OBJECTIVE Despite an increased interest in research of theory of mind (ToM) in recent years - both related to psychopathology (depression and anxiety spectrum disorders) and within the typical adults, the existing literature is scarce and presents some conflicting results. Present study aimed to explore sex differences in ToM, alongside its associations with current anxiety and depression symptoms, in a large sample of typical adults collected online. METHOD Participants completed the 15-minutes survey obtaining socio-demographic data, current self-reported depression and anxiety symptom severity, and ToM ability (the Reading the Mind in the Eyes Task). The sample comprised 605 participants -mostly younger adults, women, and high school graduate/student population. RESULTS The majority of participants reported minimal/mild depressive and anxiety symptoms that were significantly more severe in women. Women also displayed significantly better overall ToM ability than men. Significant negative correlation between the severity of current depressive and anxiety symptoms and ToM ability was also observed, but only in individuals expressing the symptoms requiring clinical attention (such association was absent in those exhibiting minimal/mild symptoms). CONCLUSIONS Present research adds to the existing knowledge on the association between ToM ability, anxiety, and depressive symptoms in typical adults as well as on the sex-differences in this important social cognitive domain. Exploring the factors representing indicators of vulnerability for depression-anxiety spectrum disorders is important for their timely detection and treatment.

Background: In vivo diffuse reflectance spectroscopy provides additional contrast in discriminating nerves embedded in adipose tissue during surgery. However, large datasets are required to achieve clinically acceptable classification levels. This study assesses the spectral similarity between ex vivo porcine and in vivo human spectral data of nerve and adipose tissue, as porcine tissue could contribute to generate large datasets. Methods: Porcine diffuse reflectance spectra were measured at 124 nerve and 151 adipose locations. A previously recorded dataset of 32 in vivo human nerve and 23 adipose tissue locations was used for comparison. In total, 36 features were extracted from the raw porcine to generate binary logistic regression models for all combinations of two, three, four and five features. Feature selection was performed by assessing similar means between normalized features of nerve and of adipose tissue (Kruskal–Wallis test, p < 0.05) and for models performing best on the porcine cross validation set. The human test set was used to assess classification performance. Results: The binary logistic regression models with selected features showed an accuracy of 60% on the test set. Conclusions: Spectral similarity between ex vivo porcine and in vivo human adipose and nerve tissue was present, but further research is required.

The selection and prioritization of suitable strategies to address the challenges to the successful operation and implementation of the bus rapid transit (BRT) system is a common problem faced by practitioners and decision-makers. Recent research has widely discussed the issue, but such assessments have remained limited in the city of Dar es Salaam, Tanzania context, where there are mobility difficulties. The present study addresses this research gap and identifies the most critical challenges to BRT implementation and operation, and recommends the most appropriate strategy for overcoming them. Seven strategies are defined. To prioritize these strategies, five criteria are determined. An integrated multi-criteria decision-making model is introduced. Improved Fuzzy Step-Wise Weight Assessment Ratio Analysis based on the Bonferroni operator was used to determine the importance of the criteria. Measurement of alternatives and ranking according to compromise solution was applied to assess and rank the strategies. The results indicate that “frequent flooding at the Jangwani bridge bus terminal” and “long waiting time at bus stops” are the most critical challenges while the fourth alternative “strengthening the operation and management” is the appropriate strategy to be implemented for successful operation and implementation of the BRT system. After that, a five-phase sensitivity analysis is performed to observe the robustness of the proposed approach. The results indicate the flexibility and applicability of the proposed approach can address real-life problems. The proposed methodology in this work can be instrumental in assisting mass transit operators with the successful implementation and operation of the BRT system.

The aim of this research was to examine characteristics and predictors of auto stimulatory behavior in children with autism spectrum disorders (ASD), as well as to determine the presence of auto stimulatory behavior exhibited by children with ASD. The sample included 43 participants diagnosed with ASD. The instrument used was Behavior Problems Inventory (BPI-01, Rojahn et al., 2002), subscale for stereotyped behavior. Our results show that children with ASD from our sample have lower rates of auto stimulatory behavior, with the most common ones being repetitive body movements, arm shaking, bouncing around, running and pacing. The school type has not proven to be a predictor of auto stimulatory behaviors. However, male participants and those with low functioning ASD exhibit more auto stimulatory behaviors than females and those with high functioning ASD. The presence of auto stimulatory behaviors persists through age. Auto-stimulatory behaviors exhibited by children with ASD can be reduced or eliminated, however it is important to use evidence-based interventions with proven benefits for the child. Since stereotypy is usually automatically maintained and therefore is one of the behaviors that is often difficult to reduce, it is recommended that parents are taught on how to implement interventions in their home environment.

