Objetivo: Descrever acoes do Conselho Federal de Enfermagem atraves do Comite Gestor de Crise para o Coronavirus no pais. Metodo: descricao de atividades na modalidade de relato de experiencia que teve seus dados coletados nos arquivos, documentos e relatorio do Comite Gestor de Crise em junho de 2020. Resultados: Identificou-se dez macro acoes: criacao do Comite Gestor de Crise, Campanha “Juntos contra o Coronavirus”, Observatorio da Enfermagem, Ouvidoria e Denuncias, Equipamentos de Protecao Individual, Medidas Legais, Apoio em Saude Mental, Capacitacao Profissional e Plantao do Comite de Crise. Consideracoes Finais: as acoes desenvolvidas nesse periodo pelo Cofen contribuiram para aumentar sua interacao com os profissionais de enfermagem, bem como para promover a valorizacao destes perante as agencias de saude governamentais nacionais e internacionais, poder publico e midia nacional e internacional, destacando-se frente a outros conselhos de classe no pais. Descritores: Enfermagem; Infeccoes por Coronavirus; Pratica Profissional. Objective: To describe actions of the Federal Nursing Council through the Crisis Management Committee for Coronavirus in the country. Method: description of activities in the experience report modality that had its data collected in the files, documents and report of the Crisis Management Committee, in June 2020. Results: Ten macro actions were identified: creation of the Crisis Management Committee, “Together against Coronavirus” Campaign, Nursing Observatory, Ombudsman and Complaints, Personal Protective Equipment, Legal Measures, Mental Health Support, Professional Training and on-call the Crisis Committee.  Final Considerations : the actions developed during this period by Federal Nursing Council contributed to increase their interaction with nursing professionals, as well as to promote their valorization before national and international government health agencies, public authorities and national and international media, standing out in front to other class councils in the country. Descriptors: Nursing; Coronavirus Infections; Professional Practice. Objetivo: Describir las acciones del Consejo Federal de Enfermeria a traves del Comite de Manejo de Crisis para el Coronavirus en el pais. Metodo: descripcion de actividades en la modalidad de informe de experiencia que recolecto sus datos en los archivos, documentos e informe del Comite de Gestion de Crisis en junio de 2020. Resultados : Se identificaron diez macro acciones: creacion del Comite de Gestion de Crisis, Campana "Juntos contra el coronavirus", Observatorio de Enfermeria, Defensor del Pueblo y Quejas, Equipo de Proteccion Personal, Medidas Legales, Apoyo a la Salud Mental, Capacitacion Profesional y el Comite de Crisis de guardia. Consideraciones finales: las acciones desarrolladas durante este periodo por Cofen contribuyeron a aumentar su interaccion con los profesionales de enfermeria, asi como a promover su valorizacion ante agencias de salud gubernamentales nacionales e internacionales, autoridades publicas y medios de comunicacion nacionales e internacionales, destacandose a otros consejos de clase en el pais. Descriptores: Enfermeria; Infecciones por Coronavirus; Practica Profesional.

Muesli bars is a generic term that refers to baked or cold-formed cereal-based snack bars, and may contain other ingredients such as fruit, nuts, seeds, chocolate, yoghurt, and a variety of other fillings and/or toppings. By changing the ingredients nutritional value of muesli bar can be modified. In this research, protein-rich and energy-high muesli bars have been produced, because they contain a higher amount of fat, proteins and sugar. However, fats and sugars were not added but come from specific ingredients (hazelnuts, walnuts, chia seeds, sesame, sunflower and pumpkin seeds, oat flakes, etc.). Four muesli bar formulations were developed, two with hazelnuts and two with walnuts, added in the amount of 25% and 50%, respectively. The other ingredients were added in the same amount. The product was dried at 80°C for several hours. The composition, polyphenolic compounds and antioxidant capacity were determined in the products before and after drying. Also, muesli bars were sensory evaluated.

