This article explores the options for establishing a legal framework for posthumous medical data donation (PMDD). This concept has not been discussed in legal scholarship to date at all. The paper is, therefore, a first legal study of PMDD, aiming to address the gap and shed light on the most significant legal issues that could affect this concept. The paper starts by looking at the protection of the deceased’s health records and medical data, finding that this protection in law is more extensive than the general protection of the deceased’s personal data, or the protection of post-mortem privacy as a concept. The paper then investigates key issues around ownership and succession of personal data, including medical and health-related data, and how these could affect PMDD and its legal framework.

During its 132-year production, the characteristics of Livno cheesechanged, first because of the transition from sheep to cow’s milk, or their mixture.Livno cheese is specific primarly due to the presence of a specific plant cover inmountain area, climatic conditions and milk of autochthonous sheep. The purposeof this work is to determine the fatty acid composition of Livno cheese, with specialreference to the contenct of bioactive components that have a positive effect onhuman health, and to tracking any changes in their content depending on thesampling or feeding period. For the production of Livno cheese, which was sampledafter 90 days of ripening at ambient conditions, sheep’s milk was used, mentioningthat the cow’s milk was added in proportion (80:20), which is commonly used in thetraditional production of this cheese. Samples were analyzed by gas chromatographyin As Vitas laboratory in Oslo Innovation Center, according to the proceduredescribed in Luna and al. (2005). A total of 24 fatty acids were determined during thethree sampling periods (July, August and September) In cheese samples, saturatedfatty acid content (SFAs) was higher in relation to monounsaturated(MUFAs) andpolyunsaturated (PUFAs) fatty acids. The fatty acid composition of the tested cheesesamples is specific, because it contains fatty acids which have been proven to havean extremely beneficial effect on human health.

Brucele u organizmu inficiranih životinja induciraju i humoralnii ćelijski imunološki odgovor. Humoralni imunološki odgovor se bazira na praćenjupojave specifičnih antitijela protiv glatkog lipopolisaharida (S-LPS) ćelijskemembrane brucela. Međutim kod goveda u dokazu specifičnih antitijela klasičnimserološkim metodama mogu se detetkovati antigene determinate za druge vrstemikroorganizama (unakrsna reaktivnost) kao što su: Escherichia coli 0:157, Yersiniaenterocolitica 0:9, Salmonella urban, Pseudomonas malthopilia i Pasteurellae. Cilj ovograda je utvrditi ćelijski imunološki odgovor koji se bazira na upotrebi pročišćenog istandardiziranog alergena, kojem je u potpunosti odstranjen lipopolisaharid te kaotakav ne dovodi do razvoja humoralnog imunološkog odgovora. Ukupno je ispitano16 goveda s područja Federacije Bosne i Hercegovine kod kojih je - Rose Bengaltestom ireakcijom vezivanja komplementa utvrđeno prisustvo specifičnih antitijelana brucelozu. Kožni test je izvođen prema uputama proizvođača. U testu je korištenbrucelin, ekstrakt B. melitensis B115 (Synbiotics Brucellergene OCB). Kod 14 govedaje nakon 72 sata od aplikacije utvrđeno zadebljanje kožnog nabora, dok kod dvagoveda nije izmjereno nikakvo zadebljanje. Razlog svakako treba tražiti u činjenicida su dva goveda imala pozitivan rezultat samo u Rose Bengal testu te se to možeprepisati unakrsnoj reakciji s antigeno srodnim mikroorganizmima.Kožni alergijski test nije preporučljiv kao samostalan dijagnostički alat jer nereaguju sve zaražene životinje, stoga ovaj test se ne može preporučiti kao individualnidijagnostički test ili u svrhu međunarodne trgovine. Međutim, zbog visokespecifičnosti i adekvatne osjetljivosti na nivou stada ili stada, može se preporučiti zanadzor stada / stada u područjima slobodnim od bruceloze.

Infection with Brucella results in the induction of both humoral andcellular immune responses. Humoral immune resposne is based on monitoringthe occurrence of specific antibodies against smooth lipopolysaccharide (S-LPS)of Brucella. However, in cattle, classical serological methods can detect antigenicdeterminants for other types of microorganisms (cross reactivity) such as Escherichiacoli 0:157, Yersinia enterocolitica 0:9, Salmonella urban, Pseudomonas malthopilia andPasteurella. The aim of our work was to determine the immunological responsebased on the use of standardized and purified allergen in which lypopolysaharid hasbeen removed and doesn’t induce humoral immune response. A total of 16 dairycattle previously tested positive using RBT (Rose Bengal test) and CFT (complementfixation test) were tested for confirmation with BST (brucelline skin test) accordingto the instructions of the producer. B. melitensis B115 (Synbiotics BrucellergeneOCB) was used in the test. 14 of 16 cattle reacted with skin thickening >1 mm after72 hours from the application of brucellin. 2 animals with no skin thickening orthickening <1mm also reacted negative in CFT. This outcome can be attributed tocross reactions with other antigens than Brucella that commonly occurs in RoseBengal test.Brucellin allergic skin test is not recommended as a standalone diagnostic toolbecause all infected animals do not react therefore this test cannot be recommendedas a self-sufficient diagnostic test or for the purpose of international trade.However, due to high specificity and adequate sensitivity at the herd level, it can berecommended for the control of herds in areas free of brucellosis.

