Haemonchus contortus is a globally significant parasitic nematode in ruminants, with widespread resistance to benzimidazole due to its excessive and prolonged use. Given the extensive use of benzimidazole anthelmintics in Bosnia and Herzegovina, we hypothesized that resistance is prevalent. The aim of this study was to identify the presence of anthelmintic resistance to benzimidazole in H. contortus from naturally infected sheep, goats and cattle in Bosnia and Herzegovina through the detection of the Phe/Tyr polymorphism in the amino acid at position 200 of the β-tubulin protein. From 19 locations in Bosnia and Herzegovina, a total of 83 adult H. contortus were collected from the abomasum of ruminants. Among these, 45 H. contortus specimens were isolated from sheep, 19 from goats and 19 from cattle. Results showed that 77.8% of H. contortus in sheep exhibited homozygous resistant genotypes at position 200 of the β-tubulin gene, with 15.5% being heterozygous. In goats, all tested H. contortus (100%) were homozygous resistant, and no heterozygous resistant or homozygous sensitive genotypes were found. Cattle had 94.7% homozygous resistant H. contortus, with no heterozygous resistant genotypes detected. In H. contortus from sheep and cattle, 6.7% and 5.3%, respectively, displayed homozygous sensitive genotypes. This study, for the first time, highlights the presence of a resistant population of H. contortus in sheep, goats and cattle in Bosnia and Herzegovina, using the rt-qPCR method. The resistance likely spread from sheep or goats to cattle, facilitated by shared pastures and the practice of transhumance, indicating a widespread and growing issue of anthelmintic resistance.

Nowadays, in order to maintain cleanliness in our houses, as well as to maintain personal hygiene, numerous chemical agents are used every day. Dishwashing detergents are used the most, followed by laundry detergents, various soaps and hair sham?poos, and not infrequently descaling agents, for cleaning ovens, unclogging drainage and sewage pipes, neutralizing unpleasant odours, etc. Although their number is growing day by day, most people do not realize the consequences, or at least not enough, and especially not about their potentially toxic effects. In fact, a great deal of the population do not consider household chemicals a particular problem, which is true, if they are used in the pre?scribed manner. However, the fact that these agents can cause harmful effects in humans and animals, and even participate in environmental pollution, is more than a sufficient reason to pay more attention to these agents, that is, to talk about them more and obtain more information for that matter. Particularly since there are authors who believe that some of the mentioned agents can even cause cancer, asthma or birth defects, i.e. infertility. Household chemicals can be divided in several ways, and one of the classifications is the one made according to the place of use. According to this division, the products we use every day at home can be roughly divided into those used for cleaning and maintaining hygiene in kitch?ens, used for the same purposes in bathrooms (including those used for personal hygiene ), and the products used in rooms and on terraces (flower protection).

Gastrointestinal nematode (GIN) infections remain one of the most prevalent and important issue affecting ruminants worldwide. Until date, the majority of GIN control has relied on the administra-tion of chemical anthelmintic medications on a regular basis, in recent years, the problem of anthel-mintic resistance has reached new heights where it can no longer be ignored as a major issue in the control of parasites of livestock. Anthelmintics are generally used at farmers' discretion, with no restrictions to access to commercially available drugs and without any assistance from veterinarians. Thus, inadequate use of anthelmintics is not rare, animals are often treated excessively, interfering with production, accelerating selection of resistant parasites, and posing significant problems for the ruminant industry. The unusually high frequency of multi-drug resistance (MDR) in sheep and goat nematodes threatens the sustainability of small-ruminant enterprises in several parts of the world. Although resistance in horses and cattle nematodes has not yet reached the levels reported in small ruminants, data shows that resistance issues, particularly MDR worms, are rising in these hosts. Both innovative non-chemical parasite control methods and molecular tests capable of detecting resistant worms are urgently needed. Keywords: Anthelmintics; Multidrug resistance; Gastrointestinal nematodes; Ruminants; Preva-lence

The European Union permitted 6 antimicrobial agents that can be used in laying hens. These are colistin, tyrosine, neomycin, oxytetracycline, chlortetracycline, and erythromycin. Antimicrobial drugs are used today primarily for the prevention and treatment of diseases in poultry and often (not in the EU) to stimulate growth. Because these drugs are often used irrationally, there are good chances that their residues will be found not only in poultry meat but also in the eggs within a certain period after the termination of treatment. In addition to the administration of authorised VMPs, the residues in eggs can be the result of erroneously applied medicated food, the contamination of the food with some antimicrobial drug in the mixing unit, as well as ?extra-label? use of drugs in poultry. The antimicrobial agents are distributed in the body and deposited in the eggs, mainly in the yolk where they persist longer than in the albumen. Drugs that are poorly absorbed from the gastrointestinal tract (aminoglycosides, aminocyclitols, polymyxins) cannot be detected in the eggs, while the residues of some antimicrobial drugs can be detected for up to two months (chloramphenicol) after the last treatment. The rational use of drugs in veterinary medicine has manifold significance. When using drugs only when they are really necessary (indicated), in the right dose and route of administration, the potential damage can be reduced and efficiency increased, while the risk of microorganism resistance development would be significantly decreased. All of this becomes more important when these drugs are used in food animals.

