Educators, including teachers and professional associates, increasingly face challenges that extend beyond traditional pedagogical roles, particularly when working with children with developmental difficulties in inclusive educational settings. In addition to instructional responsibilities, they are expected to respond to diverse learning and behavioral needs, collaborate with multidisciplinary teams, communicate with families, and provide sustained emotional support to students. These demands require high levels of professional competence, flexibility, and emotional engagement, which can place considerable strain on educators’ psychological resources. This issue is particularly relevant in Bosnia and Herzegovina, where inclusive education has been formally promoted, but where structured support for educators is often fragmented. In such conditions, educators may rely heavily on personal commitment to compensate for systemic gaps, which may further increase vulnerability to stress and burnout. Thus, the aim of this review paper is to provide a systematic analysis of literature published between 2010 and 2025 focusing on psychological challenges faced by educators in Bosnia and Herzegovina. Both empirical and review studies addressing professional stress, emotional labor, emotion regulation, social support, and mental health interventions were examined. The findings indicate that effective emotion regulation, supportive work environments, and strong institutional and collegial support are key protective factors in preventing burnout and sustaining professional well-being.

Background: Laparoscopic appendectomy is the treatment of choice for acute appendicitis. The optimal technique of appendiceal stump closure is still under discussion because it is assumed to affect the occurrence of complications. The three-port combined technique with laparoscopically assisted extracorporeal base ligation (mesoappendix hemostasis performed intra-abdominally and the appendix ligated extra-abdominally) represents a novel technique with which to ligate the appendiceal stump following laparoscopic appendectomy. We compared this combined technique with the appendix stump treatment technique using an endoscopic loop, for complicated and uncomplicated appendicitis. Material and methods: In the period from January 1, 2020 to December 31, 2024, 628 patients under the age of 18 were operated on for appendicitis at the Clinic for Pediatric Surgery of the Clinical Center of the University of Sarajevo, 430(68.5%) with open appendectomy and 198(31,5%) with laparoscopic appendectomy We divided all the patients intotwo groups, group A with 102 patients who underwent surgery with a combined laparoscopic method, and group B where the base of the appendix was closed with an endoscopic loop (95 patients).Results: 198 patients underwent laparoscopic surgery, of which 123 (62%) were boys and 75 (38%) girls. Of these 198 patients who underwent laparoscopic surgery, 102 (52%) were treated using laparoscopically assisted extracorporeal ligation of the base of the appendix, 80 (40%) patients with one endoloop, 15 (8%) with 2 endoloops and only one patient with 1(0.5%) hem-o-lok and an endoloop. Of the 198 patients who were operated laparoscopically, 108 (54%) had complicated appendicitis, 59 (30%) uncomplicated appendicitis and 31 (16%) chronic appendicitis. The average duration of surgery for patients treated with the combined method was 58.61 minutes and with endoscopic loops 69.41 minutes. The average length of hospitalization for patients treated with the combined method was 3.96 days and with endoscopic loops 4.59 days.Conclusions: The three-port combined technique for laparoscopically assisted extracorporeal base ligation of the appendix is a safe, useful, and cost-effective alternative to endoscopic loops, with the advantages of less manipulation, fewer complications involving the appendix, and shorter operative times. This technique is particularly acceptable in resource-limited countries.

