Background: Metal-nicotianamine transporter (YSL) family protein belongs to the oligopeptide heavy metal transporter group, as characterized in Arabidopsis thaliana. Oligopeptide transporters (OPTs) are a group of membrane-localized proteins, involved in different transport mechanisms, contributing to nitrogen mobilization, glutathione transport and long-distance metal distribution. Metal-nicotianamine transporter gene 3 (YSL3) incorporates the oligopeptide transporter domain, found to transfer several heavy metals in diverse plant species, and among them cadmium transport in Brassica oleracea. Objective: To evaluate and confirm the expression of Metal-nicotianamine transporter (YSL3) under cadmium stress. Studied species: Brassica oleracea var. acephala Study site and dates: Brassica oleracea var. acephala samples were collected from Blagaj region, Bosnia and Herzegovina. Methods: Through a simple bioinformatic approach the interactome partner of Metal-nicotianamine transporter (YSL3) was discovered and annotated. Oligopeptide transporter 3 (OPT3) and Metal-nicotianamine transporter (YSL3) genes were checked for expression levels under cadmium stress. Results: We have identified a strong interacting partner of YSL3, later confirmed as Oligopeptide transporter 3 (OPT3) protein in Brassica oleracea. The in vitro expression analysis by using a qRT-PCR revealed a significant upregulation of YSL3 and OPT3, during Cd stress. Conclusions: These findings indicate that the represented in-silico approach, followed by in vitro gene expression study, successfully confirmed YSL3 and identified OPT3 as a new gene, in correlation to cadmium stress.

The purpose of this paper is to investigate the importance of human capital, as location determinant for the foreign direct investment (FDI) decisions in the Western Balkan Countries between 2008 and 2016. Apart from the human capital indicators, several location determinants were used as control variables. The hypothesis has been tested by employing correlation and regression analysis. The empirical findings revealed the positive impact of primary education and the negative impact of tertiary education on the inflows. The analysis showed that political stability and control of corruption are more important location determinants than human capital. Therefore, the policy measures should be directed towards the improvement of institutional framework and creating a supporting environment for the FDI inflows.

Pre‐exposure prophylaxis (PrEP) for HIV infection is an important intervention for control of the HIV epidemic. The incidence of HIV infection is increasing in the countries of Central and Eastern Europe (CEE). Therefore, we investigated the change in PrEP use in CEE over time.

Automated vehicles are expected to become a part of the road traffic in the near future. This upcoming change raises concerns on how human road users, e.g., cyclists or pedestrians, would interact with them to ensure safe communication on the road. Previous work focused primarily on the scenario in which a young adult without impairments crosses a street in front of an automated vehicle. Several road user groups, such as children, seniors, or people with special needs, in roles of pedestrians and cyclists, are not considered in this scenario. On top of this, cultural differences are rarely considered. To ensure that future traffic is safe and accessible for all citizens, we aim to address inclusive communication between automated vehicles and vulnerable road users. In this workshop, we will discuss and exchange methods, tools, and scenarios applicable for inclusive communication, identify the most relevant research gaps, and connect people for future collaborations.

The levels of polycyclic aromatic hydrocarbons (PAHs) were determined in the industrial zone, near the center of Banja Luka and river Vrbas, Republic of Srpska, Bosnia and Herzegovina. In the presented research, the total concentration of the PAHs in research area ranged from 0.356 to 11.49 mg/kg, with mean values of 1.99 mg/kg indicated that soil was heavily contaminated (max limit 1 mg/kg) and polluted with pollutant of class III ranging from 1 to 5 mg/kg. The possible sources of PAHs in the soils were estimated by using diagnostic ratios (LMW/HMW (low/high molecular weights), Fluo/(Fluo+Pyr) (fluoranthene/(fluoranthene+pyrene)), BaA/(BaA+Chr) (benzo[a]anthracene/(benzo[a] anthracene+chrysene)) and IcdP/(IcdP+BghiP) (indeno[1,2,3-cd]pyrene/(indeno[1,2,3-cd]pyrene + benzo[g,h,i]perylene))) and factor analysis (principal component analysis). The ratios showed that the PAHs in soil have both pyrogenic and petrogenic sources. Pyrogenic source is predominant. Petrogenic sources also have a significant contribution in the study area. Principal component analysis has shown that both industrial and human activities are the cause of pollution. The first factor is in relation to burning (pyrogenic origin). This factor explained 76.72% of total variance. The second factor is petrogenic, with 7.81% of total variance. PAHs in research area is a result of in general anthropogenic factors.

