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Introduction: In dental clinical practice, devices such as mobile phones and DSLR cameras (Digital Single Lens Reflex) are used to take intraoral and extraoral photographs. The existence of a large number of studies would allow the establishment of standards for the analysis of photographs and their wider use in daily practice in order to establish a rapid diagnosis, predictability of results and the development of teledentology during the COVID-19 pandemic. The aim of the pilot study was to determine the repeatability of point positioning in the analysis of facial symmetry in digital 2D photography. Materials and methods: One face was photographed using two different photography techniques. Points were positioned in one photo and used for each subsequent measurement. Two evaluators positioned 20 points in three time-separated periods. Results: The results suggest a relatively high degree of agreement of the point positioning provided by the two evaluators. Absolute matching of estimates was registered on 22 parameters (ICCs = 1.00), while on another 17 this value was high (ICCs >.96) Conclusion: This study shows that the values of the interclass of correlation coefficients calculated by the method of two-way random effects for each of the six indices are higher than the values of the lower limit of acceptability (ICC> 0.70). It is necessary to do additional research that will include a larger sample and different phone models to establish the diagnosis of facial asymmetry and the development of teledentistry.

Guilt of minors is the focus of scientific and professional thematization, which has gained regional relevance through numerous tragic events, i.e. crimes committed by minors. Tragic events, with minors as perpetrators of the most serious crimes, require reconsideration and analysis of both current situation in the field of preventive work, and the current situation the field of prescribed legislative solutions in the field of criminal law. In this paper, the authors referred to the legislative aspects of the guilt of minors, where the focus of the paper is on the concept of guilt in juvenil criminal law and the perception of quilt from aspects of prescribed criminal sanctions for minors and the conditions for their imposition and the age limits of the capacity of minors to bear quilt. Certain aspects of the prescribed incriminating behavior of minors and their causal connection with the quilt of the parents, are also problematized. In this sense, an overview is given of the challenges of searching for appropriate de lege ferenda solutions, as well as dilemmas and shortcomings arising from the dubious nature of certain prescribed provisions that are directly related to the delinquency of minors.

Background: Globally, life expectancy is increasing, leading to an equal proportion of elderly and young individuals, which carries extensive implications. In Bosnia and Herzegovina (BiH), the average age at death in 2021 was 77 years, positioning BiH in the middle of the global list of average life expectancy. Current studiesinvestigate whether the prevalence of psychiatric disorders increases or decreases with age, but results are inconsistent regarding the role of age.There is no prior research on mental disorders in the elderly population in BiH. The experience of the previous war in BiH and the post-war complex “transitional period” have been associated with specific challenges to the mental health of this population, inspiring our research topic. Objective: The aim of this study was to investigate the psychiatric morbidity in hospitalized individuals aged≥55 years. Methods: The sample consisted of all patients over age 55 treated at the Department of Psychiatry in Tuzla between January 2018 and December 2020 (N=637), divided into four age categories. Data were obtained from medical records, and for research purposes, a specific questionnaire was constructed. Results: The predominant psychiatric morbidity stemmed from the category of affective disorders, most common within the “55-64 years” age group, while organic mental disorders were more prevalent in other age groups.Substance use disorders were present in patients aged “55-64 years”, with a sharp decline in their prevalence in older age. Female participants had a significantly higher prevalence of affective, psychotic, neurotic, and stress-related disorders, whereas male participants exhibited an increased prevalence of organic mental and substance use disorders. Conclusion: In total sample, the most prevalent diagnoses belong to the category of affective disorders. Female were most frequently diagnosed with affective disorders, whereas organic mental disorders and substance use disorders prevail in male.

Interaction channels are special opportunities to improve customer satisfaction by offering a consistent problem-solving experience. Contact center employees are the link between the company and the customer. They are responsible for maintaining an appropriate relationship between the company and the customer. So, they are personally responsible for the customer experience. In this paper, we present an objective evaluation method for evaluating customer-agent interaction, i.e., evaluating the effectiveness of the realization of customer requests from calls. The evaluation method is automatic and does not depend on the relationship between the call center manager and the employees. The motivation for evaluating calls stems from the key performance characteristics of a contact center, of which we particularly emphasize service time, first call resolution, handling time, and others.