This paper presents the study that would allow a revision of the currently valid diagnostic reference level in intraoral dental X-ray radiography in Bosnia and Herzegovina. The study was conducted for six procedures that are used to capture incisor, premolar and molar teeth, of both maxilla and mandible, in adults. Measurements were performed on 41 intraoral X-ray devices, 20 of which were systems with digital image receptor and 21 film-based X-ray systems. In this study, incident air kerma (Ki) and air kerma-area product (PKA) were used as patient dose descriptors. The third quartile (Q3) of the measured incident air-kerma values was used to compare with the current national diagnostic reference level (DRL) for intraoral dental procedures. The obtained results of Q3 for both types of devices, with film-based and digital image receptors, have shown that the third quartile values are lower (3.5 and 1.2 mGy, respectively) than the current national DRL (7.0 mGy). Hence, new data can be used to re-establish the diagnostic reference levels in intraoral dental X-ray examinations in Bosnia and Herzegovina.

Background Human papillomaviruses (HPVs) and Epstein–Barr virus (EBV), known oncoviruses, can be co-present and cooperate in the initiation and/or progression of human carcinomas, including head and neck. Based on this fact, we recently reported the prevalence of both HPVs and EBV in cervical and breast cancers. Methods We herein explore for the first time the co-prevalence of high-risk HPVs and EBV in 98 head and neck (HN) squamous cell carcinoma (SCC) tissues from Bosnian patients using polymerase chain reaction (PCR) and immunohistochemistry (IHC) analysis, as well as tissue microarray methodology. Results The majority of these cancer tissue cases were from the oral cavity (68%). We found that high-risk HPVs and EBV are co-present in 34.7% of the SCC samples; with a significant correlation between the various HPV types and EBV co-incidence (p = 0.03). Our data showed that 30.8% of oral SCCs are positive for E6 oncoprotein of high-risk HPVs and 44.6% are positive for LMP1 of EBV. The most commonly expressed HPVs in our HNSCC samples include HPV types 16, 18, 45 and 58. Additionally, 37.5% of oral SCCs are positive for both HPVs and EBV, with statistically significant association between high-risk HPV types and EBV (p < 0.05). More importantly, our data revealed that the co-presence of HPV and EBV is strongly correlated with advanced tumor stage (p = 0.035). Conclusion In this study we show that HPV and EBV oncoviruses are co-present in HNSCC, particularly in oral cancer, where they can cooperate in the initiation and/or progression of this cancer. Thus, further studies are necessary to elucidate the mechanism of this cooperation.

Human papillomaviruses (HPVs) and Epstein–Barr virus (EBV), known oncoviruses, can be co-present and cooperate in the initiation and/or progression of human carcinomas, including head and neck. Based on this fact, we recently reported the prevalence of both HPVs and EBV in cervical and breast cancers. We herein explore for the first time the co-prevalence of high-risk HPVs and EBV in 98 head and neck (HN) squamous cell carcinoma (SCC) tissues from Bosnian patients using polymerase chain reaction (PCR) and immunohistochemistry (IHC) analysis, as well as tissue microarray methodology. The majority of these cancer tissue cases were from the oral cavity (68%). We found that high-risk HPVs and EBV are co-present in 34.7% of the SCC samples; with a significant correlation between the various HPV types and EBV co-incidence (p = 0.03). Our data showed that 30.8% of oral SCCs are positive for E6 oncoprotein of high-risk HPVs and 44.6% are positive for LMP1 of EBV. The most commonly expressed HPVs in our HNSCC samples include HPV types 16, 18, 45 and 58. Additionally, 37.5% of oral SCCs are positive for both HPVs and EBV, with statistically significant association between high-risk HPV types and EBV (p < 0.05). More importantly, our data revealed that the co-presence of HPV and EBV is strongly correlated with advanced tumor stage (p = 0.035). In this study we show that HPV and EBV oncoviruses are co-present in HNSCC, particularly in oral cancer, where they can cooperate in the initiation and/or progression of this cancer. Thus, further studies are necessary to elucidate the mechanism of this cooperation.

