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Background: Globally, life expectancy is increasing, leading to an equal proportion of elderly and young individuals, which carries extensive implications. In Bosnia and Herzegovina (BiH), the average age at death in 2021 was 77 years, positioning BiH in the middle of the global list of average life expectancy. Current studiesinvestigate whether the prevalence of psychiatric disorders increases or decreases with age, but results are inconsistent regarding the role of age.There is no prior research on mental disorders in the elderly population in BiH. The experience of the previous war in BiH and the post-war complex “transitional period” have been associated with specific challenges to the mental health of this population, inspiring our research topic. Objective: The aim of this study was to investigate the psychiatric morbidity in hospitalized individuals aged≥55 years. Methods: The sample consisted of all patients over age 55 treated at the Department of Psychiatry in Tuzla between January 2018 and December 2020 (N=637), divided into four age categories. Data were obtained from medical records, and for research purposes, a specific questionnaire was constructed. Results: The predominant psychiatric morbidity stemmed from the category of affective disorders, most common within the “55-64 years” age group, while organic mental disorders were more prevalent in other age groups.Substance use disorders were present in patients aged “55-64 years”, with a sharp decline in their prevalence in older age. Female participants had a significantly higher prevalence of affective, psychotic, neurotic, and stress-related disorders, whereas male participants exhibited an increased prevalence of organic mental and substance use disorders. Conclusion: In total sample, the most prevalent diagnoses belong to the category of affective disorders. Female were most frequently diagnosed with affective disorders, whereas organic mental disorders and substance use disorders prevail in male.

Interaction channels are special opportunities to improve customer satisfaction by offering a consistent problem-solving experience. Contact center employees are the link between the company and the customer. They are responsible for maintaining an appropriate relationship between the company and the customer. So, they are personally responsible for the customer experience. In this paper, we present an objective evaluation method for evaluating customer-agent interaction, i.e., evaluating the effectiveness of the realization of customer requests from calls. The evaluation method is automatic and does not depend on the relationship between the call center manager and the employees. The motivation for evaluating calls stems from the key performance characteristics of a contact center, of which we particularly emphasize service time, first call resolution, handling time, and others.

Konstantinos Ntatsis, Niels Dekker, Viktor van der Valk, Tom Birdsong, Dženan Zukić, S. Klein, M. Staring, Matthew Mccormick

—Image registration plays a vital role in understanding changes that occur in 2D and 3D scientific imaging datasets. Registration involves finding a spatial transformation that aligns one image to another by optimizing relevant image similarity metrics. In this paper, we introduce itk-elastix , a user-friendly Python wrapping of the mature elastix registration toolbox. The open-source tool supports rigid, affine, and B-spline deformable registration, making it versatile for various imaging datasets. By utilizing the modular de-sign of itk-elastix , users can efficiently configure and compare different registration methods, and embed these in image analysis workflows.

K. Plis, M. Niedziałkowska, T. Borowik, Johannes Lang, M. Heddergott, Juha Tiainen, Aleksey Bunevich, N. Šprem et al.

Background: Patients infected by coronavirus disease (COVID-19), caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), display various symptoms and severity of the clinical picture. Thus, the therapy and pathophysiology of this disease are a dilemma for health professionals and scientists. Objective: This paper aims to evaluate the effectiveness of therapeutic protocols (the use of anticoagulants) in the treatment of COVID-19 patients of various severity of the clinical picture by monitoring coagulation markers (PT, INR, aPTT and D-dimer), as well as the impact of the type and number of comorbidities patients had on these markers. Methods: A total of 200 patients with a mild (n=76), moderate (n=70) or severe (n=54) clinical picture was included. Coagulation markers [PT (prothrombin time), INR (international normalized ratio), aPTT (activated partial thromboplastin time), D-dimer] were examined on three occasions: twice during hospitalization and once after hospital discharge. Anticoagulants used intrahospital were fraxiparine, rivaroxaban or unfractionated heparin. Posthospital, patients were taking either rivaroxaban or did not use any anticoagulants. For statistical analysis, SPSS 26.0 and Microsoft Excel 2019 were used, with a level of significance of α=0.05. Nonparametric tests (Kruskal-Wallis, Wilcoxon Signed-Rank and Bonferroni) were applied and effect size (ES) was calculated. Results: Three anticoagulants used intrahospital caused a significant decrease in PT, INR and D-dimer and a significant increase in aPTT, especially in patients with a severe clinical picture, but the ES was the biggest with fraxiparine, then rivaroxaban, and lastly unfractionated heparin. Posthospital, rivaroxaban caused a significant decrease in PT, INR and D-dimer and a significant increase in aPTT, especially in patients with a severe clinical picture. Hypertension was the most common comorbidity in all patients, as well as in patients with a severe clinical picture. There was a statistically significant impact of the number of comorbidities patients had on D-dimer, and none on PT, INR and aPTT, but the highest number of comorbidities was in patients with a severe clinical picture. Conclusion: The use of anticoagulants, especially fraxiparine intrahospital and rivaroxaban posthospital, is justified in most COVID-19 cases as there is a significant correlation between this disease’s pathophysiology and the coagulation process. There is also a positive correlation between the severity of the clinical picture and the number of comorbidities patients have.

