Radiation-based local-regional therapies for hepatocellular carcinoma (HCC) have gained wide acceptance due to promising rates of tumor response, survival, and safety profiles. After treatment, it is important to assess tumor response to determine further management, patient prognosis, and endpoint outcomes for clinical trials. To standardize imaging interpretation and reporting of HCC response to local-regional treatment, a few imaging-based response assessment systems were developed. Two of them have emerged as the most used: the Liver Imaging Reporting and Data System (LI-RADS) Treatment Response Algorithm (LR-TRA) and the modified Response Evaluation Criteria in Solid Tumors (mRECIST). While these systems have been validated for the assessment of response to ablative locoregional therapies, assessment of response to radiation-based therapies can be challenged by persistent or evolving imaging features and is still an area of active research. Following the advances in technology and a better understanding of tumor biology that allowed for the increased application of radiation-based local-regional therapies for the treatment of HCC, research is still needed to address the limitations of current imaging criteria for assessing tumor response to these novel techniques. In this review, we describe radiation-based liver-directed treatment options, examine imaging criteria for assessing treatment response, discuss practical limitations and gaps in knowledge when applying these response criteria, and address future directions that may help to improve accuracy and outcomes when assessing response to radiation-based HCC treatment.

This paper primarily analyzes the classification of international organizations according to different criteria to see the specificity of the EU as a sui generis international organization. The authors specifically examine the legal order of the EU and the process of achieving full membership. They are interested in the EU accession process, particularly for countries in the Western Balkans like Bosnia and Herzegovina, which is covered by the Stabilization and Association Agreement. Candidate countries have access to various EU funds, which the authors analyze as pre-accession assistance. The study assesses Bosnia and Herzegovina’s status in European integration and delves into the use of IPA funds in the country, including its withdrawal, scope, and limitations. The authors emphasize the importance of IPA funds for Bosnia and Herzegovina.

High handgrip strength in men’s artistic gymnastics is crucial, mainly for improving performance and to potentially prevent injuries, as well as for the fact that gymnasts body movements are around immovable apparatuses (pommel horse, rings, parallel bars and high bar) for the extended period of time. Since there are not so many studies that have dealt with this topic and on actual competition, we have aimed to examine the handgrip strength influence on the competition result in elite male artistic gymnasts. The sample of participants were conducted of 37 elite male artistic gymnasts (8–21 years old), from 8 different countries as national team competitors at the International Competition “Laza Krstić and Marica Dželatović” held in Novi Sad, Serbia. Basic anthropometric measurements were included (body height, body weight and Body Mass Index (BMI)), along with training experience and handgrip strength measurement (both dominant and nondominant hand). Kolmogorov-Smirnov Z test (p < 0.05) was used for distribution normality, along with regression analysis with Model 1 (participants age, training experience, body height, body weight and BMI), Model 2 (Model 1 + dominant handgrip strength) and Model 3 (Model 1 + nondominant handgrip strength). SPSS v.20 was used for all statistical analysis. Our study have revealed that there is significant influence of all 3 Models on the parallel bars final result (p = 0.33; p = 0.49; p = 0.31, respectively), in terms of all set of variables, whereas body weight Beta scores (28.6%; 30.3%; 32.7%, respectively) moslty explains the results. Both dominant and nondominant handgrip strength are influential factors only on the parallel bars final result. Since both hands are contributing equally, bilateral training is necessary. In order to expand the knowledge on this topic and completely understand the influential factors, future studies are needed on this sample. Regardless of our main findings, our results should be taken with caution.

The primary aim of the paper is to conduct research on the personality traits in esport players and athletes, in addition to confirming differences in personality between the two examined groups. The research has been conducted on 67 (N=67) examinees, 30 of whom are semi-professional or professional esports players who participate in state-level and regional-level competitions. The remaining 37 examinees are the highest-ranked athletes in Bosnia and Herzegovina. T-test, a type of inferential statistic, has been used to determine statistical differences in disposition between the arithmetic means of the two groups, using the BFI-44 (a=0.78) measuring instrument. It has been anticipated that esports players would be ranked lower on Extraversion (E), Agreeableness (A), and Conscientiousness (C), but higher on the Neuroticism (N) and Openness (O) dimensions compared to athletes. The research indicates that four of the five hypotheses have been confirmed - on the scale of Extraversion (E) with significance levels of p=.000 (p<0.0001); Agreeableness (A) showing p=.002 (p<0.01); Neuroticism (N) showing p=.042 (p<0.05); and Conscientiousness (C) showing significance levels of p=.004 (p<0.01) The fifth hypothesis was not confirmed on this sample. The results gathered on this sample could significantly contribute to understanding the differences between esports players and athletes.