AimTo explore the prevalence of amebiasis in inflammatory bowel disease (IBD), Crohn’s disease and ulcerative colitis, in patients in Clinical hospital Mostar (Bosnia and Herzegovina, region of Herzegovina).MethodsIn this study, Entamoeba histolytica/dispar prevalence was investigated in fresh faeces by native microscopy and immunochromatographic rapid assay “RIDA®QUICK Entamoeba test”, in 119 cases of new found IBD patients, 84 of ulcerative colitis and 35 of Crohn’s disease and in control group who had also 119 patients who didn’t have any gastrointestinal complaints. IBD diagnosis was established by standard diagnostic procedures (anamnesis, clinical manifestations, laboratory, endoscopy and biopsy).ResultsEntamoeba histolytica/dispar were found in 19 (16.0 %) of a total of 119 cases, 12 (14.3 %) of the 84 patients with ulcerative colitis and 7 (20.0 %) of the 35 patients with Crohn’s disease. As for the 119 patients in the control group who had not any gastrointestinal complaints, 2 (1.7 %) patients were found to have E. histolytica/dispar in their faeces. Amoeba prevalence in the patient group was determined to be significantly higher in group with Crohn’s disease, ulcerative colitis and IBD total than in the control group (p < 0.001).ConclusionAmeba infections in patients with Crohn’s disease and ulcerative colitis, have a greater prevalence compared to the normal population.

We investigated if a femoral nerve block (FNB) for patients with a proximal femoral fracture (PFF) and administered by an orthopaedic registrar (OR) instead of an anaesthesiology registrar (AR) lowers the lead time to block and reduces the total amount of rescue analgesics during the preoperative phase. 205 patients were included in a prospective observational cohort study. The main outcome variable was rescue analgesics as total intravenous morphine prior to surgery. All results were adjusted for confounding using age, sex, cognitive dysfunction, and ASA classification. The OR group (n = 135) was over 2 hours faster in performing the block compared to the AR group (n = 70) but was nonetheless correlated with an increased amount of rescue analgesics during the study, 2.4 mg morphine (95% CI 0.0–4.9) more compared to the AR group. We found no difference between the groups in the risk of adverse events. We conclude that, for patients with an acute PFF and with morphine consumption as end point, how soon from arrival to hospital the patients receive a FNB is of lesser importance than who is administering it. Based on our results we recommend that emergency hospitals should have routines for anaesthesiologists performing FNB on this frail patient group.

Introduction: Cardiac autonomic neuropathy (CAN) is important, but often neglected complication of diabetes, that substantially contributes to diabetes-related morbidity and mortality. The majority of diabetic patients have subclinical CAN. Therefore, screening for CAN in patients with diabetes is essential. The aim of this study was to assess the prevalence of subclinical CAN in real-life clinical setting at primary health care institution. We also aimed to determine, which routine clinical and laboratory parameters could serve as predictors of CAN. Methods: We conducted a cross-sectional, prospective, observational study that included 50 consecutive patients with type 2 diabetes treated in the primary health care institution. Gender, age, duration of diabetes, glycated hemoglobin (HbA1c) levels, electrocardiogram, blood pressure, the presence of paresthesia, deep and superficial neuropathy, foot skin lesions and the presence of pulselessness of artery dorsalis pedis and tibialis posterior were recorded. The diagnosis of CAN was made if the patients met two out of three criteria: postural hypotension, increased resting heart rate and corrected QT interval prolongation. Results: Patients had a median age of 59.0 (51.0 – 64.0) years and median duration of diabetes of 9.0 (6.0 – 11.0) years. CAN was present in 19 patients (38%). Patients with CAN had greater duration of diabetes and 2% higher HbA1c. They also had higher prevalence of peripheral neuropathy, foot skin lesions and peripheral artery disease. The presence of peripheral deep neuropathy was the best predictor of CAN with a specificity of 64.5% (45.4 80.8) and sensitivity of 79.0% (54.4 93.9). Conclusion: CAN is a common complication in our cohort of patients with diabetes. Simple routine clinical and laboratory parameters may be useful in detecting patients at high risk for CAN. 1 Public Educationional Healthcare Center Tuzla –Family Medicine Teaching Center 2 Public Healthcare Center GracanicaDepartment of Family Medicine; 3 General Hospital Gracanica; 4 University Clinical Center Tuzla and European University Kallos Tuzla. Azijada Beganlic1, Albina Softic2, Jasmin Alic2, Menedin Causi3, Senada Selmanovic1, Fuad Pasic4, Munevera Becarevic4 Corresponding author: Azijada Beganlic, M.D., PhD, Professor of medicine, Public Educationional Healthcare Center Tuzla, Family Medicine Teaching Center; Albina i Franje Herljevica 1, Tuzla 75000; Bosnia and Herzegovina; Phone number: 00387 63 992 465; E-mail: azijada_beganlic@yahoo.com DOI: 10.21040/eom/2016.2.3.1 Received: September 1st 2016 Accepted: September 9th 2016 Published: September 15th 2016 Copyright: © Copyright by Association for Endocrine Oncology and Metabolism. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/ licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Funding: None. Conflict of interest statement: The authors declare that they have no conflict of interest. Data Availability Statement: All relevant data are within the paper.

