Aim There are more and more herbal preparations that are used for the purpose of treatment and improvement of the clinical manifestation of vaginitis not only by patients themselves, but also by healthcare professionals. Plant species, St. John's wort, chamomile, calendula, yarrow, shepherd's purse and tea tree oil are all well known for their anti-inflammatory, antimicrobial and wound healing activity. This paper presents the results of a clinical study in which three herbal formulations/vagitories, based on extracts of St. John's wort, chamomile, calendula, yarrow, shepherd's purse and tea tree oil, were investigated for their effectiveness on vaginitis. Methods This was a randomized controlled clinical study that included 210 women with diagnosed vaginitis. Patients were divided into two basic groups, women in reproductive period and postmenopausal period. Three subgroups including 30 patients each received one of the three vagitorie formulations for 5 days, after which the effects on subjective and objective symptoms were monitored. Results Three types of vagitories based on plant extracts had a positive effect in the treatment of vaginitis. Vagitories based on tea tree oil showed better efficiency compared to vagitories with St. John's wort and vagitories based on extracts of five plants. Women in postmenopausal group reported better tolerability of St. John's wort-based and five herbs-based vagitories compared to tea tree oil based vagitories. Conclusion Investigated vagitories showed a positive effect on both objective and subjective symptoms of vagitnis. No serious side effects were reported.

Aim To evaluate modalities of extensor tendons repair of hand and forearm in specific anatomical zones with regard to etiological factors and presence of associated injuries of adjacent anatomical structures. Methods This cross-sectional study included 279 patients referred for extensor tendon repair of hand and forearm in specific anatomical zones. Available treatment modalities were evaluated concerning etiological factors, anatomical zones, and associated injuries. Statistical significance was analysed in the occurrence of early and late postoperative complications according to anatomical zones. Results Direct repair of extensor tendon lesions was found to be the most common modality of reconstruction, 230 (93.5%), of which blade injuries were predominant, 120 (48.7%). Direct tendon repair was mostly indicated in Zone VI and Zone III, in 55 (23.9%) and 42 (18.3%) patients, respectively. Statistically, a significant correlation was confirmed between treatment modalities, injuries in specific anatomical zones, and type of etiological factor (p<0.0001). Statistical correlation was confirmed between zones of injuries and the occurrence of early and late complications (p=0.002). Conclusion Successful postoperative recovery was correlated with the recognition of functional failure in specific zones, assessment of potential associated injuries, and selection of the most optimal modality of reconstruction.

Aim To investigate the effect of intermittent traction therapy (ITT) on pain in patients with chronic low back pain (CLBP). Methods A total of 81 patients with CLBP were included: experimental group received ITT (n=40) and control group received conservative physical treatment (n=41) 10 times for two weeks. A visual analogue scale (VAS) was used for measuring low back pain. Results In the experimental group, 26 (out of 40; 65.0%) patients were females, in the control group 20 (out of 41; 48.8%) were females (p=0.141). In a within-group comparison, median of VAS value was significantly decreased in both groups after ITT. A comparison of pre-intervention and post-intervention VAS value showed no statistically significant difference. Females from the experimental group had a significantly greater decrease of VAS compared with females from the control group. Patients in the ITT group with L5/S1 level of hernia had lower estimated marginal mean of VAS scale compared to the control group, as well the patients with left side of leg pain. Conclusion: Intermittent traction therapy is an effective treatment for pain reduction in patients with chronic low back pain.

Background: Psoriasis is a chronic incurable disease, and patients develop associated diseases such as obesity, diabetes, high blood pressure, dyslipidemia. Objective: The aim of the study is to determine the frequency of comorbidities (obesity, diabetes, dyslipidemia, high blood pressure) in men with psoriasis, and the relationship between the duration of psoriasis and the occurrence of comorbidities. Methods: A prospective study was conducted and included 88 male subjects, mean age 52,70 (SD=± 14,05) years, mean psoriasis duration 15,13 (SD=±12,43) years. Results: The incidence of obesity was 30,68%, high blood pressure 29,55%, dyslipidemia 22,73%, diabetes 13,64%. There was a weak correlation between the duration of psoriasis and the occurrence of obesity (r=0,11), dyslipidemia (r=0,18), diabetes (r=0,01), and high blood pressure (r=-0,02). Conclusion: Comorbidities occur in men with psoriasis, and their occurrence is not related to the duration of the disease.

Phishing is a network attack in which attacker generates a replica of current legitimate site to contrivance the users into submitting their personal and sensitive information. A good anti-phishing solution should have rapid access time and rapid detection rate, but most of the existing solutions fail to satisfy it. A new method is proposed to prevent phishing attack which evaluates the URL Characteristics and cross check with the white-list. The proposed method has higher access time and higher detection rate than other methods. Whenever the user opens a website for the first time which is not available in the white-list, the algorithm proposed here examines the webpage using URL characteristics. The experimental results depict the accuracy of proposed method having accuracy of 93.8% with less negative rate.