Ćupter is Herzegovinian candy made of must and flour/semolina. Much research about the incorporation of brewers’ spent grains into the human diet has been published. The purpose of this study was to partially replace semolina (Samples 1 and 2) and flour (Samples 3 and 4) with brewers’ spent grains originating from industrial (Samples 1 and 4) and craft breweries (Samples 2 and 3) and study nutritive, chemical, and preference properties of the product. In this research, the authors aimed to find application of this already proven functional ingredient in ćupter production. Values for pH were higher for all samples compared to the traditional recipe. Samples produced with flour had higher values of water activity (0.86 ± 0.01) and moisture (41.82 ± 1.68 and 41.11 ± 1.41). Ash content increased with BSG addition, but between samples, there were no significant differences. Collected data showed significant differences in fat levels. Higher protein content was measured for Samples 4 (6.60 ± 0.17) and 1 (6.13 ± 0.07). The highest total sugar content was measured for Sample 1. The general appearance for all samples was “moderately like”. Nutritive value was improved with the addition of BSG, but recipes and drying should be modified to improve consumer acceptance.

A search for flavor-changing neutral-current couplings between a top quark, an up or charm quark and a $Z$ boson is presented, using proton-proton collision data at $\sqrt{s} = 13$ TeV collected by the ATLAS detector at the Large Hadron Collider. The analyzed dataset corresponds to an integrated luminosity of 139 fb$^{-1}$. The search targets both single-top-quark events produced as $gq\rightarrow tZ$ (with $q = u, c$) and top-quark-pair events, with one top quark decaying through the $t \rightarrow Zq$ channel. The analysis considers events with three leptons (electrons or muons), a $b$-tagged jet, possible additional jets, and missing transverse momentum. The data are found to be consistent with the background-only hypothesis and 95% confidence-level limits on the $t \rightarrow Zq$ branching ratios are set, assuming only tensor operators of the Standard Model effective field theory framework contribute to the $tZq$ vertices. These are $6.2 \times 10^{-5}$ ($13\times 10^{-5}$) for $t\rightarrow Zu$ ($t\rightarrow Zc$) for a left-handed $tZq$ coupling, and $6.6 \times 10^{-5}$ ($12\times 10^{-5}$) in the case of a right-handed coupling. These results are interpreted as 95% CL upper limits on the strength of corresponding couplings, yielding limits for $|C_{uW}^{(13)*}|$ and $|C_{uB}^{(13)*}|$ ($|C_{uW}^{(31)}|$ and $|C_{uB}^{(31)}|$) of 0.15 (0.16), and limits for $|C_{uW}^{(23)*}|$ and $|C_{uB}^{(23)*}|$ ($|C_{uW}^{(32)}|$ and $|C_{uB}^{(32)}|$) of 0.22 (0.21), assuming a new-physics energy scale $\Lambda_\text{NP}$ of 1 TeV.

Modern video streaming services require quality assurance of the presented audiovisual material. Quality assurance mechanisms allow streaming platforms to provide quality levels that are considered sufficient to yield user satisfaction, with the least possible amount of data transferred. A variety of measures and approaches have been developed to control video quality, e.g., by adapting it to network conditions. These include objective matrices of the quality and thresholds identified by means of subjective perceptual judgments. The former group of matrices has recently gained the attention of (multi)media researchers. They call this area of study ``Quality of Experience'' (QoE). In this paper, we present a review of QoE's theoretical models together with a discussion of their properties and implications for the field. We argue that most of them represent the bottom-up approach to modeling. Such models focus on describing as many variables as possible, but with a limited ability to investigate the causal relationship between them; therefore, the applicability of the findings in practice is limited. To advance the field, we therefore propose a structural, top-down model of video QoE that describes causal relationships among variables. We hope that our framework will facilitate designing comparable experiments in the domain.

