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SUMMARY The 4th Congress of Infectiologists of Bosnia-Herzegovina with international participation was held in Konjic, on 30. May to 02. June 2012. In addition to the prominent infectious disease experts from almost all university centers in B&H, the teachers at medical schools in Bosnia-Herzegovina, infectious disease specialists who work in health institutions in B&H, this Congress was attended by infectious disease experts from Serbia (12 participants), Turkey (3 participants), Croatia (3 participants), Macedonia (3 participants), Germany (2 participants) and Montenegro (2 participants). Topics included: Infections of the skin, soft tissue and bones, Sepsis and endocarditis, Infectious diseases emergencies and pediatric infectology, Emerging and reemerging infectious diseases, Hospital infections, Sexualy transmitted diseases, Infectious diagnostic and therapeutic protocols. Participating invited speakers were following professors: Salih Hosoglu (Turkey), Hakan Leblebicioglu (Turkey), Resat Ozaras (Turkey), Karsten Plötz (Germany), Ilija Kuzman (Croatia), Bruno Baršić (Croatia), Goran Tešović (Croatia). In addition to experts in infectious diseases at this Congress, their works were presented by experts from other medical disciplines, but with infectious character issues (Professors: Sead Ahmetagić, Ismet Gavrankapetanović, Zora Vukobrat-Bijedić, Senija Rašić, Halima Resić, Adnan Kapidžić, Ivo Curić, Jelena Ravlija, Amela Begić, Izet Mašić, Sadeta Hamzić, and others). Some of the papers that were presented at this Congress have been published in extenso, in the Medical Archives and Materia Socio Medica. One part as abstracts (both journals are indexed in over 10 databases), and will be electronically available to the general scientific community in Bosnia-Herzegovina, Europe and worldwide. In this way, the Bosnian infectious disease experts, as a science and profession, will be worthily represented to the colleagues from other countries in the region and beyond.

SUMMARY CONFLICT OF INTEREST: none declared There is a relatively low amount of historical data about development of infectology in Bosnia and Herzegovina, but that does not mean that these medical disciplines didn’t have important events and actors that are important for the development of this medical discipline in B&H. In this review we intent to show your several characteristic events and important persons, which left a lasting impression in the development of infectology service in BIH and especially in Sarajevo. Development center for this discipline was in Sarajevo. Experts on infectious diseases were sent from Sarajevo to other health centers to organize new ministry there. Infectology as an organized health care dates back to the Austro-Hungarian period, when a part of the State Hospital in Sarajevo formed a separate Department of Infectious Diseases. Thanks to the competent professional and later teaching staff in this discipline and the importance of health care of patients with infectious diseases, in Sarajevo and other cities in Bosnia, infectious diseases care has experienced expansion and increasing importance and quality. Infectious disease specialists were very quick in organizing their professional association and with exchange of knowledge and experience have contributed substantially to the above assertion. The “Association of infectious diseases of Bosnia and Herzegovina” was founded during the aggression on BIH, in 1994 and in 1997 they organized the first scientific congress of the Association of the infectious disease specialist with international participation. Improving the health of the population in the area of infectious diseases was significantly helped by infectious diseases clinics at clinical centers in BIH and departments for infectious diseases within the hospitals in B&H. Association of the infectious disease is a significant coordinator for scientific and professional activities, but also the environment in which infectious disease specialists are able to share their knowledge and experiences.

Biljana Macura, D. Bojovic, I. Petric, N. Ćosić, M. Tadić, I. Jarić, J. Knežević, J. Špirić et al.

Nihad Omerović, Ruzmir Avdić, N. Alić

The present paper analyzes the operation of the plant for washing stone aggregate 0/2 mm. Researches were conducted on a semi fixed plant for washing aggregates at the open pit 'Drenik' in Srebrenik. Positions of exploration works were on dispenser entrance points, hydrocyclones, distribution system for water supply rubber belt conveyors, etc.). The methods for measuring material flow, calculation the capacity of conveyors, laboratory methods for grain-size distribution of the obtained material were used in this work. The research results are present in the form of tabular data and dependence diagrams of filler content (fractions of technical stone aggregate, granulation -0.063 mm) on capacity of dosed material.

Nihad Omerović, Ruzmir Avdić, N. Alić

This paper deals with the production of limestone at the stable plant separation of the open pit 'Duboki potok-Bijela rijeka'. Besides that, the effects of different levels of production and material flows were researched. Research was carried out in a fixed plant separation of the open pit limestone 'Duboki potok-Bijela rijeka' in Duboki Potok. Positions of research were on the secondary part of separation (impact crusher, routers materials, funnels, rubber conveyors, vibrating screens, etc). In the course of using different methods of measuring material flow, calculating capacity conveyors, laboratory methods where used in measuring size and distribution obtained material, and particle shape. The research results were reported in: - particle size distribution diagrams of the obtained aggregate stone with the best bands of particle size distribution - defining the functional dependence of impact crusher gap size distribution and structure of the obtained materials.

Zoran Kukrić, L. Topalić-Trivunović, B. Kukavica, S. Matoš, Svjetlana S. Pavičić, M. Boroja, A. Savić

Samples of stinging nettle or common nettle (Urtica dioica L.) were collected from the area of Banja Luka. To measure and evaluate the content of chlorophyll (a and b), carotenoids, and soluble proteins, as well as peroxidase activity (POD, EC 1.11.1.7.), fresh nettle leaves of different developmental stages were used. Dried nettle leaves were used to obtain ethanol extract. The dry residue of ethanol extract was dissolved in metha- nol and the obtained solution was used to determine the content of total phenols, flavo- noids, flavonols, as well as non-enzymatic antioxidant activity and antimicrobial activity. The non-enzymatic antioxidant activity was determined by different methods: FRAP, DPPH, and ABTS. The results were compared to those of standard substances like vitamin C, BHT, and BHA. Antimicrobial activity was screened by using macrodilution method. The obtained results showed insignificantly higher content of chlorophyll, caroteno- ids, and proteins in young nettle leaves as well as an increase in the soluble peroxidase activities. Native electrophoresis of the soluble fraction showed the presence of two pero- xidase isophorms in the soluble protein fraction of nettle leaves. The total phenolic content in nettle extracts amounted to 208.37 mg GAE/gdw,, the content of total flavonoids was 20.29 mg QE/gdw, and the content of total flavonols was 22.83 mg QE/gdw. The antioxidant activity determined by FRAP method was 7.50 mM Fe(II)/gdw, whereas the antioxidant activity measured by using DPPH and ABTS methods, with IC50 values, were 31.38 and 23.55 μg mL -1 , respectively. These results showed the weak and moderate an- tioxidant capacity of stinging nettle. Extract of Urtica dioica L. was tested for antibacterial acivity against various Gram- positive and Gram-negative bacteria: Bacillus subtilis IP 5832, Lactobacillus plantarum 299v (Lp299v), Pseudomonas aeruginosa, and Escherichia coli isolated from food and Escherichia coli isolated from urine samples. Ampicillin, erythromycin, ciprofloxacin, and gentamicin were used as positive control. The results showed that minimum inhibi- tory concentration (MIC) and minimum bactericidal concentration (MBC) of the extract ranged from 9.05 to more than 149.93 mg mL -1 .

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