Thrombus aspiration during primary percutaneous coronary intervention (pPCI) has been used to improve myocardial perfusion through a re du ction of the thrombotic burden eventually resul ting with better clinical outcomes.1,2 After the initial enthusiasm derived from the mortality reduction shown in early randomized and observational studies,3-7 disa ppointing results have been yielded in more recent larger scale trials testing the routine use of thrombus aspiration in pPCI.8-12 As a consequence, this technique has lost its initial appeal and currently is often neglected or even considered as a useless by the interventional cardiologists. The recent meta-analysis by Jolly et al.13 conducted in more than 18,000 patients once again re in forces the evidence that overall there is no benefit in the routine use of thrombus aspiration during pPCI. However, it has the merit to shed light on the residual potential of this technique, which has pro bably been dismissed too quickly. First, there were no significant differences in the occurrence of cardio va scular events up to 1-year post-pPCI between patients treated conventio nally versus those treated with routine adjunctive thrombus aspiration. Of interest, in the sub group of patients with large angiographic thrombus burden (i.e., TIMI thrombus grade ≥3), thrombus aspira tion was associated with a significant reduction in cardiovascular death [2.5 % vs. 3.1 %; hazard ratio 0.80, 95 % confidence interval (CI), 0.65–0.98, P=0.03]. This meta-analysis in fact assessed data from the three lar gest randomized trials on this topic, namely Thrombus Aspiration during Percutaneous coronary intervention in Acute myocardial infarction Study (TAPAS),4,5 Throm bus Aspiration in ST elevation Myocardial Infarction in Scandinavia (TASTE)8,9 and

The aim of this study was to detect the correlation between the change in the ambient temperature and adaptation of the pronephros – the main haematopoietic organ in fish, which so far has not been subject of research. Compared with other teleosts and their number of blood cells in peripheral blood, tench (Tinca tinca L. 1758) showed the corresponding trend of changes in number of pronephros haematopoietic cells after exposure to increased water temperature. The number of all haematopoietic cell lines was changed during the conditions of thermal stress (P<0.01; P<0.05). The number of erythroblasts was significantly reduced due to shift of haemoglobin curve of dissociation to the right. Leukopoietic cells were increased significantly as a response of pronephros to stress and all endocrine mediators of the stress (cortisol, leukine, etc.). The number of prothrombocytes was slightly decreased due to mobilisation into peripheral blood as in the case of cell precursor of monocytes. Eosinophilic and basophilic granuloblasts were not found in tench pronephros. Correlation (R) between body mass and total length was 0.526. Sex-specific variation of haematopoietic cells number in the same group was not observed (P>0.05), but it was significant between males or females among different groups (P<0.01; P<0.05 respectively).

This paper considers the effect of the discontinuity of electrolyte electrical conductivity on the distribution of potential and protective current density in cathodic protection systems with galvanic anodes. Its aim is to present a simultaneous application of both analytical and numerical models for the calculation of the distribution of protective potential and current density in the cases of homogeneous and double-layer electrolyte. For non-linear boundary conditions at the electrode surface (secondary distribution of protective current density), the indirect boundary element method is used, because of the complexity of calculation for which collocation at the point method was used. The calculation is further complicated due to the nonlinearity of boundary conditions at the electrode surfaces. In order to show the importance of this analysis, calculations for the observed system as well as of errors caused by neglecting the boundary discontinuity of the soil conductivity are provided. Based on these calculations and error analyses, the impact of the double-layer electrolyte on the correct calculation of the cathodic protection system with galvanic anodes is evaluated. This paper also provides the analysis when the double-layered nature of the electrolyte can be practically ignored, which is of great importance to designers of these systems.

This paper gives the methodology for driving power calculation of an apron feeder for ore transportation on the example of the apron feeder DO-F in the open pit of the Copper Mine Majdanpek. The analysis was done by calculation for given operating parameters. The apron feeder layout is also presented, as well as the technical characteristics of the driving unit elements.

We investigate global dynamics of the following systems of difference equations , , , where the parameters , , , , , and are positive numbers and the initial conditions and are arbitrary nonnegative numbers. This system is a version of the Leslie-Gower competition model for two species. We show that this system has rich dynamics which depends on the part of parametric space.