Abstract Background: Low-grade chronic inflammation is an important feature of chronic kidney disease (CKD). Aim: To determine the values of C-reactive protein (CRP), neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) in patients with different stages of CKD and to examine how they change depending on the progression of renal damage. Materials and methods: A cross-sectional descriptive comparative study included 157 subjects at different stages of CKD which was assessed based on glomerular filtration rate (GFR) calculated according to the MDRD equation. CRP was analyzed by an immunoturbidimetric method. NLR and PLR were calculated by a mathematical calculation after a blood count was performed. Results: The present study showed an increase in serum creatinine, CRP, and NLR values with progression of renal failure. There was a statistically significant difference in the creatinine and CRP concentrations between groups with different stages of CKD (p <0.001 for all comparisons). A significant positive correlation was found between NLR and CRP, while negative, significant correlations were observed between NLR and eGFR as well as between PLR and eGFR. There was a slight increase in PLR value with the progression of renal impairment, but the correlation between PLR and CRP was not significant. Conclusion: These results suggest that NLR, together with CRP, may serve as an indicator of systemic low-grade inflammation progression in patients with CKD. Larger prospective studies are required to observe the possibility of using NLR as a surrogate marker for CRP in patients with CKD.
Brown coal mining conducted at greater depths, characterised with severe mining-geological conditions often results in deviation from the applied mining methods. Experiences gained in mechanised longwall mining of roof plate in deeper parts of Raspotočje mine, using method of roof caving without safety pillars left behind the working panels indicates to shortcomings of the applying mining method. Frequent occurences of spontaneous mine fires, of hazardous gasses well above the limit values, and constant exposure to rock bursts of various in- tensity resulted in application of three longwall face ventilation regimes: conventional „U“ ventilation system, ventilation with gas channel and middle hallway, and separate ventilation of the upper part of the longwall face. This paper presents experience based information gained in a five years period of mining, analysed using one- factor and two factor regression analyses applied to a number of technical-technological parameters (ventilation, mining system, etc) influencing occurences of spontaneous mine fires and increased gas release in various ventilation regimes at longwall face aimed to give basic guidelines for minimisation and elimination of certain hazards. Keywords: ventilation regime, spontaneous fires, gas release, mechanised longwall.
Abstract Considering the burning problem of corruption and non-transparency of public enterprises in the Federation of Bosnia and Herzegovina (FBiH), the paper aims to investigate whether the Beneish M-score model can be used to predict inaccurate financial statements. Where, the cause of inaccurate financial statements are intentional or unintentional errors. On a sample of 200 financial statements of public enterprises and related audit reports issued by the Audit Office of the Institutions in FBiH, we made a link between the Beneish M score model with its partial indicators (DSRI, GMI, AQI, SGI, DEPI, SGAI, LVGI, TATA) and four types of opinions: positive, opinion with distraction, negative and refraining from giving opinions. The research was conducted using descriptive statistics and an artificial neural network with the “scaled conjugate gradient backpropagation (trainscg)” algorithm for pattern recognition and classification. The research results show that it is possible on the basis of 8 partial indicators (DSRI, GMI, AQI, SGI, DEPI, SGAI, LVGI, TATA) i.e. 24 balance sheet position for their calculation, predict the auditor’s opinion on the quality of financial statements of public companies with an accuracy ranging between 98 and 100% in repeated procedures. The results of the research have their practical usefulness and can serve to researchers, creditors, customers, suppliers and state auditors in planning resources and priorities for performing financial audits at public companies in the FBiH.
Abstract COVID-19 is behind us, that is, it no longer poses a direct threat to the normal functioning of higher education. Nevertheless, the answers to the challenges in teaching, brought with it by COVID-19, have become an integral part of the curriculum of higher education institutions. When it comes to online teaching in accounting courses, additional creativity was expected from the teaching staff to successfully transfer knowledge. This was a particularly difficult challenge for those institutions and teaching staff who had not previously applied online teaching and online tools in the teaching process. The research was conducted on students of the Faculty of Economics of the University of Mostar (EF Mostar, FEM) and students of the Faculty of Economics of the University of Split (EF Split, FES), who took one or more accounting courses in the pandemic academic year 2020/2021 and partly in the academic year 2021/2022. The paper tried to offer answers to the questions about the degree of student satisfaction with online teaching, what are the advantages and disadvantages of this kind of teaching, and in which aspects there is room for improvement when considering the teaching of accounting courses in the context of online teaching.