The paper describes the PyChart module (aimed at analysis and visual view of 2D/3D Charts), which was created with the help of free and Open Source resources, using Python as a programming language and wx.Python as a graphical user interface toolkit. The chart data is imported from a Excel/CSV file with a template structure and is drawn in the PyChart module as XY or XYZ curves similar with Excel scatter with smooth lines and markers style. The main functions of the charts are activated using the toolbar. The module is provided with zooming instruments (fit, pan, zoom in, zoom out), cubic spline curves interpolation, chart intersection with constant X, Y or Z values, visual follow of the 2D chart points to view coordinates, export of data in Windows Clipboard, Excel or Microsoft Word format and saving the chart as a image file.

Shape analysis is an important and powerful tool in a wide variety of medical applications. Many shape analysis techniques require shape representations which are in correspondence. Unfortunately, popular techniques for generating shape representations do not handle objects with complex geometry or topology well, and those that do are not typically readily available for non-expert users. We describe a method for generating correspondences across a population of objects using a given template. We also describe its implementation and distribution via SlicerSALT, an open-source platform for making powerful shape analysis techniques more widely available and usable. Finally, we show results of this implementation on mouse femur data.

Objectives: To avoid hospital spread of Coronavirus-2019 (COVID-19) and to analyze out of hospital outcomes after amputation. Methods: Prospective analysis of data obtained from 60 diabetic patients in 2020 was performed at Cantonal Hospital Zenica, Zenica, Bosnia and Herzegovina. Personal protection equipment included double surgical mask, glasses, disposable surgical coats, and surgical masks for patients. Swabs were used to take samples from wounds. We randomly divided patients in 2 groups of 30 patients each. In pre-operative treatment, we used local anesthesia lidocaine hydrochloride 2% (Belupo, Koprivnica, Croatia) in group A and systemic analgesia intravenous tramadol chloride 100 mg intravenous (Krka, Novo Mesto, Slovenia) in group B. Wounds were surgically treated each day and heal spontaneously. Periodical control exams were performed. Results: Wound healing did not present any statistically significant differences between groups (group A: 69±21.97 and B: 61±22.13 days, t=−1.22; p=0.11). No statistically significant differences (p<0.05) between groups A and B in wound healing regarding to gender or cigarette use was noted. Conclusion: No significant differences in amputation treatment between the 2 comparative groups were noted. No confirmed COVID-19 infections in medical staff who performed surgical interventions or in treated patients were detected.

The study of atomic spectra is one of the key subjects in teaching physics. It represents a combination of topics such as wave physics, atomic physics, particle physics, etc. Because of its complexity, it takes a well-prepared student and a very creative and resourceful teacher for this subject to be adequately understood and comprehended. This article presents theoretical background with key points in physics that help teachers to better organize their preparation for students and different experimental sets for this specific experiment, such as Nikola Tesla’s transformer or some other high-voltage transformers. Another point of view for this experiment is a variety of subexperiment possibilities to choose from in the execution of this practical exercise. This article also brings some difficulties that both teachers and students experience while preparing or doing this experiment, such as lack of more profound quantum physics knowledge since the conventional approach in teaching this specific topic in high schools and universities focuses on an introductory course in the history of this topic-oriented towards early years of the 20th century.

Dark matter as one of the cosmos’ ingredients or constituents has been searched for in various experiments. This review presents some of the searches for dark matter while focusing on the LHC mainly. In order to present various searches, it describes theoretical models followed by experimental verification. Since there are three types of searches, among which most significant are direct and indirect ones, we will give an overview and short comparison between the two, with an emphasis on the advantages and disadvantages of collider and non-collider searches. This review brings an argumentative approach for the collider’s point of view since searches for dark matter in colliders are veritably ambitious regarding direct and indirect Dark Matter detection methods. LHC starts its Run 3 in 2021, and here we present results from the ATLAS experiment from Run 2 and bring some theoretical expectations from LHC in Run 3.

There are several theoretical models proposing dark matter candidates as well as different experimental searches for dark matter, collider, and non-collider ones. One of the most intriguing dark matter candidates is missing information in the cosmos. This is based on the mass-energy-information equivalence principle presented by M Vopson [1]. This review presents the historical development of this principle from its roots in the 1960s when Landauer principle was firstly presented to the latest data on the estimated value of the mass of one bit of information as well as data on missing energy as potential dark matter. Another theoretical discussion presented here is the reformulation of the second law of thermodynamics as a possible step to great unification. In addition to this theoretical postulation with a mathematical presentation focusing on statistics, we present some of the proposed experiments in this field. Two major proposals are in the direction of using an ultra-accurate balance with measurement uncertainty low enough to be comparable with proposed theoretical limits, and originally developed sensitive interferometer similar to the one in LIGO experiment.