Milton Friedman’s traditional claim is that flexible exchange rates facilitate external adjustment by means of their cor- rective movements before the balance of payments crisis occurs. In order to test this hypothesis, we employ the first order autoregression based on the panel data on exchange rate regime and external balance expressed as the share of balance of goods and services in GDP. The sample covers 16 Central and Eastern European (CEE) and 12 Common- wealth of Independent States (CIS) transition countries over the period 2000-2019. The results, which are based on the sample of all transition countries, failed to prove that more flexible exchange rate regimes facilitate external adjust- ment. When the analysis was performed on two groups of countries separately, the results showed that the deficit of balance of goods and services in CIS countries has a higher persistence compared to CEE countries. However, a more flexible exchange rate regime does not facilitate external ad- justment. On the other hand, in CEE countries, the relation- ship between exchange rate regime flexibility and the rate of balance of goods and services reversion exists, proving that Friedman’s hypothesis does hold.

Razumijevanje apstraktnih pojmova predstavlja važan izazov za teorijski okvir utemeljene kognicije. Jedna je mogućnost da se apstraktni pojmovi utemeljuju u afektivnim stanjima. U ovome smo radu ispitali hipotezu povezuje li se apstraktni matematički pojam parnosti broja (par – nepar) s pozitivnim i negativnim afektivnim tonom koji je indirektno naznačen predznakom plus i minus. U prvome su eksperimentu ispitanici odgovarali na pitanje je li prezentirani broj paran ili neparan. Kao podražaji prezentirani su cijeli brojevi u rasponu od -9 do 9 bez -5, 0 i 5. Rezultati su pokazali dvosmjernu interakciju između predznaka i parnosti jer su ispitanici bili efikasniji u obradi pozitivnih nego u obradi negativnih parnih brojeva. Također, bili su efikasniji u obradi negativnih nego u obradi pozitivnih neparnih brojeva. U drugome su eksperimentu ispitanici odgovarali na pitanje je li prezentirani broj numerički veći ili manji od 5, pri čemu su trebali ignorirati predznak. Prezentirani su isti podražaji kao i u prvome eksperimentu. Dobivena je složenija trosmjerna interakcija u kojoj su ispitanici bili efikasniji u obradi pozitivnih nego u obradi negativnih parnih brojeva, kao i u prvome eksperimentu, ali taj se efekt pojavio samo za brojeve veće od 5. Rezultati su interpretirani u okviru teorije o korespondenciji polariteta i teorije centralnoga afektivnog utemeljenja.

The failure to engage in responsible behaviour is related to the inability to consider future consequences of actions. An experiment was conducted to examine whetherincreasing the vividness of the future self affects adherence and endorsement of COVID-19 safety measures. A total of 184 participants were randomly assigned to 3 groups. Depending on the experimental condition, they were tasked with writing a letter to other people (their friend), a proximal future self, and a distant future self. Participants in the distant future self and the other people conditions showed greater adherence intentions than proximal future self participants. No differences were found between the distant future self and the other people group. Further group differences were found in the endorsement of safety measures, with the distant-future self-group showing more condemnation than the other two groups. Commitment to the COVID-19 safety measures mediated the group differences on both dependent variables. The results are discussed within the framework of the Construal Level Theory and the Future Self-continuity model.

ABSTRACT The purpose of this study is to examine leadership for learning practices across the world by establishing profiles of leadership at school and country levels. Consequently, the study brings to our attention the (ir)relevance of school and system features for leadership for learning. The paper contributes to the field through the use of an extensive exploratory approach across a varied set of school leadership measures collected from both teachers and principals and contextualized in 42 different educational systems participating in the Teaching and Learning International Survey (TALIS) 2018. Consequently, this work has the potential to generate hypotheses regarding the understanding of the complex nature of school leadership worldwide. Surprisingly, the findings reveal that clusters at the country level primarily do not reflect countries with geographical, linguistic, or political proximity. Such clusters were expected, given the evidence found in the literature that shows leadership to largely be determined by contextual, societal, and cultural values. Nevertheless, the analysis identifies five profiles of leadership across schools, the majority of which can be found in most countries participating in TALIS.

Dear Editor, A 62-year-old female with metastatic melanoma presented with shortness of breath four days after her fourth cycle of combination checkpoint inhibitor therapy (CPI) (nivolumab and ipilimumab) having previously received 12 months of adjuvant nivolumab 14 months earlier. Subsequent investigations confirmed CPI related myocarditis. She also described new onset of symptoms consistent with Raynaud's. Her past medical history included recurrent migraines for which she took propranolol. She was admitted to hospital, and received two 500mg doses of intravenous methylprednisolone, and commenced on a reducing course or oral prednisolone (1mg/kg), lansoprazole and co-trimoxazole prophylaxis. Blood tests initially revealed a negative anti-nuclear antibody, lupus anticoagulant and anticardiolipin antibodies with normal complement levels and rheumatoid factor. However repeat bloods six weeks later revealed a positive ANA and a very mildly positive extractable nuclear antigen (anti-SSA52/Ro autoantibody) by rheumatology did not identify any underlying connective tissue disease and concluded that the Raynaud's was likely to be secondary to the CPI.

