As an oxygen carrier and a strong oxidising agent, ammonium nitrate can create an explosive mixture when mixed with organic material. A typical example is the mixture of ammonium nitrate and fuel oil (ANFO), which is the most used explosive for civilian applications. In this work, we studied the detonability and detonation properties of mixtures of ammonium nitrate with recycled rubber and hay. The main goal of this study was to determine the optimal volume ratio of ammonium nitrate and organic materials in terms of achieving the best performance (working capacity). Using small experiments, it was determined that the maximum burst velocity for the ammonium nitrate/hay mixture is achieved at 8% hay by volume, while the maximum burst velocity for the ammonium nitrate/rubber mixture is achieved at 15% rubber by volume. A thermochemical calculation has shown that the maximum detonation heat is achieved at the zero oxygen balance at the volume ratios of 89.2/10.8 for AN/Rubber and 72.85/27.15 for AN/Hay.

This study explores the anatomical relationship between iliac blood vessels and the lower lumbar spine during supine and prone patient positions. The average height of participants was 174.02 cm ± 9.01, while the average weight was 80.38 kg ± 13.48. Body mass index (BMI) analyses showed differences (p = 0.002), with 34.7% classified as normal weight, 53.1% as overweight, and 12.2% as moderately obese. The study examined the distances between iliac arteries and veins in relation to intervertebral anterior and posterior disc contours. Patient positioning significantly affected these measurements at both L4/L5 and L5/S1 levels. The findings highlight the critical influence of body position on anatomical relationships in the context of lower lumbar spine surgery. The study underscores the importance of preoperative awareness of vascular anatomy to prevent iatrogenic lesions during spine surgery, contributing valuable insights for optimizing surgical approaches and minimizing complications in spine surgery, particularly microdiscectomy.

: This paper describes the possibility of applying heuristic methods for parameter optimization in the TCP protocol. The proposed concept provides for a TCP protocol adjusting its parameters for greater efficiency through testing the network state and adapting accordingly. This can be achieved through careful analysis of the network state both before and during data transfer connections. The proposed solution introduces an innovative approach, incorporating the possibility of self-learning and self-adjusting capabilities. This sophisticated algorithm should define the next parameter values in terms of finding optimal parameter settings. Each TCP connection plays a crucial role as iteration in the process of finding the optimal solution. The concept focuses on calculating TCP parameter values at the network ends in order to optimize network traffic and to maximize the use of network resources. The approach has been tested on a dedicated test platform, validating its potential for verifying the network protocols functionality and for optimizing their parameters. The proposed solution, here referred to as the modified TCP, showed better performance compared to other versions of the TCP protocol. Notably, even under heavy traffic loads on links, the results for the modified TCP consistently outperform the standard TCP, delivering results that are several times better.

We aimed to assess the extent of integration of non‐communicable disease (NCD) assessment and management in HIV clinics across Europe.

ABSTRACT The objectives of this study were to investigate: 1) whether there were morning-to-evening differences in short-term maximal performance and 2) the impact of prolonged and specific warm-up on short-term maximal performance diurnal variations in young basketball players. Fifteen basketball players of both sexes (Male = 8; Female = 7; age: 14.4 ± 0.46 yr; weight: 64.7 ± 7.1 kg; height: 175.2 ± 6.6 cm; BMI: 21.1 ± 1.9 kg/m2) completed the following short-term maximal performance tests: CMJ with and without arm swing, Lane Agility Drill, Zig-Zag agility test with and without the ball, Sprint 20 m with and without the ball with the passage at 5 and 10 m. All tests were performed after the 15-min standard warm-up procedure (with static stretching) and/or 25-min specific warm-up (with prolonged running and dynamic stretching) in the morning and evening. Vertical jumping tests and all change-of-direction speed tests (with and without a ball) with superior responses were achieved in the evening after standard warm-up among all participants (p < 0.05). In contrast, superior short-term maximal performance was observed in the morning after prolonged and specific warm-up protocol (p < 0.05). It was concluded that specific and prolonged warm-up protocols are suitable strategy to prevent diurnal variation in short-term maximal performance in young basketball players.