In the current climate of increased influx of migrants into European countries, understanding how to engage with diversity in order to utilize it as a resource is becoming essential for supporting inclusion in education and society. Schools are often first sites of intercultural experiences for children and young people recently arrived to a host country. Educators and other professionals in public services facilitating equality of opportunity and equality of access for diverse school communities often lack opportunities to develop skills and insights relevant to new everyday challenges. The LUCIDE (Languages in Urban Settings for Inclusion and Diversity in Europe) network of research partners was established with the aim to provide insights and develop guidance that would support institutions (schools, councils, universities, hospitals) and local and national economies to gain better understanding of complexities involved in providing services in highly diverse contexts. LUCIDE consisted of 16 partners based in 13 European cities (two in London) and two cities outside of Europe. All partners had pre-existing activities focused on researching and promoting multilingualism within urban contexts of different types. Some cities in the LUCIDE network have had multilingualism as an integral part of their functioning over a long period throughout centuries of their history, while others started experiencing it as a recent impact of new patterns of migration. The European city partners were Athens, Dublin, Hamburg, Limassol, London, Madrid, Osijek, Oslo, Rome, Sofia, Strasbourg, Utrecht, and Varna. The two outof-Europe partners were Ottawa and Melbourne. This feature in the London Review of Education brings to its readers papers from four LUCIDE partner cities: Limassol, Rome, Strasbourg, and Ottawa (with the latter’s research here comparing the services in Montreal and Vancouver). These papers have been selected to provide insights into new explorations of multilingualism in cosmopolitan cities. The term ‘cosmopolitan cities’ is used to place the emphasis on a positive approach to diversity stemming from the premise that diversity is a resource for individuals and societies. The LUCIDE network directly built upon the LETPP (Languages in Europe: Theory, Policy and Practice) project, funded in 2010 by the EU Lifelong Learning Programme. The LETPP vision was that multilingual cities would be trailblazing new ways to approach and utilize diversity. The LUCIDE network proposal aimed to extend the aims and delivery of this project, and was developed and funded by the European Commission Lifelong Learning Programme from December 2011 to November 2014. Its main activities were to carry out research as the basis for developing guidelines for multilingual cities relating to the following five spheres:

OBJECTIVE The aim is to analyze how schizophrenia is pharmacologically treated in seven CEE countries: Croatia, Estonia, Hungary, Poland, Serbia, Slovakia and Slovenia. METHODS Psychiatrists from selected centers in each of participating countries were asked to complete a pre-defined questionnaire on their current clinical practice. Information on protocols and resource utilization in schizophrenia treatment was included and derived from randomly selected patient medical records. Expert opinions on country-wide treatment patterns were additionally sought. This sub-analysis focuses on pharmacological treatment patterns in the last six months and over the course of the disease. RESULTS 961 patients' data show that during last six months the most commonly prescribed medications were oral atypical antipsychotics: olanzapine (n=268), clozapine (n=234) and risperidone (n=160). The most frequently prescribed atypical antipsychotics over course of disease were: risperidone (54.5%), olanzapine (52.4%) and clozapine (35.1%), along with haloperidol (39.3%). Experts reported risperidone (four countries) and olanzapine (three countries) as first-line treatment, with the same two medications prescribed as second-line treatment. Clozapine was the most reported medication for refractory patients. Approximately 22% of patients received polypharmacy with antipsychotics in at least one period over the disease course. Mean time since diagnosis was 13.1 years and on average 4.8 treatment courses received during that period. Anxiolytics (70%), antidepressants (42%), mood-stabilizers (27%) were also prescribed, with diazepam (35.4%), sertraline (10.5%), valproic acid (17.5%) the most commonly reported, respectively, in each group. The most frequently reported treatment change was switch from one oral atypical antipsychotic to another (51%). CONCLUSION Oral atypical antipsychotics, mostly older drugs (risperidone, olanzapine, clozapine), were most commonly prescribed for schizophrenia treatment in participating countries. Given that results are from the first large-scale analysis of RWD, we believe these findings can be a benchmark for future real-world studies, which could contribute to the optimization of treatment for this debilitating disease.

Lung cancer is usually presented with cough, dyspnea, pain and weight loss, which is overlapping with symptoms of other lung diseases such as pulmonary fibrosis. Pulmonary fibrosis shows characteristic reticular and nodular pattern, while lung cancers are mostly presented with infiltrative mass, thick-walled cavitations or a solitary nodule with spiculated borders. If the diagnosis is established based on clinical symptoms and CT findings, it would be a misapprehension. We report a case of lung adenocarcinoma whose symptoms as well as clinical images overlapped strongly with pulmonary fibrosis. The patient’s non-productive cough, progressive dyspnea, restrictive pattern of pulmonary function test and CT scans (showing reticular interstitial opacities) were all indicative of pulmonary fibrosis. The patient underwent a treatment consisting of corticosteroids and antibiotics, to no avail. Histopathology of the lung showed that the patient suffered from mucinous adenocarcinoma. Albeit the immunohistochemical staining was not consistent with lung adenocarcinoma, tumor’s morphological characteristics were consistent, and were used to make the definitive diagnosis. Given the fact that radiography cannot always make a clear-cut difference between pulmonary fibrosis and lung adenocarcinomas, and that clinical symptoms often overlap, histological examination should be considered as gold standard for diagnosis of lung adenocarcinoma.