A farmacologia estuda, além dos fármacos, suas reações químicas e os processos biológicos a que são submetidos no corpo, sendo essencial na formação do médico. Subdivide-se em farmacocinética e farmacodinâmica. Com os anos, tem-se tornado cada vez mais frequente o uso de aplicativos e materiais de consulta rápida no exercício da medicina, bem como o “m-learming”, que visa a facilitar o acesso a conteúdo e atualizações de maneira móvel, conforme a necessidade do usuário. Pensando nisso, a formulação do e- book “Farmacologia: farmacodinâmica e Farmacocinética” tem como objetivo ofertar, de maneira resumida e com facilidade, informações para os estudos sobre introdução à farmacologia este trabalho consiste na produção e validação de um e-book direcionado aos alunos das áreas da saúde, com foco nos estudantes de medicina, e com a finalidade de contribuir com sua formação acadêmica no que diz respeito às bases da farmacologia. É um estudo transversal, realizado a partir de análise quantitativa. Os juízes responsáveis pela validação do e-book foram profissionais das áreas da medicina e da farmacologia. O formulário para validação continha 14 afirmações, as quais deveriam ser classificadas por grau de concordância. A análise dos dados foi feita em caráter quantitativo, por meio do chamado Índice de Verificação de Conteúdo (IVC). Inicialmente, calculou-se o IVC de cada item (I-IVC) e, posteriormente, realizou-se a média desses valores, para encontrar o IVC geral (S-IVC). Obteve-se um bom nível de aprovação nos domínios “objetivo”, "estrutura/apresentação" e "relevância", com níveis superiores a 80% em cada um dos requisitos. O IVC para os itens relacionados a objetivos foi de 88,89%. O requisito “estrutura e apresentação” obteve IVC de 87,04%. E a seção “relevância” alcançou IVC de 91,67%, evidenciando o grau de significância do material julgado.  Quanto ao IVC global neste estudo, alcançou-se o valor de 89,2%, classificando-o como adequado, após apresentar índice de concordância entre os juízes maior ou igual a 0,78. O e-book apresentado, considerado então instrumento válido para circulação em ambiente acadêmico, será colocado à disposição em plataformas digitais, para facilitar o acesso aos profissionais de saúde, discentes e docentes que tiverem interesse no assunto.

BACKGROUND AND PURPOSE: Fully automatic quantification methods of spinal cord compartments are needed to study pathologic changes of the spinal cord GM and WM in MS in vivo. We propose a novel method for automatic spinal cord compartment segmentation (SCORE) in patients with MS. MATERIALS AND METHODS: The cervical spinal cords of 24 patients with MS and 24 sex- and age-matched healthy controls were scanned on a 3T MR imaging system, including an averaged magnetization inversion recovery acquisition sequence. Three experienced raters manually segmented the spinal cord GM and WM, anterior and posterior horns, gray commissure, and MS lesions. Subsequently, manual segmentations were used to train neural segmentation networks of spinal cord compartments with multidimensional gated recurrent units in a 3-fold cross-validation fashion. Total intracranial volumes were quantified using FreeSurfer. RESULTS: The intra- and intersession reproducibility of SCORE was high in all spinal cord compartments (eg, mean relative SD of GM and WM: ≤ 3.50% and ≤1.47%, respectively) and was better than manual segmentations (all P < .001). The accuracy of SCORE compared with manual segmentations was excellent, both in healthy controls and in patients with MS (Dice similarity coefficients of GM and WM: ≥ 0.84 and ≥0.92, respectively). Patients with MS had lower total WM areas (P < .05), and total anterior horn areas (P < .01 respectively), as measured with SCORE. CONCLUSIONS: We demonstrate a novel, reliable quantification method for spinal cord tissue segmentation in healthy controls and patients with MS and other neurologic disorders affecting the spinal cord. Patients with MS have reduced areas in specific spinal cord tissue compartments, which may be used as MS biomarkers.

ABSTRACT This study is the first to examine recent migration from Bosnia and Herzegovina to China in the 21st century. It gives an overview of new Chinese geopolitical and economic circumstances, a historical analysis of migration flows between China and the rest of the world from the 19th to the 21st century, and a survey of recent emigration flows from Bosnia and Herzegovina. The second part presents the results of an empirical study of labour migration from Bosnia and Herzegovina to China and the experiences of 25 migrants, which was conducted using structured interviews The research results show that most in the group plan to stay in China permanently. Some would like to move to North America or Australia. It is characteristic that there are no gender gaps in terms of qualifications or career ambitions. The measures to combat COVID-19 implemented by the Chinese government affected the respondents in different ways.

Background Hospitals are institutions whose primary task is to treat patients. Family-centered care, which considers loved ones as equal partners in patient care, has been gaining recognition in the adult care setting. Our aim was to record experiences of and opinions on communication between hospital-based healthcare providers and patients' loved ones, related but not limited to the rigorous mitigation measures implemented during the COVID-19 pandemic. Methods The Twitter profile @HospitalsTalkTo and hashtag #HospitalsTalkToLovedOnes were created to interact with the Twitter public between 7 June 2021 and 7 February 2022. Conversations surrounding #HospitalsTalkToLovedOnes were extracted and subjected to natural language processing analysis using term frequency and Markov chain analysis. Qualitative thematic analysis was performed on the 10% most interacted tweets and of tweets mentioning “COVID” from a personal experience-based subset. Results We collected 4412 unique tweets made or interacted by 7040 Twitter users from 142 different countries. The most frequent words were patient, hospital, care, family, loved and communication. Thematic analysis revealed the importance of communication between patients, patients' loved ones and hospitals; showed that patients and their loved ones need support during a patient's hospital journey; and that pediatric care should be the gold standard for adult care. Visitation restrictions due to COVID-19 are just one barrier to communication, others are a lack of phone signal, no space or time for asking questions, and a complex medical system. We formulate 3 recommendations to improve the inclusion of loved ones into the patient's hospital stay. Conclusions “Loved ones are not ‘visitors' in a patient's life”. Irrespective of COVID-19, patient's loved ones need to be included during the patient's hospital journey. Transparent communication and patient empowerment increase patient safety and improve the hospital experience for both the patients and their loved ones. Our findings underline the need for the concept of family-centered care to finally be implemented in adult nursing clinical practice.

