. Healthcare professionals have a key role to play in the introduction, application and use of technology in clinical practice. The lack of technical expertise and technological understanding poses a challenge to the quality of health services and probably to the safety, dignity and quality of life of patients. Experience so far speaks of computer literacy, which is the basis of the implementation of the health information system and varies according to gender, age and years of work experience. Determine whether computer literacy depends on gender, age, and years of service. The research was conducted according to the type of cross-sectional study, in the population of health workers employed at the Health Center in Jagodina and the General Hospital in Ćuprija. Yesterday’ s sample consisted of 142 respondents. A structured questionnaire was used for data collection, statistical data processing was performed with the computer support of the statistical package for social sciences IBM SPSS Statistics, Version 23 (Statistical Package for Social Sciences). Analysis of variance was used from statistical tests. Results. Sample composed of 78.2% of respondents and 27.2% of respondents; in both groups of respondents, the average achievement on the literacy scale is around 17 points. Age 40 and over is 59%; the first two groups (less than 30 years of age and 30 to 39 years of age) are statistically significantly different from the oldest groups of respondents (F = 4.949, p = 0.003, df = 3). The largest percentage of respondents have a work experience of 10-29 years; younger respondents have more knowledge of computers (F = 7.239, p = 0.000, df = 3). Computer literacy depends on age and years of service.

Background: A significant number of patients who underwent surgical myocardial revascularization (CABG) have various comorbidities, including left ventricular diastolic dysfunction (LVDD). Objective: The aim of this paper is to show that patients with preoperative LVDD are at an increased risk of postoperative adverse events and have a worse prognosis compared to patients without LVDD. Methods: The study included 116 patients who underwent myocardial revascularization (CABG) performed at Medical Institute Bayer in Tuzla over a period of 1 year. None of the patients had previously undergone CABG or valvular surgery, or undergone stent implantation (PCI). The presence of LV diastolic dysfunction was detected by echocardiography, and the patients were divided into two groups: with and without LVDD, and further classified into three degrees of LVDD. Results: Of the total number of subjects who underwent surgical revascularization of the myocardium without echocardiographically detected LVDD, 24.1% were patients, and 75.9% were patients with LVDD. In the group with LVDD, the range of days spent in the intensive care unit (ICU) is significantly higher compared to patients without LVDD. Also, patients with LVDD had a significantly higher number of hours of inotropic support, a significantly higher number of cases of tachycardia, predominantly atrial fibrillation (POAF). In this group of patients, a greater number of other adverse events were observed, such as myocardial infarction, cardiac or renal failure, TIA or CVI. Of the total number of patients in the study, 107 patients survived surgical myocardial revascularization and had a satisfactory recovery while 9 (7.8%) survived, all from the group with LVDD. Conclusion: Patients with preoperative diastolic dysfunction of the left ventricle, especially with III degree of dysfunction, are exposed to a higher postoperative risk of adverse events such as: atrial fibrillation, prolonged stay in the intensive care unit, the need for longer-term support with inotropes, and the fatal outcome was recorded exclusively in patients with LV diastolic dysfunction.

This study was undertaken to determine the effects of humic acid on the growth seedling of two tomato cultivars CeylandoF1 and RallyF1, under greenhouse conditions. Treatment with „Humistar“ was started in the two-leaf stage of the plant. One level of humic acid of 20 ml l-1 was applied to the seedling growing media and each seedling of the species was treated every ten days until transplanting directly into the soil in greenhouse.The higest growth rate: leaf (weight), stem (diameter and weight) and root (weight and lenght) growth were optained in cultivar RallyF1 as compared to the control and leaf, stem and root weight compared to Ceylando F1 cultivar.General, the results showed that humic acid influenced better root development in both examined tomato cultivars.

Cancer-related cognitive dysfunction is an important clinical problem that can interfere with the daily functioning, work productivity, childcare, and other responsibilities of women with a history of breast cancer. Risks of cancer-related cognitive impairment include cancer and cancer treatment, as well as patient-related vulnerabilities. There is no established standard of neuroprotective care or treatment for breast cancer-related cognitive impairment.

Introduction. The human voice is an important characteristic that enables the distinction of human from other living beings. Otherwise, it represents a picture of a person΄s personality, his health, mental and emotional state. The research aims are to determine the voice characteristics of vocal professionals with diagnosed vocal cord nodules by subjective voice assessment and objective voice measurement before and after vocal rehabilitation. Methods. This study has involved 25 examinees, aged 23 to 56. The subjective voice assessment was conducted with the Voice Handicap Index - VHI questionnaire and the objective voice measurement by a computerized laboratory for voice analysis ''Kay Elemetrics''. The obtained data were processed using descriptive and analytical statistics. Results. Before the vocal rehabilitation and the subjective and objective voice measurements, the examinees had greater psychosocial difficulties associated with their voice quality. After two months of vocal rehabilitation, there has been a significant improvement in the voice of all subjects on the VHI scale. A statistically significant and highly statistically significant improvement have been noticed in six out of seven analyzed parameters of vocal A, by the objective measurement of voice. Namely, the obtained values - the percentage of jitter Jitt (%), the percentage of shimmer Shim (%), the relative average perturbation value RAP (%) and the coefficient of fundamental frequency variation - vFo were highly statistically significant (p < 0.01). The VTI - voice turbulence index and the SPI - soft phonation index also improved, the observed difference was statistically significant (p < 0.05), while the observed difference in the FTRI parameter was not statistically significant (p > 0.05). Conclusion. Vocal rehabilitation has influenced the improvement of the voice quality, which means that the results obtained by objective voice measurements were more in accordance with the results of the subjective voice assessment.

