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Bin Zhou, James E Bennett, Aidan P Wickham, Rosie K. Singleton, Anu Mishra, R. Carrillo-Larco, Nayu Ikeda, Lakshya Jain et al.

Joshua P. Kulasingham, H. Innes-Brown, Martin Enqvist, E. Alickovic

Visual Abstract The auditory brainstem response (ABR) is a measure of subcortical activity in response to auditory stimuli. The wave V peak of the ABR depends on the stimulus intensity level, and has been widely used for clinical hearing assessment. Conventional methods estimate the ABR average electroencephalography (EEG) responses to short unnatural stimuli such as clicks. Recent work has moved toward more ecologically relevant continuous speech stimuli using linear deconvolution models called temporal response functions (TRFs). Investigating whether the TRF waveform changes with stimulus intensity is a crucial step toward the use of natural speech stimuli for hearing assessments involving subcortical responses. Here, we develop methods to estimate level-dependent subcortical TRFs using EEG data collected from 21 participants listening to continuous speech presented at 4 different intensity levels. We find that level-dependent changes can be detected in the wave V peak of the subcortical TRF for almost all participants, and are consistent with level-dependent changes in click-ABR wave V. We also investigate the most suitable peripheral auditory model to generate predictors for level-dependent subcortical TRFs and find that simple gammatone filterbanks perform the best. Additionally, around 6 min of data may be sufficient for detecting level-dependent effects and wave V peaks above the noise floor for speech segments with higher intensity. Finally, we show a proof-of-concept that level-dependent subcortical TRFs can be detected even for the inherent intensity fluctuations in natural continuous speech.

Firat Ozcelik, Mehmet Sait Dundar, A. Yildirim, G. Henehan, Oscar Vicente, J. Sánchez-Alcázar, Nuriye Gokce, Duygu T. Yildirim et al.

Jehona Ismaili, P. Ibrahimi, V. Berisha-Muharremi, M. Berbatovci-Ukimeraj, Nora Istrefi, B. Gjikolli, A. Batalli, A. Poniku et al.

J. Panić, Arianna Defeudis, L. Vassallo, Stefano Cirillo, Marco Gatti, Antonio Esposito, Serena dell’Aversana, Salvatore Siena et al.

Alejna Krilić, Aleksandra Nikolić, V. Falan, Đani Đorđević, Merima Makaš, Almir Toroman

Abstract The dairy industry has been undergoing changes for years, introducing innovations and pushing the boundaries of the category and consumer experience. Numerous factors, such as economic, psychological, cultural, socio-demographic, personal and many others, influence the decision to buy and consume a certain dairy product. It is important to qualitatively research and identify factors that significantly influence consumer behavior. Consumers also set certain criteria when it comes to brand, taste, nutritional value, marketing, product origin, on the basis of which we conclude that knowing consumer preferences also means success in the market. Due to the previously stated reasons, the main goal of this paper is to determine consumer purchasing behavior towards dairy products and their preferences.The survey method was used in the research to collect primary data, and a survey questionnaire was used as a research instrument. A total of 250 respondents participated in this research, which is conducted in Bosnia and Herzegovina.

Almedina Moro, A. Softić, Maja Travar, Šejla Goletić, J. Omeragić, Amira Koro-Spahić, N. Kapo, Visnja Mrdjen et al.

The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which led to the COVID-19 pandemic, has significantly impacted global public health. The proper diagnosis of SARS-CoV-2 infection is essential for the effective control and management of the disease. This study investigated the SARS-CoV-2 infection using RT-qPCR tests from laboratories in Bosnia and Herzegovina. We performed a retrospective study of demographic data and Ct values from 170,828 RT-qPCR tests from April 2020 to April 2023, representing 9.3% of total national testing. Samples were collected from 83,413 individuals across different age groups. Of all tests, 33.4% were positive for SARS-CoV-2, with Ct values and positivity rates varying across demographics and epidemic waves. The distribution was skewed towards older age groups, although lower positivity rates were observed in younger age groups. Ct values, indicative of viral load, ranged from 12.5 to 38. Lower Ct values correlated with higher positive case numbers, while higher Ct values signaled outbreak resolution. Additionally, Ct values decreased during epidemic waves but increased with the dominance of certain variants. Ct value-distribution has changed over time, particularly after the introduction of SARS-CoV-2 variants of interest/concern. Established Ct value trends might, therefore, be used as an early indicator and additional tool for informed decisions by public health authorities in SARS-CoV-2 and future prospective pandemics. Moreover, they should not be overlooked in future epidemiological events.

