Health care is the most important activity and human kind is dealing with its organization for centuries. Public health policies and functional health care systems have as their primary objectives the preservation and improvement of public health. Problems of intensive aging of the population, continuous growth of health spending, ensuring sustainable financing of health systems and efficient use of resources are present in all world health systems. Health care system reforms have become a global phenomenon for the last twenty years of the last century. The goal of this review paper is to point out the importance and need for timely modifications of the strategy of the health care optimization plan in Serbia by 2035, so that the health care system of Serbia would be ready to respond to potential global health crises in the future. The Plan for optimizing the health care institutions network by 2035 as a key document of the Master Plan will be briefly presented with an analysis of key parameters of health care effectiveness and above all improvement of the implementation of basic principles of health care - uniformity and availability of health services on the territory of Republic of Serbia. In order to present future key changes in the health system, it is necessary to take into account the current situation, as well as the potential consequences of the global pandemic of COVID-19 virus on health systems. Databases were used for analysis: WHO, OECD, World Bank Reports. The tendency of increasing the share of health care costs in GDP, with the problems of efficient use of health care resources, is becoming the most important reason for reforming health insurance and health care in almost all countries in the world. Numerous researches of eminent experts in the field of economy and finance indicate that the introduction of compulsory health insurance with a clearly defined package of health conditions is the most rational choice in the implementation of the World Health Organization project: "Health for all in the 21st century". A health system could be said to be effective if it provides health care of maximum quality in terms of medical outcome, with minimal costs in relation to the allocated funds. Health care systems around the world today face very similar problems, and the COVID-19 pandemic has shown how "vulnerable" it is not only the health system but all of humanity when faced with such challenges.

. Healthcare professionals have a key role to play in the introduction, application and use of technology in clinical practice. The lack of technical expertise and technological understanding poses a challenge to the quality of health services and probably to the safety, dignity and quality of life of patients. Experience so far speaks of computer literacy, which is the basis of the implementation of the health information system and varies according to gender, age and years of work experience. Determine whether computer literacy depends on gender, age, and years of service. The research was conducted according to the type of cross-sectional study, in the population of health workers employed at the Health Center in Jagodina and the General Hospital in Ćuprija. Yesterday’ s sample consisted of 142 respondents. A structured questionnaire was used for data collection, statistical data processing was performed with the computer support of the statistical package for social sciences IBM SPSS Statistics, Version 23 (Statistical Package for Social Sciences). Analysis of variance was used from statistical tests. Results. Sample composed of 78.2% of respondents and 27.2% of respondents; in both groups of respondents, the average achievement on the literacy scale is around 17 points. Age 40 and over is 59%; the first two groups (less than 30 years of age and 30 to 39 years of age) are statistically significantly different from the oldest groups of respondents (F = 4.949, p = 0.003, df = 3). The largest percentage of respondents have a work experience of 10-29 years; younger respondents have more knowledge of computers (F = 7.239, p = 0.000, df = 3). Computer literacy depends on age and years of service.

Introduction Infective endocarditis is relatively rare in pediatric population, but can result in significant morbidity and mortality. Children with bicuspid aortic valve are at higher risk of developing infective endocarditis as compared to general population. Our objective is to emphasize the importance of rapid diagnosis and proper treatment of infective endocarditis in patients with bicuspid aortic valve with aim to prevent serious adverse events. Case outline We report a case of a 13-year-old girl with newly diagnosed bicuspid aortic valve who developed infective endocarditis with severe complications and underwent cardiac surgery. Recurrent fever and anemia, as well as cardiac murmur were present for six months prior to diagnosing infective endocarditis. During the course of illness, only one of many blood cultures taken was positive for Streptococcus sanguinis. Conclusion Patients with bicuspid aortic valve require careful evaluation for infective endocarditis, especially if recurrent fever associated with anemia is present. Delayed diagnosis of infective endocarditis is associated with serious complications.

Introduction. The human voice is an important characteristic that enables the distinction of human from other living beings. Otherwise, it represents a picture of a person΄s personality, his health, mental and emotional state. The research aims are to determine the voice characteristics of vocal professionals with diagnosed vocal cord nodules by subjective voice assessment and objective voice measurement before and after vocal rehabilitation. Methods. This study has involved 25 examinees, aged 23 to 56. The subjective voice assessment was conducted with the Voice Handicap Index - VHI questionnaire and the objective voice measurement by a computerized laboratory for voice analysis ''Kay Elemetrics''. The obtained data were processed using descriptive and analytical statistics. Results. Before the vocal rehabilitation and the subjective and objective voice measurements, the examinees had greater psychosocial difficulties associated with their voice quality. After two months of vocal rehabilitation, there has been a significant improvement in the voice of all subjects on the VHI scale. A statistically significant and highly statistically significant improvement have been noticed in six out of seven analyzed parameters of vocal A, by the objective measurement of voice. Namely, the obtained values - the percentage of jitter Jitt (%), the percentage of shimmer Shim (%), the relative average perturbation value RAP (%) and the coefficient of fundamental frequency variation - vFo were highly statistically significant (p < 0.01). The VTI - voice turbulence index and the SPI - soft phonation index also improved, the observed difference was statistically significant (p < 0.05), while the observed difference in the FTRI parameter was not statistically significant (p > 0.05). Conclusion. Vocal rehabilitation has influenced the improvement of the voice quality, which means that the results obtained by objective voice measurements were more in accordance with the results of the subjective voice assessment.

