Objective: The aim of the study was to determine the possible impact of the total daily amount of skim milk on the level of bilirubin and liver enzymes through regression analysis. Materials and Methods: The study included 63 Holstein-Friesian cows. They were formed in 3 groups, based on the amount of daily milk production. Peripheral blood was punctured, through which the activities of total bilirubin were analyzed (μmol/L), as well as liver enzymes: alanine aminotransferase – ALT (U/L), aspartate aminotransferase – AST (U/L), lactate dehydrogenase – LDH (U/L) and alkaline phosphatase – ALP (U/L). Results: The lowest concentration of total bilirubin in blood plasma was recorded in the group of cows that have the lowest daily milk production (1.295 ± 0.255 µmol/L), and highest concentration is in cows that produce the most milk (1.855 ± 0.159 µmol/L), but intergroup differences are not significant. Regression analysis found a statistically significant relationship between the amount of produced daily milk and the concentration of total bilirubin (R2=0.132, p=0.0050.05). Conclusion: The activities of bilirubin and liver enzymes in the examined cows were in physiological balance. This indicates that the cows on the farm are raised in modern and good zootechnical and feeding conditions. In such conditions, dairy cows are able to maintain blood composition and homeostatic integrity within physiological limits and adequate reproductive and productive capacity.

Attacks by dogs, primarily stray dogs, are a very common problem faced by both underdeveloped and developed local goverments. The damage caused by attacks from stray dogs has multiple, and often long-lasting, harmful consequences for their victims, which are also reflected on members of their families. This manuscript provides a veterinary-epidemiological definition of the concept of dogs, as well as their legal definition in the context of „dangerous things“, and the psychological aspect that is regularly manifested in victims. Analyzing the legislation of Bosnia and Herzegovina, with a comparative presentation of the regulations of the EU member states, systematic overviews and answers are given, which are important for the improvement of existing regulations and harmonization of law and jurisprudence.

Simple Summary The aim of the study was to determine the morphological and morphometrical features of the auditory ossicles in the red fox. Moreover, for the first time, shape analysis was performed on all the middle ear bones by geometric morphometry. The auditory ossicles play a vital role in transmitting sound waves through the middle ear. The malleus was considered to be the largest bone, with three distinctive processes. The overall shape of the incus was found to be similar to that in other mammals. The presence of a prominent muscular process was noted on the head of the stapes and the convex base which closes the window of the inner ear. Abstract The use of carnivores as experimental models in auditory biology has led to a significant improvement regarding our understanding of the structure and function of the ear. Considering that data regarding the anatomy of the middle ear in the red fox are rare, this study aimed to describe the morphological and morphometrical features of the auditory ossicles in the red fox, as well as to provide their shape characteristics by geometric analysis. Nine adult red foxes were used in the study. The malleus, incus and stapes were extracted from the middle ear, prepared, photographed and measured using the software. For the geometric analysis, 19 landmarks were used. Following Principal Component Analysis (PCA), PC1 was found to explain approximately half of all variance (incus: 49.97%; malleus: 49.93%; stapes: 58.49%). The study demonstrated the similar anatomical organization of the auditory ossicles in line with important morphometric and basic geometric data, which can contribute to this field and add a useful perspective to the literature.

Aim Clips in neurosurgery are made of titanium alloys, which reduce artifacts on computed tomography (CT). The radiological advantage of plastic clips on the CT image was demonstrated when they were placed in an inter-hemispherical position at an angle of 90º. The aim of this study was to investigate the behaviour of the clip placed at different angles. Methods Sixty heads of domestic pigs were divided into two groups, in group 1 a titanium clip was placed to the interhemispheric position at an angle of 90º, 45º, 0º, ten heads for each angle. In group 2 a plastic clip was placed in the same way. CT scan of the brain was performed for each angle. The size of the density and possible artifact were measured on CT. Results The size of the titanium clip ranged from 17.05 mm at an angle of 0º in the axial plane to 91.47 mm at an angle of 0º in the sagittal plane. The average size of the plastic clip ranged from 6.4 mm at an angle of 0º in the axial plane to 23.22 mm in an angle of 90º in the sagittal plane. Artifacts were observed only in the titanium clip. Conclusion Plastic clips have shown radiological advantages over titanium clips in the CT image. The average density size of the plastic clip in all planes and all angles was smaller than the titanium clip.