Tokom svoje 132-godišnje proizvodnje, karakteristike Livanjskogsira su se mijenjale, najprije zbog prelaska sa ovčijeg na kravlje mlijeko, odnosnonjihovu mješavinu. Livanjski sir svoju specifičnost može zahvaliti, prije svega,prisustvu specifičnog biljnog pokrivača planinskog područja, klimatskim uvjetima imlijeku autohtone ovce pramenke. Cilj ovoga rada je odrediti masno-kiselinski sastavLivanjskog sira, sa posebnim osvrtom na sadržaj bioaktivnih komponenti koje imajupozitivan efekat po zdravlje ljudi, kao i na praćenje eventualnih promjena u njihovomsadržaju u ovisnosti o periodu uzorkovanja, odnosno hranidbe. Za proizvodnjuLivanjskog sira, koji je uzorkovan nakon 90 dana zrenja u ambijentalnim uslovima,korišteno je zbirno mlijeko ovaca, uz napomenu da je ovčijem mlijeku dodavanokravlje, u odnosu (80:20) koji se uobičajeno koristi u tradicionalnoj proizvodnjiovog sira. Uzorci su analizirani gasnim hromatografom u laboratoriji „As Vitas“Oslo Innovation Centre, prema proceduri opisanoj u radu Luna i saradnici (2005).Ukupno su određene 24 masne kiseline, kroz tri vremenska perioda uzorkovanja(juli, august i septembar). U uzorcima sira, sadržaj zasićenih masnih kiselina (SFA)bio je veći u odnosu na mononezasićene (MUFA) i polinezasićene (PUFA). Sastavmasnih kiselina ispitivanih uzoraka sira je specifičan, jer sadrži masne kiseline zakoje je dokazano da imaju izuzetno povoljan efekat po ljudsko zdravlje.

Animations are widely used in today’s science classrooms. Therefore it is very important to explore under which conditions animations are most effective. In earlier studies it has been generally shown that the effectiveness of instruction largely depends on management of cognitive load. The aim of the present study was to compare the effect of Physlet animations, printed sequences of selected animation frames and traditionally presented static pictures on understanding about lenses and levels of cognitive load. According to the results of a quasi-experiment that included forty nine high-school students, Physlet-based teaching generally leads to higher germane load and consequently to more effective learning than the traditional approach. Particularly high levels of germane load have been found for Physlet-based problems . These findings can be accounted for by the interactivity feature of Physlets.

Abstract A novel SERS-based molecular sensor for detection and quantification of copper(II) ions with very good specificity and selectivity is reported in this work. The sensing is enabled by the employment of a synthesized dipicolylamine-based ligand anchored onto plasmonic gold nanoparticles through the sulfur atom of the methylthio group. The interaction of the ligand with copper(II) ions is followed by changes in the spectral features associated with pyridine ring breathing, as indicated by quantum chemical calculations performed at the density functional level of theory, which are proportional to the copper(II) concentration. The detection of copper(II) was possible down to 5 × 10−8 M in water. The proposed molecular sensor was applied for the detection of copper(II) ions in white wine, with the ability to detect amounts of copper(II) in wine lower than the maximum recommended amount of 7.87 × 10−6 M (0.5 μg/mL), indicating that the proposed molecular sensor is of potential interest as a routine test for the control of the copper(II) content in wine during wine production and in the final product.

Aquaculture as an agricultural activity in our country is capable ofproducing large amounts of different types and categories of fish. Climate andgeographic characteristics of our country, the terrain and development of agriculturalproduction as well as compliance with the principle of “sustainable development”,the position and importance of fishery in a multipurpose water utilization, mustdetermine the direction of development of the future trout production. The mostimportant type of fish grown in the trout fisheries in BiH is the rainbow trout,Oncorhynchus mykiss (Walbaum, 1792). In addition to the fact that growing thistype of fish is attractive to many producers, considering the high yield potential,it is also characterized by a significant level of tolerance to varying microambientconditions of the environment. Given the importance of fish production in Bosniaand Herzegovina, which is one of the rare branches of food sector that has fulfilledthe international standards and criteria and secured access to the markets of the EUcountries, it is necessary to establish optimal conditions to ensure high productivityof salmonid fisheries. Studying the reproductive cycles can provide very preciseand significant results of the overall condition of the entire organism during thisvery complex physiological process and of the overall population in the respectiveecosystem.

