Cleaner production is certainly a challenge of our everyday life, and a lot of effort and energy is required to achieve it. This paper has created a model of five strategies for cleaner production in Libyan industry, which have been evaluated on the basis of eight criteria. In order to determine the significance of the criteria, a novel interval rough SWARA (step-wise weight assessment ratio analysis) method has been developed, which takes into account the preferences of decision-makers (DMs) by applying interval rough numbers. A novel interval rough ARAS (additive ratio assessment) method has been developed for the evaluation and selection of the most favorable strategy for cleaner production. The integration of the developed methods has yielded results showing that the first strategy, launching awareness-raising campaigns to publicize these policies, represents the most realistic and best current solution to achieve cleaner production in Libyan industry. A comparative analysis with some existing interval rough methodologies has been presented to verify the superiority of the proposed model. In addition, in a sensitivity analysis, the weight of the most significant criterion has been changed.

ABSTRACT This paper aims to extend an understanding of the cognitive drivers, namely excitement and sincerity, of brand love and store brand loyalty. It also examines the mediating role of brand love in the relationship between excitement and sincerity, and store brand loyalty. Field research, complemented with mall intercept method, was conducted within eight retail facilities of the biggest trade center in a developing country setting. A total of 450 useful questionnaires were collected and hypotheses were tested using structural equation modeling. The results show that excitement and sincerity, as cognitive drivers, are important predictors of brand love. It has been also proved that brand love fully mediates the relationship between excitement and sincerity, and store brand loyalty. The paper contributes to the retailing and brand–customer relationship literature by revealing new predictors of brand love and store brand loyalty, and enriching the existing, faintly researched brand love mediation body of knowledge in the developing country context. It also highlights the features relevant for a better retail store positioning toward creating store brand loyalty. It is expected that the findings can make changes in store brand positioning, as appropriately positioned store brands could lead to emotional connections and loyalty. More specifically, the findings of the paper highlight which store brand cognitive elements could lead to consumer involvement in the buying process.

The aim of this study was to assess awareness among the students of the Faculty of Dentistry of the University of Sarajevo of the occupational health risks associated with dental profession. The research was conducted among the dental students of all years of study at the Faculty of Dentistry of the University of Sarajevo, by using a tailor-made survey questionnaire. The questionnaire was completed by 446 students. Results: 92% of students believe that dentistry is a profession that involves a high level of risk for the outbreak of occupational diseases. Students believe that practicing dentistry can most often lead to various infections (70%) and vision impairments (64%), and that the most common potential causes of occupational diseases are poor positioning and incorrect body posture during work (88%) and infections (78%). When asked whether the occupational diseases among dentists are preventable, 89% of students gave an affirmative answer, and pointed to the requirement to use Personal Protection Equipment – PPE (94%) as the most important measure for the prevention of occupational diseases among dentists. The results of the survey show that the students of dentistry at the Faculty of Dentistry of the University of Sarajevo have reached a certain level of awareness of the health risks that are associated with their future profession. The students have taken a largely identical view that dentistry is a profession that involves a high level of risk for the development of occupational diseases.

O presente artigo tem como objetivo denunciar o direito enquanto um campo masculinista, e como essa lógica se reproduz por meio de um ensino jurídico que se estrutura por um tipo de raciocínio que apaga as práticas discursivas e relacionais das mulheres. Em um primeiro momento, por meio dos ensinamentos de Duncan Kennedy (1984), do Critical Legal Studies (CLS), faz-se uma descrição da forma como o ensino jurídico se opera, em especial, ao denunciar o direito como uma prática engajada sócio, política e economicamente, que se reproduz por intermédio de um sistema hierarquizado dessas categorias expostas. Em seguida, questiona-se se essa pirâmide hierárquica não pressupõe, igualmente, uma assimetria de gênero, que se apreende pela configuração do ensino jurídico como uma prática que reproduz paradigmas falocêntricos, como a argumentação e um repúdio pelo particular, pela experiência e pelo contextual. Nesse ponto, debate-se com fundamento nos escritos da autora estadunidense Carrie Menkel-Meadow (1988). Ao final, realiza-se um exercício imaginativo ao propor possíveis mudanças nesse modelo de ensino hierárquico e marcado pelo olhar masculino.