K. Ntatsis, Niels Dekker, V. van der Valk, Tom Birdsong, Dženan Zukić, S. Klein, M. Staring, Matthew Mccormick

—Image registration plays a vital role in understanding changes that occur in 2D and 3D scientific imaging datasets. Registration involves finding a spatial transformation that aligns one image to another by optimizing relevant image similarity metrics. In this paper, we introduce itk-elastix , a user-friendly Python wrapping of the mature elastix registration toolbox. The open-source tool supports rigid, affine, and B-spline deformable registration, making it versatile for various imaging datasets. By utilizing the modular de-sign of itk-elastix , users can efficiently configure and compare different registration methods, and embed these in image analysis workflows.

Background: Metabolic syndrome (MetS) denotes a cluster of co-occurring medical conditions associated with regulating hyperglycemia and acute cardiovascular events and complications. The escalating frequency of MetS among individuals afflicted with type 2 diabetes mellitus (T2DM) underscores its burgeoning significance as a critical public health concern and a complex clinical conundrum. Timely identification is imperative to avert the expedited progression of diabetic complications. Objective: To investigate the role of CRP/HDL-C and Monocyte/HDL ratios in predicting MetS in T2DM individuals. Methods: The study was designed as a two-year prospective study and included 80 T2DM patients divided into MetS and non-MetS groups based on MetS development over two years. The patients’ serums were analyzed for complete blood count parameters, lipid profile, and C-reactive protein (CRP). Based on the laboratory test results, Monocyte/HDL-C and CRP/HDL-C ratios were calculated and analyzed. The receiver operating characteristic (ROC) curve and their corresponding areas under the curve (AUC) were used to determine prognostic accuracy. Results: Monocyte/HDL-C ratio and CRP/HDL-C ratio were significantly higher in MetS-T2DM2 than in nonMetS-T2DM (p=0.003 and p=0.029, respectively). The results of ROC curve analysis have shown that the CRP/HDL-C ratio (AUC of 0.695) and Monocytes/HDL-C ratio (AUC of 0.645) can serve as good predictors of MetS in T2DM patients. Conclusion: This study confirms the reliability of the Monocytes/HDL-C and CRP/HDL-C ratios as novel, simple, low-cost, and valuable predictors of MetS development in T2DM.

Andreas Kartakoullis, Nina Slamnik-Kriještorac, Valentin Carlan, Alexandru Vulpe, George Suciu, Marius Iordache, J. Brenes, Giada Landi et al.

In this paper we present VITAL-5G platform, a flexible 5G innovative infrastructure that can host Network Applications (NetApps) to optimize the performance and the efficiency of services in the Transport & Logistics (T&L) sector. It is a complete system that comprises hardware, software

This paper describes influences of heat input on leg size of pulsed GMAW fillet welds of unalloyed steel with thicknesses of 4 mm, in horizontal and overhead position. Varied parameters were welding current and speed, while voltage and current profile were predefined by welding equipment manufacturer. Influence is described through models based on linear regression analysis. Comparison is made between developed models, as well as with those available in literature.

