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MORRIS F. COLLEN (1913-2014) Morris F. Collen was born in St. Paul, Minnesota (1, 2). He attended the University of Minnesota, where he earned a bachelor's degree in electrical engineering in 1935. In 1938 he earned his MD “with distinction” from the School of Medicine and completed a residency in internal medicine at USC/ Los Angeles County General Hospital (3). Dr. Morris Collen has had a profound infl uence, not only on the creation of the fi eld of informatics, but also on healthcare delivery and the creation of new models of payment and prevention. Dr. Collen's remarkable career began in 1942 when he was selected by Dr. Sidney Garfi eld, a surgeon, to join him as an internist in a California group practice. Drs Garfi eld and Collen subsequently worked with the industrialist Henry Kaiser, who is credited with creating one of the fi rst comprehensive prepaid health plans for both offi ce and hospital care. This led to the establishment of Kaiser Permanente in the post-World War II period plus a comprehensive infrastructure of hospitals in the Bay Area near San Francisco and near Portland, Oregon. In the subsequent decades, the Kaiser organization grew to become a nationwide healthcare provider with millions of enrollees. Collen became a nationally recognized authority on the treatment of pneumonia during World War II. His gift for research showed early in his published studies in The Permanente Foundation Medical Bulletin of which he was long-time editor. After two decades as an internist with Kaiser Permanente, his career took a turn into early medical information technology. Morris Collen and his team set to work to automate the 10-year-old multiphasic health screening exam to develop a prototype electronic health record. Within a decade, Dr. Collen accumulated several millions of health checkup data sets on more than a million subjects, creating in the process not only a prototype electronic health record, but also a phenomenal and unique basis for research, and this despite the immaturity of the technology available in the fi fties and sixties. For the pursuit of the scientifi c aspects of his work, Dr. Collen founded the Medical Methods Research Division within Kaiser Permanente in Oakland, to which he added the Division of Technology Assessment in 1979 that he directed until his retirement in 1983, at age 70. He was elected to membership in the Institute of Medicine of the National Academy of Sciences (1971), and has served in many capacities on many committees of the National Library of Medicine (3). By the time of his retirement that year, Dr. Collen listed some 150 publications in his scientifi c output and had held appointments at multiple fi rst-class universities, including Johns Hopkins and Stanford. His work „Hospital Information Systems“ and „Multiphasic Health Testing Services“, both became classics. The Morris F. Collen Award is given each year, when appropriate, to pioneers in the fi eld of medical informatics who best exemplify the teaching and practice of Morrie Collen (3).

Lejla Zunic, I. Masic

Pharmacy practice is an ever-changing science and profession. We are witnessing many advancement of pharmacy technology, drug-related information and applied clinical pharmacy literature, which influence our every day's life. Thus, new knowledge generated by research and clinical experience widen the knowledge; change the understanding of drugs and their application in therapeutics and every days life. Thus, policy makers, pharmacists, clinicians and researchers must evaluate and use the information existing in the literature to implement in their healthcare delivery. This paper is prepared for pharmacy researchers and pharmacy students and analyzes the major principles of ethical conduct in general science and also closely related topics on ghost authorship, conflict of interest, assigning co-authorship, redundant/repetitive and duplicate publication. Furthermore, the paper provides an insight into fabrication and falsification of data, as the most common form of scientific fraud. Scientific misconduct goes against everything that normal scientific method wants to reach for and pharmacy practitioners as one the first line available health care professionals all round the world should be enough aware of its importance and details when they want to evaluate the medical and pharmaceutical literature and deliver unbiased and ethically published knowledge of drugs both for the research or during consultations for patients care.

