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A. Prtina, Nela Rašeta Simović, Tatjana Milivojac, M. Vujnić, M. Grabež, D. Djuric, M. Stojiljković, Valentina Soldat Stanković et al.

Psoriasis is an autoimmune and inflammatory skin disease. Psoriatic patients express higher levels of plasma homocysteine (Hcy) concentration and pro-inflammatory mediators than healthy people; this is frequently associated with vitamin D deficiency. The aim of this clinical study was to investigate the effects of high doses of vitamin D supplementation on the parameters of Hcy metabolism and cytokines in sera of psoriatic patients. This prospective study was conducted on 40 psoriatic patients who had the vitamin D deficiency. All patients received vitamin D 5000 IU/day for three months. Clinical and biochemical measurements were taken at baseline and at follow up (3 months). The results showed that the severity of clinical features, measured by the psoriasis area severity index (PASI) score, were considerably improved in patients after vitamin D supplementation. After vitamin D supplementation, most of the patients (n = 25 or 62.5%) had mild clinical form (p < 0.001). After twelve weeks of intervention period, there were significant increases in vitamin D and B12 serum levels in comparison to the levels that had been measured at the beginning of the study (56.77 ± 14.66 nmol/L and 301.08 ± 95.02 pg/mL vs. 103.85 ± 32.20 nmol/L and 362.81 ± 118.56 pg/mL, respectively; p < 0.001). Moreover, serum levels of Hcy and folate were significantly lower at the end of the study in comparison with the initial levels (12.45 ± 1.92 µmol/L and 8.01 ± 3.88 mg/mL vs. 10.38 ± 1.66 µmol/L and 6.27 ± 2.60 mg/mL, respectively). High doses of vitamin D supplementation led to a significant decrease in pro-inflammatory cytokines (IFN-ɤ, TNF-α, IL-1β, IL-6, IL-8, and IL-17) and high-sensitivity C-reactive protein (hsCRP), whereas the production of anti-inflammatory cytokines (IL-10, IL-5) was up-regulated. In conclusion, supplementation with high doses of vitamin D could be one of the possible preventive and therapeutic measures to reduce systemic inflammation in psoriatic patients.

Irena Martinis, A. Vrca, M. Bevanda, Sanja Botić-Štefanec, Jasna Bađak, Dinka Kušter, Tatjana Suttil, M. Lasić et al.

Jun Zeng, Jinlong Sun, Guan Gui, B. Adebisi, T. Ohtsuki, H. Gačanin, H. Sari

In this paper, a channel state information (CSI) feedback method is proposed based on deep transfer learning (DTL). The proposed method addresses the problem of high training cost of downlink CSI feedback network in frequency division duplexing (FDD) massive multiple-input multiple-output (MIMO) systems. In particular, we obtain the models of different wireless channel environments at low training cost by fine-tuning the pre-trained model with a relatively small number of samples. In addition, the effects of different layers on training cost and model performance are discussed. Furthermore, a model-agnostic meta-learning (MAML)-based method is proposed to solve the problem associated with large number of samples of a wireless channel environment required to train a deep neural network (DNN) as a pre-trained model. Our results show that the performance of the DTL-based method is comparable with that of the DNN trained with a large number of samples, which demonstrates the effectiveness and superiority of the proposed method. At the same time, although there is a certain performance loss compared with the DTL-based method, the MAML-based method shows good performance in terms of the normalized mean square error (NMSE).

Yuzhi Zhou, Jinlong Sun, Jie Yang, Guan Gui, H. Gačanin, F. Adachi

The development of the internet of things (IoT) and smart cities, combined with the widespread usage of cooperative or independent air traffic surveillance systems such as automatic dependent surveillance-broadcast (ADS-B) bring about novel deployment paradigms in air-ground integrated vehicular net-works (AGVN). However, compared with the evolutional physical layer advancing, the communication protocols such as TCP/IP protocol, which are listed on the top of communication protocol stacks, have relatively constricted developments due to their fixed frameworks. The most obvious manifestation of this trend is that these protocols can hardly extend interfaces to maximize the benefits brought by bottom layer upgrades. In view of the above problems, in this paper, we propose a novel handover strategy based on side information of the ADS- B for AG VN. Firstly, a practical scheme of combination between TCP/IP protocol and ADS-B, which is implemented in the Network simulation, version-3 (ns-3), is proposed to adapt the AGVN handover tasks. Secondly, the configuration, timing sequence and parameters, as well as hand over strategies of the scheme are proposed in detail with the modules called by ns-3 simulator. Finally, the experimental results are provided to validate the handover strategies.

Wenjuan Shi, Yanjing Sun, Miao Liu, Hua Xu, Guan Gui, T. Ohtsuki, B. Adebisi, H. Gačanin et al.