Background Several hypotheses have been proposed to explain parasite infection in parental species and their hybrids. Hybrid heterosis is generally applied to explain the advantage for F1 generations of hybrids exhibiting a lower level of parasite infection when compared to parental species. Post-F1 generations often suffer from genetic incompatibilities potentially reflected in the higher level of parasite infection when compared to parental species. However, the presence of specific parasites in an associated host is also limited by close coevolutionary genetic host-parasite associations. This study focused on monogenean parasites closely associated with two leuciscid fish species—common bream and roach—with the aim of comparing the level of monogenean infection between parental species and hybrids representing two F1 generations with different mtDNA and two backcross generations with different cyto-nuclear compositions. Results Monogenean infection in F1 generations of hybrids was lower when compared to parental species, in line with the hybrid heterosis hypothesis. Monogenean infection in backcross generations exhibited similarities with the parental species whose genes contributed more to the backcross genotype. The distribution of monogeneans associated with one or the other parental species showed the same asymmetry with a higher proportion of roach-associated monogeneans in both F1 generations and backcross generation with roach in the paternal position. A higher proportion of common bream-associated monogeneans was found in backcross generation with common bream in the paternal position. Conclusions Our study indicated that cyto-nuclear incompatibilities in hybrids do not induce higher monogenean infection in backcross generations when compared to parental species. However, as backcross hybrids with a higher proportion of the genes of one parental taxon also exhibited high level of this parental taxon-associated parasites, host-parasite coevolutionary interactions seem to play an obvious role in determining the level of infection of host-specific monogeneans in hybrids.

Energoinvest, a state-owned enterprise established in Sarajevo in the 1950s, was one of the largest Yugoslav exporters for years (during the 1970s and 1980s), accounting for 5% of the total exports of the Yugoslav economy, or 35% of the total exports of Bosnia and Herzegovina. According to the same source, the company exported complex engineering products, knowledge and technology. It exported complete power plants to many countries around the world, built thermal power plants in India and Indonesia, power plants and facilities in a number of African countries, equipped oil pipelines and power plants in Iraq and the Soviet Union, competing with world-leading companies in related sectors. In addition to offices in many countries worldwide, Energoinvest had formed joint ventures in Mexico, Libya and Pakistan, amongst other countries. Interestingly, Energoinvest, like many other large and high-tech companies in the former Yugoslavia, including the electronics company Ei Nis[AQ1] established in 1948 (once an electronics hub, employing 28,000 workers including thousands of engineers, who developed and produced TV and radio receivers, computers, telephones and household appliances), existed in a communist/socialist state. Indeed, like in other post-communist/post-socialist countries, state-owned enterprises (SOEs) were an integral part of the Yugoslav economic structure, thus providing a greater level of economic independence as measured by the value of economic transactions between countries. Most SOEs vanished due to failed or controversial privatization by a new generation of opportunistic ‘entrepreneurs’. For instance, in 2016 Ei Nis had only one employee, remaining assets and infrastructure having been sold or rented to small firms or entrepreneurs. A long-lasting and promising transition of the ex-Yugoslavian states' economies saved almost none of those global firms. An ultimate aim was to liberalize markets in developing countries by reducing state intervention in the economy. Orthodox Keynesian economics with a high level of social welfare and employment protection has been replaced by a neoliberal policy model that assumed comprehensive structural adjustments. Structural adjustment programmes by individual states centred on a number of key fundamentals: liberalization of domestic markets and trade, monetary policy, labour market deregulation, reduction in the size and scope of the state, fiscal restraint through broadening the taxation base and reducing state spending and social support. In this process, new-breed politicians blindly followed the Washington Consensus principles that were supposed to help developing countries to speed up structural reforms in order to get financial ‘support’ from international financial institutions such as International Monetary Fund (IMF) and World Bank (WB). One

Quantum cryptography can provide a very high level of data security. However, a big challenge of this technique is errors in quantum channels. Therefore, error correction methods must be applied in real implementations. An example is error correction based on artificial neural networks. This paper considers the practical aspects of this recently proposed method and analyzes elements which influence security and efficiency. The synchronization process based on mutual learning processes is analyzed in detail. The results allowed us to determine the impact of various parameters. Additionally, the paper describes the recommended number of iterations for different structures of artificial neural networks and various error rates. All this aims to support users in choosing a suitable configuration of neural networks used to correct errors in a secure and efficient way.