Marijana Kotlaja, Sanja Kutnjak Ivkovich, Jon Maskály, Sandra Kobajica, P. Neyroud

The current study applies the key components of GST to explore the relationship between stress and misconduct during the COVID-19 pandemic. We analyzed the answers provided by a sample of 480 police officers from Bosnia and Herzegovina and discovered that the relationship between strain and willingness to engage in police misconduct during the pandemic is complex; not all types of stressors were related to all forms of police misconduct included in our study. The two strongest organizational stressors were perceptions that the police agency was ineffective in dealing with the pandemic and that there was a lack of personal protective equipment for police officers. Fear for their own personal health, fear of COVID-19, and concerns that COVID-19 is much more dangerous than the flu were significant personal stressors related to their willingness to engage in police misconduct. Police's own willingness not to wear a mask and to visit friends and family with whom they do not live decreased the perception that the community is not adhering to the COVID-19 rules and regulations. Living with a partner was also negatively associated with the respondents’ willingness to engage in misconduct.

Amira Jagodić Ejubović, Malik Ejubović, Rijad Jahić, Amer Brkovic, Emina Letic, M. Vujnić, O. Lepara, Avdo Kurtović et al.

Background Acute pancreatitis (AP) is a condition with various etiological factors, marked by the sudden onset of inflammation in the pancreatic tissue. Predicting the severity and potential mortality of AP involves analyzing clinical data alongside laboratory tests and imaging. Among several grading methods with strong predictive capabilities for illness severity and mortality, the Bedside Index for Severity in Acute Pancreatitis (BISAP) score is notable. This study aims to explore the potential role of laboratory markers, specifically red cell distribution width (RDW), RDW/platelet (PLT) ratio, and mean platelet volume (MPV), in predicting disease severity, with patients being stratified according to the BISAP scoring system. Materials and methods This research included 161 patients hospitalized at Cantonal Hospital Zenica in Zenica, Bosnia and Herzegovina, with a diagnosis of AP. The BISAP score was determined based on laboratory and radiological analyses. This score was used to evaluate potential correlations between laboratory findings such as RDW, RDW/PLT ratio, and MPV. Results The age range was significantly higher in patients with BISAP scores ≥3 (68 years, 64-76) compared to those with BISAP scores <3 (59.5 years, 42.75-69) (p = 0.000). RDW values were also significantly higher in patients with BISAP scores ≥3 (15.6%, 14-16.9) compared to those with BISAP scores <3 (13.5%, 13-14.1) (p = 0.000). Hospital stay duration was significantly longer for patients with BISAP scores ≥3 (9 days, 6-11) compared to those with BISAP scores <3 (5 days, 5-7) (p = 0.000). Additionally, the RDW/PLT ratio was significantly lower in patients with BISAP scores <3 (0.063 ± 0.02) compared to those with BISAP scores ≥3 (0.09 ± 0.059) (p = 0.012). Conclusion Our results indicate a significant difference in RDW/PLT ratios between patient severity groups based on BISAP scores (scores <3 vs. ≥3). This suggests that the RDW/PLT ratio may serve as a useful predictor for assessing the severity of AP. However, further research is needed to explore the full potential of the RDW/PLT ratio in evaluating AP patients.

Elvis Hozdić, R. Hasanagić

This study investigates the impact of infill density on the mechanical properties of fused deposition modeling (FDM) 3D-printed polylactic acid (PLA) and PLA reinforced with carbon fiber (PLA+CF) specimens, which hold industrial significance due to their applications in industries where mechanical robustness and durability are critical. Exposure to cooling lubricants is particularly relevant for environments where these materials are frequently subjected to cooling fluids, such as manufacturing plants and machine shops. This research aims to explore insights into the mechanical robustness and durability of these materials under realistic operating conditions, including prolonged exposure to cooling lubricants. Tensile tests were performed on PLA and PLA+CF specimens printed with varying infill densities (40%, 60%, 80%, and 100%). The specimens underwent tensile testing before and after exposure to cooling lubricants for 7 and 30 days, respectively. Mechanical properties such as tensile strength, maximum force, strain, and Young’s modulus were measured to evaluate the effects of infill density and lubricant exposure. Higher infill densities significantly increased tensile strength and maximum force for both PLA and PLA+CF specimens. PLA specimens showed an increase in tensile strength from 22.49 MPa at 40% infill density to 45.00 MPa at 100% infill density, representing a 100.09% enhancement. PLA+CF specimens exhibited an increase from 23.09 MPa to 42.54 MPa, marking an 84.27% improvement. After 30 days of lubricant exposure, the tensile strength of PLA specimens decreased by 15.56%, while PLA+CF specimens experienced an 18.60% reduction. Strain values exhibited minor fluctuations, indicating stable elasticity, and Young’s modulus improved significantly with higher infill densities, suggesting enhanced material stiffness. Increasing the infill density of FDM 3D-printed PLA and PLA+CF specimens significantly enhance their mechanical properties, even under prolonged exposure to cooling lubricants. These findings have significant implications for industrial applications, indicating that optimizing infill density can enhance the durability and performance of 3D-printed components. This study offers a robust foundation for further research and practical applications, highlighting the critical role of infill density in enhancing structural integrity and load-bearing capacity.

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