Abstract The security of using applications in cloud services and on the Internet is an important topic in the field of engineering. In this paper, two laboratory tests for data transmission protection, specifically designed for different security analysis techniques, are presented and explained. During lab tests on public Wi-Fi networks from the MIDM (“Man in the Middle”) attacks, various monitoring techniques were applied, using a special lab test scenario with Kali Linux penetration tools by creating an SSH tunnel on an Android mobile device. These test benches allow easy data capturing, and the captured data is processed using available software programs. Expected outcomes, practical improvement and security performance assessment are presented in detail, and considered in terms of their value in security engineering. The aim of this paper is to detect and overcome some of the weaknesses of the application of security protocols in a Wi-Fi network environment.

Abstract In the process of designing a system, it is necessary to identify potential threats to that system and to include appropriate countermeasures. The process that helps in finding problems in the initial phase of the system design is the threat modeling. Creating a threat model consists of several steps and there are many tools that can help in automating the procedure. This article deals with the threat analysis for an Ambient Assisted Living (AAL) system based on Wireless Sensor Network (WSN), whose main function is to provide information for carers in order to provide the best possible help to the elderly and disabled. We have identified and analysed 99 potential threats to the considered system, where Denial of Service (DoS) resulted in being the most represented class of threats. After conducting the threat assessment, the obtained results showed that the majority of threats are high-risk and justified the use of threat modeling in the design phase, since they can be utilized in further system development stages.

O amendoim é uma cultura agrícola amplamente conhecida no Brasil. O consumo in natura é o principal meio de aproveitamento da produção. Originário da América do Sul é uma das oleaginosas mais cultivadas em todo mundo, em razão da grande variabilidade nas formas de consumo, sabor e adaptabilidade de produção em áreas tropicais e subtropicais. O objetivo do presente trabalho foi avaliar o desempenho das características agronômicas de crescimento e produtividade de cinco acessos de amendoim sob adubação orgânica. O trabalho foi conduzido no câmpus das Auroras da Unilab, entre abril e julho de 2018. Foi utilizado um delineamento estatístico de blocos casualizados (DBC) com cinco tratamentos e seis repetições. Foram analisadas as características agronômicas: Dias de Emergência (DE), Altura das Plântulas (AP), Números de Ramos, Número de Vagens por Planta (NVP), Número de grãos por Planta (NGP), Peso de massa fresca (PMF), Peso de Massa Seca (PMS) e Peso de 100 grãos (P100G). Os dados foram submetidos à análise de variância em delineamentos de blocos casualizados com três repetições. Os quadrados médios foram comparados pelo teste F e as médias pelo teste de Tukey a 5%. Os acessos Unilab 130 e Unilab 138 destacaram-se em peso e produção de vagens sendo bons genótipos de porte rasteiro. Unilab 107 e 124 situaram-se como intermediários aos demais acessos em relação à produção e podem ser considerados para produção desde que atendidas suas exigências de cultivo. Unilab 130 apresenta-se como um bom genótipo a ser utilizado como genitor em programas de melhoramento.

Genetic variants in FOXO3 are associated with longevity. Here, we assessed whether blood DNA methylation at FOXO3 was associated with cancer risk, survival, and mortality. We used data from eight prospective case–control studies of breast (n = 409 cases), colorectal (n = 835), gastric (n = 170), kidney (n = 143), lung (n = 332), prostate (n = 869), and urothelial (n = 428) cancer and B-cell lymphoma (n = 438). Case–control pairs were matched on age, sex, country of birth, and smoking (lung cancer study). Conditional logistic regression was used to assess associations between cancer risk and methylation at 45 CpGs of FOXO3 included on the HumanMethylation450 assay. Mixed-effects Cox models were used to estimate hazard ratios (HR) and 95% confidence intervals (CI) for associations with cancer survival (total n = 2286 deaths). Additionally, using data from 1088 older participants, we assessed associations of FOXO3 methylation with overall and cause-specific mortality (n = 354 deaths). Methylation at a CpG in the first exon region of FOXO3 (6:108882981) was associated with gastric cancer survival (HR = 2.39, 95% CI: 1.60–3.56, p = 1.9 × 10−5). Methylation at three CpGs in TSS1500 and gene body was associated with lung cancer survival (p < 6.1 × 10−5). We found no evidence of associations of FOXO3 methylation with cancer risk and mortality. Our findings may contribute to understanding the implication of FOXO3 in longevity.

