The ideological underpinnings of the Great Replacement Theory, which frames Muslims as a threat to Europe, originated in Serbia and emboldened a wider narrative of anti-Muslim hate across Western milieus. The othering of Bosnian Muslims (Bosniaks), an autochthonous ethnic group in Southeastern Europe, has contributed to the normalization of the alienation of Muslims throughout Europe, engendering Educational Displacement —an internalized sense of invisibility and devaluation within targeted individuals, diminishing their participation and trust in the societal institutions. In this complex socio-political and historical context, Bosniaks have nonetheless chosen to principally champion interfaith coexistence, offering an instructive and community-based model of resilience to hate and violence. The study investigates the Bosniaks’ affinity for coexistence by examining the underexplored case of interfaith solidarity and entente between Muslims and Jews in Bosnia and Herzegovina from 1540 to the present.
Purpose – Money laundering is one of the most widespread phenomena in the financial world which is seriously threatening the integrity of system and representing a significant risk to a country’s economic development, as well as its progress in geopolitical and infrastructural terms. In recent years, Bosnia and Herzegovina (B&H) has frequently appeared in various studies, articles, and media publications as one of the countries where this phenomenon is becoming more and more popular, and now we are witnessing that our country is being referred to as a “paradise” for money laundering. This research will focus on the role of Bosnia and Herzegovina’s financial and business sectors, analyzing their role in the money laundering process and attempting to light up on some of the most common methods related to this phenomenon in Bosnia and Herzegovina. Methodology/Research Approach – The research will be conducted using both qualitative and quantitative methods. A detailed analysis of secondary sources of information will be carried out, along with the collection of primary data on the given topic. A review of previously published works and relevant literature will also be conducted. Limitations/Implications – The topic of this research is relatively unexplored and does not receive enough attention in the existing literature/studies, which presents a challenge in gathering needed data. The high unavailability of key information may limit the depth of analysis and accuracy of conclusions. Given the limited data sources, the research has been conducted in accordance with the available information from the approximately last 10 years, which may affect the scope and validity of the findings. Practical Implications – This research contributes to a better understanding of the money laundering phenomenon, with a particular focus on the role of the business and financial sectors in Bosnia and Herzegovina. The research results can help in developing more effective strategies to combat money laundering, thereby reducing the harmful economic and social consequences that this phenomenon brings. Practical recommendations may include improvements in legal provisions and strengthening oversight and control in the business and financial sectors. Originality – This research provides an original perspective on money laundering in the context of Bosnia and Herzegovina’s business and financial sectors and encourages further discussions and deeper investigations. Previous studies can mostly be characterized as reviews, whereas this paper brings together all relevant macroeconomic variables and variables of interest in this case, offering a deeper insight into and addressing a previously unexplored area.
The future circular $e^+ e^-$ collider (FCC-ee) stands out as the next flagship project in particle physics, dedicated to uncovering the microscopic origin of the Higgs boson. In this context, we assess indirect probes of the Minimal Supersymmetric Standard Model (MSSM), a well-established benchmark hypothesis, exploring the complementarity between Higgs measurements and electroweak precision tests at the $Z$-pole. We study three key sectors: the heavy Higgs doublet, scalar top partners, and light gauginos and higgsinos, focusing on the parameter space favored by naturalness. Remarkably, the Tera-$Z$ program consistently offers significantly greater indirect sensitivity than the Mega-$h$ run. While promising, these prospects hinge on reducing SM uncertainties. Accordingly, we highlight key precision observables for targeted theoretical work.
Analysis of conversions between compressional and shear waves is a workhorse method for constraining crustal and lithospheric structure on Earth; yet, such converted waves have not been unequivocally identified in seismic data from the largest events on the Moon, due to the highly scattered waveforms of shallow seismic events. We reanalyze the polarization attributes of waveforms recorded by the Apollo seismic network to identify signals with rectilinear particle motion below 1 Hz, arising from conversions across the crust‐mantle boundary. Delay times of these converted waves are inverted to estimate crustal thickness and wavespeeds beneath the seismometers. Combined with gravimetric modeling, these new crustal thickness tie‐points yield an updated lunar crustal model with an average thickness of 29–47 km. Unlike previous models, ours include explicit uncertainty estimates, offering critical context for future lunar missions, geophysical studies, and predicting 15–36 km crust at Schrödinger and 29–52 km at Artemis III sites.
