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Publikacije (19)

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Gut-brain axis (GBA) represents a bidirectional communication between the central nervous system (CNS) and gastrointestinal (GI) tract. Microbiota found in GI tract has beneficial relationship with their host and can affect the brain, behavior. Studies performed on animals suggest that any change in the composition of microbiota might cause alternations in behavior. In the same way, changes in behavior such as stress, showed to affect the microbiota. Moreover, the composition of the maternal microbiome in pregnancy is known to adversely influence neonatal and infant health and preterm birth. Mother’s microbiome is inherited from the mother to children.

Lejla Mahmutović, E. Hasković, Damir Suljevic, M. Mitrašinović-Brulić

We investigated the impact of short-term experimental hyperthermia on differential blood cell count in rats Rattus norvegicus (male and female Wistar strain). The blood used for the analysis was obtained by the method of direct puncture of the heart. We analyzed the forms of leukocytes (granulocytes, lymphocytes and monocytes). The effect of short-term hyperthermia is statistically significant increase in lymphocyte count, and decrease in monocyte count. The changes in other leukocyte count are not statistically significant. Key words: hyperthermia, differential blood cell count

We investigated the impact of short-term experimental hyperthermia on glucose and haemogram in rats Rattus norvegicus (Wistar strain). The blood used for the analysis was obtained by the method of direct puncture of the heart. We analyzed the biochemical (glucose) and haematological parameters (RBC, WBC, hemoglobin, hematocrit, and haematological indices). The effect of short-term hyperthermia leads to a statistically significant increase of the number of erythrocytes, leukocytes and glucose concentration, whereas statistically significant reduction in hemoglobin concentration and hematological indices is evident. Key words: hyperthermia, haemogram, glucose concentration

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