Akvakultura kao poljoprivredna djelatnost u našoj zemlji je u stanjuproizvoditi velike količine ribe različitih vrsta i kategorija. Klimatske i geografskekarakteristike naše zemlje, njen reljef i razvoj poljoprivredne proizvodnje kao ipoštovanje principa „održivog razvoja”, mjesta i značaja ribarstva u višenamjenskomkorišćenju voda, moraju da određuju pravac razvoja proizvodnje pastrmki ubudućnosti. Najvažnija riblja vrsta koja se uzgaja u pastrmskim ribnjacima kodnas je kalifornijska pastrmka, Oncorhynchus mykiss (Walbaum, 1792). Osim što jegajenje ove vrste ribe privlačno za veliki broj proizvođača, s obzirom na mogućnostpostizanja visokih prinosa, nju odlikuje i značajna tolerantnost na variranjamikroambijentalnih uvjeta okoliša. S obzirom za značaj proizvodnje ribe u Bosni iHercegovini, koja je jedna od rijetkih grana prehrambenog sektora koja je uspjelaispuniti međunarodne standarde i postavljene kriterije te osigurati izlazak na tržištezemalja Europske unije, neophodno je ustanoviti optimalne uslove koji obezbjeđujuvisoku produktivnost salmonidnog gospodarstva. Proučavanje reproduktivnogciklusa može dati vrlo precizne i značajne rezultate o stanju organizma za vrijemeovog vrlo složenog fiziološkog procesa, kao i populacije u datom ekosistemu.

PurposeThe purpose of this paper is to draw on dynamic capability view and contingency theory to clarify the nature of the effect of environmental turbulence on the relationships between firm’s both product and process innovations and business performance.Design/methodology/approachThe authors developed and empirically tested two structural models using structural equation modeling approach. The first model deals with both product and process innovations as the mediators between environmental turbulence and business performance. The second model considers the moderating effect of environmental turbulence between innovation and business performance.FindingsThe findings show that environmental turbulence does not moderate the relationship between innovation and business performance. The authors have found a clear role of environmental turbulence in boosting innovation rather than moderating the relationship between innovation and performance.Research limitations/implicationsThe data set is a cross-section of heterogeneous firms regarding the industry.Practical implicationsManagers should be aware of the importance of the innovation for the environmental turbulence and dynamism counteracting. The results imply a negative influence of environmental turbulence on business performance. However, with the innovation in the equation, this influence can be positive, because it boosts firms to innovate and though to achieve better business performance.Originality/valueIt contributes the management and innovation research and practice through offering insights into the role of environmental turbulence in product innovation, process innovation as well as organizational business performance through comprehensive analysis of mediation and moderation effects between the observed constructs.

Pneumonia is the leading infectious cause of death worldwide. While inflammation is critically important in host response to microbial invasion, exaggerated inflammation can damage the lungs, contributing to respiratory failure and mortality. Corticosteroids are effective in reducing inflammation and can also cause immune suppression. Presently, clinicians are unable to reliably distinguish between exaggerated and appropriate immune response and thus cannot rapidly identify patients most likely to benefit from adjunctive corticosteroids. In this review, we propose a biomarker-guided, precision medicine approach to corticosteroid treatment, aimed to give these medications at appropriate dose and time and only to patients who have exaggerated inflammation.

Global dynamic results are obtained for families of competitive systems of difference equations of the form

Recreational football has been shown to be an effective health-promoting activity, but it is still unclear how changes in game formats affect external and internal load. The aim of this study was therefore to evaluate the effect of area per player in recreational small-sided football games. Ten recreational active male football participants (mean±standard deviation, age: 20.1±1.1 years; height: 182.2±7.4 cm; body mass: 75.9±9.8 kg) completed two sessions comprising 2x20 min of 5v5 football with 80 and 60 m2 per player, during which heart rate (HR) and movement pattern were measured. In 80 m2, mean HR (167±9 vs. 160±10 b.p.m., P<0.001, ES=0.70) and peak HR (192±8 vs. 188±9 b.p.m., P=0.041, ES=0.50) were significantly higher than in 60 m2. Percentage playing time with HR >90%HRpeak was higher in 80 m2 than 60 m2 (45±14 vs. 29±16%, P=0.004, ES=1.07). Moreover, a higher number of sprints (8.0±4.8 vs. 3.0±1.3, P=0.014, ES=1.41) and a greater distance in the highest speed zones (>13, >16 and >20 km·h1) were covered in 80 m2 than 60 m2. Peak running speed was also higher in 80 m2 (24.3±1.7 vs. 22.3±1.4 km·h-1, P=0.011, ES=1.27), whereas no statistically significant differences were found in total distance covered, player load, or the acceleration-deceleration profiles. In conclusion, the internal and external loading was higher for recreationally active male football players when playing on a pitch with 80 m2 area per player compared to 60 m2.