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Publikacije (28)

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Z. Ercegović, Mirza Moranjkić, Mirsad Hodžić, Dželil Korkut, Selma Jakupović, M. Zornić, H. Brkić

Background: Recognition that total laminectomy may perpetuate or cause segmental instability heralded the introduction of less invasive techniques of decompression in lumbar spinal stenosis surgery. Aim : It was our aim to compare formal laminectomy and minimally invasive decompressive procedures in terms of safety and clinical outcome, specifically in respect to the development of postoperative spinal instability. Methods: A retrospective analysis of medical records for 73 patients operated on for lumbar spinal stenosis (22 patients after laminectomy and 51 patients after minimally invasive decompression), with available follow-up data was performed. Basic variables were analyzed in respect to clinical outcome and in regard to development of radiological instability. Results: Radiologic instability was present in 27,3% of patients after laminectomy, as compared to only 2,0% after laminotomy (p<0,001). Regression analysis identified presence of preoperative slip (p=0,0056) and type of surgery (p=0,0204) as sole predictors of instability after surgery. Clinical outcome analysis (laminectomy vs. laminotomy) revealed favorable outcome in both treatment groups, although significantly in favor of the laminotomy group (VAS p= 0,013 and RM p=0,031). Finally, difference in outcome was affected by weather radiologic instability was present or not (p=0,04 and p=0,09 for difference in outcome graded by VAS and RM values respectively) Conclusion: Our results suggest that laminectomy is associated with prohibitively high incidence of postoperative radiologic instability when compared to minimally invasive decompression techniques. Furthermore, radiological instability translates to worse clinical outcome. Finally, patients undergoing laminectomy experience less favorable clinical outcome when compared to those undergoing minimally invasive decompression surgeries.

M. Zornić, Selma Jakupović, F. Roux

Objective – This research was undertaken to analyse the clinical characteristics, treatment methods, complications and outcome in paediatric patients with medulloblastomas.  Patients and method – The study comprised a retrospective analysis of 13 consecutive patients younger than 15 years, who were hospitalized for surgical treatment of medulloblastomas. The clinical characteristics, radiology findings on the initial and control CT or NMR images, the localization and size of the tumour, the type of resection, the method of treatment of hydrocephalus, complications and outcome of treatment were analysed.  Results – There were 13 (26%) children with medulloblastomas in the total number analysed of tumours of the posterior fossa. The average age of the patients was 103±45 months. The average size of the medulloblastoma was 39 mm. The most common symptoms and signs were related to increased intracranial hypertension.  Conclusion – The best form of treatment of medulloblastomas is maximum surgical resection with the appropriate use of radiotherapy and/or chemotherapy depending on the age of the child.

M. Zornić, Dželil Korkut, Selma Jakupović, F. Roux

Objective – The aim of the study was to analyse the clinico-pathological characteristics, treatment, complications and outcome in paediatric patients with infratentorial ependymomas.  Patients and Methods – A retrospective analysis of 6 patients younger than 15 years and hospitalized for surgical treatment of infratentorial ependymomas was performed. The intracranial hypertension, neurological status, radiological CT or MRI findings, tumours localization, type of resection, hydrocephalus treatment, histopathology, complications and outcome were analysed.  Results – There were 6 (12%) of children with infratentorial ependymomas among the posteror cranial fossa tumours. The average age of the patients was 48±55 months. The average size of ependymomas was 42 mm. The most common neurological signs and symptoms before diagnostic procedures were high intracranial pressure and ataxia.  Conclusion  – The best treatment option for infratentorial ependymomas is surgery with a complete resection whenever possible, followed by radiotherapy and/or chemotherapy taking into consideration the age of the patients and histological characteristics of the tumours.

Dželil Korkut, Mirza Moranjkić, Z. Ercegović, Mirsad Hodžić, Munevera Hadžimešić, Selma Jakupović

Trigonocephaly denotes the calvarial deformity caused by premature closure of the metopic suture (metopic synostosis). The frequency of craniosynostosis in general is estimated to be 0.4 per 1000 live births, and trigonocephaly accounts for 5% of all craniostenoses, meaning that this condition is fairly rare. Several studies disclosed that craniosynostosis in twins is a very rare occurrence among craniofacial anomalies. We present a rare case of trigonocephaly in twins where surgery yielded cosmetically satisfactory results.

Throughout the history of the dentistry, dental amalgam represents the most often used restorative material. However, the fact that one of its main components is mercury is the cause of the intensive discussions about the safety of these restorative materials and during the last 150 years polarizes the professional and scientific circles. Proamalgamists consider amalgam safe and useful material, but antiamalgamists mark it as cause of the whole spectrum of diseases. The wish of the authors was that, through the presentation of the literature published from the nineties of the last century to date, present the review of this very issue, which still causes the dilemma in the modern dentistry.