M. Tirić-Čampara, F. Krupic, M. Biscevic, Emina Spahić, Kerima Maglajlija, Z. Masic, Lejla Zunic, I. Masic

ABSTRACT Technological diseases are diseases of the modern era. Some are caused by occupational exposures, and are marked with direct professional relation, or the action of harmful effects in the workplace. Due to the increasing incidence of these diseases on specific workplaces which may be caused by one or more causal factors present in the workplace today, these diseases are considered as professional diseases. Severity of technological disease usually responds to the level and duration of exposure, and usually occurs after many years of exposure to harmful factor. Technological diseases occur due to excessive work at the computer, or excessive use of keyboards and computer mice, especially the non-ergonomic ones. This paper deals with the diseases of the neck, shoulder, elbow and wrist (cervical radiculopathy, mouse shoulder and carpal tunnel syndrome), as is currently the most common diseases of technology in our country and abroad. These three diseases can be caused by long-term load and physical effort, and are tied to specific occupations, such as occupations associated with prolonged sitting, working at the computer and work related to the fixed telephone communication, as well as certain types of sports (tennis, golf and others).

I. Masic, F. Grémy, P. Reichertz

Health professionals are able to make right decision in right time only if they posses prompt, accurate and up to date information about health status of patients and general population. They also need knowledge and tools, computer and information technologies, for successful management of huge amount of information. Efficient management of information is of crucial importance for health policy and decision-making process, and to produce high quality results in public health and healthcare delivery. The book presents an original effort to summarize the basic knowledge about the history of medical informatics and informatics education in Europe and broader, development stages and influence of computer sciences on development of medical informatics. In addition, history and development of medical informatics in Croatia and in Bosnia and Herzegovina is also presented, as well as some basic facts about the establishment, importance and activities of the two key international associations–IMIA and EFMI. A broad list of 36 key actors, with brief biographies and photos, is included, as the most influential scientists and doyens in development of medical informatics worldwide. The authors of the book pay special tribute to four corypheés of medical informatics–Morris F. Collen, François Grémy, Peter L. Reichertz and Jean-Claude Healy. The book is fulfilling an important gap revealing the history and emphasizing the importance of medical informatics as a new scientific discipline with very fast development and implementation in health care sector. Health informatics is contributing remarkably in everyday practice of medical and public health professionals, in efficient management of huge and increasing amount of health information and general and specific medical knowledge toward improved quality of health care, as well as to professional and scientific competitiveness in Europe and broader. The knowledge of information technology is now part of general literacy. The 264 pages are distributed in 14 chapters with references and consulted literature added to each chapter. The book is directed toward medical and other professionals in biomedicine, especially the young doctors. The book can be used by students at all levels, from undergraduate to postgraduate master and doctoral studies, and professionals in various clinical disciplines and public health. The book can also be useful as a guideline for all medical and other professionals in biomedicine in conducting everyday activities and promoting of their professional and research work. Skopje, August 2014 Prof. Doncho Donev, MD, PhD BOOK REVIEW

I. Masic, M. Hadžiahmetović, D. Donev, Azis Pollhozani, N. Ramadani, A. Skopljak, Almir Pasagić, E. Roshi et al.

Introduction: Family medicine as a part of the primary health care is devoted to provide continuous and comprehensive health care to the individuals and families regardless of age, gender, types of diseases and affected system or part of the body. Special emphasis in such holistic approach is given to the prevention of diseases and health promotion. Family Medicine is the first step/link between doctors and patients within patients care as well as regular inspections/examinations and follow-up of the health status of healthy people. Most countries aspire to join the European Union and therefore adopting new regulations that are applied in the European Union. Aim: The aim of this study is to present the role and importance of family medicine, or where family medicine is today in 21 Century from the beginning of development in these countries. The study is designed as a descriptive epidemiological study with data from 10 countries of the former Communist bloc, Slovenia, Croatia, Bosnia and Herzegovina, Serbia, Montenegro, Macedonia, Kosovo, Albania, Bulgaria, Romania, Czech Republic, Slovakia and Hungary, just about half of them are members of the EU. We examined the following variables: socio-organizational indicators, health and educational indicators and health indicators. The data used refer to 2002 and as a source of data are used official data from reference WebPages of family medicine doctors associations, WONCA website (EURACT, EQuiP, EGPRN), WebPages of Bureau of Statistics of the countries where the research was conducted as well as the Ministries of Health. Results: Results indicates that the failures and shortcomings of health care organizations in Southeast Europe. Lack of money hinders the implementation of health care reform in all mentioned countries, the most of them that is more oriented to Bismarck financing system. Problems in the political, legal and economic levels are obstacles for efficient a problem reconstructing health care system toward family medicine and primary prevention interventions. The population is not enough educated for complicated enforcement for and prevention of diseases that have a heavy burden on the budget. Health insurance and payment of health services is often a problem, because the patients must be treated regardless of their insurance coverage and financial situation. The decrease in production and economic growth, as well as low gross national income in the countries with economic crisis, lead to the inability of treatment for a large number of the population. Such situation a system leads to additional debts and loans to healthcare system. Measures implemented for provision of acute curative care largely did not lead to improvements in the health status of the population. Educational and preventive measures, as well as higher standards for quality and accessibility of health care services for entire population in each country, especially those struggling are bound to joining the European Union and their implementation must start. The most A large number of medical institutions are is inefficient in health education and health promotion and must work to educate patients and families and increase the quality of preventive health services. Modernization of health care delivery and joining the European Union by increasing overall economic stability of countries is one of the primary goals of all countries in Southeast Europe.