An increasing number of studies have revealed that dysregulated lipid homeostasis is associated with the pathological processes that lead to Alzheimer’s disease (AD). If changes in key lipid species could be detected in the periphery, it would advance our understanding of the disease and facilitate biomarker discovery. Global lipidomic profiling of sera/blood however has proved challenging with limited disease or tissue specificity. Small extracellular vesicles (EV) in the central nervous system, can pass the blood‐brain barrier and enter the periphery, carrying a subset of lipids that could reflect lipid homeostasis in brain. This makes EVs uniquely suited for peripheral biomarker exploration.

Background: Non-alcoholic fatty liver disease (NAFLD) is an increasingly common cause of chronic liver disease and is becoming a major public health problem. NAFLD has been recognized as a hepatic manifestation of metabolic syndrome, associated with systemic diseases such as cardiovascular disease (CVD) and chronic kidney disease (CKD). Objective: The aim of this study was to examine the role of serum LFT parameters and renal function parameters as predictors of unmanifested liver disease. Methods: In this study, the presence of possible liver disease detected by biochemical parameters and confirmed by Transient Liver Elastography (TE) in a group of patients with different stages of chronic kidney disease (CKD) was investigated. Patients with various stages of CKD were divided into five subgroups regarding aetiology: nephroangiosclerosis, diabetic nephropathy, glomerulonephritis and pyelonephritis, autoimmune kidney disease, and polycystic and another morphological kidney disease. Liver stiffness was used to quantify liver fibrosis while Controlled attenuation parameter (CAP) was used to quantify liver steatosis. Functional liver tests and biochemical parameters of kidney function were measured in all patients. Results: Statistical analysis used in this study was a decision tree as a predictive model to map observed variables resulting in the conclusion about outcomes. The application of existing laboratory parameters, in combination with other parameters in presence of the defined etiological factors of kidneys diseases, indicate development of hepatic diseases. Higher values of phosphorus and low values of ferritin in patients with autoimmune kidney disease, and polycystic and another morphological kidney disease, expresses steatosis of the hepatic parenchyma. Conclusion: In contrary, low values of phosphorus and higher values of ferritin in patients with nephroangiosclerosis, diabetic nephropathy, glomerulonephritis and pyelonephritis, are in a favour steatosis of the hepatic parenchyma. Serum values of phosphorus and ferritin are valuable predictors of the liver disease in patients with end-stage kidney diseases of different aetiology.

Purpose – The purpose of this paper is to examine the effects that COVID-19 outbreak has had on tourism in Bosnia and Herzegovina (BiH) and specifically in Sarajevo Canton. Methodology – A survey was conducted in two rounds in March and September 2020, and responses were obtained from 126 running businesses from the tourism in Sarajevo Canton about the actual and expected consequences that COVID-19 outbreak has had on their business. The respondents were asked questions about the effects that COVID-19 has had on their business operations during the first six months of COVID-19 outbreak and their expectations for the future. The questions also included issues related to the government interventions and stimulus packages to overcome the effects of COVID-19 to ensure the sustainability of the tourism in Sarajevo Canton. Findings – Our results show that all businesses have faced a significant downturn in their business operations and had to undertake different measures and activities internally to overcome (and survive) the negative effects of the COVID-19 pandemic. The results also show that there is very low level of satisfaction with the government interventions to tourism. Contribution – The findings illustrate and confirm many flaws in tourism system in Sarajevo Canton and BiH where tourism has been developing organically and without proper integration of the private and public industry. Our findings can be used for planning purposes and improvement of the situation during COVID-19 and post-COVID-19 period.

Abstract Large corporate scandals in the US and Europe, from the early 21st century, such as Enron, Parmalat, WorldCom and many others, have seriously shaken public confidence in the auditors’ work. Consequently, many countries have recognized the need for introduce the forensic accounting as a more advanced and reliable form of protection against manipulative financial reporting by companies, and have completed the accounting profession with the forensic accountant title, as an active fighter against various types of frauds in companies.