Introduction Infective endocarditis is relatively rare in pediatric population, but can result in significant morbidity and mortality. Children with bicuspid aortic valve are at higher risk of developing infective endocarditis as compared to general population. Our objective is to emphasize the importance of rapid diagnosis and proper treatment of infective endocarditis in patients with bicuspid aortic valve with aim to prevent serious adverse events. Case outline We report a case of a 13-year-old girl with newly diagnosed bicuspid aortic valve who developed infective endocarditis with severe complications and underwent cardiac surgery. Recurrent fever and anemia, as well as cardiac murmur were present for six months prior to diagnosing infective endocarditis. During the course of illness, only one of many blood cultures taken was positive for Streptococcus sanguinis. Conclusion Patients with bicuspid aortic valve require careful evaluation for infective endocarditis, especially if recurrent fever associated with anemia is present. Delayed diagnosis of infective endocarditis is associated with serious complications.

Background/Aim: Antibiotic use and resistance represent a growing public health issue, with a specific risk of uncontrolled use of antibiotics in children. The aim of the study was to examine differences in parental knowledge, attitudes and practices about antibiotic use in children between urban and rural areas of the Republic of Srpska. Methods: A cross-sectional study was conducted among 1459 parents of children under 6 years of age, out of which 1201 (82.3 %) lived in urban areas while 258 (17.7 %) lived in rural areas. The research is conducted among parents who brought their children to the selected primary healthcare centres and among parents of children in preschool institutions. Results: The majority of respondents (98.4 %) state that doctors are their main source of information. Only 61.2 % of respondents precisely know which drug is an antibiotic when offered different drugs and respondents from rural areas (54.3 %) more often (p = 0.012) gave more accurate answers when compared to respondents from urban areas (37.3 %). Among parents, 86 % agree with the statement that improper use of antibiotics reduces their effectiveness and leads to bacterial resistance, regardless of groups. More than a half of respondents (52.4 %) do not think that children with flu or common cold symptoms recover faster when they receive antibiotics, significantly more respondents from urban areas (p = 0.001). Respondents from rural areas significantly more often believe that antibiotics can produce harmful effects compared to respondents from urban areas (p = 0.049). Respondents from rural areas significantly more often think that antibiotic use can prevent complications caused by inflammation of the upper respiratory tract (p = 0.006). Parents from rural areas give their children antibiotics without a paediatrician's recommendation significantly more often (4.3 %) compared to respondents from urban areas (0.6 %) (p < 0.001). Conclusion: There are differences in parental knowledge, attitudes and practices regarding antibiotic use and antimicrobial resistance among parents in rural and urban areas. There is need for additional education of parents and for greater engagement of paediatricians in providing guidance and explanations regarding the use of antibiotics.

According to the World Health Organization (WHO) and the International Society for Hypertension, elevated blood pressure is defined as the blood pressure the readings of which consistently range ≥140 mmHg systolic and/or 90 mmHg diastolic. Having in mind the fact that hypertension is one of the leading risk factors for cardiovasluar disease, kidney failure and premature mortality, it is clear that preventive measures should be imposed before the diagnosis is established. The main nutritional measures used in preventing hypertension are: weight loss, Dietary Approaches to Stop Hypertension (DASH diet), reducing salt and alcohol intake and increasing potassium intake. The aim of this paper was to show the preventive effect of the DASH diet on hypertension onset in normotensive patients as well as to highlight that the diet is an integral part of hypertension treatment, in addition to the use of drug therapy for hypertensive patients.

