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S. Papović, J. Panić, T. T. Borović, Nikolet A. Cako Baganj, S. Belić, I. Maksimović, Marina Putnik Delić, S. Gadžurić et al.

The increasingly frequent improper disposal of lithium-ion batteries (LIB) is leading to concerns about the environmental consequences. When they are poured out, the flammable solvents from the electrolytes in LIBs are the threatening soil and plant contamination. If these liquids spill or leak from batteries, they could enter the soil through various pathways and contaminate crops such as cucumber and tomato plants, which have extensive root systems that may facilitate the absorption of ILs. After absorption, some electrolyte components could accumulate inside the plants and have toxic effects, potentially harming plant growth and crop fields. This study investigated how spilling electrolytes with varying combinations of ILs, organic solvents, and lithium salts in different concentrations affects the growth and development of tomatoes and cucumbers. Special attention was paid to examining the influence of electrolyte components on aerial parts and/or fruits of these plants and the levels of metabolites involved in antioxidant protection under stressful conditions, such as malonyldialdehyde (MDA). In this work, certain ILs with bis(trifluoromethylsulfonyl)imide, NTf2, anion have a phytotoxic effect, which negatively affects cucumber and tomato growth and development.

T. T. Borović, S. Papović, J. Panić, Nikolet A. Cako Baganj, S. Belić, S. Gadžurić, Milan B. Vraneš

In this study, a detailed physicochemical characterization of taurine in water is performed based on density and viscosity measurements in the temperature range from T=(293.15 – 313.15) K. Solubility of taurine increases with the temperature increasing. Data obtained from the volumetric and viscosimetric measurements indicate that taurine does not self-aggregate in water. Molecular dynamic simulations provided insight into how taurine molecules behave in water.

Background: Cardiovascular diseases (CVD) are the cause of 17 million deaths a year worldwide, of which 25% are sudden cardiac deaths (SCD). In Europe cardiovascular diseases (CVD) remains a leading cause of death in Europe accounting for 3.9 million deaths each year. Even with well-known risk factors and the current standards of health care, improvement of health and quality of life of CVD patients are still remains one of the biggest public health challenges we must overcome. Objective: The aim of this study was to analize of current strategic documents and relevant facts of WHO and other appropriate institutions regarding CVDs prevention and control for potentialy use in Bosnia and Herzegovina (B&H). Methods: Authors made a narrative review to provide a brief overview of the recent and relevant documents of good practice in prevention, diagnostic and therapeutic approaches of cardiovascular diseases that should be consider as milestones for the health authorities in the Federation of B&H. Results and Discussion: Bosnia and Herzegovina is among the countries with a high risk of CVD together with Albania, Croatia, Czech Republic, Estonia, Hungary, Kazakhstan, Poland, Slovakia, and Turkey. The main public health challenge in Bosnia and Herzegovina is reducing noncommunicable diseases (NCDs): heart disease, stroke, cancer, diabetes and chronic respiratory disease. NCDs are estimated to account for 80% of the country’s annual deaths, and addressing them is the foremost public health priority in the country. Cardiovascular diseases still represent a worldwide public health problem, with some new dimensions caused by challenges caused through pandemic of COVID-19. The well-known cardiovascular risk factors require new and more efficient public health approaches to the prevention and control. Conclusion: Due to the recently developed cardiovascular guidelines that were made by the European Society of Cardiology and World Heart Federation, key priority for health authorities should be is to update the existing CVD guidelines in the Federation of BiH in accordance with the international good practice to support healthcare professionals in their efforts to reduce the burden of cardiovascular disease in both individual patients, as well as at a population level..

H. Djug, Šefik Hasukić, S. Jagodić, Davor Ivanić

Background: The treatment strategy for non-muscle invasive bladder cancer (NMIBC) has not changed significantly over the past 30 years. Chemotherapeutic agents (mitomycin-C, epirubicin, etc.) and BCG (Bacillus Calmette-Guerin) immunotherapy are used as adjuvant intravesical therapy. Objective: To compare the difference between adjuvant chemotherapy and adjuvant immunotherapy in their efficacy of reducing the number of tumor recurrences. Methods: In this prospective clinical study, which included 99 patients with NMIBC from March 2018.–March 2023., we publish the results for all risk groups of patients treated with intravesical chemotherapy Epirubicin or with BCG immunotherapy, after TURBT (Trans urethral resection of bladder tumor) within 1 year. Patients were stratified into 2 groups. The first group was treated with Epirubicin (1 dose within 24 hours of surgery, then 6 weekly instillations and 3 maintenance doses), and the second group was treated with BCG (2-3 weeks after TURBT 6 weekly instillations, and 3 maintenance doses). The monitoring period was 24 months. Results: In patients treated with intravesical chemotherapy, recurrence occurred in 9 patients (17.64%), and in patients treated with BCG, recurrence occurred in 7 patients (14.58%). A similar incidence of disease recurrence was observed in both groups (p=0.787). Conclusion: The results of our study show a similar therapeutic response by risk groups of patients treated with chemotherapy and immunotherapy. Since BCG production will cease in the future, the task of urologists is to introduce intravesical chemotherapy into wider use and to modernize it as a safe and effective method of adjuvant treatment for non-muscle-invasive bladder cancer.

