The paper analyzes the traces of Roman temples in the area of today’s Bosnia and Herzegovina. In the general, introductory part, the notion of the temple in the Roman world is dealt with. The sacred places of the native population, which were mostly under the open sky, were analyzed. According to the findings found so far, most of the Roman sanctuaries are dedicated to Jupiter and Liber. A number of sites were also recorded, which were probably temples, and for which it is not possible to determine to which deity they were dedicated. The remains of the temples have not been preserved, except for a few substructures, so the analysis was done on the basis of epigraphic material and context.

Quantum Key Distribution (QKD) is an approach for establishing symmetrical binary keys between distant users in an information-theoretically secure way. In this paper we provide an overview of existing solutions that integrate QKD within the most popular architecture for establishing secure communications in modern IP (Internet Protocol) networks - IPsec (Internet Protocol security). The provided overview can be used to further design the integration of QKD within the IPsec architecture striving for a standardized solution.

A number of effective treatments are available for children and young people who have developed various forms of psychological difficulties as a consequence of traumatic experiences. The aim of this paper is to review the therapeutic approaches employed when working with children who have been exposed to various forms of abuse and neglect during their childhood. This paper provides relevant information to psychotherapists and counsellors on new trends in therapy, as well as techniques and possibilities in interventions in this field, not only with respect to traumatised children, but also family members and other caregivers involved in the child’s life. Furthermore, this paper reviews the therapeutic interventions used to treat emotionally, sexually, and physically abused children, neglected children, children who have witnessed domestic violence, and children who have been exposed to multiple forms of abuse.

Genetic intra-tumour heterogeneity fuels clonal evolution, but our understanding of clinically relevant clonal dynamics remain limited. We investigated spatial and temporal features of clonal diversification in clear cell renal cell carcinoma through a combination of modelling and real tumour analysis. We observe that the mode of tumour growth, surface or volume, impacts the extent of subclonal diversification, enabling interpretation of clonal diversity in patient tumours. Specific patterns of proliferation and necrosis explain clonal expansion and emergence of parallel evolution and microdiversity in tumours. In silico time-course studies reveal the appearance of budding structures before detectable subclonal diversification. Intriguingly, we observe radiological evidence of budding structures in early-stage clear cell renal cell carcinoma, indicating that future clonal evolution may be predictable from imaging. Our findings offer a window into the temporal and spatial features of clinically relevant clonal evolution. A combined modelling and tumour analysis approach is used to study the temporal and spatial patterns of subclone evolution in the TRACERx renal study. Studying the tumour shape and spatial features of clonal diversity in early-stage tumours may allow the prediction of tumour progression and patterns of subclone diversification over time.

U Bosni i Hercegovini nedostaje istraživanja na području valorizacije georaznolikosti, što je rezultiralo zanemarivanjem njezinih znanstvenih vrijednosti, ali i nedovoljnim razvojem geoturizma. Cilj je ovoga rada valorizirati odabrane geomorfolokalitete Parka prirode Blidinje s obzirom na njihovu geoturističku vrijednost. Primijenjeni metodološki koncept nastao je kao rezultat analize postojećih metodoloških koncepata valorizacije georaznolikosti, pri čemu su objedinjeni kriteriji za procjenu osnovne, dodane, zaštitne i turističke vrijednosti. Jedan od ciljeva rada jest i doprinos boljem razumijevanju i primjeni metodoloških koncepata turističke valorizacije, posebice u okviru zaštićenih prirodnih područja. Tijekom istraživanja izdvojena su 44 lokaliteta, a na osnovi rezultata preliminarne procjene kreirana je lista s ukupno 23 lokaliteta koji su valorizirani, od čega se njih osam izdvaja većom ocjenom od prosječne. Rezultati ovoga istraživanja upućuju na potencijal za razvoj ponude geoturizma PP Blidinje, čiji bi temelj trebali biti najbolje ocijenjeni geomorfolokaliteti.

The analysis of data from the first two decades of the 21st century shows that the area under forests in Bosnia and Herzegovina is gradually decreasing. In order to gain a detailed insight into this process, the paper will analyse the forest databases of the European satellite monitoring program Copernicus. This program, among other things, monitors the condition of forests in 39 European countries by using the High Resolution Layer (HRL). The HRL Forests database consists of 3 types of (status) products, and additional change products. The status products are available for the reference years 2012, 2015, and 2018. The status layers provide information on the Dominant Leaf Type and the Tree Cover Density at pixel level for the reference year 2018 in 10 m resolution. The Forest Type layer largely follows the Food and Agriculture Organization (FAO) forest definition. Also, the paper will use the data on forests from the CORINE Land Cover project for 2000, 2006, 2012 and 2018. The time-series includes a land change layer, highlighting changes in land cover and land use. The CLC Changes database will be analysed separately for three periods: 2000-2006, 2006-2012 and 2012-2018, due to more accurate data on forest losses. The results of the research show that forests in Bosnia and Herzegovina were reduced by 2.95%, in the period 2012-2018, where 2.55% of them were coniferous. Forests are primarily endangered by the process of conversion to transitional forest / shrub and fires.

