Abstract The field of business ethics has received considerable attention from the corporate, academic, and public sectors over the past several decades. A key purpose of this paper is to examine existing research and knowledge creation in the field of business ethics. The paper includes systematic literature review using bibliomteric analysis which covers 50 articles, published in 11 peer-reviewed journals from 1994 to 2019, examining the methodological and theoretical approaches, as well as the main research focus areas. We found significant amount of studies concerning business ethics appeared mostly in business ethics journals. We identified seven areas of research covered by numerous authors in the observed period, of which three predominate: corporate culture; education; and national (cultural) approach to business ethics.
International Accounting Standard 19 - Employee Benefits outlines the accounting requirements for employee benefits, including short-term benefits, post-employment benefits, other long-term benefits and termination benefits. The standard establishes the principle that the cost of providing employee benefits should be recognized in the period in which the benefit is earned by the employee, rather than when it is paid or payable, and outlines how each category of employee benefits is measured. Aim of the paper is to determine the degree of IAS 19 implementation in Federation of Bosnia and Herzegovina, and its impact on financial performance of public enterprises. Since no significant negative impact of the implementation of IAS 19 on the financial performance has been proven, it could be recommended that the observed entities consider all its advantages and thus realize the potential benefits for both, the company and the employees.
Background: Miller Fisher syndrome (MFS) is a variant of Guillain-Barré syndrome and is characterised by a clinical triad of ophthalmoplegia, ataxia and areflexia. Objectives: This report presents an atypical case of MFS characterized by ocular and gastrointestinal involvement, and anti-ganglioside antibody-positivity. Methods: A 17-year old boy was referred to our ophthalmology emergency room with signs and symptoms of diplopia and upper lid ptosis of the right eye. He underwent a complete ophthalmologic examination with special reference to strabologic status, as well as a neuropediatric examination with serum antiganglioside antibody panel. Results: Strabologic examination showed horisontal diplopia (near and far), ptosis of the upper eyelid on the right and bilateral ophthalmoplegia (limited elevation). Orthoptic examination revealed esotropia of 8 prism dioptres (PD) at near and 18 PD at far distance. A pediatric neurologist found normal limb power, deep tendon reflexes and flexor plantar responses, but attenuated right patellar reflex. Serum anti-GQ1b IgG (+++), anti-GQ1b IgM (++) and anti-GD1a IgM(++) were positive. Positivity of anti-GQ1b IgG antibody confirmed the existence of incomplete MFS. We treated the patient with systemic intravenous immunoglobulins for five days, and after five months of follow-up, all symptoms resolved. Conclusion: MFS can present itself as a wide range of clinical features and its timely recognition is important. Despite the alarming nature of the disease, patients with MFS tend to have a good recovery of presented symptoms, and without any significant residual deficit.
Micellar systems are colloids with significant properties for pharmaceutical and food applications. They can be used to formulate thermodynamically stable mixtures to solubilize hydrophobic food-related substances. Furthermore, micellar formation is a complex process in which a variety of intermolecular interactions determine the course of formation and most important are the hydrophobic and hydrophilic interactions between surfactant–solvent and solvent–solvent. Glycols are organic compounds that belong to the group of alcohols. Among them, propane-1,2-diol (PG) is a substance commonly used as a food additive or ingredient in many cosmetic and hygiene products. The nature of the additive influences the micellar structure and properties of sodium dodecyl sulfate (SDS). When increasing the mass fraction of propane-1,2-diol in binary mixtures, the c.m.c. values decrease because propane-1,2-diol is a polar solvent, which gives it the ability to form hydrogen bonds, decreasing the cohesivity of water and reducing the dielectric constant of the aqueous phase. The values of ΔGm0 are negative in all mixed solvents according to the reduction in solvophobic interactions and increase in electrostatic interaction. With the rising concentration of cosolvent, the equilibrium between cosolvent in bulk solution and in the formed micelles is on the side of micelles, leading to the formation of micelles at a lower concentration with a small change in micellar size. According to the 1H NMR, with the addition of propylene glycol, there is a slight shift of SDS peaks towards lower ppm regions in comparison to the D2O peak. The shift is more evident with the increase in the amount of added propane-1,2-diol in comparison to the NMR spectra of pure SDS. Addition of propane-1,2-diol causes the upfield shift of the protons associated with hydrophilic groups, causing the shielding effect. This signifies that the alcohol is linked with the polar head groups of SDS due to its proximity to the SDS molecules.