M. Zildžić, N. Salihefendic, F. Krupic, Emina Beganovic, Lejla Zunic, I. Masic

Telemedicine itself is not the medical profession, it is not a medical specialty, but the way in which the medical profession conduct its activity. Therefore we are talking about tele otorhinolaryngology, tele cardiology or tele pathology. In the definition of a multitude of telemedicine that can be found in the literature is the following: Telemedicine is a system that supports the process of health care by providing ways and means for more efficient exchange of information that allows multitude of activities related to health care, including health care and health personnel, including education, administration and treatment. Telemedicine applications include tele diagnosis, tele consultation, tele monitoring, tele-care, tele consultations and remote access to information contained in one or more databases. It turned out that telemedicine is an important factor in technological, professional, financial and organizational uniformity of development of the health system. Telemedicine, although a new area, to a large extent already changed the ways of providing health care, and even more influence on the ways of designing the future of medicine.

I. Masic, Emina Karčić, A. Hodzic, Smaila Mulic

Introduction: Information and communication technology have brought about many changes in medical education and practice, especially in the field of diagnostics. During the academic year 2013/2014, at Faculty of Medicine, University of Sarajevo, students in the final year of the study were subjected to examination which aim was to determine how medical students in Bosnia and Herzegovina subjectively assessing their skills for using computers, have gained insight into the nature of Information Technology’s (IT) education and possessive knowledge. Material and methods: The survey was conducted voluntary by anonymous questionnaire consisting of 27 questions, divided into five categories, which are collecting facts about student’s: sex, age, year of entry, computer skills, possessing the same, the use of the Internet, the method of obtaining currently knowledge and recommendations of students in order to improve their IT training. Results of the study: According to the given parameters, indicate an obvious difference in the level of knowledge, use and practical application of Information Technology’s knowledge among students of the Bologna process to the students educated under the old system in favor of the first ones. Based on a comparison of similar studies conducted in Croatia, Sri Lanka, Pakistan and Denmark, it was observed that the level of knowledge of students of the Medical Faculty in Sarajevo was of equal height or greater than in these countries.

Recently at a meeting of the European Association of Science Editors Council, held in Split on June 13, 2014 I said that the editorial job in journals is serious, responsible, hard, and lately it also becomes dangerous. That job, really, requires, besides rich knowledge and experience, also “wasting” a lot of time, nerves and renunciation of all kinds in order that journals that we edit, in their final form are rich with content, contains articles of superior/high scientific quality, results of research that can interest potential readers and users of scientific published content, but also linguistically, aestheticly and technically acceptable to attract and meet the needs and taste of potential readers. All above mentioned is sometimes very easily unsuccessful or the efforts of the publishers, which have the teams of qualified and capable associates involved in at least six of technological stages–from submission, editing, linguistic and technical preparations, printing, converting in the XLM format for on-line databases and painstaking process of communication with authors and co-authors that sometimes become unsuccessful and very frustrating. Unfortunately, this last mentioned can make life difficult for the editor and shake or diminish his/hers sense of love and pleasures for this beautiful and above all socially useful, but hard work in all scientific and academic community centers in any country and at any level of its development.

