Objectives: To measure and analyze the seroprevalence and risk factors of human brucellosis among clinically suspected patients in the Travnik area, Bosnia and Herzegovina in the period 2018-2023. Methods: A total of 337 samples of clinically suspected brucellosis patients in Travnik, Central Bosnia and Herzegovina were collected between 2018-2023. Rose Bengal agglutination was used for sera testing. Expressive and investigative statistics were considered. Differences between the prevalence of brucellosis according to age, sex, and the seasonal incidence rate were assessed. Results: The prevalence of brucellosis among the suspected patients was 23.30%. The highest prevalence rate 35.71%, was detected during year 2021. Higher rate of brucellosis was observed among males 63.86% than females 36.14%. Most cases were reported during month of June and October, 14.15% and 14.19% respectively. The highest prevalence, 56.76% rate was observed in age group 41–60 years old. Conclusion: Our survey found a high prevalence of human brucellosis among clinically suspected patients in Travnik area strongly indicating that clinical suspicion is a valid criterion, which requires fast laboratory detection and patient treatment. Detecting specific anti-Brucella antibodies using agglutination Rose Bengal test is a fast a reliable diagnostic procedure for clinically suspect individuals. There is a strong association between human brucellosis and age.

Dried apples improve your health owing to their mineral contents. The main function of packaging dried apples is to protect the packaged product from external factors that may affect the contents' physicochemical, mechanical, and sensory changes during the storage period. The study investigates the sensory characteristics and content of hydroxymethyl-furfural and polyphenols in dried apples and health-related considerations. To gratify that aim, the mixed apple sample was calibrated (precise sorting according to the size and color of the apples), selected, washed, and cut into slices. The product is sulfurized with SO2, the procedure takes several hours, and it is immediately introduced into the dryer. The mass is dried in a dryer "Iverak" (Valjevo, Serbia) with warm air at a temperature of max 65 ° C for 15-18 hours. Packaging materials used in the study are: 1. Monomaterial, polyethylene (PE), thickness 95μ m (PE (95) μ m); 2. Combined packaging material, oriented polypropylene metallized (OPP), thickness 20 μ m (OPPmet (20) μ m); 3.Combined packaging material, oriented polypropylene (OPP) / polyethylene (PE) thickness 20 / 50μ m (OPP / PE (20/50) μ m); 4.Combined packaging material, oriented polypropylene metallized (OPPmet) / polyethylene (PE) thickness 20 / 50μ m (OPPmet / PE (20/50) μ m); 5.Combined packaging materials, polyester (PET) / oriented polypropylene metallized (OPP) met / polyethylene thickness 12/38/30 (PET/OPPmet/PE(12/38/30) μ m). The study presents the results of testing in changes of content of hydroxymethyl-furfural (HMF), polyphenols and sensory properties, dried apples packed in different combinations of packaging materials, including PE (95) μ m, OPP met (20) μ m, OPP / PE (20/50) μ m, OPP met / PE (20/50) μ m, PET / OPP met / PE (12/38/30 μ m), considering health issues. The article's findings can make a notable contribution to the knowledge of the thermal kinetics of antioxidant impacts and phenolic content over the production of apple chips.

Sensory integration is the organization of the senses for their use. It is a neuro-biological activity that allows the reception and processing of sensory information, which in large quantities from the senses come to the brain, at all times. The aim of the study is to examine the prevalence of sensory integration difficulties of the tactile sensory system of children with developmental disabilities, and to establish the statistical significance of differences in relation to the type of difficulty. The total sample of respondents (N=60) consisted of four subsamples of 15 respondents, namely; children with autism, children with Down syndrome, children with hearing impairment and children with sight impairment. The Mann-Whitney U test and the Wilcoxon W test at the level of statistical significance of p<0.05 were used to test the statistical significance of the differences between the subsamples of the subjects. The results of the study show that 86.67% of children with autism, 66.67% of children with Down syndrome, 20% of children with hearing impairment and 40% of children with sight impairment have difficulties with sensory integration of the tactile system. Children with hearing impairment (Rank M 43.97), children with sight impairment (Rank M 35.03), children with Down syndrome, and children with autism (Rank M 14.93) show the least difficulty in sensory integration of the tactile sensory system. There is a statistically significant difference in the difficulties of sensory integration of the tactile sensory system between children with autism, children with Down syndrome, children with hearing impairment and children with sight impairment at the level of statistical significance of p<0.05.