Aim To identify E. coli from chicken meat, establish their antibiotic resistance profiles and to confirm ESBL isolates with real time PCR, as well as to identify risk factors and farming practice associated with the antimicrobial resistance E. coli. Methods The study included 100 chicken skin samples collected randomly from retail supermarkets, butcheries and slaughterhouses. Disk susceptibility testing was performed using the Kirby-Bauer method. Detection of ESBL-producing isolates was performed with double disk synergy test. Molecular analysis of phenotypic ESBL-producing Escherichia coli strains was performed at 7500 real time PCR System. Molecular-genetic analysis included detection of CTX-M 1, 2, and 9 gene families and mutations in the TEM and SHV encoding extended spectrum β-lactamases. Results Prevalence of the phenotypic ESBL-producing E. coli isolates was 29%, and they exhibited remarkable sensitivity to carbapenems (100%) as well as to amikacin (93.10%). All ESBL-producing strains were multidrug resistant. Molecular analysis was performed as the final confirmation of the production of extended spectrum β - lactamases for 24 isolates out of 29 phenotypicaly ESBL-producing E. coli isolates. Conclusion It is important to pay attention to people's awareness of bacterial antimicrobial resistance in food chain, as well as to understand its effects on human health and the environment. Phenotypic and molecular analysis demonstrated the presence of ESBL-producing E. coli isolates from chicken skin samples.

Aim To investigate the association of ABO blood types and appearance of myocardial infarction (MI) among the population in Bosnia and Herzegovina. Methods This was a cross sectional study conducted at the Department for Cardiovascular Surgery at the Clinical Centre of the University of Sarajevo from January 1st to December 31st 2019. Patients were divided into two groups, defined by their blood type, A (N=91) and non-A (N=109). ABO blood groups were determined using standard agglutination techniques. Information regarding history of MI was taken from their medical documentation during the preparation for surgery. Results In total 200 patients were involved in this study. The study sample consisted of 151 (74.5%) males and 49 (25.5%) females. Mean age was 62.98 ± 7.73. Various risk factors associated with myocardial infarction were tobacco 92 (46.0%) and alcohol 54 (27.0%) consumption, obesity 77 (38.5%), diabetes mellitus 47 (23.5%) and hypertension 91 (45.3%). Being A blood type (OR=3.308; 95% Cl 1.317-8.311; p=0.011) and being male and having hypertension (OR=3.086; 95% Cl 1.262-7.545; p=0.013) significantly increased the risk for the development of MI among young adults. Patients with A blood type were significantly younger [median 58.0 vs. 63.0; U = 2738.5; p =0.027] when they developed MI compared to non-A blood type. Conclusion The age of myocardial infarction occurrence in the population of Bosnia and Herzegovina is lower in patients with blood group A compared to non-A blood types.

Aim To investigate quality of life and exposure to lifestyle risk factors of cancer patients in Bosnia and Herzegovina and a correlation of cancer type with lifestyle risk factors. Methods This was a cross-sectional study conducted on 200 cancer patients from the Clinical Centre of the University of Sarajevo. The respondents completed an anonymous questionnaire consisting of seven sections: basic patient information, physical activity, dietary habits including alternative medicine, tobacco use, alcohol consumption, anxiety, and comorbidities. Results A total of 150 (75%) patients were overweight with 113 (56%) of them being less physically active after the confirmed diagnosis. After the diagnosis, 79 (40%) patients ate less food, and 154 (77%) healthier; 130 (65%) reported consumption of alternative medicine and food supplements, 39 (30%) spent >1/4 of average monthly salary on these products. Majority never consumed alcohol, 135 (68%) and 101 (51%) patients reported history of tobacco use. Being obese was an independent predictor for colorectal carcinoma; being less obese was linked to a decreased risk of breast cancer diagnosis. Physical activity was linked to a decreased risk of lung cancer diagnosis. Many patients (122; 61%) reported having chronic comorbidities, mostly hypertension, while 44 (22%) patients were proven to be clinically anxious. Conclusion Our data suggest lack of public awareness of the consequences of unhealthy lifestyles. Risk factors such as alcohol consumption and tobacco use differed from other European countries. Significance of lifestyle changes after the diagnosis for reducing mortality and cancer recurrence requires further research. Prevention programs and more data are needed.

Aim To examine whether preoperative tumour size may serve as a biomarker for the occurrence of lymphovascular invasion (LVI) in centrally and peripherally located lung adenocarcinoma. Method The study included 261 patients surgically treated for diagnosed lung adenocarcinoma. A ROC curve was used to determine the biomarker potential of tumour size relative to the occurrence of LVI. Binary logistic regression was used to show changes of tumour size impact on the status of LVI. Result Tumour prevalence according to localization had no statistical significance (p=0.464), while the presence of LVI in central, as well as peripheral positions, was statistically significantly different (p<0.001). The area under the curve of 0.978 highlights the fact that tumour size is an excellent marker of the presence of LVI in centrally located adenocarcinomas of the lung. A similar finding was confirmed in peripherally located lung adenocarcinomas with an area below the curve of 0.943. Binary logistical regression showed that in centrally localized adenocarcinomas of the lung, each additional centimetre of tumour growth represents an increase in the likelihood of LVI+ by 17.14 times. In peripherally located adenocarcinomas of the lung, this increase in likelihood of LVI for each centimetre of growth was 5.46 times. Conclusion With a high degree of sensitivity and specificity, preoperative tumour size may serve as an important biomarker and positive predictor of the presence of LVI in lung adenocarcinoma of any location.