This paper proposes an unmanned aerial vehicle (UAV)-aided full-duplex non-orthogonal multiple access (FD-NOMA) method to improve spectrum efficiency. Here, UAV is utilized to partially relay uplink data and achieve channel differentiation. Successive interference cancellation algorithm is used to eliminate the interference from different directions in FD-NOMA systems. Firstly, a joint optimization problem is formulated for the uplink and downlink resource allocation of transceivers and UAV relay. The receiver determination is performed using an access-priority method. Based on the results of the receiver determination, the initial power of ground users (GUs), UAV, and base station is calculated. According to the minimum sum of the uplink transmission power, the Hungarian algorithm is utilized to pair the users. Secondly, the subchannels are assigned to the paired GUs and the UAV by a message-passing algorithm. Finally, the transmission power of the GUs and the UAV is jointly fine-tuned using the proposed access control methods. Simulation results confirm that the proposed method achieves higher performance than state-of-the-art orthogonal frequency division multiple-access method in terms of spectrum efficiency, energy efficiency, and access ratio of the ground users.

12th Days of the Academy of Medical Sciences of Bosnia and Herzegovina (AMNuBiH) this year were organized together with the International Academy of Sciences and Arts in Bosnia and Herzegovina in Sarajevo on December 4, 2021. The title of the symposium was “Scientometry, Citation, Plagiarism and Predatory in Scientific Publishing”. Experiences in the scientific area covered by title of this conference were presented by some of the most influential scientists from Bosnia and Herzegovina, who are included between 2% of authors in the Stanford scientometric list, which was published in October 2021 in the journal Biology Plos. Some of the authors are former or current Editors-in-Chiefs of indexed biomedical journals in Bosnia and Herzegovina, Croatia, North Macedonia (Izet Masic, Asim Kurjak, Doncho Donev, Osman Sinanovic). Also, Sylwia Ufnalska and Izet Masic are or were members of the European Association of Science Editors (EASE) and they have great experiences about the topic of this conference. Science that analyzes scientific papers and their citation in the scientific journals – called scientometrics – day by day has become important for measuring scientific validity and quality of all kinds of publications deposited in the most important on-line scientific databases, like WoS, Scopus, Medline, PubMed Central, Embase, Hinari, etc., but also in academic platforms ResearchGate and Academia.edu. Scientometrics use the Impact and Echo factor for measuring the quality of publications in WoS journals, Scopus uses the h-Index, and the most common one used in the last 10 years is Google Scholar index. All of them have advantages and disadvantages, and also positive and negative influences in the academic praxis. One of the greatest, and sadly too common, problems which participants in the academic process encountered are plagiarism and predatory publishing. In order to prevent this severest form of academic fraud, authors must give credit to someone whose work has helped him/her by citing references correctly. This presentations of the symposium "SWEP 2021") analyzed the major components of scientometrics, the basic mechanisms of citations in medical publications and plagiarism, as an opposition to the primary goal of scientific enterprise: search for truth.

I. Masic, A. Kurjak, S. Janković, O. Sinanović, D. Donev, B. Djulbegovic, Kenan I. Arnautovic, M. Zildžić et al.

It is very well known that science is world activity and that there is no good and bad work in the field of scientific research. Nowadays scientific productivity of the individuals, learned societies on regional or state level are measurable parameters. In most of the systems it does include the number of original scientifi papers, quality of journals measured by impact factor and scientific citation index (1-4). There are also additional measurable parameters but for the purpose of this meeting we will avoid discussion about them. New field of scientometrics using the help of impartial and ruthless machines (computers) do help very significantly in evaluation of scientific productivity anywhere in the world. Unfortunately, there are many misused conclusions and interpretation on the data offered by computers. It is clear that some vital important changes are urgently needed. Today’s conference should use rare opportunity having together experts in the field to discuss the problems visible now. This author intends to discuss facts and doubts in writing review articles and chapters in the book (5). Some important flexibility in citation, in particular self citation, should be analyzed. An illustrative examples from author’s own experience will be shown and discussed at the meeting.

Purpose – Purpose of this study is to understand how diaspora tourists as a specific tourist segment symbolically extend their holiday in the country of origin upon returning to the country of current living. Methodology – Aim of the research was to disclose underlying meanings of this specific consumption pattern. Data was collected through 24 semi-structured in-depth interviews with diaspora members from Bosnia and Herzegovina. Analysis was inductive, starting with microanalysis, proceeding then with axial coding around the revealed concept. Throughout analysis the comparative method was applied, alongside researcher's diary and memos as analytic tools. Findings – The concept of ‘bridging’ explains how diaspora tourists cross over from one reality to another on a symbolical level, i.e. when travelling back from the country of origin. It also is a symbolical bridging between complex of identities: the past identities and the present identity, which they have constructed in countries of current living. They seem to use two major strategies: storytelling and product stocking. Contribution – This paper reveals a new concept among diaspora tourists, i.e. their approach to extend their visit to the country of their origin on a symbolical level by using symbolically laden products. The research is further contributing by disclosing that diaspora tourists apply two different strategies in order to symbolically extend their home country holiday: the story telling strategy and the stocking strategy. Finally, it also suggests that the stocking strategy has two phases; the first phase being 'symbolic representation filling phase' and the second phase labelled as 'mainstream trend purchase phase'.