The aim of this study was to examine the content of total soluble substance (TSS), total acidity (TA), pH, ascorbic acid content (vitamin C) and total phenols in fresh strawberries, as well as in strawberries stored for 10 days by freezing. Chemical characterization of fresh and frozen strawberries was done on four different varieties: Clery, Maya, Asia, Joly grown in the area of Čelić, Bosnia and Herzegovina. The obtained results showed that frozen strawberries have slightly lower values of TSS, pH, vitamin C, while the content of TA and total phenols was slightly higher in frozen strawberries than in fresh ones, which can be attributed to increasing acidity.

The study was conducted on a sample of 70 deaf children, chronologically aged from 10 to 18 years. Letters of deaf respondents on topics of their choice were used as a measurement instrument. The goals of the research are: To examine the homogeneity of variance of content understanding of written form of expression based on measurements of applied language constructions and content within language discourse, and to determine the statistical significance of content understanding of written form of expression using language constructions within language discourse. The second goal of the study was to examine the connection of language constructions in the applied measurement space of the number of used written expressions in the content understanding of written communication, and to determine the statistical significance of the connection of language constructions in the number of used written expressions in content understanding of written communication. The results of the research showed that the deaf population is characteristic and homogeneous in the way, style of writing and content understanding of the written text observed through linguistic discourse in written dialogue. In the written form of exchange of communication content, a significant degree of communication competence has been achieved, or the comprehensibility of the written form of expression in terms of content understanding. Deaf persons achieve very modest linguistic competence. The reduced ability of deaf children to achieve linguistic competence is reflected through the simplicity of statements in the substantive sense of preferring statements, as one of the characteristics of the linguistic competence of the deaf population.

Noninvasive prenatal testing (NIPT) is the most recent modality widely used in prenatal diagnostics. Commercially available NIPT has high sensitivity and specificity for the common fetal chromosomal aneuploidies. As future advancements in NIPT sequencing technology are becoming promising and more reliable, the ability to detect beyond aneuploidies and to expand detection of submicroscopic genomic alterations, as well as single-gene disorders might become possible. Here we present a case of a 34-year-old pregnant woman, G2P1, who had NIPT screening which detected a terminal microduplication of 10.34 Mb on the long arm of chromosome 15 (15q26.1q26.3). Subsequent prenatal diagnostic testing including karyotype, microarray and fluorescence in situ hybridization (FISH) analyses were performed. Microarray testing confirmed and particularized a copy number gain of 10.66 Mb of the distal end of the long arm of chromosome 15. The G-banding cytogenetic studies yielded results consistent with unbalanced translocation between chromosome 15 and 18. To further characterize the abnormality involving the long arm of chromosome 18 and to map the genomic location of the duplicated 15q more precisely, FISH analysis using specific sub-telomeric probes was performed. FISH analysis confirmed that the extra duplicated segment of chromosome 15 is translocated onto the distal end of the long arm of chromosome 18 at band 18q23. Parental karyotype and FISH studies were performed to see if this unbalanced rearrangement was inherited from a healthy balanced translocation carrier versus being a de novo finding. Parental chromosomal analysis provided no evidence of a rearrangement between chromosome 15 and chromosome 18. The final fetal karyotype was reported as 46,XX,der(18)t(15;18)(q26.2;q23)dn. In this case study, the microduplication of fetal chromosome 15q26.1q26.3 was accurately detected using NIPT. Our results suggest that further refinements in NIPT have the potential to evolve to a powerful and efficient screening method, which might be used to detect a broad range of chromosomal imbalances. Since microduplications and microdeletions are a potential reportable result with NIPT, this must be included in pre-test counseling. Prenatal diagnostic testing of such findings is strongly recommended.

Background: The purpose of this study was to compare home and office BP in the adjustment of antihypertensive treatment. Methods: This study was an open, prospective, noninterventional, multicenter clinical trial that occurred between July 2019 and February 2020, in 34 cities in the territory of the Republic of Serbia, which monitored 1581 participants for 6 months. Depending on the used blood pressure monitoring method used, all patients were divided into control (office BP monitoring) and experimental (home BP telemonitoring) groups. We collected anamnestic data and data about systolic blood pressure (SP), in mmHg, diastolic blood pressure (DP), in mmHg, and heart rate (HR), in beats/minute, from all patients. Results: SP values were significantly different at baseline, and at the second, third, and fourth visits between the two tested groups. Home and office BP decreased significantly (p < 0.000) during the 6-month follow-up. We observed a statistically significant influence of the presence of diabetes mellitus and dyslipidemia on the dynamics of differences between SP monitoring values. Conclusions: Our study suggests that novel technologies in BP monitoring can be excellent alternatives for BP assessment in hypertensive patients with other cardiovascular risk factors such as diabetes and dyslipidemia.

