Introduction: We are increasingly witnessing the self-initiated, uncontrolled stacking of incompatible anabolic substances in various cycles in the young Balkan Recreational Bodybuilding population group, increasingly frequent acts of violence in our country and the emergence of a neglected and very silent epidemic that is taking on an increasingly aggressive course of illness and psychological behavior. Black market anabolic steroids are associated with many generally health problems and uncontrolled aggression behavior by abusers. Young unsolicited recreate bodybuilding are also associated with generalized atherosclerosis and potential increased high risk for heart disease that can structural and functional damage the cardiovascular system during muscle mass steroid cycles. Besides high calorie intake, elevating serum blood lipid cholesterol levels LDL lowering HDL levels, elevating, systolic and diastolic blood pressure take a certain participation in cardiovascular risk and therefor need a development of certain cardiovascular protection strategies for this avoiding medical supervision anabolic steroids abuser group which are not yet appropriate established. The aim of the short study was to estimate Cardiovascular Protective Strategy Measures on lipid levels, and blood pressure status in a young recreational bodybuilder with different ethnic groups who Abuse Anabolic Steroids during controversial and different mass Cycles with and without taking Polyunsaturated Fatty Acids and Acetylsalicylic Acid (ASA) and Statins. Subjects and methods: This study was conducted from beginning of January, 2022 till end of July, 2022. 140 subjects are included age 17-30 (74 male Recreational Bodybuilder Who Abuse Anabolic Steroids on Simvastatin’s 10mg and Acetylsalicylic Acid 150mg doses of (ASA) and 10 grams of Polyunsaturated Fatty Acids during mass Steroid Cycles and 66 impellers group of male Recreational Bodybuilder Who Abuse Anabolic Steroids consisting without consume Statins and Acetylsalicylic Acid (ASA) during mass Steroid Cycles). For the testing of statistical significance of differences between the exanimated groups non-parameter and parameter tests were used. The difference at a level of p< (0,001) was statistically significant. Results: In all the tested subjects we investigated increasing lipid levels and blood pressure after six months of study. Analysis shows the statistically insignificant influence of antiplatelet therapy (150mg Acetylsalicylic acid) (ASA), combined with Simvastatin 10mg p<(0,001) in steroid abuse subjects during irrational muscle mass steroid cycles. Conclusion: Lack of familiarity with combinations of anabolic substances, as well as the danger of oral applications of very harmful steroids from the former Soviet Union and German Democratic Republic (GDR), this study showed. Avoidance of physician supervision by recreate bodybuilders by deceiving of the athletic subjectivity look, seams appears almost always in gym. This cardiovascular protective measures have poor benefit appeared to be usefully blind preventing strategy of controlling blood lipid levels during muscle mass steroid cycles, with no guaranty of worsen cardiovascular condition by abusing anabolic steroids. The influence of the reflection of the COVID 19 virus on such dramatic therapeutic results in this population group of two groups cannot be ruled out for sure.

Introduction: Adequate individual physical activity after COVID 19 infection as a inevitable part of postoperative therapy of surgically treated vascular and endovascular patients witch still remains a scientific unexplored international neglected secret. General post-covid symptomatology is increasingly present in patients with surgical or endovascular procedures on the iliac segment in the form of a manifestation of various complaints that can affect the very accessibility of the choice of treatment according to the TASC II guidelines, but also affect physical activity and quality of life. Besides the medicament treatment, the management of moderate intensity exercise therapy and future consistency of self-controlled exercise after surgical and endovascular after treatment in iliac critic stenosis with other asymptomatic systemic atherosclerosis can be important factor to support and improve benefits of surgical and endovascular treatment outcome in variable symptomatology of POSTCOVID 19 patients treated classical surgical and endovascular. Goals: The focus is on priority of investigation of remodeling the pattern of cultural smoking behavior and increasing the dynamic of physical activity trying to prevent and avoid potential risk of sudden death, myocardial infarction, stroke graft (stent) occlusion, and cardiovascular mortality in patients with POSTCOVID 19 symptomatology in which is besides other asymptomatic systemic atherosclerosis is the main disease critical iliac artery stenosis (TASC II A and B). Scientifically unproven that sometimes can be associated with poor outcome of surgical intervention the which are in deficit with scientific studies to confirm these scientific observations. Second goals are to investigate the potential possibility of POST COVID 19 symptomatology associated with the success of classic surgical bypass or endovascular intervention and the possibility of reflection on physical activity after vascular intervention. Also the improving and secure the quality of life after successful surgical bypass and endovascular revascularization treatment with influence on primary iliac (TASC II A and B) vascular intervention