Background: Arteriovenous malformation (bAVM) presents maldevelopment of the brain’s vessels with a direct connection between cerebral arteries and veins. By current data, patients from Spetzler Ponce A (SP) are found to benefit from the treatment. Considering the outcome, most of SP C and some of the SP B are the most debatable. Objective: Arteriovenous malformation presents maldevelopment of the brain’s vessels with a consequent direct connection between cerebral arteries and veins. The annual risk of hemorrhage in adults is reported for 2-3 %. They usually present with unilateral headaches seizures and intracranial hemorrhage. By current data, patients from Spetzler Ponce A (SP) are found to benefit from the treatment. Considering the outcome, most of SP C and some of the SP B are the most debatable. Methods: The study included a cohort of bAVM patients referred to Fujita Health University Bantane Hotokukai Hospital, Nagoya, Aichi, Japan where the main author (AA) has completed an international cerebrovascular fellowship under the mentorship of Professor Yoko Kato. Japanese Stroke Guidelines (JSG) were used for the treatment decision. Patients were graded according to the Spetzler Ponce (SP) system. Considering American Heart Association criteria (AHA), embolization was used as a part of multimodal treatment. Intraoperative microscopic video tools included Indocyanine green ICG, FLOW 800 and dual image video angiography DIVA. Clinical outcomes were measured using Modified Ranking Score (mRs). Results: A total of eleven patients with brain bAVM were studied with a median age of 32 years [IQR = 22-52]. There were ten patients presented with supratentorial and a single patient with infratentorial AVM. Patients were graded according to the Spetzler Ponce (SP) system. There were eight patients in SP A (72,7%), one in group B (9 %) while the rest of them were in C (18 %). Two patients had associated aneurysms that required treatment. The median size of the AVM nidus was 3,50 cm [IQR= 2-5]. Deep venous drainage was found in six patients while three were located in eloquent zones. Clinical outcomes were considered good by mRs <2 in eight patients, seven from the surgically treated group (72,7 % respectively). Surgery median length time was 427, 5 minutes; [IQR =320 - 463] with complete AVM resection in all patients and no mortality recorded in this cohort with the median follow up of 39,5 months [IQR = 19-59]. Conclusion: Ideal management of bAVM is still controversial. Those complex vascular lesions require multimodal treatment in a majority of cases in highly specialized centers. In SP A patients, surgery provides the best results with a positive outcome and a small number of complications. With the improvement of endovascular feeder occlusion SP B patients become prone to a more positive outcome. Nowadays, intraoperative microscopic tools such as FLOW 800, ICG and DIVA are irreplaceable while improving safety to deal with bAVM. For SP C patients, a combination of endovascular and stereotactic radiosurgery was found to be a good option in the present time.
Synovitis of the knee synovium is proven to be a precursor of knee osteoarthritis (OA), leading to a radiologically advanced stage of the disease. This study was conducted to elucidate the expression pattern of different inflammatory factors—NF-kB, iNOS, and MMP-9 in a subpopulation of synovial cells. Thirty synovial membrane intra-operative biopsies of patients (ten controls, ten with early OA, and ten with advanced OA, according to the Kellgren–Lawrence radiological score) were immunohistochemically stained for NF-kB, iNOS, and MMP9, and for different cell markers for macrophages, fibroblasts, leukocytes, lymphocytes, blood vessel endothelial cells, and blood vessel smooth muscle cells. The total number of CD68+/NF-kB+ cells/mm2 in the intima of early OA patients (median = 2359) was significantly higher compared to the total number of vimentin+/Nf-kB+ cells/mm2 (median = 1321) and LCA+/NF-kB+ cells/mm2 (median = 64) (p < 0.001 and p < 0.0001, respectively). The total number of LCA+/NF-kB+ cells/mm2 in the subintima of advanced OA patients (median = 2123) was significantly higher compared to the total number of vimentin+/NF-kB+ cells/mm2 (median = 14) and CD68+/NF-kB+ cells/mm2 (median = 29) (p < 0.0001). The total number of CD68+/iNOS+ cells/mm2 in the intima of both early and advanced OA patients was significantly higher compared to the total number of vimentin+/iNOS+ cells/mm2 and LCA+/iNOS+ cells/mm2 (p < 0.0001 and p < 0.001, respectively). The total number of CD68+/MMP-9+ cells/mm2 in the intima of both early and advanced OA patients was significantly higher compared to the total number of vimentin+/MMP-9+ cells/mm2 and CD5+/MMP-9+ cells/mm2 (p < 0.0001). Macrophages may have a leading role in OA progression through the NF-kB production of inflammatory factors (iNOS and MMP-9) in the intima, except in advanced OA, where leukocytes could have a dominant role through NF-kB production in subintima. The blocking of macrophageal and leukocyte NF-kB expression is a possible therapeutic target as a disease modifying drug.
