Edin Jusufovic1,2, Besim Prnjavorac5,6 , Ermina Iljazovic2, Mitja Kosnik3, dragan Keser1,2 Peter Korosec3, Jugoslav Stahov4, Edin Zukic1, Rifat Sejdinovic5, Ekrem Ajanovic5 Policlinic for Pulmonary diseases, Health Medical Centre Tuzla, Bosnia and Herzegovina1 Medical Faculty, University in Tuzla, Bosnia and Herzegovina2 University Clinic of Respiratory and Allergic diseases Golnik, Slovenia3 Faculty of Science, University in Tuzla, Bosnia and Herzegovina4 department of Internal Medicine, General Hospital Tesanj, Bosnia and Herzegovina5 Faculty of Pharmacy, University of Sarajevo, Sarajevo, Bosnia and Herzegovina6

Within the framework of a mathematically well-defined coupled-channel T-matrix model we have improved the existing multichannel pole-extraction procedure based on the numerical analytic continuation of the channel propagator, and for the first time we present the full set of pole parameters for already published amplitudes. Standard single-channel pole-extraction method (speed plot) was then applied to those amplitudes and resulting sets of T-matrix poles were inspected. The anomaly has been established that in some partial waves the pole values extracted using the standard single-channel methods differ not only from the values obtained using the analytic continuation method, but also change from one reaction to another. Inspired by this peculiarity, we have developed a new single-channel pole-extraction method based solely on the assumption of the partial wave analyticity. Since the speed plot turns out to be the lowest order term of the proposed method, the anomaly is understood and resolved.

The needle biopsies from 60 transplanted and native kidneys have been processed and a prospective analysis of pattern, intensity and distribution of immunoglobulin deposits (IgA, IgG and IgM) and complement components (C3c and C1q) identified in these lesions has been carried out by immunohistochemistry with three step immunoperoxidase, in the period from 2000 to 2004. Those deposits were previously detected and analyzed by immunofluorescence. The samples consisted of 30 renal biopsies, previously diagnosed with glomerulonephritis and positive immunofluorescence and 30 renal biopsies without morphologic changes and deposits on immunofluorescence. 78,7% of the analyzed samples showed the identical results of the deposits of immunoglobulin and components of the complement with both, immunohistochemistry and immunofluorescence method. Sensitivity of the immunohistochemistry method with three step immunoperoxidase for all analyzed immunoglobulin and complement components is high (0,93), while specificity for the same method is 0,79. Standardized method of the three step immunoperoxidase on the paraffin embedded, formalin fixed needle renal biopsies could successfully replace the immunofluorescence method in diagnostic of GN, with the emphasis on a follow up and control of each single step in the procedure of the method.

The dispersion relations are used to perform an analytical continuation of the πN scattering amplitude D + to the Cheng-Dashen point and to calculate the πN sigma term. The dispersion relations were evaluated along two different families of dispersion curves passing through different kinematical regions in the s-channel physical region. The obtained results for the sigma term are still within the error bars of the previous Karlsruhe result.

Th e needle biopsies from  transplanted and native kidneys have been processed and a pro- spective analysis of pattern, intensity and distribution of immunoglobulin deposits (IgA, IgG and IgM) and complement components (Cc and Cq) identifi ed in these lesions has been carried out by immunohistochemistry with three step immunoperoxidase, in the period from  to . Th ose deposits were previously detected and analyzed by immunofl uorescence. Th e samples consisted of  renal biopsies, previously diagnosed with glomerulonephritis and positive immunofl uorescence and  renal biopsies without morphologic changes and deposits on immunofl uorescence. , of the analyzed samples showed the identical results of the deposits of immunoglobulin and components of the complement with both, immuno- histochemistry and immunofl uorescence method. Sensitivity of the immunohistochemistry method with three step immunoperoxidase for all analyzed immunoglobulin and complement components is high (,), while specifi city for the same method is ,. Standardized method of the three step immunoperoxidase on the paraffi n embedded, formalin fi xed needle renal biopsies could successfully replace the immunofl uorescence method in diagnostic of GN, with the emphasis on a follow up and control of each single step in the procedure of the method.

Complete sets of measurements for pion-nucleon scattering in the N*(1440) resonance region have been made since 1980, when the landmark KarlsruheHelsinki (KH) and Carnegie Mellon-Berkeley (CMB) partial wave analyses (PWA) were completed. These measurements consist of differential cross sections and analyzing powers for elastic scattering and charge exchange and spin rotation parameters for elastic scattering in the momentum interval 0.4–0.7 GeV/c. The program culminated with measurements of π−p → Neutrals (charge exchange, multiple π final states, η production, and inverse photoproduction) by the Crystal Ball Collaboration at Brookhaven National Laboratory. Resonance parameters for the N*(1440) in the Review of Particle Physics by the Particle Data Group have been obtained from the KH and CMB analyses. The 2006 edition also includes the analysis by George Washington University (GWU), but the parameters were unchanged. An example of the data is presented along with comparisons to PWA.

Within the framework of a mathematically well defined coupled-channel T-matrix model we have improved the existing multi-channel pole-extraction procedure based on the numerical analytic continuation of the channel propagator, and for the first time we present the full set of pole parameters for already published amplitudes. Standard single-channel pole-extraction method (speed plot) was then applied to those amplitudes, and resulting sets of T-matrix poles were inspected. The anomaly has been established that in some partial waves the pole values extracted using the standard singlechannel methods differ not only from the values obtained using the analytic continuation method, but also change from one reaction to another. Inspired by this peculiarity, we have developed a new single-channel pole-extraction method based solely on the assumption of the partial-wave analyticity. Since the standard pole-extraction procedures turn out to be the lowest-order term of the proposed method, the anomalies are understood and resolved.

Inspired by anomalies which the standard scattering matrix pole-extraction procedures have produced in a mathematically well defined coupled-channel model, we have developed a new method based solely on the assumption of partial-wave analyticity. The new method is simple and appli-cable not only to theoretical predictions but to the empirical partial-wave data as well. Since the standard pole-extraction procedures turn out to be the lowest-order term of the proposed method the anomalies are understood and resolved.

Dispersion relations along interior hyperbolas and a set of hyperbolas passing through the Cheng-Dashen point are used to calculate the pion-nucleon sigma term. The t-channel input is updated using the recent GWU partial wave solution and ππ phase shifts from calculations based on Roy equations. Obtained values for the sigma term are still within the error bars of the previous Karlsruhe result.

A dependence of the value of the pion-nucleon sigma term on higher partial waves is discussed. Two recent predictions of a high value of sigma term are scrutinezed. It has been concluded that the main reason for obtaining high values of the sigma term are input D waves that are not consistent with analyticity.