OBJECTIVE Canine hip dysplasia (CHD) is a global disease and an improved diagnostic approach to this orthopedic condition is needed, with an emphasis on inexpensive and minimally invasive techniques. This research aimed to determine the differentiating potential of selected biochemical markers in serum between healthy dogs and dogs with hip dysplasia in a breed-specific study that involved the Tornjak dog population. ANIMALS 99 Tornjak dogs radiographically categorized (Federation Cynologique Internationale procedure and scoring scheme) between December 2019 and April 2021, as having no sign of hip dysplasia or near normal hip joints (nondysplastic group; n = 51) vs mild, moderate, or severe hip dysplasia (dysplastic group; 48). METHODS Serum concentrations and enzyme activity of the biochemical markers hyaluronic acid (HA), procollagen II C-terminal propeptide (PIICP), and metalloproteinase 9 (MMP9) were compared among adult dogs with or without radiographic hip dysplasia. Statistical tests used to examine the differentiating potential of biochemical markers in Tornjak dog groups were assessed using the Mann-Whitney U test, logistic regression, and receiving operating characteristics (ROC) analysis. RESULTS Tornjak dogs with radiographic CHD had significantly lower serum concentrations of HA and higher concentrations of PIICP and MMP9 activity compared to dogs with radiographically normal hips (P < .05). Selected biochemical markers could distinguish dogs with radiographic CHD from those without CHD with high sensitivity and specificity. CLINICAL RELEVANCE These data suggest that the diagnostic technique of measuring serum concentrations of HA, PIICP, and MMP9 activity has a selective ability to distinguish dogs with dysplastic from dogs with normal hips.

Concomitant injuries of bone and soft tissues of the upper and lower jaws are classified as multiple trauma symptoms associated with early complications, such as shock, disordered breathing, bleeding, pain, deformity and facial asymmetry, abnormal jaw movement, crepitation, palsy-paralysis of traumatized soft tissue regions and languages. The goal of this work is to present polytraumatised rehabilitation of upper and lower jaws by the system of endodontic treatment of upper canines in cats. Primary approach to stabilization polytraumatised cats is highlighted, also as procedures to be undertaken in animal in shock, injury of the maxilla and mandible, and the order of diagnostic procedures. Mandibular prognation and incorrect occlusion with consequent demage of mandibular gingiva with maxilla kaninus are complications wich were resolved in our case with endodontic treatment of upper canines of the cat. This paper presents a detailed approach to the reduction of dental caninus maxilla and establishing proper bite in the molar region of the maxila and mandible. [Projekat Ministarstva nauke Republike Srbije, br. III 45006]

During the last several decades radiation therapy of superficial tumors by megavoltage electron beams has been widely applied in human and veterinary medicine. The objective of our research was to investigate clinical and pathohistological changes in the rabbit skin during a 90-day period after a single local electron beam irradiation of posterior extremity, and to investigate the impact of the single application dose of irradiation on dynamics and severity of acute skin changes in rabbits. Experimental trial was conducted on 18 adult New Zealand white rabbit males divided into 3 groups of 6 rabbits, whose left posterior extremity was irradiated with a single total dose of 55, 65 and 75 Gy, respectively, on the field size 10x10 cm, using 6 MeV beams. Clinical observation of the skin changes during the 90-day postradiation period in all the three experimental groups of rabbits singly irradiated by megavoltage electron beams in total doses of 55, 65 i 75 Gy resulted in occurrence of epilation, erythema, dry desquamation, edema,  moist desquamation, secondary ulceration, and reparation. Severity of the main acute responses of the rabbit skin such as erythema, and dry and moist desquamation was proportional to the single high dose of megavoltage electron irradiation, and was reflected in time between irradiation to clinical symptoms as well as the duration of symptoms. Pathohistological changes in the rabbit skin and subcutaneous tissue were observed on the 20th, 50th, and 90th day upon irradiation, and their severity was growing in proportion with the dose (55, 65 i 75 Gy) following the dynamics and severity of the acute clinical skin changes. Key words: single irradiation by electron beams, early skin responses, rabbits