Brewer’s spent grain (BSG), the most abundant by-product from breweries, is mainly discarded or used as animal feed. However, to increase the brewing sustainability, biotechnological utilization of BSG is a much preferred solution. This study examined the fermentation of BSG, composed of old wheat bread and barley malt, by metabolic activity of Saccharomyces cerevisiae on both hydrolyzed and non-hydrolyzed media. Enzymatic hydrolysis with Viscozyme® W FG for 6 h was selected as the most effective and was used in the further research step to prepare the hydrolyzed BSG-based medium. Both media supported almost uniform yeast growth (numbers of S. cerevisiae cells was about 8 log10 CFU/g) in an acidic environment (pH value was about 5), but fermentation of hydrolyzed BSG resulted in 20% higher sugar consumption and 10% higher total titratable acidity. These findings underscore the potential of enzymatic pretreatment to improve fermentation performance. The adaptability of S. cerevisiae and the fermentability of both substrates suggest promising potential for scalable BSG valorization strategies in circular food systems.
We introduce ManifoldMind, a probabilistic geometric recommender system for exploratory reasoning over semantic hierarchies in hyperbolic space. Unlike prior methods with fixed curvature and rigid embeddings, ManifoldMind represents users, items, and tags as adaptive-curvature probabilistic spheres, enabling personalised uncertainty modeling and geometry-aware semantic exploration. A curvature-aware semantic kernel supports soft, multi-hop inference, allowing the model to explore diverse conceptual paths instead of overfitting to shallow or direct interactions. Experiments on four public benchmarks show superior NDCG, calibration, and diversity compared to strong baselines. ManifoldMind produces explicit reasoning traces, enabling transparent, trustworthy, and exploration-driven recommendations in sparse or abstract domains.
Menopause represents an inevitable transition in a woman’s life, presenting with vasomotor symptoms, mood disorders, sleep difficulties, and prolonged risks such as osteoporosis and cardiovascular diseases. Hormone replacement therapy emerged as the cornerstone of menopausal management, particularly for alleviating symptoms and preventing postmenopausal osteoporosis. However, findings from the Women’s Health Initiative (WHI) study in 2002 highlighted increased risks of breast cancer, cardiovascular disease, and stroke associated with hormonal replacement treatment, leading to a significant global decline in its usage. Consequently, numerous women were deprived of essential therapy, endangering their health and quality of life. This review presents the findings of the WHI study, discusses its methodological errors, and evaluates its benefits and harms. We explore landmark studies that have reestablished the benefits and risks of hormone replacement therapy over the past two decades. Guidelines supported by these findings are presented in this review. Despite advancements, public perception of hormone replacement treatment remains influenced by outdated findings, limiting its utilization in many regions, especially in developing countries. Our objective is to provide evidence that misconceptions about hormone replacement therapy significantly impact women’s general health and quality of life, as well as to clarify the short-term and long-term impacts of hormone replacement therapy. We conclude that hormonal replacement treatment is effective and safe when administered according to established guidelines. Access to information, coupled with knowledgeable physicians who consistently interact with women, is as vital as the contributions of menopause healthcare specialists. Conflicting information from outdated professionals can likely lead to treatment failure in patients. Keywords: menopause, women’s health, estrogens, progestins, quality of life
Procedural modeling methods are used to automatically generate virtual scenes. There is a large number of available top‐down methods for generating partial content for specific purposes. However, little research was done on enabling the generation of content in the presence of manually modeled elements, from the bottom‐up direction, or without significant assistance from the user. No existing approach provides a platform that can combine the results of different methods, which leaves them isolated. This paper presents an integration approach that generates complete virtual space organizations by combining the usage of top‐down and bottom‐up procedural generation of content, with support for the placement of manually modeled content. The integration is made possible by using shape conversion to match the input and output shape types of different methods. The evaluation of the proposed approach was performed on a 2D polygon dataset by using four different scenarios, validating that it works as intended. Additional testing was performed by using a case study of organizing 3D virtual space around the manually modeled element of virtual heritage Tašlihan to demonstrate all capabilities of the integration approach and the different outputs depending on the level of user interaction and the desired results.