Organic food production contributes to the preservation of human health, preservation and protection of the environment and increase of soil fertility, reduction of all forms of pollution as a consequence of intensive agricultural production and animal husbandry. Hence by purchasing products that carry the label organic product consumers indirectly affect the protection and preservation of the environment Organic food is food that is worth investing in due to the smaller amount of harmful substances in the products. Cornel cherry (Cornus mas L.) is one of the most suitable species for organic production. It is adaptable to various abiotic factors and is resistant to numerous pests and diseases. Aims: The aim of the study was to select promising dogwood phenotypes from the natural population for further reproduction by grafting. Study Design: The subject of the research was selected 6 self-growing dogwoods from a rural area. Place and Duration of Study: Samples of fruit were collected at the site of Ćehaje, City of Srebrenik,Tuzla Canton, BiH in the spring of 2019. Methodology: In order to determine the best traits, the measurement of physical quantities, determination of coefficients of variation and analysis of chemical characteristics of dogwood fruits harvested from trees of 6 wild phenotypes marked as DKA1, DKA2, DKA3, DKA4, DKA5 and DKA6 were performed. Results: Based on the analyzed indicators, the DKA6 phenotype showed the best results.

University of Tuzla, Faculty of Natural Sciences and Mathematics, Urfeta Vejzagića 4, 75000 Tuzla, Bosnia and Herzegovina European University ”Kallos”, Maršala Tita 2A-2B, 75000 Tuzla, Bosnia and Herzegovina Institut für Kernphysik, Johannes Gutenberg-Universität Mainz, D-55099 Mainz,Germany P. N. Lebedev Physical Institute, 119991 Moscow, Russia Rudjer Bošković Institute, Bijenička cesta 54, P.O. Box 180, 10002 Zagreb, Croatia Tesla Biotech, Mandlova 7, 10002 Zagreb, Croatia (Dated: July 15, 2021)

An Retraction to this paper has been published: 10.1007/s00198-021-06031-0

Introduction: C-reactive Protein (CRP) as an inflammatory biomarker can be easily determined in saliva, but the values of salivary CRP in periodontitis are not well-studied. The aim of this study was to analyze and determine the values of salivary CRP in non-smokers with periodontitis stage 3 or 4 before and after supragingival and subgingival full-mouth periodontal therapy.Methods: Standard periodontal parameters and saliva samples were collected in 12 non-smoking patients. Patients in the test group (n = 6) underwent supragingival and subgingival full-mouth periodontal therapy, and the control group (n = 6) received only supragingival full-mouth therapy. Both groups received the same oral hygiene instructions in addition to therapy. After 3 months, re-registration of periodontal parameters and re-sampling of saliva for analysis of salivary CRP were done for both groups.Results: Statistical analysis revealed large differences in the values of clinical periodontal parameters and CRP levels in the test group after therapy. Values of salivary CRP in the test and control groups were lower 3 months the therapy; however, the results were not statistically significant. The correlation of clinical periodontal parameters and salivary CRP varied in both groups.Conclusion: Our pilot study reveals decreased concentrations of salivary C-reactive protein in non-smoking patients following non-surgical periodontal therapy. Further studies are needed to prove the reliability of salivary CRP as a biomarker for periodontitis.

Complex construction projects are developed in a dynamic environment, where uncertainty conditions have a great potential to affect project deliverables. In an attempt to efficiently deal with the negative impacts of uncertainty, resilient baseline schedules are produced to improve the probability of reaching project goals, such as respecting the due date and reaching the expected profit. Prior to introducing the resilient scheduling procedure, a taxonomy model was built to account for uncertainty sources in construction projects. Thence, a multi-objective optimization model is presented to manage the impact of uncertainty. This approach can be described as a complex trade-off analysis between three important features of a construction project: duration, stability, and profit. The result of the suggested procedure is presented in a form of a resilient baseline schedule, so the ability of a schedule to absorb uncertain perturbations is improved. The proposed optimization problem is illustrated on the example project network, along which the probabilistic simulation method was used to validate the results of the scheduling process in uncertain conditions. The proposed resilient scheduling approach leads to more accurate forecasting, so the project planning calculations are accepted with increased confidence levels.

Um dos primeiros efeitos da imprensa de caracteres móveis, em Portugal, na segunda metade do século XV, foi a divulgação de obras de piedade popular, tais como os tratados religiosos e de moral prática. Essas obras concentravam diversas prédicas para iniciar os cristãos nos rudimentos da fé católica a partir, sobretudo, dos pecados mortais, dos sentidos do corpo e dos dez mandamentos da lei de Deus. O presente artigo tem como objetivo analisar o peso conferido, especificamente, às boas palavras, igualmente sustentadas sobre a explicitação na forma oral, nomeadamente no momento da confissão auricular e individual, expressos nos manuais impressos da doutrina cristã, de meados do século XV.