I. Masic, A. Sabzghabaee

Fundamental components of scientific writing are accuracy, integrity, clarity and conciseness. Good scientific writing is represented by clearness, concise expression, accuracy of the report, and most importantly, honesty.[1] Academic honesty means that the work scientist submits, in whatever form, is original. However, one of the most common ways of compromising the academic integrity of the author and most widely recognized unethical lapse is plagiarism.[1] As there are no universal regulations on plagiarism prevention, it is important to cite references correctly. Citing materials that author has referred to correctly enables to avoid plagiarism and in the same time, to follow ethical, moral, and legal regulations acceptable by scientific community. True knowledge is gained through scientific research.[2,3,4] It seems that the highest aim of human knowledge is the ability to investigate problems scientifically.[5] Scientometrics is the study of measuring features and characteristics of science and scientific research. Normally, scientometrics is often made using some bibliometrics and measuring of the impact of scientific literature.[2,5] Scientometric procedures are increasingly used to analyze developments and trends in science and technology. Modern scientometrics is mostly based on the work of Derek J. de Solla Price and Eugene Garfield.[5] Garfield has been striving to mathematical representation developed several factors that allow the assessment value and importance of scientific publications, including the most important impact factor (IF) and the H-index.[5] Some of the indicators used in the evaluation of scientific research are: Impact factor Article citations Journal citations. Impact factor is the number of citations of articles published in the journal during the previous 2 years divided by the total number of articles published in the journal during the same period.[5] Factor of influence depends on: The quality of the journal, the language on which it was printed, the area it covers, and the magazine distribution system. IF in the academic journal is a measure that reflects the average number of citations of articles published in the journal. IF is used to compare different journals in a particular area.[5] In a given year, the IF of the journal is the average number of citations received per paper published in that journal during the previous 2 years. For example, if a journal IF = 3 in 2013, then the articles published in 2011 and the 2012 had three citations on average in 2013.[5] Impact factor for the 2013 of the journal will be calculated as follows: A = number of cited articles published in 2011 and 2012 in indexed journals during the year 2013. B = the total number of articles published by the journal in 2011 and 2012. 2013 IF = A/B.[5] H-index is an index that attempts to measure the productivity and impact of published work of scientists [Figure 1]. The index is based on the basis of the most cited papers and the number of citations that papers received in other publications.[5] This index can also be applied to the productivity and impact of a group of scientists, such as department or faculty, as well as journal. H-index proposed by Jorge E. Hirsch, a physicist at UCSD, as a tool for determining the relative quality.[5] Figure 1 H-index of the plot decreasing citations for numbered papers (http://en.wikipedia.org/wiki/File:H-index-en.svg) It is clear, from Table 1, that the H-index of the oldest Biomedical Journal Medical Archives is significantly higher with H-index of 10, which means that the scientist who in this magazine published 10 papers have at least 10 citations for each work in other journals. Table 1 Presentation of biomedical journals in B and H ordered by the H-index values One of the greatest, and sadly too common, problems that participants in the academic process encountered is plagiarism. The term plagiarism stems from the Latin word plagium, meaning kidnapping a man.[6] Literary, plagiarism means theft, taking material authored by others and presenting it as someone else's. American Association of university Professors defined plagiarism as “taking over the ideas, methods, or written words of another, without acknowledgment and with the intention that they be taken as the work of the deceiver” (September/October, 1989).