A non-carious cervical lesion ( NCCL) is defined as loss of dental hard tissue in the cervical part of the tooth, not caused by caries, multicausal and insufficiently clarified etiology. Identification of specific etiological factors NCCL is a key in making decisions about treatment. The authors conducted a study to evaluate the prevalence and distribution of noncarious cervical lesions in adults. Material and Methods: The sample of 210 respondents, were divided into three age groups. Clinical inspection has determined the distribution of NCCL within the respondents in relation to their age, teeth groups, vestibular and oral surfaces of the teeth, sides of the jaws and expression of NCCL according to the tooth wear Smith– Knight Index. Results: This research points to a very common finding NCCL within our respondents. Cervical lesions were diagnosed in 78.6% respondents in the first, 91.4% in the second and 97.2% in the third group. It has been shown that the number and expression of cervical lesions increases with age of respondents. Noncarious cervical lesions are usually the most visible on premolars, furthermore the first molars and canines, the second molars and then incisors. The minimum number of lesions were diagnosed in the third molars. Conclusion: Given the high prevalence of NCCL’s, there are reasonable grounds for introducing the tooth wear Index to the wider clinical practice, recording noncarious cervical lesions in dental records, creating specific prevention strategies and effective treatments.

Mirsad Hodžić, Hasan Altumbabić, Mirza Moranjkić, Z. Ercegović, Selma Jakupović

Objective – The aim of this study was to present our experience in managed neural tube defect in a consecutive series of 18 patients.  Material and methods – In the period between October 2003 and October 2007 eighteen patients with neural tube defect (NTD) were operated at Department of neurosurgery of University clinical center Tuzla. Each patient with suspected NTD was evaluated by pediatricians, radiologists and neurosurgeons with clinical findings and ultrasound investigation, computerized tomography and/or magnetic resonance imaging scans of the spine and head.  Results  – The neurosurgical data of 18 patients with NTD who were admitted and treated at our department over the four year period were studied retrospectively. The average age at the time of presentation was 15.7 months, ranging from 1 day to 8 years. Spinal NTD was noticed in 13 (72.2%) patients and cranial in 5 (27.8%) patients. Surgery was performed on emergency basis immediately upon birth for CSF leakage in five patients (38,5%) with spinal dysraphism. No postoperative cerebrospinal fluid leakage was noticed and there was no mortality.  Conclusion  – Patients born with neural tube defect need an interdisciplinary team of specialists to oversee their developmental progress. Once born, a child with NTD must be operated in order to avoid fluid infection.

H. Brkić, P. Kehrly, Selma Jakupović, M. Zornić

OBJECTIVE Intraparenchimal mesencephalic cyst which occurs in lateral part of the mesencephalon is very unusual. In addition to describe this case, the authors also review other brainstem cysts described in literature and briefly discus concept of their origin. METHODS We report a patients with cyst in right part of the mesencephalon of a 10-years old girl presenting symptoms of increased intracranial pressure and local compression. We discuss the clinical presentation, radiological investignation, pathological features and surgical treatment options for this lesion. DISCUSSION First surgical intervention was fenestration cysts, second ventricular-peritoneal shunt and third stereotactic navigation cysto-cysternostomo mesencephalic cyst with ponotocerebelar subarachnoidal space. Biochemical examination showed fluid in cyst and patohistological examination showed fibrilar connective tissue without epithelial cell of the wall cysts. CONCLUSION Eight years later she is in good condition. Surgical resection or total extirpation cyst like that is not recommended.

H. Brkić, Selma Jakupović, M. Zornić

INTRODUCTION In this study was analyzed 49 persons with lumbar lateral recess stenosis who were treated by operation. Resection articular facets was main principe for decompression root of nerve in lateral recess region. After operation we noticed sings of recovory during next sixth mounts. Many study were wrote results of treatment lumbar spinal stenosis. Results of treatment central, lateral, lateral recess or foramina stenos is, were not announced. In this study we were analyzed intensity recovery neurological sings sixth mounts after operation lumbar lateral recess stenosis. METHODS Diagnosis was establish after neurological examines, functional X-ray and CT of lumbar spine et electromyography lower extremities. We analyzed, also, and patients opinion about them condition and treatments. RESULTS It was noticed good recovery of neurogenic claudication, paresthesic and pain in leg. Local pain in lumbar spine and damages sensibilities were significant presents after therapy. It was registered opinion of good recovery in high grade stenosis and stenois associated with disc protrusion. CONCLUSION Nerve root decompression in stenotic lateral recess of lumbar spine could achieved removing part of hypertrophy artricular facets. Good recovery was achieved after operation and rehabilitations treatment. Some grade disability could stayed because damages snezibilitics and local pain in lumbar spine.

Bajerova, Keckova, Krajevska and Olsevska--female physicians pioneers which worked in B&H. Born in Czech Republic and Poland, they began her medical work far from B&H, and full affirmation of her job received in this area.

S. Mujagić, Jasmina Bećirović-Ibrišević, H. Huseinagić, Selma Jakupović

Isolated cavernous and venous angiomas are common vascular cerebral malformations but their association is less frequent. Presence of venous angioma enhances the risk of bleeding from cavernous angioma. Also, this association is important for surgical planning. While early extirpation of cavernous angioma is recommended, the associated venous angioma has to be preserved due to the possible venous infarction. We report a case of venous angioma associated with cavernous angioma revealed by magnetic resonance imaging after the administration of contrast material, which was not visualised on unenhanced MRI images. The importance of contrast administration in the diagnosis of venous angioma in a close vicinity of cavernous is emphasised in this report.

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