Introduction. Acute rhinosinusitis (ARS) encompasses a heterogeneous group of inflammatory disorders affecting nasal mucosa and paranasal sinuses. Rhinosinusitis is the most common condition in the United States. It is estimated that over 30 million people annually visit the doctor due to this condition, while every sixth adult suffers from ARS. Among all ARS complications, over 91% are orbital complications (OC) with an average prevalence of 6% and a higher incidence in children compared to adults. Case report. Twelve-year-old boy, accompanied by his mother, was urgently referred to the Department of Otorhinolaryngology at the University Hospital in Foca due to a sudden red and painful left periorbital edema, pain in the left eye and a fever reaching 38.5ºC. After laboratory and CT scan diagnostics, an ophthalmologic examination and inpatient clinical findings after 36 hours of parenteral triple antibiotic therapy, the patient was referred to a tertiary-type institution for further treatment. The same procedure was performed conservatively during the hospitalization within 6 days. Conclusion. The initial treatment of orbital complications in children is conservative. Treatment should be started empirically, using triple antibiotic therapy. The choice of antibiotics and treatment protocols among pediatric population have not been agreed yet. If 36-48 hours after the beginning of the conservative treatment, there is lack of the clinical response, surgical treatment is absolutely indicated, regardless of the stage of orbital complication.

Introduction/Objective. Malocclusions are one of the most frequent disorders in dentistry, and pose a risk for the onset of caries and periodontal diseases. Fixed orthodontic treatment solves the problem of malocclusions; however, it requires simultaneous cooperation of the patients, parents, and dentists involved. The objective of this study is to examine the effects of fixed orthodontic therapy on the Streptococcus mutans and Lactobacillus spp. bacteria in saliva, the pH value, and buffering capacity of saliva. Methods. The research was carried out at the Faculty of Medicine in Foca, Department of Dentistry. The study included 100 respondents, aged 13 to 17 years. The respondents were divided into two groups: the study group (respondents wearing fixed braces) and the control group (respondents not subjected to fixed braces therapy). Saliva samples were taken from the respondents four, 12, and 18 weeks after the start of the orthodontic therapy. The study used the bacteria caries risk test (CRT) and CRT buffer (Ivoclar Vivadent). Results. The study showed an increased number of bacteria in saliva of the respondents during all three follow-up periods (χ2 test, p = 0.001). The largest numbers of the Streptococcus mutans and Lactobacillus spp. bacteria were found in week 12 of the therapy. Saliva pH value and buffering capacity of saliva increased statistically significantly in week 12 of the therapy (χ2 test, p = 0.001). Conclusion. Oral conditions in patients changed during the fixed orthodontic therapy: the number of bacteria increased, the pH value and buffering capacity of saliva changed. It was necessary to use preventive measures in order to avoid complications during the fixed orthodontic appliances therapy.

Introduction. Decreased salivary flow is frequently associated with numerous diseases such as diabetes mellitus and may lead to numerous oral diseases. The aim of this study was to compare salivary flow rate and oral health status in type 2 diabetics and healthy controls. Material and methods. The study involved 90 patients, divided into the three groups: 30 with well controlled (HbA1c<9%), 30 will poorly controlled (HbA1c?9%) diabetes and 30 healthy subjects. The following clinical parameters were determined: decayed, missing and filled teeth (DMFT); plaque index (PI), sulcus bleeding index (SBI), probing pocket depth (PPD) and clinical attachment level (CAL). Culture of Candida spp. specimens were obtained from tongue dorsum and inoculated into Sabouraud Dextrose Agar. Saliva was collected using ?a spit technique?. Results. Highest mean of unstimulated salivary flow was in healthy subjects; however significant difference between groups was not observed. Stimulated salivary flow results indicate significant reduction in diabetics as well as significant relation between metabolic control and salivary flow. Unstimulated and stimulated salivary flows were negatively and significantly correlated with periodontal parameters and DMFT. Conclusion. The present findings indicate that decreased salivary flow rate could have a significant impact on oral health status in type 2 diabetics.

Many of medicaments used historically in root canal treatment have been shown to be cytotoxic. Paraformaldehid agents (such as Toxavit and Depulpin) are used to devitalize inflamed pulp when local anesthesia is ineffective. The misuse of pulp devitalizing agents may cause damage to gingiva and alveolar bone. This case report demonstrates complications arising after application of paraformaldehyde containing paste, necrosis of the gingiva and alveolar cortical bone, which resulted in great loss of supporting bone. Surgical intervention was required wherein necrotic bone was removed and bone defect was filled with xenograft of bovine origin. After three months endodontic treatment was performed. After the treatment, the patient?s complaints were resolved. The use of paraformaldehyde-based agents during endodontic therapy requires special caution.