potency one of main goals as well suppress permanent or permanent consequences of the Covid 19 virus during therapeutic surgical or endovascular procedures of the iliac segment (TASC II A and B) Traditional food as well wrong choice of diet and continuous fight with nicotinism is still remains generally main health threat. Subjects and Methods: 266 Symptomatic post COVID 19 Patients with were observed during 3 years (134 patients with surgical dacron reconstruction and 132 with endovascular treatmant of short segment critical iliac artery stenosis) Moderate interval Intensity Training with Short Interval Repetitions on standard treadmill procedure. Results: The connection of the outcome of surgical and endovascular treatment with post and long covid 19 symptomatology is possible and has a significant impact on the quality of the continuation of physical medication therapy. Difference between the surgical and endovascular groups was observed after the implementation of the treatment as well as factors affecting the outcome of therapy. the outcome is devastating with the prevention of the risk factor of nicotism as well as with the lack of physical activity in some groups. Conclusion: Primary potency after Three years of Endovascular procedure and Dacron bypass Revascularization, has shown as successful with support of supervised exercise training in POSTCOVID 19 patients. Nicotiism still remains highly potency outcome threat when supporting exercise therapy. Also, future and recent studies on this topic should expand their understanding of the effect of the COVID 19 virus on the body in this patients, as well as improving the quality of life in order to improve the patency of bypass or endovascular intervention on the arterial iliac segment.

Introduction: Doping which includes veterinary drugs as irrational human medicine after the infection with COVID 19 still leaves the field open from the aspect of vascular surgery and angiology of the iliac segment. Reflection of the effect of the COVID 19 virus on the sports performance of athletes in various sports after the corona virus is still present. Some athletes have had a hard time individually coping with the clinical consequences after a long illness of the COVID 19 virus. Even though covert doping is part of the everyday life of an elite athlete, it still remains an unresolved topic in the form of a solution for post-COVID 19 symptoms or switching to or taking some other masked substances that are impossible to detect in the blood, as well as a potential reflection on the morphological changes of the arteries. Although consequences of the corona virus for the cardiorespiratory system have been reported, a question arises as to the connection between the development of iliac syndrome and pathomorphological arterial iliac changes in athletes with suspicion of potential correlation with underground doping substances of pharmacologically untested origin in the Balkan population. Widespread global COVID 19 pandemic and the isolation factor have forced numerous athletes to switch their normal training routine and protocols to alternatives such as cycling with or without abusing illegal substance. Increased intima-media thickness, the first structural change detected in atherosclerosis, is an important surrogate marker in atherosclerosis can be connected with high intensity endurance cyclists, running and triathlon competitive athletes affecting their poor performance status and professional doping levels. In some cases, amateur and recreational athletes are also affected especially if they were exposed to COVID 19 infection and doping. Goals: The primary focus of the present study is to determine the initial progression of the disease during and after the COVID 19 pandemic, starting from morphological changes and obstructive arteriopathy of the external iliac artery on account of measuring intima media thickness and the possibility of outset of kinking and obstructive arterial disease of the external iliac artery after 3 years. The secondary focus of the study is to examine the influence of doping on the pathomorphological changes of the external iliac artery during 3 years of research. Subjects and Methods: two groups of were observed (recreational and amateur cyclist). In total 63 selected subjects in the demographic area of ​​former Yugoslavia without cardiovascular disease were observed during the January 2021 and January 2024 period (3 years). Results: Changes in intima-media thickness of iliac artery from baseline 3 years were observed between the standard exercise amateur group and recreational control group. However, intensity exercise under 9000km per year were no significant developing progression of intima-media thickness of iliac artery during 3 years in recreational control group, but minimal progression of intima-media thickness of iliac artery were significant in amateur cycling group due to the potential effect of doping. Conclusion: The application of doping itself is indisputable, but the missing link that would confirm this claim is scientifically limited. We cannot confirm with certainty what is the trigger for the progression of pathomorphological changes and whether the consequences of overcoming the COVID 19 infection or doping. But there are many scientific facts and studies that confirm the connection between progressive atherosclerosis and illegal underground doping substances of pharmacologically untested origin. The consequences may result with a tendency for a futuristic vascular invasive patch or bypass surgical treatment.