[1] Academic honesty means that the work scientist submits, in whatever form, is original. Scientists are expected to build their work on that of other people. Giving credit to someone whose work has helped them is expected; in fact, not to give such credit is a crime. Plagiarism is the severest form of academic fraud.[1] According to the World Association of Medical Editors strict definition, plagiarism is when six consecutive words are copied, 7-11 words are overlapping set of 30 letters.[7] Generally speaking, plagiarism is when someone uses others’ ideas, statements, linguistic style and does not acknowledge intellectual originators. “Before the plagiarist taken as their own people's tables or text, today there is a growing interest in taking the ideas and concepts”.[8] Although plagiarism can take many forms there are two major types in scholarly writing: Plagiarism of ideas and plagiarism of words. Words plagiarism is divided into three categories: The direct form-completely or partially copying of text, computer files, audio or video recordings without acknowledging primary source Mosaic form — borrowing ideas and opinions from the original source, few words and phrases without citing this source; Self-plagiarism — reuse of one's own work without quotation and permission to reproduce text.[6] This is one of the most common ways of compromising the academic integrity of the author and cause of constant conflict in scientific-research sphere of interest. It is not enough to change a few words in a phrase from the source material into “own words.” Change the order of words in a sentence is also not acceptable, as well as the use of synonyms, such as changes from the “air” to “atmosphere.”[6] When writing papers, it is possible to use other people's words and ideas, but with mandatory labeling and reference to the source from which these words and ideas are taken. The references, as an indispensable part of any scientific and professional work, contribute to the quality of work, speaks of the sources used and thus the depth of information on the subject by which the work is dedicated.[6] There are no universal regulations on plagiarism prevention suitable for all scientific and academic institutions.[1] In order to avoid plagiarism, authors should: Follow rules of properly citing references; references must contain full bibliographic information; each source cited in the text must be listed in the bibliography; quotation marks should be used if more than 6 consecutive words are copied; obtain permission from other authors/publishers to reproduce copyright-protected graphics or text; it should be also noted that plagiarism can now be detected electronically (e.g., by use of CrossCheck of iThenticate).[6] Researchers rely on the published data, and have to be skilled to selectively process these data, to incorporate previous knowledge into a new paper, and to distinguish original ideas and research results from already publicized ones.[6] At the end of the assignment, author must list all the publications he/she has referred to (cited) in writing. This procedure is called citing or quoting references. Citing materials that author has referred to correctly enables to avoid plagiarism and in the same time, follow ethical, moral and legal regulations acceptable by scientific community.[1] In scientific circles, the reference is the information that is necessary to the reader in identifying and finding used sources. References must be accurate, complete and should be consistently applied.[1,9,10,11] There are many different styles of referencing. Often, the preferred system of citation is depended on the scientific discipline in which the author writes.[6,9,10,11] The most commonly used systems are “author-date” (such as the Harvard system, APA, etc.) and numerical systems (such as CSA, IEEE, Vancouver style and others). Each system includes a precisely defined set of rules for attribution in the text of scientific or professional work and a way of referring to them. The aim is to make it recognizable what, in the text, belongs to the author and what is taken from other authors/sources. Once adopted, one way of reference must be applied consistently throughout the text.[6,11] Although scientific writing is a complex and arduous process, it should be clear, accurate, honest, and concise. As is the case with most other human activities, errors can occur in scientific writing as well. In order to prevent the severest form of academic fraud — plagiarism — author must give credit to someone whose work has helped him/her by citing references correctly.

