The distribution of services across heterogeneous edge and cloud infrastructures in Beyond 5G (B5G) and Sixth-Generation (6G) networks increases operational complexity, while existing MANagement and Orchestration (MANO) solutions remain single-domain and lack unified telemetry or autonomous cross-domain decision mechanisms. Prior work proposes cross-domain orchestration concepts, but most validations rely on simulation and overlook interoperability issues, non-stationary latency, and inconsistent Key Performance Indicator (KPI) models in real Network Function Virtualization Infrastructure (NFVI) deployments. This paper introduces a modular, technology-agnostic Zero-touch Network and Service Management (ZSM) framework that provides unified NFVI abstraction and a multi-criteria decision engine that jointly considers latency, compute load, and energy consumption for autonomous service placement, scaling, and dynamic resource provisioning. Evaluation in a real-world deployment across geographically distributed testbeds demonstrates that our ZSM framework mitigates latency spikes by up to 96%, reduces overloaded-node latency by 36%, and maintains stable performance under variable load. These results confirm the practicality and effectiveness of zero-touch, multi-domain orchestration for future 6G compute-continuum environments.

Razvijanje talenata predstavlja jednu od ključnih aktivnosti u okviru talent menadžmenta i značajno doprinosi zadovoljstvu zaposlenika i ukupnoj organizacijskoj uspješnosti. Cilj ovog istraživanja bio je ispitati nivo razvijenosti aktivnosti razvoja talenata u uslužnim poduzećima u Bosni i Hercegovini, kao i analizirati njihov utjecaj na zadovoljstvo zaposlenih. Istraživanje je provedeno na uzorku od 101 poduzeća, korištenjem Likertove skale i upitnika za menadžere i talentirane zaposlenike. Pouzdanost skala potvrđena je visokim vrijednostima Cronbach-α koeficijenata (α = 0.78 za razvoj, α = 0.84 za zadovoljstvo). Dobiveni rezultati pokazuju da su razvojne aktivnosti u prosjeku visoko razvijene, posebno u malim i srednjim poduzećima. Regresijska analiza je potvrdila da razvojne aktivnosti značajno pozitivno utječu na zadovoljstvo zaposlenih (β = 0.355, p < 0.001), što ukazuje da ulaganje u razvoj talenata nije samo organizacijska obaveza, već i ključna strategija za povećanje zadovoljstva i lojalnosti zaposlenika. Ovi nalazi pružaju važne smjernice za unaprjeđenje HR praksi u organizacijama koje žele zadržati i motivirati svoje talente. Ključne riječi: Talenti, razvijanje talenata, zadovoljstvo zaposlenih

Introduction: Regular physical activity reduces the risk of cardiovascular diseases (CVD). The aim of this study was to examine the association of physical activity with the severity of carotid disease. Materials and methods: This cross-sectional study involved 506 patients from the Vascular Surgery Clinic at the Institute for Cardiovascular Diseases "Dedinje", who underwent carotid endarterectomy from 2012 - 2017 . The severity of carotid disease was assessed based on the degree of carotid stenosis, plaque type, and patients' symptomatic status before surgery. Patient physical activity data were collected using the standardized Baecke questionnaire. Univariate and multivariate logistic regressions were performed to examine the association between physical activity and the severity of carotid disease. Results: According to univariate analysis, there was no statistically significant association between any form of physical activity (occupational, sports, or recreational) and the degree of carotid stenosis, nor with other characteristics. Also, physical activity was not associated with complicated carotid plaque. The only characteristic associated with complicated carotid plaque was the use of oral anticoagulants in therapy (OR=2.91; 95% CI=1.12-7.52; p=0.028). The relationship between physical activity and symptomatic carotid disease was not observed, but according to multivariate analysis, the following factors were associated with symptomatic status: age (OR=0.97; 95% CI 0.94-0.99; p=0.016), gender (OR=0.64; 95% CI 0.44-0.99; p=0.028), family history of CVD (OR=0.63; 95%CI 0.43-0.94; p=0.022), use of clopidogrel (OR 1.79; 95% CI 1.18-2.71; p=0.006) and ACEIs in therapy (OR=1.60; 95% CI 1.02-2.53; p=0.041). Conclusion: Physical activity was not associated with carotid disease severity.

As part of many national energy transition strategies, solar photovoltaic (PV) capacity is expected to increase significantly because PV deployment represents a key pathway for decarbonizing the energy sector. Alongside utility-scale installations, distributed PV systems connected to near-end users are becoming increasingly common in distribution networks. However, integrating intermittent sources without demand-matching capabilities introduces challenges related to operational network constraints. Consequently, distribution system operators (DSOs) limit PV integration to an acceptable level, referred to as hosting capacity (HC). Moreover, with increasing PV penetration, the curtailment of production becomes necessary during certain periods. Although curtailment has traditionally been avoided owing to the associated loss of clean energy, techno-economic studies show that shifting toward curtailment management can increase both HC and profitability. Curtailment management can be achieved through flexible PV power control, energy-storage integration, demand-side management, and flexible network regulation devices. This study specifically focuses on the techno-economic performance of flexible PV power control and compares it with the conventional approach without curtailment management, energy storage-based solutions, and their combination. The analysis was conducted on a modified IEEE 33-node test network, and key network constraints were incorporated. Using sequential Monte Carlo simulations with correlated stochastic time-series data for PV production, load profiles, and electricity prices over the years, the optimal PV and/or energy storage capacities were determined for various configurations. The results demonstrate that flexible curtailment management can increase both PV HC and expected profit, providing DSOs with boundary HC values while offering investors insight into the profitability of further PV integration.