Poultry meat production is one of the most dynamic sectors in agriculture, recording the quickest growth in the food industry, while egg production has shown strong growth in the last twenty years. Combined with meat production, it is achieving the highest growth when it comes to meeting protein needs for the global population. In economic terms, coccidiosis is one of the most significant poultry diseases. Effective application of coccidiostats in poultry feed has been playing a key role in development of commercial poultry production for more than 50 years. The aim of this research was to estimate occurrence and residue concentrations of coccidiostats in table eggs, poultry liver and meat, available on the market in Bosnia and Herzegovina (B&H). Residues of lasalocid were found in table eggs, while residues of nicarbazin, maduramicin and diclazuril were detected in broiler meat and liver.

Procjena botaničkog sastava pašnjaka na različitim područjima s posebnim osvrtom na udjele terpena, koji osim učinka na terpenski profil arome mesa preživača mogu imati i potencijalni imunomodulacijski učinak, od bitnog je interesa suvremenog ovčarstva u R. Hrvatskoj. U istraživanjima u okviru ovog rada, pokazano je da ljekovite svojte bogate terpenima poput gospine trave (Hypericum perforatum L.), stolisnika (Achillea millefolium L.) i matičnjaka (Melissa officinalis L.) zbog statistički značajno veće učestalosti, gustoće i pokrovnosti na pašnjacima Velike Crkvine, u odnosu na pašnjake u Kvarte, potencijalno utječu na bolji imunosni status ovaca. Stoga su u ovom radu dobiveni rezultati znanstvena preporuka za daljnju procjenu biljnog sastava pašnjaka u Velikoj Crkvini tijekom istraživanja HRZZ projekta IP-2016-06-3685 u cilju postizanja dodatnih saznanja o učinku terpena na zdravlje i aroma sastav janjećeg mesa i to sve u svrhu proizvodnje inovativnih funkcionalnih proizvoda od janjećeg mesa.

Akvakultura kao poljoprivredna djelatnost u našoj zemlji je u stanjuproizvoditi velike količine ribe različitih vrsta i kategorija. Klimatske i geografskekarakteristike naše zemlje, njen reljef i razvoj poljoprivredne proizvodnje kao ipoštovanje principa „održivog razvoja”, mjesta i značaja ribarstva u višenamjenskomkorišćenju voda, moraju da određuju pravac razvoja proizvodnje pastrmki ubudućnosti. Najvažnija riblja vrsta koja se uzgaja u pastrmskim ribnjacima kodnas je kalifornijska pastrmka, Oncorhynchus mykiss (Walbaum, 1792). Osim što jegajenje ove vrste ribe privlačno za veliki broj proizvođača, s obzirom na mogućnostpostizanja visokih prinosa, nju odlikuje i značajna tolerantnost na variranjamikroambijentalnih uvjeta okoliša. S obzirom za značaj proizvodnje ribe u Bosni iHercegovini, koja je jedna od rijetkih grana prehrambenog sektora koja je uspjelaispuniti međunarodne standarde i postavljene kriterije te osigurati izlazak na tržištezemalja Europske unije, neophodno je ustanoviti optimalne uslove koji obezbjeđujuvisoku produktivnost salmonidnog gospodarstva. Proučavanje reproduktivnogciklusa može dati vrlo precizne i značajne rezultate o stanju organizma za vrijemeovog vrlo složenog fiziološkog procesa, kao i populacije u datom ekosistemu.

Aquaculture as an agricultural activity in our country is capable ofproducing large amounts of different types and categories of fish. Climate andgeographic characteristics of our country, the terrain and development of agriculturalproduction as well as compliance with the principle of “sustainable development”,the position and importance of fishery in a multipurpose water utilization, mustdetermine the direction of development of the future trout production. The mostimportant type of fish grown in the trout fisheries in BiH is the rainbow trout,Oncorhynchus mykiss (Walbaum, 1792). In addition to the fact that growing thistype of fish is attractive to many producers, considering the high yield potential,it is also characterized by a significant level of tolerance to varying microambientconditions of the environment. Given the importance of fish production in Bosniaand Herzegovina, which is one of the rare branches of food sector that has fulfilledthe international standards and criteria and secured access to the markets of the EUcountries, it is necessary to establish optimal conditions to ensure high productivityof salmonid fisheries. Studying the reproductive cycles can provide very preciseand significant results of the overall condition of the entire organism during thisvery complex physiological process and of the overall population in the respectiveecosystem.