UDK 631.8(497.6 Čapljina) The concentration and form of some metals and metalloids in soil is governed by many chemical and physical properties of soil as pH, redox, Fe, Al ions and soil composition. The paper studied presents influence of chemical soil properties, environment conditions and selenium fertilization rate applied on ions status of zinc, cadmium, selenium and iron in soil and plant material, as well as specific adsorption of these ions in two different maize hybrids. The study was conducted at the farm Vita-Vi Višići (Čapljina). The experiment design was a completely randomized design with two hybrids, four different fertilization treatments in four replications. The experimental area was implemented standard agricultural management practices of preparation, tillage, fertilization, application of protective agents. Hybrid NP Pako is selected in order to achieve a high yield, and M34 hybrid for quality yield. The test results and statistical analysis revealed no significant difference in the yield of hybrids combined with different fertilization treatments. Accumulation of selenium, zinc, cadmium and iron in upper ground plant part of maize was not affected by fertilization treatments or selected hybrid. The highest yield was achieved by hybrid M34 Pioneer of 37.6 t ha- 1and the highest yield was obtained in application of third fertilization treatment 20 kg NaSeO4ha-1, but without statistically significant differences comparing to other hybrid or applied treatments. The highest content of selenium in the plant was found in hybrid NP PAKO 0.06 mg Se kg-1 of dry matter of maize applying the fourth liquid fertilization treatment (20 kg Na2SeO4ha-1) but also without statistically significant difference comparing to other hybrid or fertilization treatment. Content of zinc, cadmium and iron in soil or plant material had not shown significant differences due to the applied fertilization or used maize hybrids, but some fluctuations were observed. Selenium fertilization did not have a limiting effect on the formation of the yield and tested elements, but its mobility and availability in soil and plant depends also on other factors as soil properties and climatic conditions of growing season.

UDK 631.4(497.6) Multi-purpose land evaluation is a method of assessing the quality and value of the land in the service planning and land management, and is the fundamental basis for the development and optimum use of land in general. The subject of the study was evaluation of multi-purpose suitability of land for agricultural use was made according to the Regulations on the uniform methodology for the classification of agricultural land in the class (Official Gazette of the Federation of B&H, No. 43/11), using FAO assessment methodology (FAO, 1976; Brinkman and Smyth, 1973). Based on the results of research was created a database and map of suitability of agricultural land for growing different plants in agriculture vegetable (gardening); arable farming (annual crops); fruits (fruits growing); wine-growing (viticulture) and grassland (pastures and meadows). It was determined the priority of agricultural use as well as dedicated map (1:200 000), which shows the distribution of 36 recommended agricultural and economic programs in the Federation of Bosnia and Herzegovina. It was found that the largest area of 429,685.4 ha or 40.45% of agricultural land in the Federation of Bosnia and Herzegovina is suitable for agricultural economic program of grassland. Follow the other agricultural economic programs: fruits-grassland 123,996.4 ha or 11.67%; then fruits-vegetable-annual crops with an area of 89,384.7 ha (8.41%) and grassland-fruits-vegetable occupying 66.562 ha or 6,26% and grassland-vegetable-annual crops with an area 62,136.3 ha (5.85%). Other agricultural economic programs individually occupy an area of less than 4% of land. We believe that the information obtained through this project contribute to the overall development of agriculture in the Federation of Bosnia and Herzegovina, especially in terms of creating a proper and balanced concept as part of sustainable land management and reasonable land use policy.

375 BRANKO CESNIK (1956–2007) Branko Cesnik (1956-2007) earned MBBS in 1978 and MD in 1995. He was an Australian pioneer and an international leader in Health Informatics (1-4). Branko graduated as a doctor from Monash University. Following his graduation he worked in training posts in accident and emergency medicine and renal medicine in Australia before spending time working in South Africa. In 1988 Branko was appointed as a Senior Lecturer with the Department of Community Medicine and General Practice at Monash University. Under the visionary leadership of Professor Neil Carson AO, Branko went on to establish the first research and education unit for Medical informatics in any of the medical school in Australia. Branko’s research focused on innovative ways to use information technology to support medical education and clinical care. Branko’s work in medical education innovation received the Monash University Silver Jubilee Teaching Prize in 1993. In 1995 Branko was appointed as Associate Professor at Monash University and later Branko and Wendy and the members of their unit accepted an invitation to become part of the new Monash Institute for Health Services Research, established by the late Professor Chris Silagy AO. At the institute Branko continued his research activity on the establishment of successful postgraduate training programs for health professionals in health informatics. His vision for the use of IT in health care preceded the widespread development of the World Wide Web and the hypermedia applications which were to appear in the mid1990s. Branko fostering the development of health informatics especially in Australia and the Asia Pacific Region. In 1991 Branko was one of the founders of the Health Informatics Society of Australia. Since its establishment the Society has held an annual health informatics conference which has been instrumental in raising the profile of health informatics and facilitating the development of this discipline in Australia. In 1994 Branko cofounded the Asia-Pacific Association for Medical Informatics becoming its second President from 1997-2000. In 1997 he was responsible for bringing the second conference of the Asia Pacific Association for Medical Informatics to Australia. In 1999 Branko became a foundation Fellow of the Australian College of Health Informatics. Branko was the second President of the Australian College of Health Informatics from 2001-2003. In 2001 Branko was elected as Vice-President of IMIA, a mark of the level of respect that he engendered among his peers at an international level. His work helped to ensure that the 2007 conference of the MEDINFO, in Brisbane. He was involved especially in supporting the evaluation of health computing in Australian general practice. In recent years Branko also worked for Australia’s National Health and Medical Research Council as a member of the Health Advisory Committee and as Chair of the Information Management Framework Committee. Branko was also appointed by the Australian Health Ministers Council as a member of the National Health Information Group, which is leading the development of electronic health records in each state and territory. Branko, also, worked as a clinician in the Emergency Department of the Knox Private Hospital in Wantirna for many years. In August 2005 Branko’s leadership and life work was honored with the award of Life Membership of the Health Informatics Society of Australia, and Life Membership of the IMIA. These are rarely bestowed honors and they reflect the esteem of Branko’s peers in Australia and around the world.

