Background: While the COVID-19 pandemic continues to spread globally, more and more evidences are collected about the presence of psychiatric and neurological manifestations and symptoms associated with this disease. Objective: The aim of this short communication is to present some of psychological consequences and neurological disorders associated with the SARS-CoV-2 infections, Methods: This is cross-sectional study according to psychosocial and neurological manifestations caused by COVID-19 infections published in papers deposited in most influential on-line databases. Results and Discussion: The results show presence of central and peripheral nervous system manifestations related to coronavirus. Neurological manifestations, or NeuroCOVID, are part of the COVID-19 clinical picture, but questions remain regarding the frequency and severity of central nervous system symptoms, the mechanism of action underlying neurological symptoms, and the relationship of symptoms with the course and severity of COVID-19. Conclusion: The review of the published papers shows that although more and more papers are reporting neurological and psyhiatric manifestations associated with COVID-19, many items remain unclear and this uncertainty calls for a global action that requires close co-ordination and open-data sharing between hospitals, academic and public health institutions and the fast establishment of harmonised research priorities to face actual and longterm the NeuroCOVID-19 complications and psychological consequences.
Introduction: Anomalous innervations of the extremities are common and influence the interpretation of electrophysiologic studies in normal subjects and those with peripheral nerve lesions. The aim of this study was to describe the most common innervation anomalies in upper and lower extremities and to point out their clinical repercussions. Methods: Article has an analytical character and review of literature, including some personal articles. Results and Discussion: Double innervation and communications among nerves are causes of anomalies of innervation of the skin and muscles. The fact of communications of fibers among nerves is better called “nerve communication” than “nerve anastomosis”. Anomalous innervations of the upper and lower extremities are, therefore, common and influence on the interpretation of neurophysiological parameters during electromyoneurography. Namely, in the course of an electrodiagnostic investigation of a peripheral nerve lesion, the examiner may be confronted with unexpected findings in contradiction with the clinical picture. In this review, a description is given of the most common innervation anomalies in upper and lower extremities: median to ulnar nerve communication (Martin-Gruber anastomosis); ulnar to median nerve communication (Marinacci anastomosis/MA); variations in the innervation of intrinsic muscles of the hand (Riche-Cannieu anastomosis; Berrettini anastomosis); accessory deep peroneal nerve; and tibial to peroneal nerve communication. Conclusion: As anomalous innervations of the extremities are common and influence the interpretation of electrophysiological studies in normal subjests and those with peripheral nerve lesions, detailed anatomical knowledge is essential for accurate interpretation of physical examination, electrophysiological findings, diagnosis, prognosis and reducing the risk of iatrogenic injuries during surgical procedures. If these variations are not given due regard, errors and other consequences will be inevitable.
This chapter provides important empirical evidence to support the role of individual knowledge management processes and separate innovation types within firms. Specifically, knowledge acquisition and knowledge application are analyzed and empirically tested in relation to product and process innovation as well as business performance. The results support the direct impact of product and process innovation on business performance. In addition, the results show the indirect effect of knowledge acquisition and knowledge application on firm business performance through product and process innovation.
Background: It is clear that in developed countries more women die annually from ovarian cancer than from all other gynecologic malignancies combined. Objective: The aim of this article is to analyze current possibilities and propose adequate measures which can help the development of effective screening methods/assays for the early detection of epithelial ovarian cancer. Results and Discussion: This article updates the status of ovarian cancer screening and addresses most relevant studies published during the last five years. The developments that followed the review are best summarized in reference to the screening tests, target populations and newly published trials. The possible role of 3D ultrasound technology, especially 3D power Doppler imaging, in early and accurate detection of ovarian malignancy is discussed. We described our new ovarian cancer screening trial, which started in January 2001. Improvements in ultrasound technology such as 3D volume acquisition and 3D power Doppler imaging may have clinical utility in a more reliable identification of an abnormal ovarian vascularity and architecture. 3D volume acquisition allows for careful evaluation of the internal surfaces of cyst walls for excrescences otherwise not appreciated by 2D ultrasound. Conclusion: While the addition of 3D power Doppler provides a new tool for measuring the quality of ovarian tumor angiogenesis, improving accurate diagnosis of ovarian malignancies, its clinical value for the early detection of ovarian carcinoma has yet to be determined.
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