According to the World Health Organization (WHO) and the International Society for Hypertension, elevated blood pressure is defined as the blood pressure the readings of which consistently range ≥140 mmHg systolic and/or 90 mmHg diastolic. Having in mind the fact that hypertension is one of the leading risk factors for cardiovasluar disease, kidney failure and premature mortality, it is clear that preventive measures should be imposed before the diagnosis is established. The main nutritional measures used in preventing hypertension are: weight loss, Dietary Approaches to Stop Hypertension (DASH diet), reducing salt and alcohol intake and increasing potassium intake. The aim of this paper was to show the preventive effect of the DASH diet on hypertension onset in normotensive patients as well as to highlight that the diet is an integral part of hypertension treatment, in addition to the use of drug therapy for hypertensive patients.

Background/Aim: Antibiotic use and resistance represent a growing public health issue, with a specific risk of uncontrolled use of antibiotics in children. The aim of the study was to examine differences in parental knowledge, attitudes and practices about antibiotic use in children between urban and rural areas of the Republic of Srpska. Methods: A cross-sectional study was conducted among 1459 parents of children under 6 years of age, out of which 1201 (82.3 %) lived in urban areas while 258 (17.7 %) lived in rural areas. The research is conducted among parents who brought their children to the selected primary healthcare centres and among parents of children in preschool institutions. Results: The majority of respondents (98.4 %) state that doctors are their main source of information. Only 61.2 % of respondents precisely know which drug is an antibiotic when offered different drugs and respondents from rural areas (54.3 %) more often (p = 0.012) gave more accurate answers when compared to respondents from urban areas (37.3 %). Among parents, 86 % agree with the statement that improper use of antibiotics reduces their effectiveness and leads to bacterial resistance, regardless of groups. More than a half of respondents (52.4 %) do not think that children with flu or common cold symptoms recover faster when they receive antibiotics, significantly more respondents from urban areas (p = 0.001). Respondents from rural areas significantly more often believe that antibiotics can produce harmful effects compared to respondents from urban areas (p = 0.049). Respondents from rural areas significantly more often think that antibiotic use can prevent complications caused by inflammation of the upper respiratory tract (p = 0.006). Parents from rural areas give their children antibiotics without a paediatrician's recommendation significantly more often (4.3 %) compared to respondents from urban areas (0.6 %) (p < 0.001). Conclusion: There are differences in parental knowledge, attitudes and practices regarding antibiotic use and antimicrobial resistance among parents in rural and urban areas. There is need for additional education of parents and for greater engagement of paediatricians in providing guidance and explanations regarding the use of antibiotics.

The aim of this study was to compare the yield and fruit quality characteristics of raspberry (Rubus idaeus L.) cultivar ʽMeeker' grown in organic and conventional cultivation systems. The total soluble solids, titratable acidity, ascorbic acid content, total phenolic and flavonoid contents and total antioxidant capacity of raspberry fruits were assessed. The analyses showed that raspberry yields per cane were significantly higher in the conventional cultivation system. In contrast, fruits from organic farming had higher antioxidant levels. The findings of this study indicated that organic farming in the study region increased raspberry quality, but decreased yield, as compared to conventional farming.

The effect of the partial replacement of natural filler by ground waste sulfur originating from the oil refining process on the fresh and hardened properties of self-compacting concrete was investigated. Properties investigated were slump flow, V-funnel, L-box, and sieve segregation of fresh concrete mixes; compressive, flexural, and bond (pull off) strengths, dynamic modulus of elasticity, ultrasonic pulse velocity, dynamic Poisson’s ratio, specific electrical resistance, density, and microstructure of hardened concrete. Results showed a slight decline in compressive, flexural, and bond strengths and dynamic elasticity modulus with increased addition of sulfur. Specific electrical resistance and density were higher for samples containing sulfur. Also, scanning electron microscopy indicated a slight porosity increase in the samples containing sulfur. Having in mind that, in the case of waste valorization in concrete, all properties of self-placing concrete should remain within acceptable levels or improve, this study proved that mixtures containing ground sulfur as a partial replacement for filler could be used for structural applications.

Accounting monitoring stocks of raw materials and supplies plays an important role in the business of every major company. Since inventories are one of the most expensive types of company assets, accounting for more than 50% of total invested capital, optimal inventory management should be an integral part of every company's business. In order to get complete results, this paper applies the ABC method, XYZ method, as well as the cross ABC XYZ method. The goal is to reduce costs of keeping the inventory as much as possible, while maintaining a level of service customers requires. The process of assortment planning, ordering and inventory management in the construction material warehouse is analyzed. The importance of monitoring inventory movements in order to achieve optimal amount of inventory, as well as the obtained results and guidelines for future operations is presented.