Lejla Zunic, Emina Karčić, I. Masic

During the medieval which is called the dark period of Western culture there were minimal scientific advancements in many aspects of medical and pharmaceutical sciences. In contrast, the Islamic culture in this period had its big boom. Although little attention was devoted to documenting all aspects of it, works produced during this period by the Islamic intellectuals have served as the basis for some aspects of Western Renaissance. Books, treatises, other types of manuscripts, and discussions have been translated into many languages and remained in use for hundreds of years after their creation. Although advanced, unfortunately, Muslims and their culture were not able to keep the places where they previously exist, and the best examples of this are the Moors.

D. Junuzović, Lejla Zunic, M. Dervisefendic, A. Skopljak, Almir Pasagić, I. Masic

Introduction: Antimicrobials are widely used in infectious diseases. Only the timely intervention will contribute to the positive outcome of the disease. Unjustified use of antimicrobial prophylaxis may have adverse effects, i.e., result in bacterial resistance to existing antimicrobials, as well as toxic effects on leukocyte lineage and other parameters of the blood. Goal: The goal of this study was to confirm that the antimicrobial therapy of urinary, gynecological and respiratory infections has a toxic effect on leukocyte lineage. Followed by lowered immunity and the emergence of risk for health complications especially in oncology and other immunodeficient patients for whom to apply pharmacotherapy it is necessary to have adequate immunity, or white blood cell count that is greater than 4.0x109/L. Material and methods: A prospective-retrospective study was conducted on a sample of 30 patients in a Primary Health Care Center in Gracanica during the period from March 01, 2013 until April 01, 2014. Testing of this sample was conducted by survey on health status and treatment, or on taking of antimicrobial therapy and other treatment regimens, with the referral diagnosis and determination of leukocytes count in by hematology counter SYSMEX. Results of leukocytes below and close to the lower reference values were statistically analyzed by Students t-test. Results: Mean WBC count in the group treated with antimicrobial therapy was 3.687±0.83 x109/L, in the group which during repeated infection did not use the antimicrobial therapy 5.09±1.04 x109/L, and in the control group of healthy subjects 7.178±1.038 x109/L. Statistical analysis with Student’s t test indicate highly significant differences between group of patients that used antimicrobial therapy with the group of patient that did not used antimicrobial during repeated infection (t=6.091; p=0.0001), as well as significant differences in mean WBC count of both of these groups and the controls (t=4.984; p=0.0001, and t=8.402, p=0.0001). Conclusion: Use of antimicrobial drugs leads to serious toxic reactions, or leukopenia. Indications for the use of antimicrobial therapy must be strictly followed, because banal, frequent infections are not indication for antimicrobial therapy. It is necessary to know the types of infection causes. Important is the proper and timely selection of antimicrobial therapy. When selecting the drug we should bear in mind its antimicrobial activity, pharmacokinetic and toxic properties, as well as patient health status. Possible is also the application of preventive medicine as well as other manner of solving infection.

I. Masic, A. Hodzic, Smaila Mulic

To present the basic principles and standards of Ethics in medical research and publishing, as well as the need for continuing education in the principles and ethics in science and publication in biomedicine. An analysis of relevant materials and documents, sources from the published literature. Investing in education of researches and potential researches, already in the level of medical schools. Educating them on research ethics, what constitutes research misconduct and the seriousness of it repercussion is essential for finding a solution to this problem and ensuring careers are constructed on honesty and integrity.

Quality is assessed on the basis of adequate evidence, while best results of the research are accomplished through scientific knowledge. Information contained in a scientific work must always be based on scientific evidence. Guidelines for genuine scientific research should be designed based on real results. Dynamic research and use correct methods of scientific work must originate from everyday practice and the fundamentals of the research. The original work should have the proper data sources with clearly defined research goals, methods of operation which are acceptable for questions included in the study. When selecting the methods it is necessary to obtain the consent of the patients/respondents to provide data for execution of the project or so called informed consent. Only by the own efforts can be reached true results, from which can be drawn conclusions and which finally can give a valid scholarly commentary. Text may be copied from other sources, either in whole or in part and marked as a result of the other studies. For high-quality scientific work necessary are expertise and relevant scientific literature, mostly taken from publications that are stored in biomedical databases. These are scientific, professional and review articles, case reports of disease in physician practices, but the knowledge can also be acquired on scientific and expert lectures by renowned scientists. Form of text publications must meet standards on writing a paper. If the article has already been published in a scientific journal, the same article cannot be published in any other journal with a few minor adjustments, or without specifying the parts of the first article which is used in another article. Copyright infringement occurs when the author of a new article, with or without mentioning the author, uses a substantial portion of previously published articles, including past contributions in the first article. With the permission of the publisher and the author, another journal can re-publish the article already published. In that case, that is not plagiarism, because the journal states that the article was re-published with the permission of the journal in which the article is primarily released. The original can be only one, and the copy is a copy, and plagiarism is stolen copy. The aim of combating plagiarism is to improve the quality, to achieve satisfactory results and to compare the results of their own research, rather than copying the data from the results of other people's research. Copy leads to incorrect results. Nowadays the problem of plagiarism has become huge, or widespread and present in almost all spheres of human activity, particularly in science. Scientific institutions and universities should have a center for surveillance, security, promotion and development of quality research. Establishment of rules and respect the rules of good practice are the obligations of each research institutions, universities and every individual researchers, regardless of which area of science is being investigated. There are misunderstandings and doubts about the criteria and standards for when and how to declare someone a plagiarist. European and World Association of Science Editors (EASE and WAME), and COPE - Committee on Publishing Ethics working on the precise definition of that institution or that the scientific committee may sanction when someone is proven plagiarism and familiarize the authors with the types of sanctions. The practice is to inform the editors about discovered plagiarism and articles are withdrawn from the database, while the authors are put on the so-called black list. So far this is the only way of preventing plagiarism, because there are no other sanctions.