Canine hip dysplasia (CHD) is a hereditary developmental anomaly, most frequent in large dog breeds. Clinical confirmation of the disorder is based on hip X-ray imaging. Twenty Tornjak dogs aged between 9-36 months, and weighted from 35-42 kg were examined for CHD. Scoring was performed according to six clearly defined radiographic parameters by Flueckiger method (5). Dysplastic changes of various severity were observed in 11 dogs, while in 9 dogs changes were absent. The study describes 4 CHD cases of varying degrees of severity. The results indicate the presence of CHD in Bosnian Tornjak. Determining the incidence of dysplasia in this autochthonous breed requires a more detailed study, which will enable determination of the prevalence of dysplasia and analysis of the relationship to other dog breeds. Key words: canine hip dysplasia, Bosnian Tornjak

Bear (Ursus arctos) represent a common wild animal in the forests of our country, but also an attractive hunting wildlife. Because it is a powerful beast, wounding instead of killing is not uncommon during hunting or poaching. Bear who was shot in the head by poachers was urgently hospitalized at Clinics of Veterinary Faculty Sarajevo. This paper includes a description of the animal health condition, severity of injures, performed diagnostic methods and therapy. In this way, we want to emphasize the broad spectrum of veterinary practice and induce affirmation of the veterinary profession and science in the hunting management activity, as one of the segments where the veterinarians are required. Key words: Bear, trauma, therapy

Until now no study has been carried out to determine the presence of feline coronaviruses in Croatia. The aim of our study was to determine for the first time the presence of the FCoV infection. Seven blood samples from domestic cats were investigated for the presence of Feline Coronavirus (FCoV) antibody titres (FCoV–Ab 1:10, FCoV–Ab 1:100 and FCoV-Ab≥1:400). At the same time, the following hematologic parameters: total erythrocyte count, hemoglobin concentration, hematocrit, MCV, MCH, MCHC, total leukocyte and platelet count, were determined. FCoV-Ab 1:10 were found in two cats, while FCoV-Ab≥1:400 were determined in the other two cats. Hematological parameters in seven cats were within the normal range. Our results indicate that it is necessary to serologically research the extent of the FCoV infection on the statistically representative sample. Key words: cat, feline coronaviruses, seroprevalence

The present study examined the protective effect of radioprotector amifostine (aminopropil-aminoethil-tiophosphate) in lethally irradiated swine. Its application in a tolerant dose of 150 mg/kg i.m. 30 minutes prior to irradiation prevents the emergence of radiation-induced haemorrhagic diathesis. All the irradiated animals protected by amifostine have survived a 30-day experimental period. Patomorpohological and patohistological changes in the bone marrow, microcirculation and the small intestine were descibed both in the unprotected and the amifostine-protected swine. No pathological changes in the bone marrow or the microcirculation of protected animals were reported while only the signs of mild catarrhal inflammation in the intestine were noted following lethal irradiation of the unprotected animals. The dose of 150 mg/kg of amifostine causes profuse vomiting and the transient increase in the number of leucocytes and erytrocytes within 24 hours. Based on the results obtained in experiments and the references found in the relevant literature it can be concluded that amifostine is a very effective radioprotective agent even when applied in heavy- biomass animals. Key words: radiation, protection, swine, amifostine

The possibility of radiologic imaging of traumatized angiostructure of the posterior limbs in dogs was investigated. Arteriographic visualization of the tubular bones in patients with traumatic fractures and patients who underwent conservative or surgical treatment of the fractures, was done. Puncture and catheterization of the femoral artery were possible only when the artery was surgically exposed. The “Urotrast 75” contrast was administered through a human i.v. cannula placed in the opposite leg up to the bifurcation of the abdominal aorta into the iliac arteries. Manual replacement of the cassettes and mechanical injection of the contrast resulted in a satisfactory quality of the arteriographs of the posterior extremities. Arteriography may be used in tubular bone fractures to show severity and localization of dislocation, stenosis, or discontinuation of the arterial blood flow in the traumatized area. Similarly, microvascular changes of the callus may be displayed. The described arteriographic method may also be applied in examination of vascular damage in other anatomic sites. Key words: arteriography, fracture, dog