Chikungunya virus (CHIKV) is considered a public health problem due to its rapid spread and high morbidity. In 2016–2017 an outbreak of CHIKV was occurred in Pakistan but the data regarding the genomic diversity of CHIKV was not reported. Hence, the current study aimed to determine the genetic diversity of CHIKVs in Pakistan. A cross sectional study was carried out using sera of infected CHIKV patients (n = 1549) during the outbreak in Pakistan (2016–2018). Nucleotide sequencing of non-structural genes of CHIKV from eight isolates were performed followed by phylogenetic analysis using Bayesian method. Phylogenetic analysis suggested that the Pakistani CHIKV strains belonged to Indian Ocean Lineage (IOL) of genotype ECSA and C1.3a clade. Furthermore, the Pakistani isolates showed several key mutations (nsP2-H130Y, nsP2-E145D, nsP4-S55N and nsP4- R85G) corresponding to mutations reported in 2016 Indian strains of CHIKV. The molecular analysis revealed high evolutionary potential of CHIKV strains as well as better understanding of enhanced virulence and pathogenesis of this outbreak. The study highlights the need to continue surveillance in order to understand viral diversity over time and to devise preventive measures to limit diseases transmission in the region.

The process of aging leads to changes in functional abilities, fitness levels, level of physical activity, and body mass index (BMI), all of which causes changes in the quality of life. The current study aims to determine the association between the level of physical activity (PA) and BMI, and quality of life (QoL) among elderly women. The total sample numbered 156 women, with an average age of 67.7 ± 5.6 years. To determine the level of physical activity, the self-reported International Physical Activity Questionnaire Long Form (IPAQ-LF), was used. To calculate the values of the BMI, the standard procedure recommended by the World Health Organization was used. Quality of life was evaluated using the short form of the WHOQOL-BREF questionnaire designed by the World Health Organization. All the data were processed using the statistical package for data analysis SPSS 20.0. Pearson’s correlation analysis shows statistically significant relations at the level of p < 0.01 between PA and Physical health in Housework = 0.36, Leisure time PA = 0.27, Walking = 0.24, Moderate PA 0.43, Total PA = 0.43, while the correlations between the variables at the significance level of p < 0.05 were determined in PA in transportation = 0.19 and High-intensity PA = 0.16. Multiple linear regression analysis of different levels of PA as independent variables on individual domains of QoL shows that there is an association of PA and Physical health (Sig = 0.000), more precisely, Total PA is statistically the most closely related to Physical health (Sig = 0.000), and then follows PA at work and Social relations (Sig = 0.036). Similar results were obtained when BMI is added to model A. In contrast to model A, model B shows a statistically significant association between PA and BMI with the environmental domain of QoL (Sig = 0.001). The results of the current study indicate that high- and moderate-intensity physical activity both have benefits for physical health, whereas moderate PA showed higher significance levels. Results also show that elderly women with higher BMI values achieve better results in the environmental domain of QoL.

The paper discusses the relationship between Marx's philosophy and the rule of law. The classical view of Marxism and the rule of law tells us that these are opposite notions. In this paper, the author presents different views in the context of the relationship between Marx's philosophy and the rule of law in relation to the classical Marxist view of the rule of law. Also, the author in this paper shows that Marx'sunderstanding of the rule of law does not necessarily contradict the modern concept of the rule of law, and also, Marx's understanding of the rule of law is related to the problem of building the rule of law in Bosnia and Herzegovina. The author conveys Marx's critique of 'law' as a critique of the process of building the rule of law in Bosnia and Herzegovina. In addition, the author shows that Marx's critique of 'law' is not necessarily an obstacle to the implementation of the modern concept of the rule of law.