n the year 2013 Acta Informatica Medica journal has published a total of 66 articles. Submission was carried out only electronically trough the Data Base Management System: www.scopemed.org. The journal has its own web site: www.avicenapublisher.org and it is possible to down-load full articles in PDF format. Most articles are from Bosnia and Herzegovina, but there is a signifi cant number published articles from other countries. A large number of articles was returned to authors due to linguistic and technical shortcomings, but also relatively poor scientifi c content. There is ongoing work on the promotion of peer reviewing process to prevent deceits, but also to improve journal scientometrics indicators (impact factor, citation of the article, journal citations, the number and order of au-thors in articles, etc.). Rejection rate was up to 46%.The structure of the articles published in the Acta Infor-matica Medica during 2013 was dominated by the original articles - 51, followed by case reports - 5, professional pa-pers - 4, reviews - 4. Each issue of the journal as a rule con-tain contributions such as: news, book reviews, in memo-riam etc. Last year is also published the Guidelines with professional and educational features (1, 2, 3).The authors of the article published in the Acta Infor-matica Medica in 2013 were from 16 countries: Bosnia and Herzegovina, Croatia, Serbia, Kosovo, Iran, Turkey, USA, Egypt, Albania, Macedonia, India, Greece, Slovenia, France, Brazil and Saudi Arabia. The ratio of articles by au-thors from Bosnia and Herzegovina and abroad is 21:79. According to the medical fi elds of the published articles, the largest number was from clinical medicine - 34, fol-lowed by articles from preclinical disciplines - 18 and Public Health - 14. The largest number of articles was from the fi eld of in-ternal medicine - 45,1%, then, surgery - 16,1%, Pediatrics - 16,1%, neuropsychiatry - 3,2%, gynecology and obstetrics - 3,2%, nuclear medicine - 3,2%, etc. Most frequently pub-lished papers were from Medica Informatics fi eld - 28,5%, then from Biochemistry - 14,3%, etc. The time period from acceptance to publication of articles (received/accepted time): 50-59 days was presented in 16 cases, then, 60-69 days in 15 cases, 40 -49 days in 6 cases, 80-89 days in 6 cases, while the interval - over 100 days was only in 3 cases. So, the largest number of papers was waiting for publication between 2 and 3 months. (fi gure 1, 2). The reviewers of the articles published in Acta Infor-matica Medica in 2013 were: • Damir Aganovic (BiH)• Omid Aghadavoudi (Iran)• Kenan Arnautovic (USA)• Mehmedali Azemi (Kosova)• Adem Balic (BiH)• Marion Ball (USA)• Rusmir Baljic (BiH)• Jacob Bergsland (Norway)• Alma Bravo (BiH)• Marko Buksa (BiH)• Genc Burazeri (Albania)• Vesna Cukic (BiH)• Vida Demarin (Croatia)• Doncho Donev (Macedonia)• Masoud Ferdosi (Iran)• Armen Yuri Gasparyan (UK)• Vjekoslav Gerc (BiH)• Zulfo Godinjak (BiH)• Mirko Grujic (BiH)