F. Kovac, Haris Memisevic, Emira Švraka

Background: The pandemic of COVID-19 has affected all spheres of life, including education. Teachers at all levels were faced with numerous challenges during the pandemic. These challenges had an impact on their mental health. Objective: The goal of the present study was to examine the depression, anxiety, and stress levels in teachers in Bosnia and Herzegovina. Methods: The sample for this study consisted of 559 teachers (471 female teachers and 88 male teachers). We used the Depression, Anxiety, and Stress Scale (DASS 21) to measure teachers’ emotional states of depression, anxiety, and stress. Results: The findings of this study clearly indicate the high levels of depression, anxiety, and stress in teachers. We also identified that levels of support provided by family members and school administration served as protective factors in the time of crisis. Conclusion: Teachers in Bosnia and Herzegovina have a high prevalence of elevated depression, anxiety, and stress levels. The article concludes with some recommendations on how to improve the mental health of teachers.

L. Karnatovskaia, K. Varga, A. Niven, P. Schulte, Midhat Mujić, O. Gajic, B. Bauer, M. Clark et al.

Background Over a third of critical illness survivors suffer from mental health problems following hospitalization. Memories of delusional experiences are a major risk factor. In this project, ICU doulas delivered a unique positive suggestion intervention targeting the vulnerable time period during critical illness when these memories are formed. Methods Adult critically ill patients were recruited for this single-arm, prospective pilot study. These ICU patients received a positive suggestion intervention daily during their ICU stay in parallel with their medical treatment. The intervention was designed to be delivered over a minimum of two sessions. Feasibility was defined as intervention delivery on ≥ 70% of ICU days after patient enrollment. As a secondary analysis, psychometric questionnaires were compared to those of a historic control cohort of patients receiving standard care in the ICU using adjusted linear regression models. Results Of the 97 patients who received the intervention and were alive at the end of their ICU course, 54 were excluded from analyses mostly for having received only one session because of a short ICU length of stay of < 2 days, transitioning to comfort care or not wanting to answer the study questionnaires. Forty-three patients who completed 2 or more sessions of the positive therapeutic suggestion intervention provided by two trained ICU doulas received it for a median of 4 days (IQR 3, 5), with each session lasting for a median of 20 min (IQR 14, 25). The intervention was delivered on 71% of days, meeting our pre-determined feasibility goal. Compared to historical controls ( N  = 299), patients receiving the intervention had higher severity of illness and longer length of stay. When adjusted for baseline differences, patients both with and without mechanical ventilation who received the intervention scored lower on the Hospital Anxiety and Depression Scale (HADS)—Depression subscale. The intervention was also associated with reduced HADS-Anxiety subscale among ventilated patients. Conclusions Positive therapeutic suggestion delivered by ICU doulas is feasible in the ICU setting. A randomized trial is warranted to better delineate the role that positive suggestion and ICU doulas may play in ongoing interprofessional efforts to humanize critical care medicine. The study was registered on clinicaltrials.gov (NCT03736954) on 03/14/2018 prior to the first patient enrollment https://clinicaltrials.gov/ct2/show/NCT03736954?cond=ICU+Doulas+Providing+Psychological+Support&draw=2&rank=1 .

Background: Breast cancer in women is the second most common and accounts for approximately 18% of all malignant tumors in women worldwide. The etiology of breast cancer is not clear enough. Starting from the assumption that the manifestation of breast cancer may have a multifactorial model, this article compares the population-genetic structure of patients (experimental group) with the population-genetic structure of healthy population (control group). Objective: The aim of the study was to examine the possible genetic basis of the Rh factor relationship with selected homozygous-recessive traits of females with breast cancer, and to diagnose the probability (assess the risk) of developing the disease in healthy women by analyzing homozygous-recessive traits (HRT). Methods: This are an anthroposcopic-qualitative study that included two groups of subjects, experimental and control (a total of 80 subjects). An analysis of the percentages within each group was performed using the Chi-square test. The results are presented in tables, and the accepted level of significance is at the level of p <0.05. Results: In the group of Rh+ subjects, the correlation of this type of Rh factor with the breast cancer was proven, given the frequency of the phenotype of homozygous-recessive traits in them. A statistically significant difference was found for 4 traits, and three are also close to the set significance level. In subjects with Rh- factor, a statistically significant difference was found for only one trait (absence of mallets on the phalanges). Conclusion: Although the number of subjects was relatively small, we can conclude that in the experimental group a higher frequency of recessive phenotypes for the examined traits was recorded, which indicates the genetic load of the subjects from this group. Correlation with Rh factor was observed in the case of subjects of the experimental group with Rh+ factor.

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