Aim: To identify the clinicopathological factors associated with five year mortality in patients with colorectal cancer (CRC) treated at Cantonal Hospital Zenica, Bosnia and Herzegovina. Methods: A retrospective cohort of 64 consecutively operated CRC patients (2019 2024) was analysed. The base-line variables included age, sex, tumor stage, histology, metastatic burden, local infiltration, and comorbidities. Five year cumulative mortality was the primary outcome. Risk ratios (RR) with 95 % confidence intervals (CI) were calculated by two by two contingency analysis.Results: The cohort comprised 26 women (40.6 %) and 38 men (59.4 %); their median age was 64 years (IQR 58.8–73.0). Eleven patients (17.2 %) died within five years. Mortality was strongly linked to tumor spread and cardiometabolic disease. Any distant metastasis conferred a fifteen fold increase in risk (9/15 vs 2/49; RR 14.7, 95 % CI 3.6–60.8, p < 0.001), and the involvement of two or more metastatic sites remained prognostic (RR 5.6, 95 % CI 1.9–16.9,p = 0.014). Infiltration of more than two adjacent organs quadrupled mortality (RR 4.4, 95 % CI 1.7–11.6, p = 0.032). Hypertension was present in 10 of the 11 deaths, yielding an RR of 12.1 (95 % CI 1.6–88.8, p = 0.002).Type 2 diabetes also increased risk (RR 3.5, 95 % CI 1.3–9.6, p = 0.040). Patients with three or more comorbid conditions had a nearly four times higher mortality (RR 3.9, 95 % CI 1.3–11.7, p = 0.027).Conclusion: The five year death rate in this Bosnian Herzegovinian CRC cohort was driven chiefly by distant metastasis, extensive local invasion, and cardiometabolic comorbidities—especially hypertension and type 2 diabetes. Early detection of metastatic spread and proactive management of vascular risk factors may improve survival in similar settings.

Jejunal diverticulosis is a rare condition that often presents asymptomatically, but can occasionally lead to severe complications, such as obstruction, perforation or bleeding. We report a case of an incarcerated ventral hernia resulting from massive jejunal diverticulosis, an unusual cause of bowel obstruction. An 80-year-old female patient presented with acute abdominal pain, nausea and vomiting. Physical examination revealed a tender, irreducible mass in the epigastric region. Exploratory surgery was performed and confirmed the presence of multiple jejunal diverticula, with one segment incarcerated in the epigastric hernia. The patient underwent successful surgical repair, including liberation of the affected jejunal segment and hernia repair. This case highlights the importance of considering jejunal diverticulosis in the differential diagnosis of bowel obstruction, and emphasizes the need for prompt surgical intervention in cases of complicated diverticulosis. Early diagnosis and appropriate management are critical inpreventing the severe morbidity and mortality associated with this condition.

Rapid industrialization has led to the creation of large amounts of wastewater containing various pollutants, among which heavy metals stand out. Heavy metals such as Cd (II) ions cause serious chronic diseases and even death if they are present in high concentrations. Therefore, this manuscript investigates the possibility of Cd (II) ion removal by precipitation method using Ca(OH)2. In order to optimize the precipitation process, the following were investigated: initial pH, initial concentration of Cd (II) ions, dose of added Ca(OH)2, stirring speed and contact time, as well as the influence of competing ions on the removal efficiency of Cd (II) ions. The optimization of the precipitation process was performed by varying one operational parameter at a time, while keeping all other parameters constant. Results of Cd(II) ion removal efficiency and optimal conditions are: pH 5 (99.961%), stirring speed of 0 rpm (99.985%), contact time metal-precipitant 5 minutes (99.965%), added dose of Ca(OH)2 60 mg (99.965%). Complete removal of Cd (II) ions was achieved at a Cd(II) ion concentration of 10 ppm, and high removal efficiency was achieved at concentrations of 50-300 ppm (98.231-99.994%). The removal efficiency of over 99% of Cd (II) ions was achieved during individual tests of ion competitiveness. Therefore, it can be concluded that under the tested conditions, Ca(OH)2 is an effective agent for removing Cd (II) with an efficiency above 99%.