Velika Britanija je primarno zbog njenih strateških interesa na Istoku i održanja ravnoteže u Evropi u 19. stoljeću važila za zaštitnika Osmanskog carstva, a zalaganje za očuvanje nezavisnosti i integriteta osmanske države bili su proklamirani temelji britanske politike u Istočnom pitanju. U tom pravcu se Britanija obavezala tri puta: Pariškim i Tripartitnim sporazumomiz 1856, te Londonskim iz 1871. godine. Podršci Porti je dodatno doprinosilo mišljenje u Londonu da moguće alternative osmanskoj vlasti na jugoistoku Evrope i na Bliskom istoku (ruska kontrola tih prostora ih vlast novonastalih balkanskih hrišćanskih kneževina) neće Velikoj Britaniji i Britancima omogućavati slobodan prolaz ka Indiji i slobodnu trgovinu i zaštitu već uloženog kapitala, kao stoje to slučaj s Osmanskim carstvom. Odbrana britanskih interesa na globalnom nivou podrazumijevala je snažnu flotu i spremnost da se ista upotrijebi kada druge metode ne uspiju. To je bila krajnja mjera, a prijetoga Velika Britanija je svoje interese i interese svojih podanika branila državnim autoritetom i razgranatom diplomatskom i konzularnom mrežom. 0 tome govori i činjenica daje u drugoj polovini XIX stoljeća samo u evropskom dijelu Osmanskog Carstva imala 10 konzulata i 16 vicekonzulata. 

Vlasi Nenkovići, u literaturi tretirani i kao Nenkovci, nemaju u cjelini poznatu srednjovjekovnu razvojnu liniju. Taj zadatak predstavlja delegirano polazište kojim se pozabavio i ovaj rad. Zna se da je kretanje po usitnjenim podacima iz vlaške problematike za srednjovjekovno razdoblje izuzetno otežano. Međutim, zna se i da veći broj prikupljenih podataka omogućava  i njihovo lakše sagledavanje i kontekstualiziranje. Takvim se pokazala naša prikupljena baza podataka u kojoj je linija predstavnika jedne katunarske porodice postala prepoznatljivoj om u svoja tri koljena, ali još važnije, u osnovnoj liniji nastanka vlaha Nenkovića koji su izrasli iz širih okvira vlaha Burmaza.

Minerals are essential substances with an important function in livestock, and their disbalance negatively affects the health and production, especially of ruminants. The addition of fat to the rations of dairy cows impacts the overall and mineral metabolism, and thus on health and production. The aim of the research was to examine the correlative relationships between balanced production meals and the mineral status of lactating cows with different ration compositions with or without the presence of vegetable oil. The research was conducted on 30 dairy cows of the Holstein breed at the Butmir farm, Sarajevo, Bosnia and Herzegovina. Three groups of 10 animals were formed based on productivity (A, 13-15 kg of milk/day, B, 19-21 kg of milk/day and C, 25-27 kg of milk/day). Samples of feed, blood plasma and milk of animals were collected on three occasions a 3-week intervals. According to the feed analysis results, the rations were standardized for each group, given for three weeks without oil,and then for three weeks with the addition of sunflower oil in the amount of 2.5% of the ration dry matter. After determining the content of basic nutrients, dry matter and ash in the rations, the concentrations of Ca, Mg, Na and K were determined by atomic absorption spectrophotometry,while the colorimetric method was used to analyse P according to Woy and Eggertz-Finkener. Analysis of blood mineral parameters was performed spectrophotometrically. The content of fat, proteins, lactose, and non-fat dry matter in milk samples was determined by infrared spectrometry using an automatic analyser. Based on the results, we observed a similarity in changes of values and the statistical significance of the differences in plasma Ca, P and Mg between the study groups and at sampling intervals. Milk production was positively correlated with the concentration of Mg and Ca with addition of the sunflower oil to the meal, while no correlation coefficient was established for P in any of the samplings. Balanced meals with and without the addition of oil did not significantly affect the content of Ca, P or Mg in the blood plasma of the tested animals, nor were significant differences found between the groups. However, by determining the correlations between milk parameters and blood biochemical parameters, a significant positive correlation was established between the amount of milk and Ca and Mg levels with a diet supplemented by oil. Given that the addition of sunflower oil in the amount of 2.5% of dry matter of the balanced rations for cows had no negative effects on the mineral profile and the parameters of the tested animals, we conclude that the introduction of this oil could be useful both from the economic point and improving nutritional composition of milk as an animal food present in the daily human diet.