UDK 631.164(497.6) The main act to consider the value of land from the perspective of various sectors and their needs (urban planning, agriculture etc.) in the Federation of B&H is the Decree on unique methodology for preparation of the spatial planning documents (Official Gazette of the Federation of B&H, No. 63/04 and No. 50/07), which prescribes the obligation of making the Land capability study as a segment of spatial basis. Land capability study projects are being implemented by the Institute of Soil, Agro chemistry and Melioration (PAM) of the Faculty of Agricultural and Food Sciences University of Sarajevo. By using defined soil bonity categories, land capability study defines the natural potential of soils in terms of agricultural production and food production, and defines the zones for various land use types. From the rational land use point of view, it means adequate spatial planning, urban development and environmental protection. This paper aims to present the importance, characteristics as well as use of the Land capability study at the municipality level using municipalities of Tuzla Canton as example. Agricultural areas of on the territory of five municipalities in Tuzla Canton (Gradacac, Gracanica, Kalesija, Zivinice, Sapna) account for 44,356.1 ha or 42.6% of the total area. Represented in these areas are soil bonity categories that range from II to VII. The first four bonity categories that are determined exclusively as agricultural land account for 28,739.91 ha or 63.1% of the total area. Within this group, the most represented is the IVb category with 17,229.8 ha. The best quality bonity categories II and III account for 7,514.3 ha or 16.5% of the total area. Analysis of the orthophoto images has identified a significant dynamics of change in space in the period 2008-2012 in four municipalities (Gradacac, Kalesija, Zivinice, Gracanica). Analysis has established that artificial areas (developed) increased by 737 ha, agricultural areas without orchards decreased by 1,136.72 ha, while the areas under orchards increased by 283.13 ha. The largest expansion of developed areas and settlements was recorded within the bonity categories IVb (47% of the total change) and III (27%).

UDK 631.4:551.583(497.6) The value of the landscape in the karst region of Bosnia and Herzegovina (B&H) is the foundation of its existence and the key role in its appearance and formation is played by geomorphology and the soil. Through history the man has created a „cultural landscape” which is completely adapted to the natural conditions. He further enriches the space and makes it more appealing. Soils in B&H karst are extremely heterogeneous and form a real pedological mosaic. Found on the Mesozoic sediments of limestone and dolomite of the Middle and Upper Jurassic and Early and Late Cretaceous are Bare rocks (barren land), Rocky grounds (Lithosol), Limestone-dolomite Black soil (Calcomelanosol) and Brown soil on limestone and dolomite (Calcocambisol). A specificity of these rocks are the screes that are transported down the hillside. A series may occur on them in which, if shale materials are contained, Rendzina appears as a calcareous soil. In addition to the above mentioned limestone and dolomite, there are marly limestones of Jurassic and Cretaceous age and Quaternary sediments on which Alluvial soils (Fluvisol) developed as well as the soils of karst fields which are sometimes very porous and skeletal and sometimes heavy and clayey on impermeable substrate (hydromorphic soils). The paper will provide an overview of characteristic soil types in the Sub-Mediterranean upper and lower karst region of B&H taking into account a range of properties that make them sensitive and vulnerable within the ecosystem. These should include a lack of water on the surface and large fluctuations in the amount of water during the rainy and dry seasons and whimsicality of climate in general, which has a huge impact on the state of biodiversity and human lives in this region.

