diagnosed clinically as having acute appendicitis were recruited.60%were males, mean age 28±6years. Patients with previous medical, surgical or gynecological complaints, severe debilitating diseases like hypertension, diabetes, obesity, blood dyscrasias, anemia or previous surgeries were excluded from the study. All the patients later underwent either elective or emergency appendicectomy and the preoperative leukocyte count was compared with histopathology findings of resected appendix. Results: Total leukocyte count (TLC) was calculated in each case individually and was compared with the histopathological report from the laboratory accordingly. The sensitivity and specificity of WBC count was calculated by standard formula and was found to be 82.4% and 78.7% respectively. The positive predictive value of WBC count (raised TLC) in diagnosing acute appendicitis was 93.8% showing that raised TLC along with clinical history is really a diagnostic marker for this condition. Conclusion: Clinical history and physical examination are the key factors in diagnosing acute appendicitis as radiological findings are not much helpful. Although WBC count and raised TLC is not a standard criteria for diagnosing acute appendicitis, but still it is one of the strong predictor of this acute condition in emergency room and should strongly be considered while making the diagnosis of acute appendicitis.

Atherosclerosis is a pathological condition that begins in early childhood, but clinically the disease manifests in older age. The aim of work was to determine frequency of atherosclerosis risk factors in healthy school children. Cross-sectional study included 214 children in mean age 10,99+/-2,52 years, within range 7 to 15 years. Patients body mass index, blood pressure, lipid status, dietary habits, physical activity and sedentary habits have been evaluated. Cardiovascular risk factors are significantly present in children (P<0,05) i.e. one cardiovascular risk factor is present in 47/214 (21,96%) children, two risk factors had 25/214 (11,68%) children, while 17/214 (7,94%) children had three or more cardiovascular risk factors. Obesity was present in 20/214 (9,34%) children, while overweight was present in 23/214 (10,74%) children. Hypertension was present in 10/214 (4,67%) children, and it was significantly present (p<0,05) in obese and overweight children. Total cholesterol was increased in 17/214 (7,94%) children, LDL-cholesterol was increased in 11/214 (5,14%) [corrected], increased triglycerides had 4/214 (1,86%) children, while decreased HDL-cholesterol was found in (3/214, 1,40%) children. Unhealthy dietary habits were present in 45/214 (21,02%) children, 42/214 (19,62%) children is physically inactive, while sedentary habits were shown in 39/214 (18,22%) children. Research shows that a large number within study group has one or more cardiovascular risk factors that can lead to premature atherosclerosis. Using massive screening of cardiovascular risk factors, along with adequate physical activity, healthy dietary habits, reduced sedentary habits, doctors and teacher's education, parents and children can reduce premature clinical sequels in atherosclerotic process.