Numerous studies are focused on discovering the factors involved in achieving school success or failure. Among the recognized factors are certainly the locus of control and procrastination. Research has shown that procrastination and locus of control are important indicators of school behavior, attitudes toward obligations, and indicators of school success (Sakač 2008; Košanski 2004). Therefore, this paper sought to determine the extent to which they play an important role in school success. The increasing interest in examining school success lies in being assessed as a significant factor in a child’s life. Its significance influences the development of self-confidence, satisfaction, success, and motivation. Within the research framework, school success was determined by school achievement at the end of the school year. The survey was conducted on 100 respondents of elementary school students, a sample is appropriate. During this research, the relationships between these variables were analyzed, the Anova procedure was used to analyze the data. The obtained results showed that procrastination and locus of control within this sample did not prove to be significant factors of school success.

Not all patients with cancer, in particular those with hematogic malignancies, develop functional immunity against SARS-CoV-2 variants of concern (VOC) following COVID-19 vaccines. Durability of vaccine-induced immunity after two doses and the impact of a third dose were evaluated in CAPTURE (NCT03226886), a longitudinal prospective cohort study of vaccine responses in patients with cancer. In evaluating 316 patients, at a median of 111 days following two doses of either BNT16b2 or ChadOX, we observed a time-dependant decline in neutralising antibody titres (NAbT) in a proportion of patients, where NAbTs became undetectable against Delta and Beta in 17% and 15% of patients, respectively. Vaccine-induced T cell responses declined in 44% of patients. Patients with breakthrough infections following two vaccines doses were characterised by absent/low NAbT to Delta prior to infection. Administration of the third vaccine dose boosted NAb responses against VOC in the majority of patients with cancer, especially those with solid cancer. In patients with hematologic malignancies who had undetectable NAbT against Delta after two vaccine doses, 54% did not develop NAb against both Beta and Delta following the third dose. Third vaccine dose boosted T cell responses were boosted in patients with both solid and hematologic malignancies. These results provide critical information on vaccine responses in patients with cancer, especially against VOCs and support widespread access to a third COVID-19 vaccination in this patient group.

Resistive random-access memories, also known as memristors, whose resistance can be modulated by the electrically driven formation and disruption of conductive filaments within an insulator, are promising candidates for neuromorphic applications due to their scalability, low-power operation and diverse functional behaviors. However, understanding the dynamics of individual filaments, and the surrounding material, is challenging, owing to the typically very large cross-sectional areas of test devices relative to the nanometer scale of individual filaments. In the present work, conductive atomic force microscopy is used to study the evolution of conductivity at the nanoscale in a fully CMOS-compatible silicon suboxide thin film. Distinct filamentary plasticity and background conductivity enhancement are reported, suggesting that device behavior might be best described by composite core (filament) and shell (background conductivity) dynamics. Furthermore, constant current measurements demonstrate an interplay between filament formation and rupture, resulting in current-controlled voltage spiking in nanoscale regions, with an estimated optimal energy consumption of 25 attojoules per spike. This is very promising for extremely low-power neuromorphic computation and suggests that the dynamic behavior observed in larger devices should persist and improve as dimensions are scaled down.

Rose family (Rosaceae) is one of  richest and most geographically widespread species of plant families. This family includes herbaceous and woody species, shrubs, and trees; the leaves are different, simple, or differently complex. The genus Fragaria (strawberry) includes perennial herbaceous plants. It is characteristic of this genus that the species are intensively vegetatively propagated using overhead stolons. The flowers are with a five-membered perianth and a developed outer cup. The flower has a larger number of anthers and carpels. A sample was taken at each site at least 30 individuals from the population in the flowering and fruiting phenophase. Morphological variability was assessed based on 5 populations and 150 individuals. This paper aims to determine the most variable and most consistent morphological characters that can serve in full and critical taxonomic analysis and revision of this variable taxon as well as related taxa from the family Rosaceae. Determine the forms and levels of individual, population, and interpopulation variability of the species Fragaria vesca L. depending on the environmental factors under which develop. Conducted comparative morphological analyzes have shown that the species Fragaria vesca L. shows a high degree of variability for all analyzed characters. Vegetative plant characters have a far greater share in overall variability compared to generative ones character. Pold does not belong to the group of those plant parts that vary the most.

: Research shows that there is a significant resources waste in construction, and accordingly lagging in productivity behind the productivity of the global economy and industry in particular. There is also a small number of papers and studies on this waste. On the other hand, a higher productivity level requires small waste of material, energy and other inputs. Therefore, construction companies are deciding to introduce lean as one of the leading methods of waste reduction. This paper deals with the introduction of lean in construction companies in BiH, currently at very low level. Bearing in mind that most construction companies in BiH are small, it concludes that introducing lean and thus reducing the resources waste and increasing productivity and competitiveness requires more information and particularly skills improvements.