Background and purpose This study investigates the influence of pedagogical qualification on the teaching of gymnastics in primary education, focusing on Slovak teachers’ instructional practices, resource utilization, and perceptions of teaching difficulty. Gymnastics is a foundational component of physical education (PE), promoting critical motor skills such as coordination, balance, and strength. Despite its benefits, gymnastics is often perceived as a difficult subject to teach, largely due to gaps in teacher training. Material and methods An online survey was completed by 1 189 actively employed primary school teachers across Slovakia during the 2023/2024 school year. Respondents were grouped by pedagogical background: 52.23% held preschool/elementary education qualifications, while 47.77% had alternative pedagogical training such as PE specialization. Results Results showed that “Gymnastics/Dance” was rated as the second most challenging thematic unit by both groups, with 28.18% of preschool/elementary-qualified teachers and 34.54% of other-qualified teachers selecting it, following “Health/Fitness” (38.49% and 37.18%, respectively). Although differences were not statistically significant (χ ²(3) = 7.56, p = 0.055), they highlight widespread difficulty with gymnastics instruction. Apparatus use was similarly high in both groups, with 66.34% of preschool/elementary-trained and 66.20% of other-qualified teachers reporting use of traditional gymnastics equipment. However, significant differences were observed in broader equipment use (χ²(3) = 12.84, p = 0.005), where 23.35% of preschool/elementary-trained teachers reported using both traditional and non-traditional tools compared to 17.96% of other-qualified teachers. Perceptions of facility adequacy also varied significantly (χ²(3) = 9.86, p = 0.018), with more critical ratings from preschool/ elementary-trained respondents. Conclusions These findings suggest that pedagogical training influences teaching diversity, expectations, and perceived support in gymnastics education. The study highlights the need for more robust, practice-focused training in gymnastics during teacher preparation, as well as improved access to equipment and facilities to support high-quality instruction.

Bosnia and Herzegovina (BiH) is governed by a complex constitutional framework. A complex police organization is imposed, among other things, by such a constitutional system. Furthermore, the inclusion of forensic departments or institutions in that framework suggests a complicated organization of forensic departments/institutes inside that structure. Forensic laboratory accreditation in accordance with the ISO 17025 standard is a requirement for forensic laboratories all over the world, so we would like to explain the concept of accreditation and the provisions of the ISO 17025 standard, as well as the reasons for the request for their implementation in the forensic services of Bosnia and Herzegovina. Using the content analysis approach, the authors examine the reasons imposed as an imperative for the implementation of the ISO 17025 standard in forensic practice in BiH. The foregoing is principally due to worldwide acknowledgment of the work's results, evaluation of the reliability of expert examinations conducted by judicial authorities at various levels throughout and fulfillment of the conditions for European Union membership. The concepts and findings in this study are based on theoretical postulates and empirical research conducted by the authors. The implementation of the ISO 17025 standard implies forensic laboratory accreditation, which in practice refers to determining the conformity of the applied methods, the requirement of adequate education and professional behavior of professional staff, and the use of appropriate instruments and equipment, all with the goal of fully expressing the principle of objectivity in criminal and civil proceedings.

Unambiguous identification of active sites in heterogeneous catalysis remains a major challenge, particularly for materials with ultrathin, chemically mixed surface layers. Here, we demonstrate a generalizable approach that combines time-of-flight secondary ion mass spectrometry (ToF-SIMS) with multivariate statistical analysis (principal component analysis [PCA] and multivariate curve resolution [MCR]) to resolve catalytically relevant motifs at the nanoscale. Using Ni electrodes as a model system, PCA distinguished hydroxide-enriched domains from oxide- and metal-rich regions, while MCR decomposed depth profiles and 3D images into hydroxide, oxide, and metallic layers with nanometer resolution. A unique secondary-ion fragment, NiO3H3 - (m/z 108.94), emerged as a marker of hydroxide-rich environments and correlated with hydrogen evolution reaction (HER) activity across a series of Ni electrodes. Complementary density functional theory (DFT) calculations revealed that Ni(OH)2 clusters adjacent to metallic Ni offer the most favorable water dissociation energetics, establishing the structural origin of the marker. While illustrated here for Ni-based HER, this workflow provides a broadly applicable framework to isolate and rank near-surface patterns that govern catalytic activity, thereby extending ToF-SIMS from a qualitative probe to a predictive tool for active site identification.