UDK 631.4:551.435.8(497.6) Natural characteristics of karst areas (lack of water on the surface, scarce soil and vegetation) are rather specific and because of them they are often viewed as unsuitable for human habitation. They are often described as inhospitable and passive areas, and Aley (1992) states that karst areas in America are correlated with areas of rural poverty. A large part of Bosnia and Herzegovina consists of karst areas (karst land extending northwest-southeast) which on average are quite sparsely populated. The scarcity of nature, and especially of soil functions in terms of agriculture, as well as the previous period of industrial development caused depopulation which became particularly apparent after the recent war. This contributed to the fact that in some karst areas population has been drastically reduced, in some places by more than 60%, which affects the condition of land cover and land use as well as change in functions of soil in the ecosystem. Given the fact that the soil formation process on karst terrain is very slow (these are mainly shallow and skeletal soils) and in view of the importance of soil and its multi- functionality, this paper is aimed at analyzing the extent and nature of changes which occurred in land cover and in land use in this part of BiH, namely at analyzing the causes and effects. In order to be able to make such analysis, we used land cover databases, aerial photographs as well as orthophoto maps of the terrain.

Introduction: Surgical and medical treatments of nasal obstruction are a common parts of otolaryngologist practice. The definitive treatment of deviated nasal septum is septoplasty. Aim: In this study was to evaluate the values of subjective parameters, and active anterior rhinomanometry parameters prior and three months after the septoplasty. Patients and Methods: We analyzed the subjective parameters (“NOSE” scale), the active anterior rhinomanometry parameters according to International Committee on Standardization of Rhinomanometry, on 40 patients. Thirty healthy adult volunteers participated belonged to the control group. None of the patients or healthy volunteers had previous history of nasal surgery or active rhinological disease. Results: The post-operative improvement in symptoms of nasal obstruction obtained in 92,5% patients and improvement parameters of the active anterior rhinomanometry in 42,5% patients. Conclusion: The correlation between the findings with rhinomanometry and subjective sensation of nasal patency remains uncertain. There still seems to be only a limited argument for the use of rhinomanometry for quantifying surgical results. Three months postoperative findings are very early results to interpret the permanent effects.

UDK 631.41:631.482(1-751.2 Una)(497.6) The paper presented results of a comparison of alluvial soils of different land use at two sites within the National Park "Una". The sites were related to a natural meadow (BUK) and artificial meadow (KLISA). The main objective of the research, in addition to the physical and chemical parameters of soil quality, was to determine the distribution of the total content of cadmium (Cd), nickel (Ni) and arsenic (As). The total content of these elements were observed in composite samples at two depths of 0-10 cm and 0-20 cm and horizons profile. Their total content was measured by atomic AAS. The results were analyzed using Kruskal – Wallis test (p≤0.05) using coefficient χ2. The results showed a single legality of the distribution of Cd, Ni and As in samples of soil profile, while the average soil samples showed unique legality of the distribution of observed elements.

This panel will discuss key aspects of knowledge management (KM) education in response to challenges posed by the necessity to improve KM as a discipline and an established professional field. Through panelists thought-provoking presentations and interactions with the audience, the discussion will address KM education from the starting why, what, who, where and when perspectives to the end result and understanding of how to approach KM education in the future.

Targeted immunotherapy based on PD-1/PD-L1 suppression has revolutionized the treatment of various solid tumors. A remarkable improvement has also been observed in the treatment of patients with refractory/relapsing classical Hodgkin lymphoma (cHL). We investigated PD-L1 status in a variety of treatment resistant lymphomas. Tumor samples from 78 patients with therapy resistant lymphomas were immunohistochemically (IHC) investigated for the expression of PD-L1 using two antibody clones (SP142 and SP263, Ventana). Thirteen PD-L1+ cases were further analyzed for gene copy number variations (CNV) by NGS and for PD-L1/JAK2/PD-L2 co-amplification using fluorescent in-situ hybridization assay (FISH). PD-L1 positivity (≥5% positive cancer cells, IHC) was present in 32/77 (42%) and 33/71 cases (46%) using SP142 and SP263 antibodies, respectively. Concordance between the two anti-PD-L1 clones was high with only three (4%) discrepant cases. The strongest and consistent (10/11 cases) expression was observed in cHL and primary mediastinal B-cell lymphomas (3/3). Diffuse large B-cell lymphomas (DLBCL) were frequently positive (13/26) irrespective of subtype. Follicular (1/8), peripheral T-cell (3/11) and mantle cell (1/8) lymphomas were rarely positive, while small lymphocytic lymphoma/CLL and marginal zone lymphomas were consistently negative (3/3). Co-amplification/CNVs of PD-L1/JAK2/PD-L2 were observed in 3 cases of DLBCL and cHL, respectively. Of note, all three cHL-amplified cases were positive by FISH, but not by NGS. Since only a fraction of the IHC positive lymphoma cases were positive by FISH and NGS assays, other mechanisms are involved in PD-L1 upregulation, especially in DLBCL. FISH assay may be more suitable than NGS assay for determination of PD-L1 alterations in cHL.