While the increasing penetration of renewable energy resources into the electric power grid improves energy efficiency and reduces greenhouse gas emissions, it may drive the grid towards weak power grid conditions, under which grid stability issues may affect the operation of inverter-based renewable generators. The short-circuit ratio (SCR) with some modifications has been used to analyze power grid strength. However, the existing SCR-based methods for grid strength assessment neglect the impact of the interactions between shunt capacitors interconnected through the power network, which may cause over-optimistic results of grid strength assessment. To account for the impact, a novel method for grid strength assessment is proposed in this paper by theoretical analysis of how the interconnected capacitors affect static voltage stability. The efficacy of the proposed method is demonstrated through numerical simulation case studies on the IEEE 39-bus system.

The electric power grid is undergoing significant changes in the mix of generation source types. The increasing penetration of renewable energy resources (RERs), such as wind and solar, is improving energy efficiency, but meanwhile it is also challenging grid planners and operators to maintain reliable electricity services. The high penetration of RERs may drive the power grid toward weak grid conditions, which may cause grid stability and reliability issues. One of ways to address these issues is to select appropriate points of interconnection for integrating RERs into power grids. In previous works, grid stability analysis and grid reliability assessment are evaluated separately for selecting the points of interconnection. This paper presents an integrated method for selecting such points by coordinating grid strength assessment and grid reliability evaluation as well as investment cost. The efficacy of the proposed method is demonstrated on the IEEE reliability test system.

The concentrations of 16 polycyclic aromatic hydrocarbons (PAH) in smoked dry sausage Hercegovacka kobasica were investigated. The sausages were stuffed in two different casings (collagen and natural) and smoked in traditional and industrial smokehouses. The highest concentration of PAH 16 were detected in sausages in natural casings smoked in the traditional manner. The samples smoked in the industrial chamber stuffed in collagen casing showed the lowest PAH 16 content. The content of PAH 4 in sausage smoked in the traditional way and stuffed in natural casing averaged 24.46 µg/kg, which is more the double of maximum prescribed concentration of 12 µg/kg. The concentration of cancerogenic benzo[a]pyrene averaged 7.79 µg/kg in sausage stuffed in natural casing and smoked in the traditional way, which is almost four times the legislative prescribed values (2 µg/kg). Sausage smoked in the traditional manner and stuffed in collagen casing showed lower values for PAH 4 (13.88 µg/kg) and benzo[a]pyrene (4.97 µg/kg), but these values were also above the legislative prescribed values.

Human coronaviruses, especially SARS-CoV-2, are emerging pandemic infectious diseases with high morbidity and mortality in certain group of patients. In general, SARS-CoV-2 causes symptoms ranging from the common cold to severe conditions accompanied by lung injury, acute respiratory distress syndrome in addition to other organs’ destruction. The main impact upon SARS-CoV-2 infection is damage to alveolar and acute respiratory failure. Thus, lung cancer patients are identified as a particularly high-risk group for SARS-CoV-2 infection and its complications. On the other hand, it has been reported that SARS-CoV-2 spike (S) protein binds to angiotensin-converting enzyme 2 (ACE-2), that promotes cellular entry of this virus in concert with host proteases, principally transmembrane serine protease 2 (TMPRSS2). Today, there are no vaccines and/or effective drugs against the SARS-CoV-2 coronavirus. Thus, manipulation of key entry genes of this virus especially in lung cancer patients could be one of the best approaches to manage SARS-CoV-2 infection in this group of patients. We herein provide a comprehensive and up-to-date overview of the role of ACE-2 and TMPRSS2 genes, as key entry elements as well as therapeutic targets for SARS-CoV-2 infection, which can help to better understand the applications and capacities of various remedial approaches for infected individuals, especially those with lung cancer.