Background: Patients infected by coronavirus disease (COVID-19), caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), display various symptoms and severity of the clinical picture. Thus, the therapy and pathophysiology of this disease are a dilemma for health professionals and scientists. Objective: This paper aims to evaluate the effectiveness of therapeutic protocols (the use of anticoagulants) in the treatment of COVID-19 patients of various severity of the clinical picture by monitoring coagulation markers (PT, INR, aPTT and D-dimer), as well as the impact of the type and number of comorbidities patients had on these markers. Methods: A total of 200 patients with a mild (n=76), moderate (n=70) or severe (n=54) clinical picture was included. Coagulation markers [PT (prothrombin time), INR (international normalized ratio), aPTT (activated partial thromboplastin time), D-dimer] were examined on three occasions: twice during hospitalization and once after hospital discharge. Anticoagulants used intrahospital were fraxiparine, rivaroxaban or unfractionated heparin. Posthospital, patients were taking either rivaroxaban or did not use any anticoagulants. For statistical analysis, SPSS 26.0 and Microsoft Excel 2019 were used, with a level of significance of α=0.05. Nonparametric tests (Kruskal-Wallis, Wilcoxon Signed-Rank and Bonferroni) were applied and effect size (ES) was calculated. Results: Three anticoagulants used intrahospital caused a significant decrease in PT, INR and D-dimer and a significant increase in aPTT, especially in patients with a severe clinical picture, but the ES was the biggest with fraxiparine, then rivaroxaban, and lastly unfractionated heparin. Posthospital, rivaroxaban caused a significant decrease in PT, INR and D-dimer and a significant increase in aPTT, especially in patients with a severe clinical picture. Hypertension was the most common comorbidity in all patients, as well as in patients with a severe clinical picture. There was a statistically significant impact of the number of comorbidities patients had on D-dimer, and none on PT, INR and aPTT, but the highest number of comorbidities was in patients with a severe clinical picture. Conclusion: The use of anticoagulants, especially fraxiparine intrahospital and rivaroxaban posthospital, is justified in most COVID-19 cases as there is a significant correlation between this disease’s pathophysiology and the coagulation process. There is also a positive correlation between the severity of the clinical picture and the number of comorbidities patients have.

Adnan Osmanspahić, Mile Despotović, N. Hadživuković, Jelena Pavlović, Sandra Matović, S. Živanović, Milena Zlatanović, Mile Despotović et al.

Objective. Long-term care represents a series of health and social care services that are provided at home or in an institutional environment to people with reduced functional capacity (reduced physical and/or cognitive abilities) who need support in performing daily activities, and who depend on the help of others for a long time period. The goal of the research was to examine the quality of life of users with long-term health care, with a special focus on comparing the quality of life between people placed institutionally and outside of the institution. Methods. The research was designed according to the principle of a cross-sectional study. In the research, a general questionnaire and a scale for assessing the quality of life Short Form 36 Health Survey (SF-36) were used. Among the statistical tests, the ch2 square test was used. The usual value of p<0.05 was taken as the level of statistical significance. Results. Subjects who were institutionalized had statistically significantly lower values of domains and summary scores of quality of life compared to subjects whose health care took place outside of institutions, whereby the difference was observed in physical functioning (p<0.001), social functioning (p=0.003) and mental health summary score (p=0.015). Conclusion. Users of long-term health care placed in an institution had significantly worse physical functioning, a higher level of limitations due to physical problems, worse general health, a lower level of social functioning, as well as mental health.

S. Živanović, Jelena Pavlović, N. Hadživuković, Olivera Kalajdžić, Ljubiša Kucurski, V. Kulić

Objective. Aging is characterized by the loss of abilities in the psychological and physical sense. Detailed assessment of cognitive status may enable early identification of high-risk patients who are candidates for dementia. The aim of this research was to examine the cognitive status of elderly people over 65 years of age living in the community and potential risk factors that contribute to the onset of dementia. Methods. The research was designed according to the principle of a cross-sectional study. The research used a general questionnaire, subjective and objective assessment of respondents, Mini Kog assessment. The ch2 square test was used for statistical tests. The usual value of p<0.05 was taken as the level of statistical significance. Results. Females (80.2%) had better cognitive status than males (84.6%) (ch2 =0.189; p=0.664). Respondents with the lowest level of education (primary school) had a worse cognitive status (23.5%) compared to 13.3% of respondents with an intermediate level of education (ch2 =9.139; p=0.010). 8.8% of respondents who socialize with friends had a good cognitive score compared to 0% of respondents with a good cognitive score who do not socialize with friends (ch2 =18.243; p=0.000), also, the cognitive status was worse in those respondents who used different aids (75%) versus 17% of those who do not use different aids for their functional mobility (ch2 =8.832; p=0.003). Conclusion. Dementia is present in a high percentage among elderly people. The level of education and the use of aids are potential risk factors for the onset of dementia.