This paper describes influences of heat input on leg size of pulsed GMAW fillet welds of unalloyed steel with thicknesses of 4 mm, in horizontal and overhead position. Varied parameters were welding current and speed, while voltage and current profile were predefined by welding equipment manufacturer. Influence is described through models based on linear regression analysis. Comparison is made between developed models, as well as with those available in literature.

T. Uzunović, Eray A. Baran, İlkay Turaç Özçelik, Minoru Yokoyama, Tomoyuki Shimono, Asif Šabanović

Owing to the increasing engagement of service robots in everyday life, significant requirements are imposed on their control systems to ensure safe interaction between robots and humans. The stiffness of the motion executed by the service robots is not high, as with industrial robots, but has to be variable depending on the defined task. Therefore, a service robot needs to have soft actuation, delivering “human-like” motion dependant on the interaction force between the robot and its environment. Such an operation requires switching from the trajectory tracking (position control) mode to the interaction (force control) mode, and vice versa. Conventional control methods, based on hybrid position/force control, or switching between a position and force controller, may fail short in these cases. Thus, we have previously proposed a new control method, denoted as universal motion controller, that merges the position and force control into a single control structure. The control method is elaborated in this article, and its experimental validation is presented for the first time for multi-degree-of-freedom systems.

Background: Consuming a diet rich in natural foods that include oilseed products containing bioactive compounds and a diverse array of fatty acids is not just a dietary choice; it is a critical element of maintaining human health. Objective: This paper aims to review the current state of knowledge on minor bioactive compounds in vegetable cold pressed oils, these are substances that are found in small amounts in vegetable cold pressed oils. Methods: Intended as an indispensable resource, this review is designed to empower medical professionals in the fields of integrative medicine, nutrition, and dietetics. Results and Discussion: Cold-pressed oils extracted from various plant sources have emerged as vital allies in the battle against inflammation-related diseases, offering a versatile range of valuable compounds. These compounds contribute to the oils' multifaceted properties, which encompass potent anti-inflammatory, antioxidant, and anticancer effects, greatly enhancing their nutritional significance. This brief review delves deep into the intricate composition of cold-pressed oils, with a specific focus on the often overlooked but highly influential minor bioactive compounds, including phytosterols, phospholipids, tocols, phenols, squalene and pigments. Intended as an indispensable resource, this review is designed to empower medical professionals in the fields of integrative medicine, nutrition, and dietetics. It equips them with a wealth of knowledge to guide consumers in making informed choices when incorporating cold-pressed oils into their dietary plans, tailored to their individual health needs.. Conclusion: This paper highlights the importance of cold-pressed oils as a source of various minor bioactive compounds that have the potential to promote human health and prevent or manage a range of diseases. The findings presented in this paper serve as a valuable resource for medical professionals in the field of integrative medicine, nutrition, and dietetics, as well as for consumers looking to make informed choices about their dietary and health needs.