Abstract In this study, the back calculated compressive properties of flax fibers utilizing the Impregnated Fiber Bundle Test (IFBT) were investigated. The back calculated stress-strain response can be described by the Ramberg-Osgood model. The compressive modulus of the fiber is similar to its tensile modulus. The compressive strength of the fiber is approximately 45 % of its tensile strength. Considering the presence of local fiber kinking within the elementary fibers as well as global fiber kinking due to fiber misalignments and plastic shear deformation in the matrix material, this is a remarkably high value for the compressive strength. Our results indicate that local fiber kinking precedes global fiber kinking. We show that IFBT is a promising method for determining the compressive properties of flax fibers and provides necessary input data for finite element analysis of the compressive failure mechanisms in unidirectional flax fiber reinforced composites.

The coexistence of humans and dogs, in addition to all positive effects, can result in negative effects on human health. A particular risk is posed by a population of stray dogs, that is, dogs without owners and veterinary supervision. A contact with dogs in addition to bites, carries the risk of viral, bacterial and parasitic zoonoses, and can also cause psychological trauma. Children, the elderly and pregnant women are the categories most susceptible to the negative effects of dogs. The aim of the paper was to make an interdisciplinary analysis of the negative effects of dogs on humans. Dog bites cause wounds and dysfunction of damaged tissue, and often lead to various infections. The risks of rabies and tetanus are particularly significant if proper and timely treatment is not performed. Ongoing training for dog owners can significantly reduce the number of bites inflicted by owned dogs, but stray dogs remain a serious social problem and pose potential health risks of some zoonosis. Timely and adequate management of bite wounds and the use of rabies-post-exposure prophylaxis as well as psycho-therapy, where indicated, significantly reduce possible adverse health effects for patients who have been bitten by dogs.

Aim To compare maternal, foetal and neonatal characteristics, and perinatal outcome of preterm and term deliveries in twins pregnancies in order to improve perinatal care in Bosnia and Herzegovina. Methods This retrospective cohort study included pregnant women with twin pregnancy who delivered during the period between 1 January 2012 and 31 December 2018 at the Clinic for Gynaecology and Obstetrics, University Clinical Centre Tuzla. Results During the seven-year period 26 734 deliveries were recorded, out of which 362 (1.35 %) were twin pregnancies, 226 (62.4%) preterm and 136 (37.5%) term ones. In the preterm group 38 (16.8%) pregnancies were assisted medical reproduction, and 16 (11.7%) of those were in the term group. The average birth weight was significantly higher for the first twin in both groups (p<0.00001). Incipient intrauterine foetal asphyxia was more frequent in the preterm group (p<0.05). The most common indication for Caesarean section was abnormalities of foetal presentation and lie, 176 (68.2%) for the overall sample. Conclusion Cornerstone of twin pregnancy antenatal care is to get correct data about amnionicity and chorionicity. Since majority of prenatal data did not have this information we call all obstetricians to declare about amnionicity and chorionicity in twin pregnancies during the first trimester ultrasound examination.

Aim To investigate clinical and obstetrical characteristics, an outcome and a prognosis for pregnant women with diagnosed and treated genital or extragenital cancer and their newborns. Methods This retrospective cohort study included pregnant and childbearing women with a history of cancer diagnosed before pregnancy during the period between 1 January 2014 and 31 December 2018. Data related to the course of pregnancy and childbirth were collected from medical records (mothers' disease history and partogram). The analysis covered clinical and histopathological characteristics of cancers, type of the treatment (surgery, chemotherapy, radiotherapy), demographic data, obstetric characteristics, comorbidities of women, and outcome of the newborns. Results The study recorded 18 414 deliveries, of which 30 (0.16%) were pregnancies in women who had been diagnosed and treated earlier for genital or extragenital cancer. The average age of the women at the time of delivery was 29.43±5.97 years. There were six (20%) women with genital and 24 (80%) with extragenital cancer. The most frequent extra genital cancer was Hodgkin lymphoma, in eight (26.6%) cases; ovarian cancer was the most frequent genital cancer, in four (13.3%) cases. The average time span from the cancer diagnosis and start of the treatment to the delivery was 59.2±44.4 months (5 years) (range 12 months - 15 years). Two (6.6%) women died. Conclusion Our data demonstrate a favourable obstetric and neonatal outcome for women who have survived cancer.