Exercise training markedly improves walking ability in patients with peripheral artery disease and intermittent claudication. However, the effectiveness of these programs is poorly described when co-administered along with conventional pharmacological therapy. PURPOSE: To compare responses in selected hemodynamic outcomes among patient suffering from peripheral artery diseases of lower limbs assigned to medication therapy (MT), and medication therapy and prescribed exercise (MTPE). METHODS: Sixty-four male patients participated in this study, with participants separated into MT group (n=33) and MTPE group (n=31). Exercise program included 3-5 sessions per week lasting for 30 to 50 min, during 4-month period. The claudication distance and peak systolic velocity (PSV) were measured for both groups at beginning and at the end of the study. RESULTS: At follow up, both PSV and claudication distance improved in MT and MTPE as compared to the baseline (p < 0.05), with the degree of improvement or claudication distance was higher in MTPE group (97.5 vs 61.72%; p < 0.01). CONCLUSION: Prescribed exercise program improved clinician-reported outcomes in men with peripheral artery disease when co-administered with pharmacological therapy.

Aims: Determine health effects of programmed physical activities on blood fats in peripheral arterial disease of lower limbs or in examinees on medication therapy and examinees performing programmed physical activities along with the medication therapy. Methods: Overall research has been carried out at the Clinic for Vascular Disease CCUS. Before involvement into the study, examinees had to meet the inclusion criteria. Research was carried out as randomized controlled trial including 100 patients with arterial disease of lower limbs, who meet inclusion criteria: control group (CG, n=50) and test group (TG, n=50). Total level of cholesterol was used for effects assessment of 28 weeks of applied programmed activity in patients. Results: Values of total cholesterol (tCh) and triglycerides before and after treatment in patients of CG and TG showed statistically significant change of its mean values. Significant decrease were marked in tCh and triglycerides levels in TG compared to CG. Conclusion: Adequate programmed physical activities in patients with peripheral vascular disease appeared as very successful in treated patients. Results indicate statistically significant decrease of the cholesterol and triglycerides after the treatment. Physical activity used in the treatment made partial regression of arterial diseases and saved patients for undergoing to surgery. Lower level of total cholesterol represents a ten year period prevention of initial stage in progress of arterial diseases.

Goal: The goal of the article is to examine level of hemodynamic improvement in the peripheral artery diseases of lower limbs among patients on medication therapy and patients included in programmed physical activities simultaneously with the medication therapy. Material and methods: Prospective-retrospective study includes 100 patients of the Clinic for Vascular Disease, Clinical Center of Sarjevo University (CCUS). It has been found out that the majority of patients in both groups were males. Average age of patients in control group was 48.60±3.82. Average value of claudication distance for patients in control group was 277 m, while the value for patients in test group was 270 m. Results: At the end of research the analysis of average PSV values proved significant difference in relation to examined groups (p<0.05). Average PSV value statistically significantly decreased in both groups after the treatment. According to the obtained results it was determined that the claudication distance of control group was statistically considerably smaller in comparison to the average claudication distance in the test group. Conclusion: It was established that the chance for the patients to have claudication distance within reference values is 2.57 times higher in the test group in comparison with the patients in the control group after the treatment.