This paper shows the use of membrane filters in adsorption of solution of tetracycline hydrochloride on graphene materials. The adsorption process was monitored at different wavelengths, different pH values at certain time intervals. The absorbances of the solutions were measured by UV-Vis spectrophotometry at two wavelengths (275 nm and 356 nm), and three pH values (pH 4, pH 7 and pH 10) every 90 minutes for 6 hours of monitoring, with constant stirring in an ultrasonic bath. The results showed decrease in absorbance at both wavelength and in all three pH values which proved the adsorption of tetracycline hydrochloride on GO and rGO. The largest decrease in absorbance was 98.1%. The most suitable pH value for adsorption was pH 4. This paper used a unique approach to filtration through membrane filters, which in the future could lead to the development of membrane filters based on graphene materials.
Background: In this clinical pharmacological research, we dealt with the action of allopurinol on triglyceride levels in hyperuricemic patients.Methods: The study included 40 hyperuricemic patients, of both genders and different age groups, that were sorted by comorbid diagnoses in several subgroups. All patients were clinically treated in the period of three years both at UCC Sarajevo, and P.I. General Hospital "Abdulah Nakaš" Sarajevo. All clinical measurements were carried out using standard IFCC methods with the appropriate analysers.Results: The study was based on mean triglyceride levels before and after three and six months of treatment with allopurinol. It was found out that the mean triglyceride levels were not significantly different from the reference values prior to treatment (p = 0.846) and after three months of therapy (p=0.153). In contrast, after six months of treatment, triglyceride levels significantly increased compared to the reference values. In patients with a diagnosis of gout and metabolic syndrome, triglycerides were statistically significantly increased during the six months of observation. A statin group of patients showed a statistically significant increase in triglyceride levels after three months of therapy (p = 0.032), while, after six months their levels had decreased (p = 0.029). In patients with diabetes mellitus type II, triglycerides rose after three months of treatment (p = 0.039) and retained the same level after six months of observation.Conclusions: The analysis shows that the use of allopurinol has an effect on triglyceride levels in hyperuricemic patients.
The subject of the study in this pharmacological-clinical paper was the effect of allopurinol on the values of HDL and LDL in hyperuricemic patients. The research sample included 40 clinically treated patients of both sexes (UKC Sarajevo and JU General Hospital "Abdulah Nakaš" Sarajevo) and various age groups, which according to the diagnosis of the disease were classified into several subgroups (gout, diabetics, patients with metabolic syndrome). In subjects with established gout diagnosis, who were on the treatment with statins and allopurinol, it was found that the value of uric acid decreased after three and six months of use of allopurinol (p <0.05). It was found that the values of LDL fraction were statistically significantly decreased after 3 and 6 months of therapy (p <0.05), while the HDL fraction decreased after 3 months of therapy, but maintained the same to the sixth month of therapy. Also, in the treatment with allopurinol, subjects with metabolic syndrome with severe heart disease (hypertension present), the mean values of uric acid statistically decreased significantly, the values of LDL fractions were statistically significantly increased (p <0.05), while the values of HDL fraction increased after 3 months of therapy, so that later this value remained constant.
The increasing use of sun-creams containing organic UV-filters has led to increased concentration of these compounds in aquatic environment. Chlorinated water can convert these chemicals into chlorinated products whose toxic effects are of primary concern. The new compound may be more toxic than the starting primary compound. Many studies have shown that UV filters absorb UV light and decompose under solar irradiation, due to their unstable properties. This may lead to formation of certain by-products with harmful effects. Their decomposition products can cause allergic and toxic reactions to the human skin. This study follows the stability of most commonly used UV filters, homosalate, in conditions that include those existent in swimming pools. Stability of the homosalate in chlorinated water was studied in simulated swimming pool water samples. UV spectroscopy was used to follow the reaction of homosalate in presence of free chlorine. Water samples were filtered, acidified, and extracted by use of solid-phase extraction. Gas chromatography with mass spectrometry was used to identify the major transformation by-products. Under the experimental conditions, homosalate reacted with chlorine following zero order reaction. The chemical transformation of the homosalate in chlorinated water led to formation of chlorinated by-products that was identified as:
Many athletes use supplements in their diet as part of regular training or competition, thus enabling more intense training by encouraging faster recovery between workouts, minimizing interference caused by disease or injury and increasing competitive performance. These supplements, unlike medications, are not subject to rigorous efficiency and safety checks and tests. There is a risk with regard to those supplements which include positive doping test result as a consequence of presence of the prohibited substances not listed in the declaration of the preparation. The aim of this study was to examine the use of supplements among elite athletes by analyzing the forms for doping control, issued by the Agency for Anti-doping control of Bosnia and Herzegovina, performed in the period from 2010 to 2012. The study includes supplements whose use was reported by athletes in the period of the last 7 days (prior testing). The study results indicate the frequency of dietary supplements use of 34.5%. The most dominant group among users of dietary supplements were men aged between 18 and 29 years. From 152 users of dietary supplements 62.3% of them have used more than one product. The number of used supplements was an average of 2.9±2.8 products. Amino acids and proteins are the most commonly used dietary supplements. This study confirmed excessive use of dietary supplements among elite athletes and pointed to the need of necessary education and ensuring the availability of scientific and unbiased information, about the benefits and risks of dietary supplements use, to athletes..
Financial institutions in Bosnia and Herzegovina are increasingly finding themselves facing rapid increases in turbulence and complexity, leading to increased competition. As the wind of change started blowing, most banks (if not all) adopted the use of electronic banking (e-banking) for transaction, which is becoming the rule rather than exception. One of the reasons for this dynamic change in banking environment is the reliability and accuracy of this information if accurate data are inputted. Another reason is inherent benefit of e-banking to save time and magnificent efficiency in the speed in the transaction of banking activities and consequently enhancing the performance of banks. This paper is designed to find out the usage and problems of electronic banking on banks. The structure of the study is mainly exploratory and partly casual since it is also testing some hypothesis. Data collection method employed in this study is secondary, which comprises of electronic banking guidelines, financial summary of the bank over the years, journals and magazines of e-banking, computer data base accessed through the internet. The analysis tool used to test the hypotheses is simple linear regression and the student’s t-test. Theoretical contributions and practical implications of the findings are discussed and suggestions for future research are presented. Keywords: E-banking, Secondary Data, Linear Regression, Student’s T-Test.
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