Abstract Waste transport is just one of the segments in the solid municipal waste management. Throughout the entire waste life cycle, starting by generation of waste, via storing, collecting, transporting, recycling, treating and depositing, several different polluting substances are emitted. The solid waste transport, apropos, transporting vehicles emit into the air different pollution substances such as CO2, CO, NOx, NMVOC, PM, PAHs etc. These substances can present certain problems for human health and environment. The research subject of this study is the analysis of solid waste transportation within the Banja Luka region (B&H), from towns and municipalities belonging to the region and transporting their mixed municipal waste to the Banja Luka landfill. In the analysis, following parameters are included: distance to the landfill, type of vehicle used for the waste transportation, type of the engine, vehicle capacity and the number of tours during a year. The study estimates the emission of CO, NOx, NMVOC, and PM2.5 during one year using the listed parameters and by applying EMEP/EEA guidelines for estimating the emission of polluting substances into the air. The largest emission of polluting substances (CO, NOx, NMVOC and PM2.5) is from the oldest vehicles. The newest vehicles had a significantly lesser emission of these polluting substances into the air. The recommendation for decreasing the emission from the transportation vehicles is to organise the transfer-stations, procure new vehicles, optimise the collection routes and decrease the number of tours, as well as to better the usage of the vehicle capacity level.
Background: The VEPs provide an objective measure of brain function, analyzing integrity of visual processing. With patients affected with schizophrenia, the changes with the implementation of VEP are evident, such as symmetrical deceleration of the impulse and the continuance of latency, which points to a degenerative illness, suggesting the presence of optical neuritis or hemianopsia conjoined with mentioned intracranial illness. Objective: The aim of the study was to determine the correlation of positive and negative symptoms (PANSS scores) and P100 latency between patients with schizophrenia and patients with migraine headache according to gender and age. Visual evoked potentials (VEPs) were applied. Methods: The sample included 80 subjects: a) S group- 40 patients with schizophrenia (21 males; 19 females); b) H group-40 healthy subjects with migraine headache (10 males; 30 females). The study was conducted at the Department of Psychiatry and Neurology University Clinical Center Sarajevo. Results: Our research revealed positive correlation of the P100 latency and the PANSS score of negative symptoms, which means that the subjects of the observed group with a higher latency of the P100 wave of the entire visual field in both eyes have higher PANSS scores of negative symptoms. The correlation is significantly higher in female subjects (37% shared variance) than in male subjects (12% shared variance). All male subjects have a PANSS negative symptoms score of 17 or higher, while all female subjects have a PANSS negative symptoms score of less than 17 positive correlations were registered in P100 latency in left view field of both eyes and in P100 amplitude in the region of right eye (p=0.01) in comparation with left eye region (p=0.05) in patients with schizophrenia. Conclusion: Results imply that the cognitive impairment seen in schizophrenia is not just due to deficits in higher order aspects of cognition but also encompasses significant deficits in early sensory processing. Our study is useful to initiate new questions and recommendations for further studies, specifically on changes in the occipital lobe in the schizophrenic patient’s brain.
Motor vehicles are complex dynamic systems due to spatial vibratory displacements during movement, changes in the characteristics of components during life cycle, a large number of influences and disturbances, the occurrence of clearance, friction, hysteresis, etc. The mentioned dynamic phenomena, especially vibrations, cause fatigue of the driver and passengers, reduce the life cycle of the vehicle and its systems, etc. In the general case, the movement of motor vehicles is done on uneven roads (terrain) and curvilinear paths in flat roads (terrains). Oscillatory movements cause loading of vehicle parts, but they also negatively affect human health. Therefore, even in the design phase of the vehicle, special attention must be paid to the harmonization of the mutual movement of the vehicle subsystem, and in particular, the suspension system. Theoretical, experimental or combined methods can be used for this purpose, and it is very useful to have experimental results of vibration of the vehicle subsystems in real operational conditions. Therefore, it is very useful to have experimental results of vibration of vehicle subsystems in operational conditions. Bearing that in mind, the aim of this wpaper was to use the movement of FAP 1118, 4x4 wheel formula, in operational conditions (due to higher speeds - in road conditions) to define laboratory conditions for testing. This is made possible by registering and identifying statistical parameters of registered quantities.