This paper aimed to characterize the phytochemical profile and bioactivities of 22 plant species used in the traditional medicine of Bosnia and Herzegovina. The utilization of plants in traditional medicine in Bosnia and Herzegovina holds significant importance, not only as a reflection of cultural heritage but also as a sustainable and time-tested approach to healthcare, fostering a harmonious connection between nature and well-being. The comprehensive analyses encompassed the determination of total phenolic and flavonoid content, alongside assessing antioxidant activity using DPPH and FRAP assays. Additionally, antimicrobial activity was tested against S. aureus. ssp. aureus, MRSA, P. aeruginosa, S. abony and C. albicans. Many of the analyzed plant extracts showed a high phenolic content (C. avellana, V. myrtillus) and antioxidant activity (C. avellana, V. myrtillus, B. pendula, S. officinale, E. angustifolium, J. globifera ssp. hirta). The majority of extracts showed good antimicrobial activity for S. aureus ssp. aureus and MRSA. The E. angustifolium extract was effective against all tested bacterial strains, with MIC values ranging from 1.25-10 mg/mL. The research identified significant levels of secondary metabolites and identified plant species with potent antioxidant and antimicrobial activity. The study also revealed significant correlations among various phytochemical parameters and bioactivities.

Aim: The primary aim of the study was to determine the incidence of testicular neoplasms in the Zenica-Doboj Canton (ZDC) region for the period from 2019 to 2021. Also, the study aimed to examine the age structure of the affected population, the frequency of testicular neoplasms in all the ZDC cities and municipalities, and the pathohistological characteristics of neoplasms. Material and methods: The study was conducted at the Oncology and Radiotherapy Department of the Zenica Cantonal Hospital. The study period refers to the time interval from January 2019 to December 2021. The study included 37 patients with a verified diagnosis of testicular neoplasm. Results: Arithmetic mean of patients’ age was 33.49 years, while the standard deviation was 12.59. Most respondents, accounting for 40.5%, were aged 26-35 years. The incidence of testicular neoplasms in the ZDC region was 4.2/100,000 per - sons in 2019, 3.08/100,000 persons in 2020, and 3.10/100,000 persons in 2021. Most diagnosed neoplasms (48.6%) were the myxoid type germ cell originating tumors. Conclusion: The incidence of testicular neoplasms in the ZDC was 4.2/100,000 persons in 2019, 3.08/100,000 persons in 2020, and 3.10/100,000 persons in 2021.

Primary osteoarthritis (POA) is a complex hereditary disease that involves the interplay between genetics and epigenetics. MicroRNA molecules play important roles in epigenetic mechanisms. MicroRNA‐146a (miR‐146a) is a negative regulator of the immune response in osteoarthritis (OA). So, variations in the miR‐146a gene could affect OA risk. The aim of this study was to investigate the relationships between single nucleotide polymorphisms (SNPs) in the miR‐146a, interleukin‐6 (IL‐6), Toll‐like receptor 10 (TLR10), and tumor necrosis factor‐alpha (TNFA) genes and the risk for development of advanced‐stage primary hip osteoarthritis (PHOA) and primary knee osteoarthritis (PKOA) in the Croatian population. A total of 609 POA patients and 656 healthy donors were genotyped for SNPs in the miR‐146a (rs2910164, G>C). Since we used same patients and controls as two studies before us, we already had information about IL‐6 (rs1800795, C>G), TLR10 (rs11096957, C>T), and TNFA (rs1800629, C>T) genotypes of our subjects. None of the differences were statistically significant comparing either allelic or genotypic frequencies of miR‐146a SNP rs2910164 (G>C) between the PHOA and PKOA patients and controls. However, we found a significant association with risk to PHOA for the combination of genotypes (stratified miR‐146a genotype with the IL‐6, and stratified miR‐146a genotype with the TNFA). In a multifactorial disease such as POA, we have shown the indirect relevance of a second modifying factor (miR‐146a), which apparently contributes to the overall risk of PHOA. There was no risk association with the PKOA, indicating that these two localities (hip and knee) might have different risk‐modifying factors.

