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Bin Zhou, James E Bennett, Aidan P Wickham, Rosie K. Singleton, Anu Mishra, R. Carrillo-Larco, Nayu Ikeda, Lakshya Jain et al.

Amira Jagodić Ejubović, M. Ejubović, Rijad Jahić, Amer Brkovic, Emina Letic, Milorad Vujnic, O. Lepara, Avdo Kurtović et al.

Background Acute pancreatitis (AP) is a condition with various etiological factors, marked by the sudden onset of inflammation in the pancreatic tissue. Predicting the severity and potential mortality of AP involves analyzing clinical data alongside laboratory tests and imaging. Among several grading methods with strong predictive capabilities for illness severity and mortality, the Bedside Index for Severity in Acute Pancreatitis (BISAP) score is notable. This study aims to explore the potential role of laboratory markers, specifically red cell distribution width (RDW), RDW/platelet (PLT) ratio, and mean platelet volume (MPV), in predicting disease severity, with patients being stratified according to the BISAP scoring system. Materials and methods This research included 161 patients hospitalized at Cantonal Hospital Zenica in Zenica, Bosnia and Herzegovina, with a diagnosis of AP. The BISAP score was determined based on laboratory and radiological analyses. This score was used to evaluate potential correlations between laboratory findings such as RDW, RDW/PLT ratio, and MPV. Results The age range was significantly higher in patients with BISAP scores ≥3 (68 years, 64-76) compared to those with BISAP scores <3 (59.5 years, 42.75-69) (p = 0.000). RDW values were also significantly higher in patients with BISAP scores ≥3 (15.6%, 14-16.9) compared to those with BISAP scores <3 (13.5%, 13-14.1) (p = 0.000). Hospital stay duration was significantly longer for patients with BISAP scores ≥3 (9 days, 6-11) compared to those with BISAP scores <3 (5 days, 5-7) (p = 0.000). Additionally, the RDW/PLT ratio was significantly lower in patients with BISAP scores <3 (0.063 ± 0.02) compared to those with BISAP scores ≥3 (0.09 ± 0.059) (p = 0.012). Conclusion Our results indicate a significant difference in RDW/PLT ratios between patient severity groups based on BISAP scores (scores <3 vs. ≥3). This suggests that the RDW/PLT ratio may serve as a useful predictor for assessing the severity of AP. However, further research is needed to explore the full potential of the RDW/PLT ratio in evaluating AP patients.

Almedina Moro, A. Softić, M. Travar, Šejla Goletić, J. Omeragić, Amira Koro-Spahić, N. Kapo, Visnja Mrdjen et al.

The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which led to the COVID-19 pandemic, has significantly impacted global public health. The proper diagnosis of SARS-CoV-2 infection is essential for the effective control and management of the disease. This study investigated the SARS-CoV-2 infection using RT-qPCR tests from laboratories in Bosnia and Herzegovina. We performed a retrospective study of demographic data and Ct values from 170,828 RT-qPCR tests from April 2020 to April 2023, representing 9.3% of total national testing. Samples were collected from 83,413 individuals across different age groups. Of all tests, 33.4% were positive for SARS-CoV-2, with Ct values and positivity rates varying across demographics and epidemic waves. The distribution was skewed towards older age groups, although lower positivity rates were observed in younger age groups. Ct values, indicative of viral load, ranged from 12.5 to 38. Lower Ct values correlated with higher positive case numbers, while higher Ct values signaled outbreak resolution. Additionally, Ct values decreased during epidemic waves but increased with the dominance of certain variants. Ct value-distribution has changed over time, particularly after the introduction of SARS-CoV-2 variants of interest/concern. Established Ct value trends might, therefore, be used as an early indicator and additional tool for informed decisions by public health authorities in SARS-CoV-2 and future prospective pandemics. Moreover, they should not be overlooked in future epidemiological events.

Marijana M. Kotlaja, Sanja Kutnjak Ivkovich, Jon Maskály, Sandra Kobajica, P. Neyroud

The current study applies the key components of GST to explore the relationship between stress and misconduct during the COVID-19 pandemic. We analyzed the answers provided by a sample of 480 police officers from Bosnia and Herzegovina and discovered that the relationship between strain and willingness to engage in police misconduct during the pandemic is complex; not all types of stressors were related to all forms of police misconduct included in our study. The two strongest organizational stressors were perceptions that the police agency was ineffective in dealing with the pandemic and that there was a lack of personal protective equipment for police officers. Fear for their own personal health, fear of COVID-19, and concerns that COVID-19 is much more dangerous than the flu were significant personal stressors related to their willingness to engage in police misconduct. Police's own willingness not to wear a mask and to visit friends and family with whom they do not live decreased the perception that the community is not adhering to the COVID-19 rules and regulations. Living with a partner was also negatively associated with the respondents’ willingness to engage in misconduct.