Serum levels of testosterone (ST) and high-density lipoprotein (HDL) are generally associated with atherosclerosis in male patients over 50 years with critic iliac stenosis (TASC II A and B) and cardiovascular disease with significant changes in HDL and low-density lipoprotein (LDL). In addition to the standard therapy, combined medicamentous therapy and adequate model of exercise are also important factors as medicines can improve HDL levels and primary bypass and endovascular potency impacting positively on improvement of ST or it can be the following testosterone replacement therapy (TRT) comprising cardiovascular disease prevention and vascular treatment as adjunct therapy options after endovascular and vascular surgical procedures. The aim of the study is to identify the association between HDL and ST after surgical and endovascular intervention on the iliac segment (TASCII A and B), as well as cardiovascular risk factors with modified medium activity (MET) <6 with short interval increase over >6 (MET), with total duration of 30–60 minutes. It also attempts to remodel a patient behavioral pattern, optimize ST levels and link them to outcomes and patency of vascular procedures on the iliac segment. Materials and methods. 108 selected male patients with cardiovascular disease combined with metabolic syndrome and critical iliac artery stenosis (TASC II A and B) were examined during 2014–2018, 4 years after invasive and minimal invasive treatment (54 patients were treated with surgical Dacron reconstruction and 54 patients – with endovascular treatment on short segment of critical iliac artery stenosis (TASC II A and B). Results. In the total population, no difference was observed in changes of constraint-induced movement therapy between the standard exercise group and the control one after 4 years from baseline. However, there was no significant interaction between the effect of exercise trainings and primary bypass potency within 4 years. Conclusions. Primary effects of endovascular procedure and Dacron bypass revascularization raise the risk of elevated testosterone levels after 4 years of group training but does not provide adequate answers to questions as to whether higher levels of ST have any major influence on primary bypass potency preventing further progression of cardiovascular disease and general symptomatic and asymptomatic atherosclerosis. However, exercise and TRT can be potential adjunctive therapeutic options for a future supporting postsurgical and endovascular illiac treatment in cardiovascular patients with low testosterone levels.

Introduction: Knowledge leakage about potential Testosterone side effects on mental and physical condition is present in many young recreational bodybuilders in Bosnia and Herzegovina between 18 and 25 years of age, who have no motivation to compete and who suffer from the Muscle dysmorphia Adonis Complex. Risk factors such as aggression behaviour, acne vulgaris, gynecomastia, arterial hypertension and increasing lipid levels represent major side effects. Some risk factors such as arterial hypertension and increased lipid levels play important role in the pathogenicity of Testosterone when combined with Mass Supplements. These risk factors are responsible for the occurrence of permanent cardiovascular damage in young recreational bodybuilders. Objective: The aim of the study was to estimate the side effects of abusing testosterone in young recreational bodybuilders who have no motivation to compete. This Study will try to estimate and analyse the influence of testosterone side effects on vascular status HDL/LDL (High-density lipoprotein/Low-density lipoprotein serum lipid) levels, aggression behaviour, presence of acne vulgaris, gynecomastia, and arterial hypertension in young recreational bodybuilders aged between 18 and 25 in Bosnia and Herzegovina after a 2 year research. Methods: The prospective study included 100 individuals included in the recreational exercising programme in the period between July 2014 and July 2016. 50 individuals abusing testosterone during the 2 year period were compared with 50 individuals who were not abusing testosterone. Non-invasive methods were used in all individuals (clinical examination and laboratory tests of lipid levels). The routine of anaerobic weight training units in the Gym for both groups was 1,5 – 3,5 hours, 4-6 times per week. Results: Final analysis has revealed that statistically dominant population of young testosterone drug abusers are males (100%) or 50 individuals. Analysis has revealed that the testosterone abuse group have increased levels of LDL lipid serum when compared with the other group and it is the most dominant side effect. HDL (High-density lipoprotein) levels under 1,03 mmol/L were more present in Testosterone abuser group in 45 individuals or (93,3%) and was statistically considered significant (p<0,05). Conclusions: Recreational male bodybuilders between 18 and 25 years of age are dominant testosterone abusers, trying to achieve better muscle proportion and physical performance neglecting the testosterone side effects. We could not prove health benefits from increased serum and for young recreational bodybuilders one of the serious health consequence of using testosterone during recreational exercising programme were the devastating LDL lipid levels which is also connected with the development of arterial hypertension and hyperlipidaemia progressing the pathogenicity of cardiovascular disease followed by devastating health disorders. The benefits of anaerobic weight training for those who abused testosterone in regards to their cardiovascular safety have not been confirmed.