Francois Gremy (1929 2014) has a Master’s in Physical Sciences, a Master’s in Mathematics (1, 2). He was interned in Paris Hospitals as a Doctor of Medicine, and late he become University Professor at several universities in France. Diploma of Higher Education in Theory of Probabilities he received from the Statistical Institute of Paris (1, 2). Early in his career he worked at the Faculty of Medicine of Tours. This experience led him to the Faculty of Medicine, Pitié-Salpêtrièr, where for 23 years, he was professor of Biophysiques, Biostatistics and Medical Informatics, a hospital biologist and Department Head of Medical Informatics in Paris Hospitals, as well as Director of the U-88’s Research Unit: ‘Public Health and Economical and Social Epidemiology’ at INSERM. In the Faculty of Medicine at Montpellier-Nimes, Professor Grémy was Professor of Biostatistics and Medical Informatics, and Department Head of Bioinformatics at the Regional University Hospital Center, Montpellier. Between 1990 and 1996, in the same center, Professor Grémy was Professor of Public Health and Department Head of Medico-Hospital Economy and Preventive Actions. He was President of the Board of Directors of the National School of Public Health of Rennes, member of the National Universities’ Council of the High Committee of Public Health, and of the Scientific Council of PM.S–I. He founded in 1967 the International Medical Informatics Association (IMIA). He is also the co-founder of the European Federation for Medical Informatics, and served as a member in the European Commissions’ activities evaluating informatics technologies in medicine. His scientific career, is distinguished because of his significant contribution as a researcher and as a forerunner in the field. His influence has ranged from hard sciences to clinical medicine, and he is recognized as a philosopher among medical informaticians. He acquired specific competence in Cardiology and Neurology, especially in neurophysiology. But he also got degrees in mathematics, biophysics, and more recently philosophy. He created the first laboratory for Medical informatics in the mid-60s at the Pitié-Salpêtrière School of Medicine in Paris. As founder of IFIP TC4 that gave rise to IMIA he is considered to be the IMIA father and a key European figure in the field. During MEDINFO 2004 Conference in San Francisco Francois Gremy received the first IMIA Award of Excellence for his outstanding contributions to IMIA and to health informatics. François was one of the founders of IMIA and his extensive research especially during his time at the University of Montpellier had left a lasting impression on his colleagues, students and friends in Europe and many other parts of the world. Francis Gremy was not only a pioneer in the Medical/Health informatics as new field, he had a holistic view on the large variety of medical informatics applications, with humanistic values to be respected and ethical guidelines to propose to follow. His ability to clarify complex matters and his sense of humor were part of his great teacher talents, associated to his very open mind to perform research in a multidisciplinary approach. His social engagement was also exceptional. He was an emblematic figure who opened new roads leading to patient centered Medical informatics, one of the best examples of the French culture, a Master and a friend (2).” As the first President of IMIA and for his collaboration when he was President of the School of Public Health of Rennes, Université Catholique de Louvain, acknowledged his key-role in the development of Medical informatics by nominating him “Doctor Honoris Causa” (2). François Grémy deals with evaluation of health information systems, where he was involved and describes the evolution of his personal ideas. He proposes the main distinction between systems where the user(s) remain(s) external from the running program, from the ones where the user(s) interacting with the program become(s) the main component of the system (1). Francois Gremy "addresses conventional methods of evaluation used in Medical Technology Assessment, how the whole knowledge in anthropology may contribute strongly to evaluation, and how the subjectivity of the user(s), how he (or they) react(s) with the computing machinery, is a main key to the success or failure of the whole system. He asserts that the temptation of the eradication of subjectivity as a condition for progress is deleterious for our civilization threatened by a comeback of barbarity, and is scientifically wrong (1).” His honors include the Janssen Prize from the Academy of Medicine; Silver Core International Federation for Information Processing; Chevalier Legion of Honor; Prize in Medicine and Public Health from the Institute of Health Sciences; and an Honorary Doctorate from Catholic University in Louvain, Belgium (2).

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