Abstract Due to the improved surge arresters’ technology and their low cost and simple installation, there is an increasing number of Line Surge Arresters (LSA) application to the overhead lines installed with the aim to improve the lightning protection of the lines and reduce the outage rate due to the lightning. In order to protect the overhead line from lightning it is advisable to know how does the lightning waveshape look like: what is the peak lightning current; maximum current steepness; charge transfer and specific energy. The experimental system for the measurement of lightning current circulating in line surge arresters and through the transmission line tower was installed on the 110 kV transmission line tower. It is equipped with the real-time monitoring and acquisition system for measuring the amplitude and shape of the currents through surge arresters and the overhead line tower. The newly designed system is based on the state-of-the-art in terms of measuring sensors, communication, and information technologies. The lightning current measuring system is equipped with the custom developed software, which will enable the system to download the data from the measuring device, to process the data and to transfer the data automatically to the cloud. The measuring system’s components are chosen according to the specific parameters of the lightning current. The knowledge gained from the measured data will help to define more precisely the procedures to be followed in engineering projects and to specify the phases and towers where line surge arresters have to be installed. On another level, the exploitation of several sources of information simultaneously will help to identify the way to take the maximum possible advantage of the data provided by the lightning detection system.

The construction industry consumes a substantial amount of resources. The associated environmental degradation and accelerating biodiversity loss highlight the urgent need for sustainable building materials that can match the performance of conventional alternatives. The objective of this experimental study was to investigate a fully reused, binder-free earth-based material that remains recyclable after its useful life. The material consists of smectite-rich excavation earth and processed demolition waste in a 2:1 ratio, which was compacted under high pressures and subsequently tested to evaluate its mechanical properties. Cylindrical specimens were fabricated via double-ended uniaxial compaction at pressures ranging from 12.5 to 100 MPa and consolidation times between 1 s and 30 min. They were then tested for their compressive strength and water durability. The findings indicate a strong positive correlation between compaction pressure, density, and compressive strength. A compressive strength of 19.2 MPa was reached by specimens that were compacted at 100 MPa for 30 min, achieving values comparable to standard C20/25 concrete. Despite an increase in strength, water durability decreased with increasing compaction pressure but improved with higher molding water content, possibly due to changes in the microstructure. The findings confirm that compressed earth can reach similar compressive strength to conventional materials with a significantly smaller ecological footprint.

The RSNA Lumbar Degenerative Imaging Spine Classification dataset is the largest publicly available adult MRI lumbar spine dataset for degenerative disease. The dataset includes multisequence, multiplanar MRIs from 2,697 patients through contributions from 8 institutions across 6 countries and 5 continents. ©RSNA, 2026.

Abstract Overhead transmission lines that consist of two or more circuits are frequently utilized as a solution in scenarios requiring the transmission of a higher amount of energy per unit of space, when spatial constraints exist, or to achieve cost savings in the construction and maintenance of transmission infrastructure. Despite their numerous advantages, these overhead transmission lines pose significant challenges concerning the intensity of magnetic fields in their vicinity. This paper presents an analysis of the influence zone of multi-circuit overhead transmission lines from the perspective of magnetic fields in the range of extremely low-frequencies. The zone of influence, in this context, is defined as the area surrounding the overhead transmission lines where the magnetic flux density exceeds specified reference values. To determine the magnetic flux density values, a methodology based on the application of artificial neural networks (ANNs) was employed. The paper outlines the implementation of this ANN based approach to estimate the magnetic flux density near multi-circuit overhead transmission lines. Two case studies are presented, examining double-circuit overhead transmission lines that have different configurations and rated voltages. For these cases, the zones of influence were determined with respect to extremely low-frequency magnetic field values. Additionally, a comparison was conducted between the obtained influence zones and the safety zones for overhead transmission lines defined by regulatory authorities.