In this paper we apply the h-generated fuzzy implications to prove a number of results which are of fundamental importance to the theory of fuzzy and vague functional and multivalued dependencies defined on given scheme. Our research is motivated by the fact that some analogous results already hold true for the families of f- and g-generated fuzzy implications, and the fact that these three collections of implications share many similar mutual properties. While some of the aforementioned implications are introduced in order to be applied in approximate reasoning, the results derived in this paper represent the main tool in the process of automation and are also used to complement the resolution principle. More precisely, the main result of this research states that the fact that some fuzzy (vague) relation instance r, |r| = 2, satisfies some fuzzy (vague) functional or fuzzy (vague) multivalued dependency c /∈ C (under assumption that r satisfies some set C of fuzzy (vague) functional and fuzzy (vague) multivalued dependencies), yields that the fuzzy formula attached to c is valid whenever all of the fuzzy formulas attached to the elements of C are valid. What is more important is that the opposite claim is also proven. Its importance stems from the fact that the verification by hand, which means purely theoretical verification, that C implies c is not required anymore. Now, in order to prove that some C yields some c, it is enough to make the use of the resolution principle, and automatically verify whether or not the set of the attached fuzzy formulas yields the fuzzy formula attached to c. In the case of affirmative answer, the desired dependency follows. The research conducted in this paper represent a natural generalization of our previous research since it includes and considers both, fuzzy and vague theories.

We obtain precise estimates for the number of singularities of Selberg’s and Ruelle’s zeta functions for compact, higher-dimensional, locally symmetric Riemannian manifolds of strictly negative sectional curvature. The methods applied in this research represent a generalization of the methods described in the case of a compact Riemann surface. In particular, this includes an application of the Phragmen-Lindelof theorem, the variation of the argument of certain zeta functions, as well as the use of some classical analytic number theory techniques.

Este trabalho teve o objetivo de estudar a influencia que a informacao light exerce no consumidor em termos sensorial e de atitudes. Os dados foram obtidos por meio da aplicacao de um instrumento de coleta padronizado, teste de aceitacao sensorial e determinacao do teor de gordura de diferentes marcas de requeijao light por meio do Metodo de Gerber. A analise estatistica foi realizada por meio da estatistica descritiva, como frequencia, alem do teste t para amostra pareada e correlacao de Pearson, adotando nivel de significância de 5%. Os resultados obtidos a partir da analise dos questionarios mostraram que existe elevada demanda em relacao aos produtos light , estando essa procura relacionada especialmente a saude. Alem disso, foi possivel detectar que apesar dos entrevistados terem alegado entender o termo light , muitos entrevistados apresentaram um conceito erroneo do termo. No teste de influencia da informacao light na aceitacao sensorial de requeijao, observou-se que 38% dos provadores nao tiveram sua aceitacao influenciada pela informacao light , 34% foram influenciados negativamente e 28% foram influenciados positivamente. Alem disso, por meio da determinacao do teor de gordura de requeijao light , observou-se que todas as marcas possuem reducao superior a 25%, atendendo aos aspectos legais para usar o termo light em seus rotulos. Assim, conclui-se que os alimentos light ainda precisam avancar em estudos para diminuir a influencia negativa da expressao light , bem como devem apresentar aos consumidores mais esclarecimentos sobre o termo e, tambem, em caracterizacao da composicao centesimal e padronizacao de produtos.

The study aims to critically analyze the EU's political identity and how the migrant crisis embodies the most challenging political issue facing the E.U., implicating growing xenophobia and questioning European multiculturalism. Moreover, the author provides insight into the migrant crisis's socio-political and security challenges, followed by ethnographic research of the migrant's religious identity within the Balkan route. Migrations are a central issue for Europe's future, security, and identity. The EU's cultural integrity remains unclear, and the migrant crisis opens up a multiculturalism discourse. The nationstate model has undergone significant globalized world changes, becoming less sustainable and less critical for cultural, political, and economic processes. Due to the growing economic insecurity and the fear of losing national identities in an environment of globalized culture, some have perceived multiculturalism as a threat. The humanitarian and security discourse reflects the micro-level of the situation on the ground and the mass media's macro levels and political action. Acceptance of ethnoreligious or political diversity does not relieve immigrants of the duty to recognize all the rules necessary to conduct productive coexistence. Migrants' participation in socio-economic and political systems means realizing the preconditions for the beginning of cultural integration. The crisis triggered an avalanche 1 BSc Psychology, Economics, MSc Security Studies,Criminal Justice and Law Enforcement, Diploma,(MBTA),Mindfulness Based Transactional Analysis Research, Society and Development, v. 9, n.10, e4809108685, 2020 (CC BY 4.0) | ISSN 2525-3409 | DOI: http://dx.doi.org/10.33448/rsd-v9i10.8685 2 of anti-Islam sentiments that became a reference matrix for radical populism. The sense of identification with the housing society-Bosniaks, where Islamic regulations on the matrix are legitimized by recognizing a universal theological pattern, is a symbolic moment and a participative approach to understanding both religion and integration. Constructing immigrants as a group, whether they are migrants, refugees, or asylum seekers, tends to encourage the perception that "their "interests, values, and traditions are competing with "ours, "stimulating negative emotions in the form of prejudice.

Checkpoint inhibitor (CPI) therapy has significantly improved overall survival for metastatic melanoma, and is now approved for use in the adjuvant setting. Modulating the immune system is recognized to cause cutaneous immune‐related adverse events (irAEs). We conducted a retrospective observational cohort study of adult patients with melanoma at our tertiary referral centre, who received CPI therapy from 2006 to March 2018. This is the single largest study of cutaneous irAEs occurring on CPI therapy in patients with melanoma to date and encompasses 12 years. The results showed that cutaneous toxicity occurs in 24% of patients but is generally manageable, with < 5% patients discontinuing treatment.