OBJECTIVE Patients and medical professionals have a common misconception that cardiovascular diseases (CVD) predominantly affect men, which can lead to less prescribing of cardiovascular drugs to women. This study examined whether there were sex differences in the administration of cardiovascular (CV) drugs in patients admitted to the intensive care unit of the Internal Medicine Clinic of Foča University Hospital (ICFUH). MATERIALS AND METHODS The study comprised 332 patients hospitalized at the ICFUH from January 1st to June 30th, 2019. The following data on leading CVD and risks related to CV drug administration were collected: age, hyperlipidemia (HLD), diabetes mellitus (DM), chronic kidney disease (CKD), liver disease (LD), heart failure (HF), hypertension (HTN), myocardial infarction (MI), and stroke (S). The amount of the CV drugs of interest (statins, antiplatelet drugs, calcium channel blockers, ACE inhibitors, beta blockers, diuretics) administered during hospitalization was expressed as the Defined Daily Dose (DDD)/100 bed-days (BD) for patients of both sexes separately. RESULTS During hospitalization in the intensive care unit of ICFUH, female patients were less likely to be treated with statins than male patients (30.1 vs. 57.5 DDD/100 BD, P<0.05). There was no difference between sexes regarding the use of antihypertensive drugs. Women were less likely to be treated by antiplatelet therapy, more precisely by acetylsalicylic acid (30.4 vs. 36.9 DDD/100 BD, P<0.05). CONCLUSION Our study indicates that there were sex differences in CV drug administration in ICFUH. Presuming that drugs used during hospitalization were at least partially a continuation of the previous therapy prescribed by the family doctor, it is possible that such differences exist in primary care.

Stray dogs may be highly exposed to vector-borne pathogens (VBPs), including zoonotic agents, and therefore may pose a high risk of spreading infections to other animals and humans. Among the Anaplasmataceae, Anaplasma phagocytophilum, A. platys and Ehrlichia canis are commonly identified species in dogs in Europe; however, information on the occurrence of these pathogens in canine populations from Bosnia and Herzegovina (B&H) is still lacking. Thus, the aim of this study was to determine the seroprevalence of Anaplasma spp. and Ehrlichia spp. in stray dogs in the Sarajevo region of B&H and to identify A. phagocytophilum, A. platys, E. canis and E. ewingii by molecular techniques. A total of 903 blood samples of stray dogs were screened by SNAP 4Dx Plus Test for the presence of antibodies against A. phagocytophilum/A. platys and E. canis/E. ewingii. Real-time PCR assays were performed for the detection of Anaplasmataceae, A. phagocytophilum, A. platys, E. canis and E. ewingii in seropositive dogs. Antibodies to A. phagocytophilum/A. platys and/or E. canis/E. ewingii were detected in 187 (20.7%) samples. Seroprevalence was highest for A. phagocytophilum/A. platys (184/903, 20.4%). Two dogs had antibodies to E. canis/E. ewingii, while one dog was found to have antibodies to A. phagocytophilum/A. platys and to E. canis/E. ewingii. Forty-eight (25.7%) of the 187 seropositive dogs examined by Real-time PCR were positive for Anaplasmataceae. A. phagocytophilum was detected in 45 (24%) samples, while one sample was positive for A. phagocytophilum and A. platys. Two samples positive for Anaplasmataceae tested negative in the species-specific PCRs. E. canis or E. ewingii could not be detected in any of the Ehrlichia-seropositive dogs. These findings highlight the need for dog health monitoring, improving the health and welfare of stray dog population, and establishment of effective surveillance systems to combat VBDs.

Background: The new coronavirus SARS-CoV-2 caused a pandemic that threatened all aspects of life and health while worsening the socio-economic situation of the entire population. COVID-19 affects all organs and organ systems. The symptoms of the affected organs can last for a long time after the acute infection. About 1/3 of patients develop neuropsychiatric signs in the clinical course of the disease. The most common symptoms are mental fog, headache, cognitive changes, behavior changes, muscle weakness, anosmia and ageusia. These symptoms may develop due to a direct effect of the virus on the neurons or hyper reactive immune response. Objective: The aim of this article is to describe 2 young adults who developed neuropsychiatric symptoms in the course of Long COVID-19 syndrome. Ischemic vasculitis was proved using CT imaging. Case report: We collected data of two younger females who had previously recovered from the acute form of COVID-19 without respiratory complications. They developed in the next 1-2 months a clinical picture of a brain disorder. In both cases, CT and angiography scans of the brain showed signs of ischemic vasculitis. Neurological therapy has led to an improvement of the neuropsychiatric symptoms. Conclusion: Neuropsychiatric disorders in Long Covid syndrome are common and diverse. Two cases of young adults who developed signs of neurological disorder in the post COVID-19 period were presented, and CT scans of the brain showed signs of ischemic vasculitis.