The Effeciveness of Exercise Prescription in Patients Treated for Peripheral Artery Disease of Lower Limbs: 297 Board #134 June 1, 11: 00 AM - 12: 30 PM.
Exercise training markedly improves walking ability in patients with peripheral artery disease and intermittent claudication. However, the effectiveness of these programs is poorly described when co-administered along with conventional pharmacological therapy. PURPOSE: To compare responses in selected hemodynamic outcomes among patient suffering from peripheral artery diseases of lower limbs assigned to medication therapy (MT), and medication therapy and prescribed exercise (MTPE). METHODS: Sixty-four male patients participated in this study, with participants separated into MT group (n=33) and MTPE group (n=31). Exercise program included 3-5 sessions per week lasting for 30 to 50 min, during 4-month period. The claudication distance and peak systolic velocity (PSV) were measured for both groups at beginning and at the end of the study. RESULTS: At follow up, both PSV and claudication distance improved in MT and MTPE as compared to the baseline (p < 0.05), with the degree of improvement or claudication distance was higher in MTPE group (97.5 vs 61.72%; p < 0.01). CONCLUSION: Prescribed exercise program improved clinician-reported outcomes in men with peripheral artery disease when co-administered with pharmacological therapy.