Elvis Hozdić, Redžo Hasanagić

This study investigates the impact of infill density on the mechanical properties of fused deposition modeling (FDM) 3D-printed polylactic acid (PLA) and PLA reinforced with carbon fiber (PLA+CF) specimens, which hold industrial significance due to their applications in industries where mechanical robustness and durability are critical. Exposure to cooling lubricants is particularly relevant for environments where these materials are frequently subjected to cooling fluids, such as manufacturing plants and machine shops. This research aims to explore insights into the mechanical robustness and durability of these materials under realistic operating conditions, including prolonged exposure to cooling lubricants. Tensile tests were performed on PLA and PLA+CF specimens printed with varying infill densities (40%, 60%, 80%, and 100%). The specimens underwent tensile testing before and after exposure to cooling lubricants for 7 and 30 days, respectively. Mechanical properties such as tensile strength, maximum force, strain, and Young’s modulus were measured to evaluate the effects of infill density and lubricant exposure. Higher infill densities significantly increased tensile strength and maximum force for both PLA and PLA+CF specimens. PLA specimens showed an increase in tensile strength from 22.49 MPa at 40% infill density to 45.00 MPa at 100% infill density, representing a 100.09% enhancement. PLA+CF specimens exhibited an increase from 23.09 MPa to 42.54 MPa, marking an 84.27% improvement. After 30 days of lubricant exposure, the tensile strength of PLA specimens decreased by 15.56%, while PLA+CF specimens experienced an 18.60% reduction. Strain values exhibited minor fluctuations, indicating stable elasticity, and Young’s modulus improved significantly with higher infill densities, suggesting enhanced material stiffness. Increasing the infill density of FDM 3D-printed PLA and PLA+CF specimens significantly enhance their mechanical properties, even under prolonged exposure to cooling lubricants. These findings have significant implications for industrial applications, indicating that optimizing infill density can enhance the durability and performance of 3D-printed components. This study offers a robust foundation for further research and practical applications, highlighting the critical role of infill density in enhancing structural integrity and load-bearing capacity.

D. Alexe, Denis Čaušević, Nedim Čović, B. Rani, D. Tohănean, Ensar Abazović, Edi Setiawan, C. I. Alexe

The association between movement screening and physical fitness testing in athletes is conflicting, and therefore, this study aimed to examine the relationship between Functional Movement Screen (FMS) performance and physical performance in elite female youth football players. Twenty-two players from the national U16 team of Bosnia and Herzegovina underwent FMS and physical performance tests, including speed, agility, and jump assessments. Jump and speed performance score correlated well with ASLR, while the overall FMS score was not associated with any of the performance variables. These findings suggest that while certain movement patterns may impact athletic performance, the relationship between movement screening and physical performance is delicate. Coaches and practitioners should consider individual variations and sport-specific demands when interpreting FMS results in order to optimize and maximize athlete performance and reduce injury risks.

Manuel M. Ferreira, F. Cardoso, S. Ambroziak, Mariella Särestöniemi, Kenan Turbic, Luís M. Correia

In this article, an analysis of system loss and depolarization in body area networks (BANs) for body-to-infrastructure (B2I) communications based on a measurement campaign in the 5.8 GHz band in an indoor environment is performed. Measurements were performed with an off-body antenna transmitting linearly polarized signals and dual-polarized receiving antennas carried by the user on the body. A normal distribution with a mean of 2.0 dB and a standard deviation of 4.3 dB is found to be the best fit for modeling cross-polarization (XP) discrimination. The average correlation between the signals received by the orthogonally polarized antennas is below 0.5, showing that polarization diversity can be used. A model for the average value of the standard deviation of the XP discrimination ratio as a function of the transmitted polarization, the mobility of users, and the link dynamics is presented, together with a detailed description of the methodology being used.

Johannes Deeg, Michael Swoboda, Daniel Egle, Verena Wieser, A. Soleiman, Valentin Ladenhauf, Malik Galijašević, Birgit Amort et al.

Background: A better understanding of the peritumoral stroma changes due to tumour invasion using non-invasive diagnostic methods may improve the differentiation between benign and malignant breast lesions. This study aimed to assess the correlation between breast lesion differentiation and intra- and peritumoral shear-wave elastography (SWE) gradients. Methods: A total of 135 patients with newly diagnosed breast lesions were included. Intratumoral, subsurface, and three consecutive peritumoral SWE value measurements (with three repetitions) were performed. Intratumoral, interface, and peritumoral gradients (Gradient 1 and Gradient 2) were calculated using averaged SWE values. Statistical analysis included descriptive statistics and an ordinary one-way ANOVA to compare overall and individual gradients among Breast Imaging-Reporting and Data System (BI-RADS) 2, 3, and 5 groups. Results: Malignant tumours showed higher average SWE velocity values at the tumour centre (BI-RADS 2/3: 4.1 ± 1.8 m/s vs. BI-RADS 5: 4.9 ± 2.0 m/s, p = 0.04) and the first peritumoral area (BI-RADS 2/3: 3.4 ± 1.8 m/s vs. BI-RADS 5: 4.3 ± 1.8 m/s, p = 0.003). No significant difference was found between intratumoral gradients (0.03 ± 0.32 m/s vs. 0.0 ± 0.28 m/s; p > 0.999) or gradients across the tumour–tissue interface (−0.17 ± 0.18 m/s vs. −0.13 ± 0.35 m/s; p = 0.202). However, the first peritumoral gradient (−0.16 ± 0.24 m/s vs. −0.35 ± 0.31 m/s; p < 0.0001) and the second peritumoral gradient (−0.11 ± 0.18 m/s vs. −0.22 ± 0.28 m/s; p = 0.037) were significantly steeper in malignant tumours. The AUC was best for PTG1 (0.7358) and PTG2 (0.7039). A threshold value for peritumoral SWI PT1 above 3.76 m/s and for PTG1 below −0.238 m/s·mm−1 indicated malignancy in 90.6% of cases. Conclusions: Evaluating the peritumoral SWE gradient may improve the diagnostic pre-test probability, as malignant tumours showed a significantly steeper curve of the elasticity values in the peritumoral stroma compared to the linear regression with a relatively flat curve of benign lesions.

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