A commercial biorepository of tumor samples with associated clinical data is crucial for discovering and validating biomarkers and advancing all stages of cancer research. Although oncogenic fusions are highly specific and attractive drug targets, the progress is limited by their diversity and low (1-4%) prevalence in solid tumors, outside prostate adenocarcinoma (>30% with a characteristic TMPRSS2::ERG fusion). Systematic, cost effective evaluation of banked tumor samples for the oncogenic fusions could accelerate such research efforts. We examined formalin-fixed paraffin-embedded tumor samples from a commercial biorepository (Reference Medicine, Phoenix, AZ) using a workflow which included expert pathology review, whole slide scanning, construction of multi-tumor tissue microarrays (TMA) immunohistochemistry (IHC) and genomic profiling with commercially available next generation sequencing (NGS) panels. More than 500 tumors were reviewed by board-certified pathologists; selected cases were then cored for TMAs. Immunohistochemistry for ALK and ROS1 proteins' expression were performed on TMAs. IHC for ALK and ROS1 identified two positive cases, one for ROS1 and one for ALK. Thirty eight tumors underwent NGS and both IHC-positive cases were confirmed to harbor gene fusions (EML4::ALK and EZR::ROS1, respectively). All other cases were fusion-negative, concordant with the IHC result. Properly characterized tissue samples are essential for image analysis, biomarker detection and genomic profiling. Rigorous pathologic review helps avoid archiving of poorly preserved samples. IHC screening of TMAs provides a cost-effective approach for identification of fusion events, particularly in non-small cell lung carcinomas, while preserving material for multiple downstream applications. Zoran Gatalica, Inga Rose, Semir Vranic. Detection of fusion oncogenes in routinely collected biorepository samples [abstract]. In: Proceedings of the AACR Special Conference in Cancer Research: Fusion-Positive Cancer: From Discovery to Therapy; 2026 Jan 13-15; Philadelphia PA. Philadelphia (PA): AACR; Cancer Res 2026;86(1_Suppl):Abstract nr A005.

The aim of this study was to evaluate the cost-effectiveness of extraction compared with restorative treatment of first permanent molars (FPMs) affected by Molar–Incisor Hypomineralisation (MIH) in 11-year-olds in Sweden. Seventy-five patients from the GuREx-MIH project were included. Of these, 43 were randomised to the Restorative treatment group (ReTG) and 32 to the Extraction treatment group (ExTG). Healthcare costs were calculated from dental records, while non-healthcare costs, were collected through surveys. Effectiveness was measured using the Child Perceptions Questionnaire (CPQ11-14) and the proportion of patients achieving a minimally important difference (MID). Incremental cost-effectiveness ratios (ICERs) were calculated as the difference in costs divided by the difference in effectiveness between groups. The ExTG incurred higher mean healthcare (€1,417 vs. €1,051; p = 0.029) and total costs (€2,950 vs. €2,161; p = 0.029) compared with the ReTG, almost entirely due to general anaesthesia (GA), while non-healthcare costs were (€1,531 vs. €1,111; p = 0.117). When patients treated under GA were excluded, the ExTG became less costly, with lower healthcare costs (€868 vs. €1,051; p = 0.039), fewer visits (9.2 vs. 11.4; p = 0.025), and shorter chair time (324 vs. 401 min; p = 0.040). ICERs showed that with GA, extraction was associated with higher incremental costs per MID responder (€2,593 healthcare; €6,110 total). Without GA, extraction was either dominant when only healthcare costs were considered or showed a cost of €4,201 per MID responder when considering total costs. Compared with restorative treatment, extraction was associated with higher healthcare and total costs, primarily due to general anaesthesia, but also linked with a greater proportion of patients achieving clinically meaningful improvements in oral health-related quality of life at the age of 11 years. The study was retrospectively registered on ClinicalTrials.gov 29th of January 2024, registration number: NCT06228989.