This year the journal “Medical Archives” celebrates 80th anniversary of the establishiment (1947-2026). With the name “Medicinski Arhiv” this journal was founded in the year 1947 as official journal of the Society of physicians of Bosnia and Herzegovina (B&H). The first Editorial board was consisted of professors of the Faculty of Medicine of the University in Sarajevo opened in November 16th 1947: Vladimir Čavka, Blagoje Kovačević, Bogdan Zimonjić and Ibro Brkić. “Medical Archives” journal was a key milestone that helped in education of all academic and professional staff that became the foundation of Bosnian and Herzegovinian medicine, as a science and health care as a profession. The oldest medical journal in BiH was “Jahrbuch des Bosnisch-Herzegowinischen Landesspitales in Sarajevo” (“Annual of the National Hospital in Sarajevo”) which was established in 1897 and printed in German language in the period from 1897 until 1900. From the year 1950 “Medicinski Arhiv” was included in the most influential and important index database MEDLINE, as one of oldest medical journals in Souut-Eastern Europe. The first aim of journal was to give a opportunity to young researchers from BiH to present their scientific and research work to wider community. The tradition of publishing of “Medical Archives” as the most recognizable journal in BiH, was kept by Editor of Professor Izet Masic in 1993 who in extraordinary and difficult occasions (during wartime in BiH from 1992 until 1995) re-established journal and continued printing of the war issues. Hopefully the MEDLINE did not stop to continue receiving “Medicinski arhiv” journal and did not stop accept of published articles of “Medicinski Arhiv” in Medline/PubMed, SCOPUS, EMBASE, HINARI, EBSCO, and a lot of other indexed databases. From the year 2013 articles published in “Medical Archives” was included in PubMed Central with full papers (in extenso). Today “Medical Archives” belong to the most cited journals in former Yugoslavia countries with h-Index 38 in SCImago rank, it means 38 published papers in “Medical Archives” were cited 38 times in other indexed scientific journals worldwide, with SJR 0.33 and Q3 in the year 2024.

Background: Diverticula of the gastrointestinal tract are common in older adults, most often affecting the colon. While typically asymptomatic, acute diverticulitis represents the most frequent complication and may lead to severe outcomes, including perforation, abscess formation, and diffuse peritonitis. Duodenal diverticula on the other hand is a rare clinical entity, and is frequently detected incidentally during proximal endoscopy. While most cases are asymptomatic, inflammation of periampullary duodenal diverticula may result in serious complications. Acute pancreatitis secondary to duodenal diverticulitis is exceedingly rare and has been described almost exclusively in isolated case reports. Clinical obesity, particularly increased visceral adiposity, has been associated with more severe inflammatory responses in complicated diverticular disease and may influence disease progression and outcomes. Objective: The aim of this article was to present a case of severe acute pancreatitis with peripancreatic fat necrosis caused by acute duodenal diverticulitis in a patient with clinical obesity. Case presentation: A patient presented with diffuse abdominal pain and was diagnosed with severe acute pancreatitis based on laboratory findings and radiological imaging. Comprehensive diagnostic evaluation, including radiological studies, proximal endoscopy, and endoscopic ultrasound (EUS), excluded common etiology. Further assessment identified a markedly enlarged periampullary duodenal diverticulum as the most likely trigger, associated with peripancreatic visceral fat necrosis and with signs of multiorgan dysfunction. Subsequent anthropometric and body composition assessment confirmed clinical obesity with increased visceral fat area, which was considered a contributing factor to disease severity. Targeted pharmacological therapy combined with individualized nutritional intervention resulted in complete clinical remission. Conclusion: Complicated diverticular disease has been shown to be associated with obesity and increased visceral adipose tissue. Periampullary duodenal diverticulitis complicated by peripancreatic fat necrosis in patients with clinical obesity and increased visceral fat area is rarely described in the literature. Appropriate pharmacological treatment combined with a targeted dietary regimen aimed at reducing visceral adiposity may result in complete remission of severe acute pancreatitis. In patients with acute pancreatitis of unknown etiology and concomitant clinical obesity, duodenal diverticulitis and peripancreatic fat necrosis should be considered as potential underlying causes.

Background: Artificial intelligence (AI) is applied in numerous areas of society and has also led to significant changes in the field of medicine. Medicine is a branch of science of exceptional importance, and it is therefore necessary to ensure a high level of patient protection. The quality of healthcare has significantly improved through the use of artificial intelligence in various stages of the medical process, from the analysis of medical data and diagnostics, through therapy planning, to patient monitoring and the management of healthcare systems. Objective: The aim of this paper is to analyze the civil law aspects of artificial intelligence in medicine, with a particular focus on questions of liability for damage resulting from the use of such systems. Methods: The paper will first present the basic characteristics and areas of application of artificial intelligence in medicine, and then examine potential sources of damage and the legal basis for the liability of various stakeholders, including AI system manufacturers, software developers and data providers, healthcare institutions, and healthcare professionals. Special attention will be given to the challenges of proving causation and allocating liability in situations where decisions are made or supported by autonomous algorithmic systems. Results and Discussion: However, at the same time, numerous legal issues arise, particularly in the field of civil liability in cases where the application of artificial intelligence results in harm to a patient. Given the great importance of medicine and the need to ensure a high level of patient protection, the application of artificial intelligence must be accompanied by appropriate legal protection. The paper gives answers to a number of questions, with particular emphasis on the question of who may be held liable for damage caused by the use of artificial intelligence in medicine, as well as under which regulations and in what manner such liability is determined. Conclusion: Artificial intelligence has the potential to significantly enhance medical practice, its application must be accompanied by appropriate legal mechanisms that ensure patient protection and clearly define the responsibility of all participants in the system. Future legal development in this area will likely focus on further adapting existing civil law institutions to the specificities of artificial intelligence, while simultaneously strengthening preventive risk management mechanisms and transparency of AI systems in medicine.