid (1:1), and TBPBr:lauric acid (1:1). Density, dynamic viscosity, and electrical conductivity were measured at atmospheric pressure (p = 0.1 MPa) over 293.15–313.15 K. From density data, molar volumes and isobaric thermal expansion coefficients were calculated. The temperature dependence of viscosity was correlated with both Arrhenius and Vogel–Fulcher–Tammann equations. Conductivity results were used to compute molar conductivities, and the coupled conductivity–viscosity behavior was assessed via Walden analysis to quantify deviations from ideal electrolyte behavior and estimate ionicity. Thermal behavior and stability were evaluated by differential scanning calorimetry (DSC) and simultaneous thermogravimetric analysis (TG/DSC). The resulting dataset enables a consistent comparison of volumetric, flow, and ion transport descriptors across fully molecular terpene-based mixtures and TBPBr-containing systems. Overall, the combined transport descriptors, including Walden analysis, provide a practical framework for distinguishing molecular from salt-containing hydrophobic ESS families and support formulation selection for temperature-dependent applications, particularly in biphasic extraction processes.
The search for new anticancer agents with improved efficacy and reduced toxicity has intensified interest in metal-based compounds. In this study, two novel palladium(II) complexes, synthesized from Schiff base ligands derived from 5-chloro-salicylaldehyde and p-hydroxybenzylamine or tyramine, were chemically characterized and biologically evaluated. Both complexes exhibited significant cytotoxic activity against the MCF-7 breast cancer cell line in a dose- and time-dependent manner, with Pd2 showing slightly higher potency. Morphological analysis of treated cells indicated that apoptosis is the predominant mechanism of cell death. To gain deeper insight into the potential mechanisms underlying the observed anticancer activity, several biologically relevant targets were investigated. Enzyme kinetics revealed that the complexes act as uncompetitive inhibitors of liver catalase, suggesting a possible role in the induction of oxidative stress. Fluorescence studies demonstrated that Pd2 interacts with CT-DNA through combined intercalative and minor groove binding modes and exhibits significant binding affinity toward human serum albumin, predominantly at Sudlow’s site I. Molecular docking analysis further supported favorable interactions with catalase, estrogen receptor α, and B-form DNA, providing structural insight into the experimentally observed biological effects. Overall, the study explores multiple potential mechanisms of anticancer action, underscoring the promising therapeutic potential of these palladium(II) complexes, while antitumor activity has been initially assessed using a MCF-7 cell line as a preliminary model.
Autori u radu pišu o političkoj situaciji u Banja Luci od 1990. do kraja 1992. godine. To je period od održavanja prvih višestranačkih izbora do perioda intenzivne kampanje protjerivanja i masovnih zločina u Banja Luci. Osim osvrta na rezultate izbora 1990., demografska slika opštine prema popisu stanovništva u Bosni i Hercegovini 1991. godine imala je veoma važnu ulogu u odnosu prema brojčano manjinskim narodima. U Banja Luci i cijeloj Bosanskoj krajini već su 1991. godine bile vidljive refleksije agresije Jugoslovenske narodne armije (JNA) na Hrvatsku, što je dovelo do zaoštravanja međunacionalnih odnosa. Izbijanjem agresije na Republiku Bosnu i Hercegovinu 1992. godine počinjeni su masovni zločini nad banjalučkim civilima bošnjačke i hrvatske nacionalnosti od strane Vojske Srpske Republike BiH (VSrRBiH) / Vojske Republike Srpske (VRS) i pripadnika policijskih struktura pri Ministarstvu unutrašnjih poslova (MUP) SrRBiH/RS. Terorisanje, zločini, prisilno odvođenje u logore i druga mjesta zatočenja te progon nad pripadnicima ova dva naroda nastavljeni su i nakon 1992. godine o čemu govore relevantni dokumenti i svjedočenja očevidaca.
Generative artificial intelligence (AI) occupies a dominant transformational position in a wide range of fields, including education, business, law, medicine, rehabilitation – among others. Despite the controversies regarding the use and abuse of this technology, it is possible for professionals, especially those in education, to reap its benefits for instruction, research, and administrative endeavors. Keeping in mind the ethical concerns and the current limitations of the system, AI can provide substantial assistance to, for example, teachers, students, and scholars. Setting aside fears of this technology, teachers can save time and become more efficient and productive with their administrative and instructional tasks. Teachers can also use AI to improve the academic, communication, and social skills of students, including—and especially--students in special education programs. Students can learn to use AI independently; in fact, AI can help students to become autonomous and critical seekers of knowledge. After highlighting some challenges of using AI, the present manuscript discusses a few benefits of AI for children and adolescence who are d/Deaf and hard of hearing (d/Dhh). The manuscript also contains recommendations for teacher education and future research endeavors.
This paper aims to systematically present existing research on cognitive and executive functions, speech and auditory perception, language, literacy, and academic development, and cross-modal reorganization in children with CIs. The methodology included a systematic search of databases (PubMed, Scopus, Web of Science) using keywords related to cognition and CIs. After eliminating duplicates and applying inclusion criteria, an analysis was conducted of relevant references published from 2015 to the present, which were analyzed both in tables and narratively. Research confirms that the cognitive development of children with CIs depends on auditory input and the brain’s ability to integrate information from different sensory modalities. Multisensory and interactive approaches to rehabilitation have the potential to enhance cognitive development and should be further researched and applied in practice.
U ovom radu analizira se odnos socijalne politike prema civilnim žrtvama rata i njihova međusobna korelacija u Bosni i Hercegovini. Krajnji cilj je doći do odgovora na pitanja kako odgovoriti potrebama civilnih žrtava rata kroz kvalitetnu socijalnu politiku u Bosni i Hercegovini. U ostvarivanju socijalne pravde, socijalnih prava, smanjivanju društvene nejednakosti i općoj humanizaciji društva u Bosni i Hercegovini posebnu ulogu ima upravo socijalna politika. S tim u vezi primjenu socijalnih politika u području brige i zaštite civilnih žrtava rata sve više pažnje usmjeravaju na deinstitucionalizaciju i tako nastoje da trendovi u brizi o civilnim žrtvama rata idu prema zbrinjavanju ne na državnom nivou, nego na nivou lokalne zajednice. Ono što bi moglo biti jedno od rješenja ili državnih strateških pravaca jeste razvijanje različitih modela podrške, uz podršku njima najbližih osoba, odnosno podrška primarne socijalne mreže uz podršku države. Činjenica je da se naše društvo mora suočiti sa izazovom kreiranja sistema koji će biti prilagođen i u skladu s potrebama kategorije civilnih žrtava rata. Važan preduslov za poboljšanje statusa i brige o civilnim žrtvama rata jeste kroz primjenu kvalitetne i zakonom utvrđene socijalne politike. Odnos socijalne politike prema kategoriji civilnih žrtava rata je vrlo prisan, samom činjenicom jer se ona bavi raznim društvenim segmentima, a civilne žrtve rata su upravo jedna od najugroženijih društvenih kategorija čija ljudska, socijalna i druga prava, bi se trebala početi primjenjivati onako kako to nalažu i međunarodne konvencije koje su sastavni dio socijalne politike, a ne biti samo mrtvo slovo na papiru.
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