By virtue of several European visionaries, led by Robert Schuman and Jean Monnet, whose noble goal was to end centuries of wars and bloodshed on the European continent, today we have the European Union, the most successful integration project of the 20th century. The European Union has come a long way to achieve the ultimate goal of political stability, based on equality in diversity, rule of law, democracy and respect for human rights, as well as the economic growth and development of all its members. From the original six countries that founded the European Coal and Steel Community in 1951, the European Union, through seven rounds of enlargement, has grown into a community of 27 prosperous countries, which both individually and together within the Union, have become a significant player on the global political and economic scene. The aim of this paper is to research and analyze the complexity of the European Union enlargement policy, its preferences and downsides, with special emphasis on Bosnia and Herzegovina and its integration processes, following its recent candidate status. The main research objective is to identify the factors that may enable or constrain effective EU enlargement policy and its implementation in BiH. The paper argues that the final goal - the EU acquis transposition and enforcement by enlargement countries - may present the biggest hurdle on the EU trajectory. The research methods include qualitative methods - analysis of the relevant literature, publications, official EU data, as well as the EU and BiH policy documents and strategies.

This study explores the correlation between immunological and clinical characteristics in coronavirus disease 2019 (COVID-19) patients with detectable severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA in feces, analyzing data from 251 patients admitted to Mostar University Clinical Hospital (UCH) from December 2021 to January 2022. Methods involved reverse transcription quantitative polymerase chain reaction (RT-qPCR) from nasopharyngeal (NP) swabs and feces, alongside serological tests for anti-SARS-CoV-2 spike IgGs. Demographic and clinical data were collected through questionnaires and medical records. The data analyses were performed using SPSS statistical software. Death occurred in 53 patients (21.1%, P < 0.001), mostly in the elderly (47/53, 88.7%, P ═ 0.001) and immunocompromised (19/53, 35.8%, P ═ 0.05), particularly those developing acute respiratory insufficiency (ARI) (46/53, 86.8%, P ═ 0.004), and severe/critical disease (46/53, 86.8%, P ═ 0.002). Among the patients with positive anti-SARS-CoV-2 IgG antibodies (86/251, 34.3%, P < 0.001), 41 (47.7%) were vaccinated and 45 (52.3%) unvaccinated (P ═ 0.666), showing no significant differences in clinical outcomes or mortality. Unvaccinated patients with a negative antibody titer had a higher incidence of ARI (96/123, 78%, P ═ 0.029) and intensive care unit (ICU) admission (22/123, 17.9%, P ═ 0.026), than those with a positive antibody titer. Forty-seven (62.7%) patients, out of the 75 hospitalized who provided a feces sample, were positive for SARS-CoV-2 RNA (P ═ 0.028), without statistical differences between fecal SARS-CoV-2 positive and negative groups regarding vaccination status (15/47, 31.9%, P ═ 0.493), antibody status (18/47, 38.3%, P ═ 0.628), or death outcome (5/47, 10.6%, P ═ 0.706). In conclusion, unvaccinated hospitalized patients with a severe COVID-19 presentation and a negative anti-spike SARS-CoV-2 IgG titer had adverse outcomes more frequently. This suggests cautious consideration for the diagnostic use of fecal samples compared to NP swabs.