Purpose: Change of direction speed (CODS) and reactive agility (RAG) are important qualities in futsal, but studies rarely examined the predictors of these conditioning capacities in players of advanced level. This study aimed to evaluate predictive validity of certain anthropometric and conditioning capacities in evaluation of futsal specific CODS and RAG in top-level players. Methods: The sample comprised 54 male players from Croatia and Bosnia and Herzegovina, members of teams competing at the highest national rank, including national champions for the 2017–2018 competitive season in both countries. The variables comprised set of predictors (body mass, body height, triceps skinfold, reactive strength index [RSI], sprint 10 m [S10M], and broad jump [BJ]; and four criteria: futsal specific CODS and RAG, performed with and without dribbling (CODS_D, CODS_WD, RAG_D, RAG_WD). To identify the association between variables Pearson’s correlation and multiple regressions were calculated. Results: Observed predictors explained statistically significant (p < 0.05) percentage of variance for all four criteria (Rsq: 0.28, 0.30, 0.23 and 0.25, for CODS_WD, CODS_D, RAG_WD, RAG_D, respectively). Body mass was significant predictor for all criteria (Beta: 0.35–0.51), with poorer performances in heavier players. In both performances which involved dribbling, significant predictors was RSI (Beta: −0.27 and −0.31 for CODS_D and RAG_D, respectively), with superior performances in players with better RSI. The S10M and BJ were not identified as being significantly correlated to studied RAG and CODS performances. Conclusion: Study confirmed specific influence of studied predictors of futsal specific CODS and RAG with consistent negative influence of body mass on studied performances. Almost certainly this can be explained by specifics of RAG and CODS execution. Specifically, tests are performed over relatively small distances, with several changes of direction, which clearly mimic the futsal specific performances. Although sprint performance is often observed as important determinant of CODS and RAG, herein we did not confirm its predictive validity in explanation of futsal specific CODS and RAG. Future studies should evaluate other potentially important predictors of these capacities in futsal.

Objective – The aim of the paper is to present a rare and complex congenital heart defect (CHD), congenitally corrected transposition of the great arteries of the heart (ccTGA) with associated anomalies, including ventricular septal defect (VSD), valvular and subvalvular pulmonary stenosis, dysplasia of the tricuspid valve, and atrial septal defect (ASD) with first-degree atrioventricular block, which was diagnosed, monitored and successfully treated with heart surgery in an infant. Case Report – A female infant was born with 3350 grams in weight, 50 cm in length, oxygen saturation of 98%, and heart rate of 170 beats per minute. The antenatal and perinatal period was normal. CHD was verified by ultrasound at the age of 3 days. Angiotensin-converting-enzyme inhibitors (ACE inhibitors) and diuretics were introduced in therapy after one month. Cardiac surgery (Senning-Rastelli procedure with placement of an 18-mm Contegra conduit) was performed at the age of 9 months. After the operation, the infant was stable on therapy with diuretics, antiaggregants, beta blockers, and antianemic therapy with vitamin D in prophylaxis. Conclusion – ccTGA with associated anomalies is a rare, life-threatening, congenital heart disease. After birth it demands correct diagnosis, adequate follow-up, and cardiac surgery in infancy.

Abstract A synthesis of an industrial utility system considering cogeneration options together with heat exchanger network synthesis has been developed. It consists of boilers at different temperature and pressure levels, steam turbines, condensers, cooling tower, deaerator and a heat exchanger network system, connecting the utility system with the process heat and electricity requirements. A mixed-integer nonlinear programming (MINLP) model was used for synthesis. A sensitivity analysis has been performed considering the price ratio of natural gas to electricity, while also estimating primary energy consumption and GHG emissions. The results indicate that the cogeneration is economically viable at different ratios of natural gas and electricity price. In addition, the sensitivity analysis shows the relationship between cogeneration and electricity purchase for obtaining the minimal primary energy consumption and consequently to reduce GHG emissions.

Abstract To comply with the outcomes of the Climate Change Conference in Paris (COP 21), the ever-growing greenhouse gas (GHG) emissions has to be drastically reduced. With the soaring growth rates of GHG emissions in the aviation sector, the need for a near zero-net greenhouse emission alternative is essential. The novel concept of the Power-to-Jet pathway directly utilizes renewable electricity, carbon dioxide and water to synthesize a sustainable kerosene fuel that chemically resembles the one produced from fossil sources, having ‘Drop-in’ capability allowing the use and distribution within existing architectures. In the Power-to-Jet process, hydrogen is produced via water electrolysis. Captured CO2 (from rich point sources) then reacts with hydrogen to produce the intermediate methanol, before being upgraded to the final synthetic jet fuel along with by-products (Schmidt et al., 2012). With fluctuating electricity inputs due to the variability in photovoltaic and wind power generation, the process units within the Power-to-Jet process have to be adjusted at each time-instant to satisfy the production constraints. To find the best operating strategy for these fluctuating conditions, dynamic models are needed. In this work, we will propose a model that describes the dynamic behaviour of the carbon capture section in the Power-to-Jet process. Several dynamic scenarios can be introduced for the carbon capture rate by altering the lean solvent concentration, flue gas flow rates and re-boiler duty. The dynamic information obtained from the simulations (such as: Open loop gain, time constants and dead time) can be used to device an appropriate control scheme under varying electricity inputs, while satisfying all operational constraints.