This paper aims to examine the impact of digital tools in mathematics and the readiness of teachers and students applying these interactive tools in teaching. The data used in the research are obtained from the test results of 526 students, in five secondary schools in North Macedonia. The students in this research, are divided into two groups: mainly as a control group and an experimental group. The control group is the group of students who do not have access to the interactive tools at home and who use interactive tools only once a week in the school while the group of students in the experimental group have access to them and have the opportunity to use these interactive applications every day. The students in the control group and the experimental group were selected from the same year and the gender equality of the groups was taken into account. To further understand the relationship between teaching with digital tools and learning after testing was surveyed the participants. The results in our research suggest that interactive teaching tools have a positive impact on the teaching process and increase students' knowledge.

In this short demo paper, we introduce godash 2.0 godash is a headless HTTP adaptive streaming (HAS) video streaming platform written in the Google programming language GO. godash has been extensively rewritten for this release so as to provide ease of use, and a host of new features. godash includes options for eight different state of the art adaptive algorithms, five HAS profiles, four video codecs, the ability to stream audio and video segments, two transport protocols (TCP and QUIC), realtime output from five Quality of Experience (QoE) models, as well as a collaborative framework for the evaluation of cooperative HAS streaming. In this demo, we will introduce each of the options available in the godash configuration file, and illustrate examples of how to use the collaborative players using both godash on a native machine as well as godash within godashbed. godashbed is an integrated large-scale testbed framework for the evaluation of HAS streaming, which uses a virtual environment to serve video content locally (which allows setting security certificates) through the Mininet virtual emulation tool. In this manner, godash provides a framework for rapid deployment and testing of new HAS algorithms, QoE models and transport protocols.

Manufacturers of automated systems and their components have been allocating an enormous amount of time and effort in R&D activities. This effort translates into an overhead on the V&V (verification and validation) process making it time-consuming and costly. In this paper, we present an ECSEL JU project (VALU3S) that aims to evaluate the state-of-the-art V&V methods and tools, and design a multi-domain framework to create a clear structure around the components and elements needed to conduct the V&V process. The main expected benefit of the framework is to reduce time and cost needed to verify and validate automated systems with respect to safety, cyber-security, and privacy requirements. This is done through identification and classification of evaluation methods, tools, environments and concepts for V&V of automated systems with respect to the mentioned requirements. To this end, VALU3S brings together a consortium with partners from 10 different countries, amounting to a mix of 25 industrial partners, 6 leading research institutes, and 10 universities to reach the project goal.

In this paper, we present our work in close-distance non-verbal communication with tabletop robot Haru through hand gestural interaction. We implemented a novel hand gestural understanding system by training a machine-learning architecture for real-time hand gesture recognition with the Leap Motion. The proposed system is activated based on the velocity of a user's palm and index finger movement, and subsequently labels the detected movement segments under an early classification scheme. Our system is able to combine multiple gesture labels for recognition of consecutive gestures without clear movement boundaries. System evaluation is conducted on data simulating real human-robot interaction conditions, taking into account relevant performance variables such as movement style, timing and posture. Our results show robustness in hand gesture classification performance under variant conditions. We furthermore examine system behavior under sequential data input, paving the way towards seamless and natural real-time close-distance hand-gestural communication in the future.

The importance of agility in futsal is already recognized, but there is an evident lack of information about applicability of futsal specific tests. The aim of this study was to evaluate reliability, validity and correlates of tests evaluating the futsal specific pre-planned agility (PPA), and non-planned agility (NPA). The sample comprised 40 professional futsal players who were tested on newly developed tests of PPA and NPA, sprint over 10 meters, countermovement jump, body height and mass. The reliability analyses included calculation of intra-session Cronbach Alpha (CA) and Inter-Item-Correlation (IIR), as well as analysis (ANOVA) for repeated measurements. Differences between performance groups (starters [first team] vs. non-starters [substitutes]) were evidenced by t-test for independent samples and calculation of Effect Size differences (ES). Pearson’s product moment correlation was calculated to define associations between variables. The reliability of agility tests was appropriate, with somewhat better reliability of PPA (CA: 0.81 and 0.76, IIR: 0.79 and 0.72, for PPA and NPA, respectively). ANOVA did not reveal any significant differences among testing trials. Starters were had better PPA than non-starters (t-test: 1.98, p < 0.01, moderate ES). The PPA and NPA shared less than 40% of the common variance, which suggests that these capacities are independent. Jumping and sprinting were not significantly correlated to PPA and NPA. Study confirmed appropriate reliability of the newly developed tests, and applicability of the PPA in distinguishing performance-levels. Further studies in females and younger players are warranted.

Background The aim of the study was to address the working population with an occupational stress prevention program using mHealth solution and encourage them for healthy lifestyle choices. Methods Seventeen participants were randomized from the corporate setting. A 24alife app with a good compliance program was selected. Test battery has been designed to test the physical readiness, psychological evaluation and biological blood markers for stress. Participants were followed up after 30, 60 and 90 days, respectively, within the intervention period. Weight of participants was tracked three times per month. Univariate analysis compared the continuous variables by One-Way Repeated-Measures ANOVA test when the data were normally distributed, or Wilcoxon rank sum test for abnormal distribution of variables. Results Participants used the app with a compliance rate of 94.1%. The psychological evaluation revealed higher motivation for work, lower burnout scores and participants gave subjective responses of better general wellbeing. Some of the participants lost up to four kg of body mass. Physical readiness has also improved. Conclusions Results of mHealth projects on corporate could include primary health care institutions and health ministry to extend the existing system to patients’ pockets where they can monitor their disease and increase the ability of self-care.