The study’s primary purpose was to explore the abrasive water jet (AWJ) cut machinability of stainless steel X5CrNi18-10 (1.4301). The study analyzed the effects of such process parameters as the traverse speed (TS), the depth of cut (DC), and the abrasive mass flow rate (AR) on the surface roughness (Ra) concerning the thickness of the workpiece. Three different thicknesses were cut under different conditions; the Ra was measured at the top, in the middle, and the bottom of the cut. Experimental results were used in the developed feed-forward artificial neural network (ANN) to predict the Ra. The ANN’s model was validated using k-fold cross-validation. A lowest test root mean squared error (RMSE) of 0.2084 was achieved. The results of the predicted Ra by the ANN model and the results of the experimental data were compared. Additionally, as TS and DC were recognized, analysis of variance at a 95% confidence level was used to determine the most significant factors. Consequently, the ANN input parameters were modified, resulting in improved prediction; results show that the proposed model could be a useful tool for optimizing AWJ cut process parameters for predicting Ra. Its main advantage is the reduced time needed for experimentation.
Abstract Ion cyclotron resonance heating (ICRH) is one of the three additional heating schemes to be deployed on ITER. Its two antenna arrays, installed on the outboard midplane, will deliver 20 MW of RF power in the 40–55 MHz frequency range. The plasma-facing component of the antenna assembly is the Faraday screen, comprising beryllium (Be) tile armoured, actively cooled bars located only ~1 cm radially behind the innermost point of the shaped Be first wall panels (FWPs). As such they are in close proximity to the scrape-off layer (SOL) plasma and it is important to assess the maximum heat loads that the screen bars may experience during high power ITER operation. This paper provides a detailed assessment of these loads using the new 3D field line tracing and power deposition framework SMITER (Kos et al., 2019). The focus is on the H-mode, burning plasma scenario, taking into account both plasma heat loading (including average loading due to mitigated Type I ELMs) and the loads due to photonic impact (assessed with the optical ray-tracing package Raysect (Meakins and Carr, 2017)) from power radiated in the core obtained from integrated JINTRAC simulations. Calculations are also performed to assess the minimum allowed antenna to magnetic separatrix distances, for cases in which closer approach may be required to improve RF coupling.
The processes of salinisation and alkalinisation of soil that caused the formation of different types of saline (halomorphic) soils are characteristic of the northern part of Serbia — the area of Vojvodina. These soils are characterized by poor physical and chemical properties due to a high content of salt and/or adsorbed Na+ ions because of which are being used to a limited extent in agricultural production, and more as pastures. From the aspect of pedogenetic conditions, loess deposits and alluvial terraces of large rivers (Danube, Sava and Tisza) as aeolian-glacial sediments are the most widespread parent rock on which saline soils were formed. In addition, arid climate including geomorphological, hydrological and hydro-geochemical conditions were the main factors of the formation of saline areas of Vojvodina. These processes can also occur as a result of the poor irrigation. The increase in the average annual and summer air temperature during the period 1981–2017 compared to 1961−1990 was recorded as well as more inequality in the precipitation regime in spatial distribution and increased evapotranspiration. Under such conditions the areas of saline soils will be certainly further expanding. According to the results of previous pedological research, saline soils cover about 10% of the total soil surface of Vojvodina. In the last few decades the extensive research has been conducted on the process of soil salinisation in the area of Vojvodina including qualitative and quantitative composition of salt in various systematic soil units. They have shown the possibility of transforming saline soils into productive soils through the application of complex land reclamation measures which require substantial financial and long-term time investments.
The most recent development in the underlying QUIC transport protocol has revived the interest in HTTP over QUIC (HTTP/3) as a communication protocol solution in cloud and edge computing. This development is notable especially given the rise in implementations of IoT edge/cloud continuum, a new computing paradigm that extends the cloud computing IoT via edge computing systems. In IoT cloud/edge continuum, benchmarking performance of the communication protocol of choice is critical. We focus for the first time on experimental benchmarking of HTTP/3 performance in an IoT cloud/edge continuum system. To benchmark the performance in terms of scalability and latency, we first implement HTTP/3 from a set of non-standardized open-source libraries, - which is challenge, and use the implementation in two main IoT scenarios: edge computing only (IoT devices running HTTP/3 clients and edge devices running an HTTP/3 server), and cloud/edge continuum (based on Google Firebase). Experimental results show that latency and scalability remain a challenge for HTTP/3, but its appeal also remains, in its wide adoption, embedded security and compatibility with existing networked systems.