Background Acute cholecystitis (AC) is a frequent surgical emergency associated with significant variability in clinical outcomes and hospital length of stay (LOS). Early identification of patients at risk for prolonged hospitalization can improve triage and resource planning. Inflammatory markers such as C-reactive protein (CRP), white blood cell count (WBC), and total bilirubin (TBil), along with biliary complications like choledocholithiasis and Mirizzi syndrome, may have prognostic value. Materials and methods This retrospective study included 150 patients who underwent cholecystectomy for AC at the Department of General and Abdominal Surgery, University Clinical Centre Tuzla, Tuzla, Bosnia and Herzegovina, between January 1, 2024, and January 31, 2025. Demographic, laboratory, and intraoperative data were collected. Receiver operating characteristic (ROC) analysis identified optimal cut-offs for inflammatory markers predicting prolonged LOS (≥7 days). Multivariate linear regression was used to assess independent predictors, including CRP, WBC, TBil, and intraoperative findings. Results We found that CRP was significantly higher in patients with prolonged LOS and demonstrated the highest predictive accuracy, with an area under the curve (AUC) of 0.733 (95% CI: 0.630-0.835), followed by TBil and WBC. In multivariate analysis, only CRP ≥110.5 mg/L (p<0.001), the presence of choledocholithiasis in 26 patients (17.3%; p=0.010), and Mirizzi syndrome in seven patients (4.7%; p=0.017) remained significant predictors. WBC and TBil lost significance after adjustment. Conclusion CRP is the most reliable independent laboratory predictor of prolonged LOS in AC. The presence of choledocholithiasis and Mirizzi syndrome further contributes to extended hospitalization. These factors should be considered in early clinical risk assessment.
Background/Objectives: This research reports the synthesis and evaluation of novel charged thienobenzo-triazoles as non-selective cholinesterase inhibitors (AChEs and BChEs), their anti-inflammatory properties, and a computational study. Methods: Fifteen derivatives were created through photochemical cyclization and quaternization of the triazole core. The compounds were tested for AChE and BChE inhibition. They showed greater potency and selectivity toward BChE. Results: The most potent compound, derivative 14, inhibited BChE with an IC50 of 98 nM, while derivative 9 also displayed significant anti-inflammatory activity by inhibiting LPS-induced TNF-α production (IC50 = 0.66 µM). Molecular docking revealed that triazolinium salts form key π-π and electrostatic interactions within enzyme active sites. In silico predictions indicated favorable ADME-Tox properties for compounds 9 and 11, including low mutagenicity and moderate CNS permeability. Conclusions: These findings highlight the potential of new charged triazolinium salts as peripherally selective cholinesterase inhibitors with additional anti-inflammatory potential.
Psychological studies on close relationships have often overlooked cultural diversity, dynamic processes, and potentially universal principles that shape intimate partnerships. To address the limited generalizability of previous research and advance our understanding of romantic love experiences, mate preferences, and physical attractiveness, we conducted a large-scale cross-cultural survey study on these topics. A total of 404 researchers collected data in 45 languages from April to August 2021, involving 117,293 participants from 175 countries. Aside from standard demographic questions, the survey included valuable information on variables relevant to romantic relationships: intimate, passionate, and committed love within romantic relationships, physical-attractiveness enhancing behaviors, gender equality endorsement, collectivistic attitudes, personal history of pathogenic diseases, relationship quality, jealousy, personal involvement in sexual and/or emotional infidelity, relational mobility, mate preferences, and acceptance of sugar relationships. The resulting dataset provides a rich resource for investigating patterns within, and associations across, a broad range of variables relevant to romantic relationships, with extensive opportunities to analyze individual experiences worldwide.
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