The Pehare Viaduct is located on the 2nd subsection of the Zenica Bypass Motorway at Corridor Vc which is under construction. Based on engineering geological mapping and performed investigation works, it was found that the viaduct is placed in two completely different geological zones (chalk flysch and oligomiocene sediments) separated by the fault zone. The oligomiocene complex is characterized as a landslide. During the preparation of Geotechnical Performance Study Mission G31, an additional investigation works were carried out on piers location, and inclinometers were installed. The results of the measurements on the inclinometers have shown that there are significant displacements at higher depths, resulting in a change of the foundation construction compared to the solution given in the main design. The problem of terrain stability on the one part of theviaduct and the foundation in two different geological zones with fault between them, emphasises this viaduct as one of the most complex on this subsection. This paper describes the structure of the viaduct, viaduct foundations based on the determined sliding zones, and a review of the geotechnical analysis with the risk analysis.

It is certain that the first steps of the vehicle drives each individual person were made in karting vehicle. Additional adrenaline and increase driving pleasure gives extremely high noise and the smell of combustion products that may still endure when the ride takes place on an open track during sunny days. However, for many years karting rides take place indoors where it is necessary to provide a special ventilation system for undesirable combustion products. In order to avoid problems of air pollution indoors, reduce noise, and raise awareness of young generations in terms of preservation of the environment, today is increasingly use of electric karting. Having in mind the multiple benefits of electric drive, a reconstruction of karting vehicle with petrol engine into electric karting is presented in the paper. A special attention was paid to the selection of the electric powertrain and battery storage units for electricity, as well as dynamic characteristics of the reconstructed electric vehicle.

Laser scanning does not provide unlimited geometrical accuracy and integrity when scanning complex objects. Scanning systems have a minimum and maximum range in which they operate, depending on the technical characteristics. Scanning below or above these limits results in gross errors and registering of incorrect data. Laser scanners can have difficulties with certain materials such as marble and reflective surfaces. This paper presents the results of laser scanning of a complex monument of cultural and historical heritage using two different types of terrestrial laser scanners. Afterwards, the comparison and analysis of the results are shown. The scanners used were terrestrial laser scanners Faro Focus 3D (phase mode distance measurements) and STONEX X300 (pulse mode distance measurements).

Specific microRNAs (miRNAs) are packaged in exosomes that regulate processes in tumor development and progression. The current study focuses on the influence of exosomal miRNAs in the pathogenesis of epithelial ovarian cancer (EOC). MiRNA profiles were determined in exosomes from plasma of 106 EOC patients, eight ovarian cystadenoma patients, and 29 healthy women by TaqMan real‐time PCR‐based miRNA array cards containing 48 different miRNAs. In cell culture experiments, the impact of miR‐200b and miR‐320 was determined on proliferation and apoptosis of ovarian cancer cell lines. We report that miR‐21 (P = 0.0001), miR‐100 (P = 0.034), miR‐200b (P = 0.008), and miR‐320 (P = 0.034) are significantly enriched, whereas miR‐16 (P = 0.009), miR‐93 (P = 0.014), miR‐126 (P = 0.012), and miR‐223 (P = 0.029) are underrepresented in exosomes from plasma of EOC patients as compared to those of healthy women. The levels of exosomal miR‐23a (P = 0.009, 0.008) and miR‐92a (P = 009, 0.034) were lower in ovarian cystadenoma patients than in EOC patients and healthy women, respectively. The exosomal levels of miR‐200b correlated with the tumor marker CA125 (P = 0.002) and patient overall survival (P = 0.019). MiR‐200b influenced cell proliferation (P = 0.0001) and apoptosis (P < 0.008). Our findings reveal specific exosomal miRNA patterns in EOC and ovarian cystadenoma patients, which are indicative of a role of these miRNAs in the pathogenesis of EOC.

Contrary to its conventional image as a social-democratic paragon, the Danish welfare state has, in recent decades, been undergoing significant changes as a response to the intrusion into the social sphere by self-regulating markets and a final departure from Keynesian politics of universalism and solidarity. This article examines the evident decline of the Nordic model as a result of neoliberal globalisation and establishes an association between the erosion of the welfare state and the emergence of fascist political sentiment in Denmark. An analysis of the Danish People's party and its growing public support among the disenfranchised working class communities in Denmark demonstrates how those overlooked by the free market and unrepresented by the liberal left become increasingly more receptive to the proposed social agendas of the far right campaigns.

In recent years, noticeable progress has been made in the development of quantum equipment, reflected through the number of successful demonstrations of Quantum Key Distribution (QKD) technology. Although they showcase the great achievements of QKD, many practical difficulties still need to be resolved. Inspired by the significant similarity between mobile ad-hoc networks and QKD technology, we propose a novel quality of service (QoS) model including new metrics for determining the states of public and quantum channels as well as a comprehensive metric of the QKD link. We also propose a novel routing protocol to achieve high-level scalability and minimize consumption of cryptographic keys. Given the limited mobility of nodes in QKD networks, our routing protocol uses the geographical distance and calculated link states to determine the optimal route. It also benefits from a caching mechanism and detection of returning loops to provide effective forwarding while minimizing key consumption and achieving the desired utilization of network links. Simulation results are presented to demonstrate the validity and accuracy of the proposed solutions.

Introduction: Dry needling is a therapeutic procedure using the insertion of thin needles through the skin into myofascial trigger points (MTrPs), muscular or connective tissue with the aim to reduce pain intensity. The objective of this systematic review is to analyze the literature for the efficacy of the dry needle technique in pain reduction in conditions of musculoskeletal pain caused by MTrPs. Reference Sources: Web of Science, Scopus and EBSCOhost database were searched for studies and e-books published from January 2010 to December 2018. Studies Selection: We included randomized controlled studies, prospective and longitudinal studies, and case studies which analyzed the efficacy of dry needling for musculoskeletal pain reduction. Data Extraction Method: The studies, which satisfied criteria for inclusion were further analyzed. The primary instrument of the evaluation was pain intensity analyses. Results: Dry needling treatment is efficient in pain intensity reduction in patients who suffer musculoskeletal pain and is more efficient compared to sham dry needling treatment. In addition, different techniques of dry needling are efficient in the treatment of myofascial pain syndrome. Conclusion: Based on systematic review of the literature, dry needling, independently or as an addition to other intervention, is recommended for treatment of musculoskeletal pain conditions caused by myofascial trigger points. Various techniques of dry needling treatment are almost equally efficient in myofascial pain intensity reduction.

3D geological models can be very useful in many geological, mining and other engineering activities. Constructed model should serve as a 3D geodatabase for variety of input data. Study area represents one of the bauxite bearing sites, Crvene Stijene, near Jajce (Bosnia & Herzegovina). Presented methodology includes the integration, digitalization, organisation and visualisation of different types of input data (600 boreholes, geological maps and sections, DEM, structural measurements from the surface and in the tunnels and adits) in the 3D geological database. In the modeling workflow, different types of geological objects were modeled with different interpolation algorithms. Used interpolation algorithm depends on complexity of geological object, character and spatial distribution of input data. The model is interactive which is important because there are constantly ongoing research and exploitation activities: boreholes, underground mining objects, etc. that can be easily imported into the model. 3D geological model represents a basis for planning new scientific research and mining activity.