Abstract It is currently unknown how automated vehicle platoons will be perceived by other road users in their vicinity. This study explores how drivers of manually operated passenger cars interact with automated passenger car platoons while merging onto a highway, and how different inter-vehicular gaps between the platooning vehicles affect their experience and safety. The study was conducted in a driving simulator and involved 16 drivers of manually operated cars. Our results show that the drivers found the interactions mentally demanding, unsafe, and uncomfortable. They commonly expected that the platoon would adapt its behavior to accommodate a smooth merge. They also expressed a need for additional information about the platoon to easier anticipate its behavior and avoid cutting-in. This was, however, affected by the gap size; larger gaps (30 and 42.5 m) yielded better experience, more frequent cut-ins, and less crashes than the shorter gaps (15 and 22.5 m). A conclusion is that a short gap as well as external human–machine interfaces (eHMI) might be used to communicate the platoon’s intent to “stay together”, which in turn might prevent drivers from cutting-in. On the contrary, if the goal is to facilitate frequent, safe, and pleasant cut-ins, gaps larger than 22.5 m may be suitable. To thoroughly inform such design trade-offs, we urge for more research on this topic.
In this manuscript, distance and position estimation problems are investigated for visible light positioning (VLP) systems with red-green-blue (RGB) light emitting diodes (LEDs). The accuracy limits on distance and position estimation are calculated in terms of the Cramer-Rao lower bound (CRLB) for three different scenarios. Scenario~1 and Scenario~2 correspond to synchronous and asynchronous systems, respectively, with known channel attenuation formulas at the receiver. In Scenario~3, a synchronous system is considered but channel attenuation formulas are not known at the receiver. The derived CRLB expressions reveal the relations among distance/position estimation accuracies in the considered scenarios and lead to intuitive explanations for the benefits of using RGB LEDs. In addition, maximum likelihood (ML) estimators are derived in all scenarios, and it is shown that they can achieve close performance to the CRLBs in some cases for sufficiently high source optical powers.
The bone healing process following osteotomy may vary according to the type of surgical instrumentation. The aim of the present in vivo study was to determine thermal changes of the bone tissue following osteotomies performed by Er:YAG laser ablation in contact and non-contact modes, piezoelectric surgery, and surgical drill using an infrared thermographic camera. For each measurement, the temperature before the osteotomy-baseline (Tbase) and the maximal temperature measured during osteotomy (Tmax) were determined. Mean temperature (ΔT) values were calculated for each osteotomy technique. The significance of the difference of the registered temperature between groups was assessed by the ANOVA test for repeated measures. Mean baseline temperature (Tbase) was 27.9 ± 0.3 °C for contact Er:YAG laser, 29.9 ± 0.3 °C for non-contact Er:YAG laser, 29.4 ± 0.3 °C for piezosurgery, and 28.3 ± 0.3 °C for surgical drill. Mean maximum temperature (Tmax) was 29.9 ± 0.5 °C (ΔT = 1.9 ± 0.3 °C) for contact Er:YAG laser, 79.1 ± 4.6 °C (ΔT = 49.1 ± 4.4 °C) for non-contact Er:YAG laser, 29.1 ± 0.2 °C (ΔT = −0.2 ± 0.3 °C) for piezosurgery, and 27.3 ± 0.4 °C (ΔT = −0.9 ± 0.4 °C) for surgical drill. Statistically significant temperature changes were observed for the non-contact laser. The results of the study showed beneficial effects of the osteotomy performed by the Er:YAG laser used in the contact mode of working as well as for piezosurgery, reducing the potential overheating of the bone tissue as determined by means of infrared thermography.
A popular design framework for networked control systems (NCSs) is the emulation-based approach combined with Lyapunov-based analysis techniques for hybrid systems. In virtually all papers that use this framework, bounds in terms of the maximal allowable transmission interval (MATI) are provided to guarantee stability, and performance properties of the NCS. However, having only such a MATI condition is rather restrictive, and unrealistic in practice due to various network effects such as packet losses, leading to conservative bounds. In this article, we therefore consider an alternative condition on the communication instants to better capture the time-varying properties of the transmission intervals. In particular, we propose, in addition to the existence of a MATI, to also impose a bound on the average allowable transmission interval, expressed in terms of a reverse average dwell-time condition on the transmission intervals. We demonstrate by means of a novel Lyapunov-based analysis that stability of the NCS can still be guaranteed under this different condition on the transmission intervals, which can, in addition, lead to a significant improvement of the MATI. The strengths of these new results will be illustrated on a numerical example.
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