S. Živanović, Jelena Pavlović, N. Hadživuković, Olivera Kalajdžić, Ljubiša Kucurski, V. Kulić, Mile Despotović

Aging implies a process during which changes occur in the function of all organic systems in the human body. For a detailed assessment of the health status of an elderly person, a comprehensive geriatric assessment (CGA) is recommended. CGA is defined as a multidisciplinary diagnostic and therapeutic approach that enables the identification of medical, psychosocial and functional limitations of an elderly person, all with the aim of developing a coordinated plan to improve the health of the elderly person. The aim of this review was to point out the significance, comprehensiveness, applicability and prognostic significance of geriatric assessment based on data from recent literature and by searching available electronic databases. Studies were collected from the electronic databases MEDLINE (via Ovid), Pubmed, COBSON database and Google Scholar database, as well as by manual search of relevant studies cited in the references of key articles. The search for papers as a whole is limited to the English language. All studies that used a comprehensive geriatric assessment in their methodology, in elderly people over 65 years of age, were included. CGA is very important for the elderly, for their families, health systems of countries, health professionals as well as the social community. Interventions resulting from a CGA are one way to improve the performance of activities of daily living in elderly patients. CGA has numerous advantages in practice, it is comprehensive, applicable, economically relatively acceptable and as such can be routinely implemented at different levels of health care. CGA has a high prognostic significance for the early detection of multimodal problems in the geriatric population.

A. Šljivo, Lejla Brigić, A. Abdulkhaliq, Ilma Dadić, Leopold Reiter, I. Sirucic, Mohammed Abdulkadir, Ahmed Mulać

Background: Increasing evidence indicates that COVID-19 may result in cardiac issues in certain individuals, such as myocarditis, arrhythmias, and heart failure. Ongoing research on echocardiographic manifestations is still limited. Objective: To investigate the incidence and patterns of left and right ventricular dysfunction in COVID-19 patients. Methods: This study retrospectively observed COVID-19 patients admitted to the Clinical Center of University of Sarajevo during the third wave, with a particular focus on cardiac evaluations. Results. Our patients, predominantely male 155 (72.4%), with a mean age of 66.2±11.4, having hypertension 86 (40.1%), diabetes mellitus 61 (28.5%), hyperlipidemia 144 (67.3%), were active smokers 87 (40.6%), had family history of cardiovascular diseases 123 (57.5%) and were COVID-19 positive 95 (44.4%), presented because of chest pain 78 (36.4%), dyspnea 103 (48.1%), palpitations 67 (31.3%), fatigue 106 (49.5%) and peripheral oedema 30 (14.0%). COVID-19 patients reported much higher symptoms of dyspnea (65 (68.4%) vs 38 (31.9%)) and fatigue (73 (76.8%) vs 33 (27.7%)) than COVID-19 negative patients. On the initial laboratory report, COVID-19 patients had a significantly (p<0.05) higher mean score of C-reactive protein (24.0±4.8 vs. 6.0±2.1), D-dimer (1.6±2.5 vs 0.8±0.6), ALT (94.8±17.2 vs 36.5±19.9) and creatinine (128.0±80.8 vs. 93.4±40.1) when compared to COVID-19 negative patients. COVID-19 patients had enlarged left atrium diametes (31.6±5.6 vs 27.5±5.3), enlarged left ventricular diameter both in systole (27.9±18.1 vs 23.3±16.3) and diastole (39.3±24.1 vs 34.9±22.7), reduced left ventricular ejection fraction (53.5±9.2 vs 59.8±4.3) and elevated right ventricular systolic pressure (37.0±16.4 vs 35.1±8.6). Conclusion. COVID-19 patients had enlarged left atrium, enlarged systolic and diastolic left ventricular diameter, reduced left ventricular ejection fraction and elevated right ventricular systolic pressure.

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