Introduction. Diabetes mellitus represent a global problem in public health, and the incidence of diabetic foot is constantly increasing Patients with diabetes have a tendency to infections, due to previously present neuropathy, vascular insufficiency, as well as neutrophil dysfunction. The most important risk factor is the existence of peripheral neuropathy, and it is present in 30% to 50% of patients with diabetes. The foot becomes sensitive to trauma as a result of sensory, motor and autonomic dysfunction, and there is excessive pressure in the deformed foot, also the development of ischemia. Case  report. A 59-year-ol male patient sought medical help at the Clinic of Emergency Medicine of the Clinical Center in Sarajevo. He had edematous ulcers on the foot of his right leg. On the first day of therapy, the antibiotic amoxicillin + clavulanic acid, 875/125 mf film-coated tablets were included. Ulcerative formation on the injured finger healed relatively slowly in the first five days of therapy, so from the sixth day of therapy, another broad-spectrum antibiotic per os was included, for synergistic effects: metronidazole 500 mg tablets. On the tenth day of the therapy, visible progress was observed in the healing of the injured finger. Ultimately, the treatment of the injured finger was completed routinely and successfully. Conclusion. Identification of risk factors as well as patients’ education is an important prerequisite for the prevention of complications arising from the chronic course of diabetes. Early initiation of treatment, with an adequate multidisciplinary approach, can cure ulcerative, inflammatory diabetic foot, which in our case corresponded to the Wagner-Meggitt classification, superficial ulcer, with a corresponding gradation 1.

Background: The aim of the study was to find out what happens to erythrocytes and their forms during life and after death as a result of high water temperature.Methods: Heat stress was used on a rat model.to investigate the effects of different temperature intensities (37°C and 44°C) and exposure time (20 min and until the time of death) on erythrocyte morphology. Total of 23 Wistar rats were divided into two groups: 37°C as control group and 44°C as trial groups. The trial groups were classified into antemortem the exposure time of 20 min and postmortem groups exposure time until fatal outcome. The anaesthetised rats were exposed to preheated water using the water bath. May-Grünwald-Giemsa colouring technique was applied on blood samples taken from the abdominal aorta. Results: Exposure of Wistar rats to water temperature in groups KG37 and G44 led to a significant changes in core temperature. In the control group, the thermoregulatory mechanism established normothermia, and in G44 hyperthermia was detected during 20 minutes of exposure. The frequency of heat stroke in group G44 was 43.8%. Target cells and anulocytes were predominant in antemortem group at 44°C, while anulocytes and spherocytes in postmortem groups 44°C, respectively. Dacryocytes with spherocytes were significantly higher in postmortem group 44°C than in antemortem group 44°C (p=0.002, p=0.017, respectively).Conclusions: Poikilocytosis is associated with the exposure length and temperature intensity. Following a fatal outcome dacryocytes with spherocytes at 44°C were significantly more than in corresponding antemortem groups.

Introduction/Objective Cat bites can seriously harm human health, especially if the bite comes from a stray or feral cat who is not under veterinary supervision. Cat bites are the second most common mammal bites, second only to dog bites, and responsible for ¾ of all bites that result in infection. We are presenting the case of a young woman whose hand had been bitten by a stray or feral cat. The objective of this case study is to stress the importance of timely medical treatment and wound management based on guidelines for treating bites inflicted by stray or feral cats, aiming to prevent possible complications. Case report A 32-year-old woman was admitted and examined in the University of Sarajevo Clinical Centre Emergency Department on the third day after being bitten by a stray or feral cat, by which time all signs of inflammation had already developed at the site of the injury-her right hand. Medical help was provided based on guidelines that included specific wound dressings recommended for animal bites, a prescription of antibiotics, analgesics and an anti-tetanus shot. The patient fully recovered with no complications. Conclusion The specific anatomy of the cat's canines enables them to penetrate deeply into the bitten tissue, which can cause an innoculation of a wide range of microorganisms from the cat's mouth into the patient's bloodstream. This can cause serious inflammatory processes, especially in immunocompromised patients. Adequate medical treatment of injuries resulting from cat bites is necessary as soon as possible, but no later than 48 hours after the incident.

Athletes who train in public places in urban and rural areas are just as attacked and injured by dogs of known owners as they are by dogs with no owners, in a relatively equal proportion. The largest number of bites occurs in the summer, what makes up half of all bites, just when sports activity is most pronounced. Athletes who are most often exposed to potential attacks and bites are cyclists, long-distance athletes, marathon runners, recreational athletes, etc. both during training and competitions. Off-road cyclists are at a significantly higher risk of dog attacks because cycling takes place off-road, that is, away from urban areas. Dog attacks can adversely affect the psycho-physical readiness of athletes. In Bosnia and Herzegovina there have been no cases of injuries to athletes recorded by competent medical institutions or umbrella sports associations. It is necessary to work on more efficient administration (registration and recording of attacks and bites of dogs). It is of utmost importance to educate athletes on dog behaviour, the reasons for their aggressive behaviour and causal mechanisms of dog attacks as well as the first aid education, what can have a great impact on reducing further complications.