Background: Vaginal microflora plays an important role in cervical carcinogenesis. An increase in vaginal pH is associated with the severity of squamous intraepithelial lesion (SIL) and a decrease in the number of lactobacilli. Microbial dysbiosis contributes to the damage of the epithelial barrier, as well as the reprogramming of immune and metabolic signaling. Dysbiotic bacteria cause damage to the epithelial barrier, immune dysregulation and genotoxicity and create a tumor-permissive microenvironment. Objective: The aim of this study was to determine the presence of risk factors (abnormal colposcopic and microbiological status, elevated pH of the vaginal environment) in regular Pap tests and LSIL. Methods: Retrospective prospective study 2021-2022. 90 women with pap smears were analyzed: 40 with LSIL at the Gynecological Center “Dr. Mahira Jahić” Tuzla and 50 with normal findings at the Tesanj Health Center. General data such as: age of the subjects, reproductive status, contraception, smoking and data on colposcopic examination, microbiological findings and vaginal pH value were analyzed. Statistical data processing was done in the SPSS program. Results: The average age of the test subjects is 39.94, in normal Pap 41.20 years, and in LSIL 38.38 years. The vital characteristics of the subjects did not differ significantly, except for smoking, where in LSIL findings, they consumed cigarettes significantly more often. Abnormal colposcopic examination were found in 85% (N-34) of women with LSIL. In subjects with LSIL, a positive microbiological test for enterobacteria was found in 47.5% (N-19) and a normal pap test in 12% (N-6). Statistically significant difference p=0.00523 p<0.05, E faecalis and E coli had the highest prevalence in LSIL. The mean pH value of the vaginal environment in LSIL is 5.38, and 4.96 in a regular pap test. Subjects with LSIL in 10% (N-4) had a normal pH test, and 48% (N-24) had a normal Pap test. P=0.00129 p < (0.05). A normal pH value was significantly more common in subjects with a normal Pap test. Microbiological flora, especially enterogenic bacteria, are more common in LSIL than in women with a regular pap test. Conclusion: when monitoring women with LSIL, special attention should be paid to the elimination of present enterobacteria (E.faecalis and E.coli) as a possible risk factor in the development of precancerous lesions (SIL) and cervical cancer.

During mechanical activation, qualitative changes that can produce various phenomena occur in the material. In this study, anhydrous sodium carbonate was mechanically activated for 2, 7, 14, and 28 minutes in a vibro mill at a frequency of 3000 oscillations per minute. After activation, four series of activated samples were stored in the air at room conditions for 31 days (relaxation period). To monitor the kinetics of the transformation process of activated sodium carbonate samples, i.e. the mechanism of sodium bicarbonate formation during relaxation, Fourier-transform infrared (FTIR) spectroscopy analysis was used. FTIR testing was performed as a function of relaxation time for all four series of samples, with characteristic groups observed: CO32-, HCO3- and OH-. The obtained results provided kinetics parameters for the transformation of sodium carbonate into sodium bicarbonate due to the chemisorption of moisture and carbon dioxide from the atmosphere.

There have been a significant number of publications about digital workplace transformation. This is due to technological developments in the last decades as well as the COVID-19 pandemic. However, there is no adequate overall definition of the term. This leads to misunderstandings and confused interpretation of the digital workplace, sometimes even narrowing it down to a set of tools or a platform. Given the complexity of digital workplace transformation, there is a need to have an integrated prospective and analyze it not just from a technological perspective, but from an organizational and processes point of view as well. Therefore, this paper is an attempt to review the concept and offer a comprehensive definition of the digital workplace. This includes all the important aspects of the transformation including tools and platforms as well as personal issues, organization, processes and management. The paper provides a systematic literature review of the publications in leading bibliographic and citation bases, starting from Web of Science and Scopus to SpringerLink, IEEE Xplore and Association for Information Systems eLibrary. The review includes not only journal papers, but also leading proceedings, books and other referent publications. It addresses the authors' approaches, perspectives, terminologies, focusses and understanding of workplace transformation over the last decade by a comprehensive review of the state of art of the literature in the field of digital workplace. Finally, a set of recommendations are made to further research in increasingly important subject of digital workplace transformation.

The aim of this study was to compare the yield and fruit quality characteristics of raspberry (Rubus idaeus L.) cultivar ʽMeeker' grown in organic and conventional cultivation systems. The total soluble solids, titratable acidity, ascorbic acid content, total phenolic and flavonoid contents and total antioxidant capacity of raspberry fruits were assessed. The analyses showed that raspberry yields per cane were significantly higher in the conventional cultivation system. In contrast, fruits from organic farming had higher antioxidant levels. The findings of this study indicated that organic farming in the study region increased raspberry quality, but decreased yield, as compared to conventional farming.

The paper presents the distribution of grassland and forest vegetation in the Republika Srpska, zoning by natural regions and altitude zones and the changes that occurred in the period 2000-2018. The territory of Republika Srpska belongs to three large natural regions of different physical and geographical characteristics, with specific environmental factors that affect the distribution of vegetation. Altitude significantly affects the occurrence and types of vegetation, so a digital elevation model with a 25 m resolution was used for the analysis of vertical zonality, in order to process data on the distribution of grasslands and forests by altitude zones. Copernicus Grassland and Forest databases were used, for the period 2012-2018. Given climate change and increasing droughts, which indirectly affect the quantity and quality of vegetation, monitoring and managing grasslands and forests will be an important challenge for Republika Srpska. The results of the research show that the grassland according to the Copernicus Grassland database occupies 19.7%, and the forest vegetation according to the Copernicus Forest covers 60.1%, which is almost 80% of the territory of Republika Srpska. Grasslands are most widespread in the area of medium-high and high karst fields of eastern Herzegovina. There are more pastures in the lower altitude zones, while natural grasslands predominate in the higher zones. Forests predominate in the central mountain-valley region. Broad-leaved forests dominate at lower altitudes and coniferous forests at higher altitudes. The European program for monitoring the Earth's surface via satellite remote sensing is a new technology, so the results obtained for the territory of Republika Srpska can be considered a novelty, which is the most significant contribution of this paper.