M. Topčagić, F. Julardžija, Arzija Pašalić, A. Šehić, Adnan Beganovic, Hasan Osmić, Enis Tinjak, Adnan Huskić

Background: Radiotherapy is one of the primary treatment options in cancer management, together with surgery and chemotherapy. Radiation therapy is technologically complex discipline involving professionals with various specialties, and using high energy radiation in treatment of wide range of different cancer types. Technical complexity, increasing number of patients, large workload, and delivery of radiation therapy treatment with lack of human, technical and financial resources in low and middle income countries creates environment with great potential to develop incidents. Emerging need of modern radiation therapy is to develop preventive approach to risk management i to improve the patient safety. Objective: The objective of this research is to identify and assess risk associated with radiation therapy practice in Bosnia and Herzegovina. Methods: An anonymous, voluntary electronic on-line radiation therapy incident reporting system (IRS) was created. IRS consists of four sections containing questions about working environment, incident occurrence, root causes and contributing factors, and incident severity assessment. Data collected using IRS were used to create taxonomy of incidents in radiation therapy. Risk assessment was made using Risk Matrix method. Research was made using the data collected from first 60 incidents reported to IRS. Results: Based on probability and frequency of incident occurrence and severity of consequences, it was assessed that 41.7% of incidents had low risk level (L), 50% of incidents had moderate risk level (M), and 8.3% of incidents had high risk level (H). Radiation therapy risk profile based on risk assessment results clearly shows that incidents with low frequency, low occurrence probability, but high consequences severity level have highest level of risk. Conclusion: The results of this research confirm that the electronic on-line radiation therapy IRS allows the identification and classification of the most significant risk factors in radiotherapy and prevention of serious incidents occurrence.

M. Petronijević, Č. Milosavljević, B. Veselić, S. Huseinbegović, B. Perunicic

Application of a discrete time (DT) sliding mode controller (SMC) in the control structure of the primary controller of a three-phase LCL grid inverter is presented. The design of the inverter side current control loop is performed using a DT linear model of the grid inverter with LCL filter at output terminals. The DT quasi-sliding mode control was used due to its robustness to external and parametric disturbances. Additionally, in order to improve disturbance compensation, a disturbance compensator is also implemented. Also, a specific anti-windup mechanism has been implemented in the structure of the controller to prevent large overshoots in the inverter response in case of random disturbances of grid voltages, or sudden changes in the commanded power. The control of the grid inverter is realized in the reference system synchronized with the voltage of the power grid. The development of the digitally realized control subsystem is presented in detail, starting from theoretical considerations, through computer simulations to experimental tests. The experimental results confirm good static and dynamic performance.

K. Nnoli, Fahrudin Delić, S. Kettemann

The energy transition towards increased electric power production from renewable energy (RE) resources creates new challenges to ensure the stability of power grids. In conventional power grids voltage fluctuations can be controlled locally. Here, it is explored whether this may be changed by the energy transition. It is well established that the increase of RE resources in power grids increases the amplitude of frequency deviations and the velocity with which these deviations spread throughout the power grid. However, its effect on voltage dynamics and propagation has not been systematically studied. Here, a systematic study is carried out of the transients of voltage amplitude, phase and frequency deviations due to local contingencies in dependence on system inertia, heterogeneity and topology. The 3rd order dynamic power grid model is studied numerically and analytically and compared with real grid simulations for the Nigerian (330 kV) power grid and other grid models, using DigSILENT PowerFactory software. A quantitative analysis of the parametric dependence of the velocity with which a disturbance propagates throughout the grid and of the period of oscillations of the frequency and voltage transients is provided. Beating patterns are found in the transients and are identified as footprints of the location of the fault bus, as caused by multiple reflections of propagating disturbances from the grid boundary. These may result in interarea oscillations. It is confirmed that voltage deviations remain local for realistic ranges of parameters, but that it can propagate by literally surfing on the frequency deviation wave. However, it is found that this no longer holds true when the electrical power in the grid approaches its critical value beyond which no stationary solution exists. Furthermore, time dependent second moments of the geodesic distance weighted with frequency deviations $S_{\delta \omega }(t)$ and voltage deviations $S_{\delta V}(t)$ , respectively are evaluated, confirming a ballistic disturbance propagation in homogeneous model grids. However, in real grid simulations, a linear time dependence of $S(t)$ is observed, indicating a diffusive propagation due to multiple scattering from the inhomogeneities in these power grids.

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