The vehicle steering system is one of the most important systems on the vehicle, both in terms of safety and performance. Based on the geometry of the steering trapezoid, the geometry of the suspension system, the alignment angles of the wheels, as well as the characteristics of the tires, a mathematical model for the design of the formula student vehicle "Road Arrow" steering system was developed. Based on the dynamic state of the vehicle, the mathematical model provides information on the stress of the steering system, the torque on the steering wheel and the slip angles of the steered wheels. The mathematical model was developed using the MATLAB software, and validation of the results was performed by comparing the results with the ones obtained by simulations in MSC ADAMS. Analysing the obtained results, it is possible to conclude that the average value of relative error of the stress is approximately 15%, for slip angles of the steered wheels is approximately 7%, and the error for torque on the steering wheel is approximately 6%.
Abstract The paper explores the possibility of using the novel Deep Operator Networks (DeepONet) for forward analysis of numerically intensive and challenging multiphysics designs and optimizations of advanced materials and processes. As an important step towards that goal, DeepONet networks were devised and trained on GPUs to solve the Poisson equation (heat-conduction equation) with the spatially variable heat source and highly nonlinear stress distributions under plastic deformation with variable loads and material properties. Since DeepONet can learn the parametric solution of various phenomena and processes in science and engineering, it was found that a properly trained DeepONet can instantly and accurately inference thermal and mechanical solutions for new parametric inputs without re-training and transfer learning and several orders of magnitude faster than classical numerical methods.
Hepatozoon silvestris (Adeleorina: Hepatozoidae) is a recently described agent of feline hepatozoonosis. Although possibly emerging in Europe, this apicomplexan parasite is still largely unknown. Here, we provide insight into our current knowledge of the parasite's distribution, biology, and pathogenesis of the associated disease.
A study of the phytochemical and molecular characteristics of ten Micromeria and six Clinopodium taxa (family Lamiaceae) distributed in the Balkan Peninsula was carried out. The phytochemicals detected in essential oils by gas chromatography, mass spectrometry, and molecular data amplified fragment length polymorphism were used to study the taxonomic relationships among the taxa and the correlations between phytochemical and molecular data. STRUCTURE analysis revealed three genetic groups, while Bayesian Analysis of Population Structure grouped the studied taxa into 11 clusters nested in the groups obtained by STRUCTURE. Principal components analysis performed with the 21 most represented compounds in the essential oils yielded results that were partly consistent with those obtained by STRUCTURE and neighbour-joining analyses. However, their geographic distributions did not support the genetic grouping of the studied taxa and populations. The Mantel test showed a significant correlation between the phytochemical and genetic data (r = 0.421, p < 0.001). Genetic distance explained 17.8% of the phytochemical distance between populations. The current taxonomic position of several of the studied taxa is yet to be satisfactorily resolved, and further studies are needed. Such future research should include nuclear and plastid DNA sequences from a larger sample of populations and individuals.
We present different approach in teaching physics for high-school students for various branches of physics, such as thermodynamics, electromagnetism, etc. When we use term “different”, we want to offer complementary approach to the traditional one. This approach involves bringing everyday situations [1], such as drinking tea in a desert, making coffee, etc., to the physics classroom context without theoretical teaching with formulae, laws, and definitions in the beginning or opening of the class. The idea is to develop logical concepts to prepare students for theoretical teaching and introduce formulae to them in order to have a complete frame of specific physical phenomena. Some classes include practical demonstrations [2] where students immerse in discussion and spontaneously involve in growing logical concepts needed for better adoption of definitions, laws, and formulae [3].
We discuss the scope of accreditation presentation in certificates and annexes issued by NABs for calibration laboratories (accredited in accordance with ISO/IEC 17025 [1]) in accordance with ILAC P14:2020 [2], with specific requirements stated in clause 4.3 for expression of measurement uncertainty (expanded uncertainty) regarding the unit. Due to the close link between accreditation, metrology, and standardization, we consult BIPM documents [3] and discuss the practice in metrological institutes when it comes to expressions of expanded uncertainty in order to give another view and arguments on ILAC P14:2020 requirement for expanded uncertainty to be expressed only in terms of measurand's unit. We present our case for the quantity of temperature, in addition to some other physical quantities with similar cases as temperature.
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