Summary Background Congenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally. Many gastrointestinal congenital anomalies are fatal without timely access to neonatal surgical care, but few studies have been done on these conditions in low-income and middle-income countries (LMICs). We compared outcomes of the seven most common gastrointestinal congenital anomalies in low-income, middle-income, and high-income countries globally, and identified factors associated with mortality. Methods We did a multicentre, international prospective cohort study of patients younger than 16 years, presenting to hospital for the first time with oesophageal atresia, congenital diaphragmatic hernia, intestinal atresia, gastroschisis, exomphalos, anorectal malformation, and Hirschsprung's disease. Recruitment was of consecutive patients for a minimum of 1 month between October, 2018, and April, 2019. We collected data on patient demographics, clinical status, interventions, and outcomes using the REDCap platform. Patients were followed up for 30 days after primary intervention, or 30 days after admission if they did not receive an intervention. The primary outcome was all-cause, in-hospital mortality for all conditions combined and each condition individually, stratified by country income status. We did a complete case analysis. Findings We included 3849 patients with 3975 study conditions (560 with oesophageal atresia, 448 with congenital diaphragmatic hernia, 681 with intestinal atresia, 453 with gastroschisis, 325 with exomphalos, 991 with anorectal malformation, and 517 with Hirschsprung's disease) from 264 hospitals (89 in high-income countries, 166 in middle-income countries, and nine in low-income countries) in 74 countries. Of the 3849 patients, 2231 (58·0%) were male. Median gestational age at birth was 38 weeks (IQR 36–39) and median bodyweight at presentation was 2·8 kg (2·3–3·3). Mortality among all patients was 37 (39·8%) of 93 in low-income countries, 583 (20·4%) of 2860 in middle-income countries, and 50 (5·6%) of 896 in high-income countries (p<0·0001 between all country income groups). Gastroschisis had the greatest difference in mortality between country income strata (nine [90·0%] of ten in low-income countries, 97 [31·9%] of 304 in middle-income countries, and two [1·4%] of 139 in high-income countries; p≤0·0001 between all country income groups). Factors significantly associated with higher mortality for all patients combined included country income status (low-income vs high-income countries, risk ratio 2·78 [95% CI 1·88–4·11], p<0·0001; middle-income vs high-income countries, 2·11 [1·59–2·79], p<0·0001), sepsis at presentation (1·20 [1·04–1·40], p=0·016), higher American Society of Anesthesiologists (ASA) score at primary intervention (ASA 4–5 vs ASA 1–2, 1·82 [1·40–2·35], p<0·0001; ASA 3 vs ASA 1–2, 1·58, [1·30–1·92], p<0·0001]), surgical safety checklist not used (1·39 [1·02–1·90], p=0·035), and ventilation or parenteral nutrition unavailable when needed (ventilation 1·96, [1·41–2·71], p=0·0001; parenteral nutrition 1·35, [1·05–1·74], p=0·018). Administration of parenteral nutrition (0·61, [0·47–0·79], p=0·0002) and use of a peripherally inserted central catheter (0·65 [0·50–0·86], p=0·0024) or percutaneous central line (0·69 [0·48–1·00], p=0·049) were associated with lower mortality. Interpretation Unacceptable differences in mortality exist for gastrointestinal congenital anomalies between low-income, middle-income, and high-income countries. Improving access to quality neonatal surgical care in LMICs will be vital to achieve Sustainable Development Goal 3.2 of ending preventable deaths in neonates and children younger than 5 years by 2030. Funding Wellcome Trust.

Our intention is to provide easy methods for estimating entropy and chemical potentials for gas phase reactions. Clausius’ virial theorem set a basis for relating kinetic energy in a body of independent material particles to its potential energy, pointing to their complementary role with respect to the second law of maximum entropy. Based on this partitioning of thermal energy as sensible heat and also as a latent heat or field potential energy, in action mechanics we express the entropy of ideal gases as a capacity factor for enthalpy plus the configurational work to sustain the relative translational, rotational, and vibrational action. This yields algorithms for estimating chemical reaction rates and positions of equilibrium. All properties of state including entropy, work potential as Helmholtz and Gibbs energies, and activated transition state reaction rates can be estimated, using easily accessible molecular properties, such as atomic weights, bond lengths, moments of inertia, and vibrational frequencies. We conclude that the large molecular size of many enzymes may catalyze reaction rates because of their large radial inertia as colloidal particles, maximising action states by impulsive collisions. Understanding how Clausius’ virial theorem justifies partitioning between thermal and statistical properties of entropy, yielding a more complete view of the second law’s evolutionary nature and the principle of maximum entropy. The ease of performing these operations is illustrated with three important chemical gas phase reactions: the reversible dissociation of hydrogen molecules, lysis of water to hydrogen and oxygen, and the reversible formation of ammonia from nitrogen and hydrogen. Employing the ergal also introduced by Clausius to define the reversible internal work overcoming molecular interactions plus the configurational work of change in Gibbs energy, often neglected; this may provide a practical guide for managing industrial processes and risk in climate change at the global scale. The concepts developed should also have value as novel methods for the instruction of senior students.