Mediha Skrijelj, M. Muftić

Background: Discus hernia represents an intervertebral disk prolapse. The intervertebral disk provides stability in rest state and distributes the load of the spinal column on the move. Changes that lead to the occurrence of disc prolapse are desiccation, reduction of proteoglycan content, mucoid degeneration, and fibrosing tissue uptake. Predisposing factors of lumbar pain are heavy physical tasks with lifting loads over twenty pounds, especially professional use of heavy tools. Objective: The aims of this article is the review of diagnostics and physical therapy of lumbar disc herniation at levels L4/L5 and L5/S1. Methods: Authors used descriptive method for review lumbar disc herniation including diagnostic procedures and physical therapx based on scientific literature stored in medical databses PubMed, Scopus, Hinari, etc.. Results: The most common area of the spine to experience a herniated disk is the low back, just below the waist level. Herniated disks also commonly occur in the neck.. Conclusion: Rehabilitation is a delicate problem and requires long-term treatment and multidisciplinary cooperation, and is carried out in accordance with the principles of diagnostic and physical therapy of lumbar dics herniation depending of level of demaged and level of causes of lumbar disc herniation. The majority of herniated disks do not require surgery, and respond best to physical therapy. Physical therapists design personalized treatment programs to help people with herniated disks regain normal movement, reduce pain, and get back to their regular activities.

Damira Djukec, Igor Klopotan, Luka Burilović, L. Bobrov, A. M. Cister, João José, L. Marques, H. Ribeiro et al.

S. Pilipović, Ljubomir V. Milanović

: The Jonah sarcophagus from Singidunum belongs to a group of Budakalász travertine sarcophagi. These types of sarcophagi were produced in Budakalász quar-ry(ies) and in Aquincum workshops and then exported via the Danube, before being finished in local workshops. This paper uses the Jonah sarcophagus as a case study to examine the integration of traditional tombstones into Early Christian cultural and social contexts.

The state of the Vatican City and its state-legal system is an interesting and inexhaustible topic for both lawyers and historians, theologians, sociologists, political scientists and other experts who study social phenomena. For a lawyer, the specific legal position of the Vatican and the Holy See, for example in international law and their relationship with other sovereign entities, states and international organizations and other (non-state) entities, is definitely a particularly interesting question. A lot has been written about it. That is why we cannot give the impression that the internal state and legal system of the Vatican has been neglected. For this reason, the author of this paper decided to present one branch of the internal law of the Vatican City State. Criminal law definitely represents an important segment in the legal system of every country. It developed and evolved. The development of criminal law (in the theoretical and practical sense) was accompanied by changes in the penal/criminal legislation. The penal/criminal legislation of this papal "mini-state" is apparently specific. However, the paper before you will not be a discussion about the origin and nature of Vatican penal/criminal law. That will be left for another time. With the Lateran Pact and the creation of the Vatican City-State, positive Italian legislation was taken over. That legislation underwent certain changes by "Vatican law". The latest novelties in the penal/criminal legislation of the Vatican City State are the subject of this work, and the author will try to present them in a concise way and thus try to give his modest development of jurisprudential thought about Vatican (penal/criminal) law.

Marko Aćić, Miloš Grujić

This paper primarily analyzes the classification of international organizations according to different criteria to see the specificity of the EU as a sui generis international organization. The authors specifically examine the legal order of the EU and the process of achieving full membership. They are interested in the EU accession process, particularly for countries in the Western Balkans like Bosnia and Herzegovina, which is covered by the Stabilization and Association Agreement. Candidate countries have access to various EU funds, which the authors analyze as pre-accession assistance. The study assesses Bosnia and Herzegovina’s status in European integration and delves into the use of IPA funds in the country, including its withdrawal, scope, and limitations. The authors emphasize the importance of IPA funds for Bosnia and Herzegovina.

Zijad Nisic, Imana Sokolović, Admir Alagić, Farid Nisić, Nadia Tiganj, S. Sokolović

Right ventricular myxoma are primary rare benign cardiac tumors with each new case contributing to the new evidence in a management and treatment of the disease. We present an 80 year-old male patient with symptoms of fatigue on exertion and previous history of essential hypertension. Right ventricular myxoma was diagnosed on echocardiography and it was confirmed by futher diagnostic procedures. The most serious complication is arrhythmia and sudden cardiac death. A patient was referred for the urgent cardiosurgical intervention and successful extirpation of tumor was performed.

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