As forests in Bosnia and Herzegovina cover 2,904,600 ha or 56.7 % of its total area, and since the meteorological data analysis for the period 1961–2014 shows that the mean annual temperature maintains a continuous rise, сlose attention should be paid to these fragile ecosystems. It is important to note that one of the most economically valuable species for forestry in Bosnia and Herzegovina, Norway spruce, is particularly endangered due to its very low drought resistance and spread of various diseases. Comparing the last climate sequence (1991–2019) with the previous one (1961–1990) we found that the spruce-inhabited areas showed an average increase in the values of the Forest Aridity Index of 0.929. As for the Ellenberg’s climate quotient, it is noticeable that climate change is not as strong as in the case of the Forest Aridity Index. Based on projections for the mid- (2041–2070) and late-century (2071–2100) under the RCP 4.5, there will be no change that is likely to significantly affect the distribution of spruce. The predicted rates of decline and altitudinal shifts of favorable habitats are negligible. On the contrary, projections under the RCP 8.5 predict a significant reduction of suitable habitats, both for the existing range of Norway spruce and the entire territory of Bosnia and Herzegovina. Particularly, late-century projection under the RCP 8.5 predicts an almost complete reduction of suitable habitats, while small areas of suitable habitats at higher elevations will remain intact.

Background: IDegLira( fixed combination of GLP 1 receptor agonist and insulin) has been shown to be effective in improving the glucoregulation in patients previously treated with oral therapy as well as individual components, GLP-1 receptor agonist or basal insulin. Objective: The aim of this study is to examine the parameters of metabolic control in patients treated with IDegLira who were previously treated with premix insulin in several daily doses and to compare them with patients whose premix insulin dose was increased. Methods: The study included 100 patients who had been previously treated with two or three daily doses of premix insulin. Half of the patients were switched to IdegLira( group I), and half (group II) had their insulin dose increased according to the clinical assessment of the physician. Fasting glucose, 2h postprandial glucose, HbA1c, BMI and insulin dose were determined at baseline and at follow-up after 6 months. Results: Patients treated with IDegLira compared to patients whose insulin dose was increased achieved significantly lower fasting glucose (p <0.001), postprandial glucose (p <0.001), HbA1c (p <0.001), BMI (p <0.001) with a significantly lower insulin dose (p <0.001). Comparison of the same parameters within the groups of patients at the beginning and after 6 months showed that patients who were switched from insulin premix to IDegLira achieved significantly lower fasting blood glucose (p <0.001), postprandial glucose (p <0.001), HbA1c (p < 0.001), BMI (p <0.001) with significantly lower insulin dose within the fixed combination (p <0.001). Patients with gradually increased insulin dose achieved significant reduction in fasting glucose (p = 0.021) and postprandial glucose (p = 0.036),but with a significantly higher insulin dose (p = 0.005). There was also a slight increase in BMI that was not statistically significant (p = 0.267). Conclusion: The obtained data suggest that switching patients from a complex insulin regimen to a fixed combination of basal insulin and GLP 1 receptor agonist in comparison to increases in insulin dose results in a significant improvement in fasting glucose, postprandial glucose, HbA1c, and BMI. The results were achieved with a significantly lower daily insulin dose.

Extended Abstract Phosphonates possess a great potential for the therapy of bone tumours due to their inhibitory potential for osteoclasts. The delivery of phosphonates via cellulose nanocrystals (CNCs) seems a promising approach for their increased efficacy in target tissues. However, the immunological effects of these conjugates have not been investigated thoroughly. Here we modified used wood-based native (n)CNC, oxidized (ox-CNC) and phosphonate (3-AminoPropylphosphonic Acid (ApA))-conjugated CNC to test their physicochemical properties and immunomodulatory potential. Modification of CNC increased their elasticity module and hardness, which resulted in their reduced internalization by