Understanding the impacts of climate on tourism has evolved since the late 20th century, shifting from one-dimensional and partial approaches to more comprehensive and multifaceted ones. To more accurately assess the climatic suitability of destinations for recreational tourism, the Holiday Climate Index (HCI) has been developed in recent years. The HCI's variable rating scale and component weighting system are based on insights into tourists' climatic preferences. Since different types of destinations have distinct climatic requirements, the HCI is designed with specifications for two major tourism segments—urban and beach. The HCI: Urban focuses on urban tourism, where the city and its attractions serve as the primary destination and point of interest. This study analyzes the HCI: Urban for Sarajevo, the most significant tourism destination in Bosnia and Herzegovina. The monthly probability is calculated by determining the frequency of daily index scores within ideal and unacceptable categories. Ideal climatic conditions for urban tourism are defined as days with scores between 90 and 100, while unacceptable conditions are those with scores below 40. Of all tourists visiting Bosnia and Herzegovina in 2023, 41% visited the Sarajevo Canton, which makes it a significant case study. This paper analyzes the HCI: Urban index for Sarajevo in relation to tourist visits throughout the year, and the obtained ratings reflect tourists' climatic preferences for urban destinations. Holiday Climate Index (HCI): Urban was analyzed for the Sarajevo area, the capital of Bosnia and Herzegovina, in order to more accurately assess the climatic suitability of this destination for tourism. The word “holiday” was chosen to better reflect what the index was designed for (i.e. recreational tourism), since tourism is much broader in definition. This paper analyzes the HCI: Urban index for Sarajevo in relation to tourist visits during the year, and the obtained scores reflect tourists' climate preferences for the city destination. Considering that tourists in Sarajevo stay only for a short time (average length of stay 2.1 days), determinants that affect tourist satisfaction and elements of the destination that need to be improved in order to increase the length of stay have been identified. Analysis of average daily values of climatic parameters of a particular destination and monitoring their trend plays an important role in the organization of tourist trips. This research is the first of its kind related to Sarajevo, and understanding local climatic conditions is crucial for developing tourism strategies, planning, and organizing tourism events in the capital of Bosnia and Herzegovina, which is the most visited tourist city in the entire country.

Abstract This article focuses on the allocation of subnational aid from Central European donors and Serbia to Bosnia & Hercegovina between 2005 and 2020. Spatial and statistical analyses revealed different patterns of aid distribution among municipalities in Bosnia & Hercegovina. Two of the seven donors studied—Croatia and Serbia—showed a clear bias in favour of their ethnic minorities in Bosnia & Hercegovina. For other Central European donors there was a general tendency to provide less aid to municipalities with more Croats. The relationship between variables approximating recipients’ needs and Central European aid was weak or insignificant.

This paper analyzes the distribution and size structure of settlements along the primary river courses of Bosnia and Herzegovina, considering both hypsometry and socioeconomic dimensions of space, which contribute to demographic transformations. Using GIS tools, an analysis was conducted on the number of settlements according to hypsometric levels in the river basins of the Black and Adriatic Seas, alongside demographic changes during the latest intercensal period. Spatial analysis methods in GIS enabled the identification of population changes, settlement sizes, and spatial distribution patterns. Analysis of buffer zones within 5 km of river streams reveals a predominant spatial clustering of settlements along these waterways, while a fragmentation of settlement networks is observed farther away from the main streams.

The contemporary demographic development of Bosnia and Herzegovina is a very active topic in academic, but also in wider political and public discourses, particularly in the context of increased depopulation trends. Distinctly negative processes in the natural change and net migration are the result of post-war and transitional circumstances, as well as the socio-economic status of the country. Demographic disparities conditioned by a complex social background (economic, social, political, cultural and environmental factors) are often the subject of geographic research in this area, however, few studies have resulted in a comprehensive demographic categorization of municipalities and cities in Bosnia and Herzegovina, which would be the first step in detection precise causes of demographic regression. Demographic categorization of municipalities on the basis of as many available demographic indicators as possible is a useful instrument in planning, through which concrete revitalization measures can be created primarily aimed at reducing polarization effects in development and depopulation of continuously deprived regions. This study used demographic data from the last 2013 population census, as well as those from more recent publications of national and entity statistical agencies. Special focus is placed on the index of total population change, population density, vital index, ageing coefficient and share of highly educated population. These indicators were analysed from the aspect of regional disparities, whereby special categories of municipalities and cities were created for each of them, in relation to how favourable is local demographic situation. In the second phase, their multi-criteria data integration was carried out, which more clearly indicate the general level of demographic development of individual municipalities/cities.

This paper analyses the statistical parameters that give a comprehensive overview of the socio-demographic state of the border areas of Bosnia and Herzegovina, and it represents a novel attempt to examine the disparity and relationships between central and peripheral parts of national territory. The methodology is based on examining the differences between border and non-border municipalities/cities according to four groups of indicators, to obtain four indices: depopulation, natural change, ageing and education. Statistically significant differences were found primarily in the context of population age structure, and it can be concluded that the ageing process has affected bordering regions more than the rest of the country.

Stabilin-1 is a multifunctional scavenger receptor expressed on alternatively-activated macrophages. Stabilin-1 mediates phagocytosis of “unwanted-self” components, intracellular sorting, and endocytic clearance of extracellular ligands including SPARC that modulates breast cancer growth. The expression of stabilin-1 was found on tumor-associated macrophages (TAM) in mouse and human cancers including melanoma, lymphoma, glioblastoma, and pancreatic insulinoma. Despite its tumor-promoting role in mouse models of melanoma and lymphoma the expression and functional role of stabilin-1 in breast cancer was unknown. Here, we demonstrate that stabilin-1 is expressed on TAM in human breast cancer, and its expression is most pronounced on stage I disease. Using stabilin-1 knockout (ko) mice we show that stabilin-1 facilitates growth of mouse TS/A mammary adenocarcinoma. Endocytosis assay on stabilin-1 ko TAM demonstrated impaired clearance of stabilin-1 ligands including SPARC that was capable of inducing cell death in TS/A cells. Affymetrix microarray analysis on purified TAM and reporter assays in stabilin-1 expressing cell lines demonstrated no influence of stabilin-1 expression on intracellular signalling. Our results suggest stabilin-1 mediated silent clearance of extracellular tumor growth-inhibiting factors (e.g. SPARC) as a mechanism of stabilin-1 induced tumor growth. Silent clearance function of stabilin-1 makes it an attractive candidate for delivery of immunomodulatory anti-cancer therapeutic drugs to TAM.