Different qualitative and quantitative changes in platelets are involved in the pathophysiological processes in inflammatory bowel diseases (IBD): ulcerative colitis (UC) and Crohn's disease (CD). The aim of the study was to determine the diagnostic accuracy of Platelet mass Index (PMI) and other platelet parameters in assessment disease activity in patients with UC and CD. A cross-sectional, observational study consisted of 60 IBD patients (30 UC and 30 CD) and 30 healthy subjects (Control group). Patients were grouped according to disease activity into active and inactive (remission). Platelet count (PLC), Plateletcrit (PCT), Mean Platelet Volume (MPV), Platelet Distribution Width (PDW) and PMI were determined for all study participants. Receiver operating characteristic (ROC) curve and their corresponding areas under the curve (AUC) were used to determine diagnostic accuracy. Although PLC had the highest AUC (0.756) compared to PCT (AUC: 0.731), PDW (AUC: 0.722) and PMI (AUC: 0.724), they all had fair diagnostic accuracy in distinguishing active and inactive UC patients. Discriminatory accuracy of PLC was excellent (AUC: 0.909), PCT and PMI good to excellent (AUC: 0.809 and AUC: 0.893, respectively) and PDW fair (AUC: 0.789) in classifying CD patients as active and inactive. Platelet parameters are simple, routinely available biomarkers more useful for assessing disease activity for patients with CD than for patients with UC. Our results indicate, for the first time, that PMI may serve as a novel and simple marker in identifying whether IBD patients are in the active or inactive phase of the disease.

Stainless steel X8CrNiS18-9 (standard EN 10088-3: 2005) is the most commonly used austenitic stainless steel due to its good machinability. This steel has high mechanical and working properties thanks to complex alloying, primarily with the elements such as chromium and nickel. The content of sulfur present in the steel from 0.15 to 0.35% improves machinability. Microalloying with tellurium and zirconium (individually and in combination) in most cases leads to improved properties of this stainless steel, compared to melt without alloying additives, e.g. the melt microalloyed with tellurium and especially melt microalloyed with zirconium and tellurium has significantly better machinability compared to the melt without alloying elements. The addition of sulfur, which is the cheapest available additive for free machining, will impair not only the transverse strength and toughness but also the corrosion resistance. However, while sulfur improves machinability at the same time decreases the mechanical properties, particularly toughness. This work aims to test the machinability, corrosion resistance, and mechanical properties of the mentioned steel, as well as the chemical composition of non-metallic inclusions.

Over the last decades, globalization has brought many positive effects for the companies operating overseas including exposures to new cultures and belief systems. However, such international exposure has also brought certain problems in terms of cultural differences from different markets. Expatriates (international managers) when running international operations and managing foreign teams come across many obstacles caused by differences in national cultural systems, therefore it is important to have a good understanding how cultures differ from each other and what is the best way to approach each one of them in the right way. Therefore, the aim of this paper is to determine how intercultural differences affect human resource management in an international context and how expatriates should adapt their leadership styles to the requirements of local markets. Moreover, the paper elaborates on differences between domestic and international management styles and on the differences between leadership styles across different regions.

Illegal waste landfills are a current problem facing a large number of countries. In order to control and better manage illegal landfills, it is necessary to know the updated locations and contents of illegal landfills. Remote sensing methods have proven to be extremely effective in the automated detection of potential sites of illegal landfills. This paper focuses on the experimental testing of different values of the segmentation scale parameter of the Pleiades 1B satellite image in the function of detecting illegal landfills in the area of Novo Sarajevo municipality. In this case, the optimal value of the scale parameter is considered to be the value that gives the highest accuracy of classification and whose segments best correspond to the real situation on the ground.

Little is known about the presence of methicillin-resistant Staphylococcus aureus (MRSA) in a canary bird (Serinus canarius domesticus). Although MRSA in a canary bird was previously reported, to the best of our knowledge, this is the first full description of the isolation and antibiotic resistance pattern of MRSA in this pet bird. A swab was taken from the nonhealing wound on the lateral thigh of a four-year-old, caged, housed alone, male canary bird. After the identification of Staphylococcus aureus, the antibiotic susceptibility profile of the isolate was obtained by the disk diffusion test. According to the resistance to Oxacillin and Cefoxitin, the isolate was identified as MRSA. The mecA gene was confirmed by PCR. The bird was treated by offering drinking water medicated with an injectable enrofloxacin formulation at 200 mg/L over 10 days period. Two weeks after therapy, intensive contraction of the wound was observed with a reduction in size. A week later, the complete epithelization of the wound defect was verified. In this study, we could not confirm the source of infection in a canary bird, but we believe that transmission was from wild birds when the cage was putting out in order to allow the bird to sunbathe or more likely via contact with the owner. The results of this study underline the necessity for further investigations on the epidemiological role of canary birds as potential reservoirs of MRSA.